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The map label for this gene is nupX [H]

Identifier: 187731113

GI number: 187731113

Start: 754016

End: 755263

Strand: Direct

Name: nupX [H]

Synonym: SbBS512_E0805

Alternate gene names: 187731113

Gene position: 754016-755263 (Clockwise)

Preceding gene: 187731413

Following gene: 187733593

Centisome position: 16.33

GC content: 50.64

Gene sequence:

>1248_bases
ATGGATGTCATGAGAAGTGTTCTGGGAATGGTGGTATTGCTGACGATTGCGTTTTTGCTGTCAGTAAACAAGAAGAAGAT
CAGCCTGCGTACCGTTGGCGCGGCGTTAGTGTTACAGGTCGTGATTGGCGGGATTATGCTTTGGTTACCGGCAGGGCGTT
GGATCGCTGAAAAAGTCGCTTTTGGCGTGCATAAAGTGATGGCGTACAGCGACGCGGGTAGCGCATTTATCTTCGGTTCG
CTGGTCGGGCCGAAAATGGACACGCTGTTTGATGGCGCAGGATTTATCTTTGGTTTCAGGGTATTACCGGCAATTATCTT
CGTCACTGCACTGGTGAGTATTCTCTACTACATCGGTGTGATGGGGATTTTAATTCGCATTCTCGGCGGTATATTCCAGA
AAGCATTAAATATCAGCAAGATTGAGTCATTCGTCGCGGTCACCACCATTTTCCTCGGGCAAAACGAAATTCCGGCGATC
GTCAAACCCTTTATCGATCATCTGAATCGCAATGAATTATTTACAGCGATTTGTAGTGGCATGGCCTCGATTGCTGGTTC
GACAATGATTGGTTACGCCGCCCTGGGCGTACCTGTGGAATATTTGCTGGCGGCATCGTTAATGGCGATCCCAGGCGGGA
TCTTGTTTGCCCGCCTGTTAAGCCCGGCTACGGAATCTTCGCAGGTTTCCTTTAATAACCTCTCTTTCACCGAAACACCG
CCAAAAAGCATTATTGAAGCCGCTGCGACAGGGGCAATGACCGGGCTGAAAATCGCCGCCGGTGTAGCGACAGTTGTTAT
GGCAGTCGCCATCATTGCGTTAATTAATGGTATTATCGGCGGCGTTGGCGGCTGGTTTGGTTTTGCACATGCCTCGCTGG
AGTCCATTTTAGGTTACCTGTTGGCCCCATTGGCGTGGGTGATGGGGGTTGACTGGAGTGATGCAAATCTTGCCGGGAGT
TTGATTGGGCAGAAGCTGGCGATCAATGAATTTGTCGCTTATCTCAATTTCTCGCCATATCTGCAAACGGGTGGCACTCT
GGATGCTAAAACCGTGGCGATTATTTCTTTCGCGTTGTGCGGTTTCGCTAACTTTGGTTCTATCGGGGTGGTGGTGGGGG
CGTTTTCTGCGGTTGCGCCACACCGTGCGCCGGAAATCGCCCAACTTGGTTTACGCGCGCTGGCGGCGGCGACACTTTCT
AACCTGATGAGTGCTACTATTGCAGGATTCTTTATTGGTTTAGCGTAG

Upstream 100 bases:

>100_bases
AGTGTTGATAACAAGCCGGGTCAGTATCGCAAGATCCAAGCCCGGCTATTTCTGATGGGCAGAAAGCCGTCGCCCAATAT
GACATGAAGAGATAATAACT

Downstream 100 bases:

>100_bases
TGCGCAATTTATGAGCCGGATAAGATGCGGTCAAGCGTCGAATCCGGCAACATTGTTACACCATTGGCACTAATGAAAGC
GCGTTATCGGCAGACAGGGT

Product: nucleoside transporter, NupC family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MDVMRSVLGMVVLLTIAFLLSVNKKKISLRTVGAALVLQVVIGGIMLWLPAGRWIAEKVAFGVHKVMAYSDAGSAFIFGS
LVGPKMDTLFDGAGFIFGFRVLPAIIFVTALVSILYYIGVMGILIRILGGIFQKALNISKIESFVAVTTIFLGQNEIPAI
VKPFIDHLNRNELFTAICSGMASIAGSTMIGYAALGVPVEYLLAASLMAIPGGILFARLLSPATESSQVSFNNLSFTETP
PKSIIEAAATGAMTGLKIAAGVATVVMAVAIIALINGIIGGVGGWFGFAHASLESILGYLLAPLAWVMGVDWSDANLAGS
LIGQKLAINEFVAYLNFSPYLQTGGTLDAKTVAIISFALCGFANFGSIGVVVGAFSAVAPHRAPEIAQLGLRALAAATLS
NLMSATIAGFFIGLA

Sequences:

>Translated_415_residues
MDVMRSVLGMVVLLTIAFLLSVNKKKISLRTVGAALVLQVVIGGIMLWLPAGRWIAEKVAFGVHKVMAYSDAGSAFIFGS
LVGPKMDTLFDGAGFIFGFRVLPAIIFVTALVSILYYIGVMGILIRILGGIFQKALNISKIESFVAVTTIFLGQNEIPAI
VKPFIDHLNRNELFTAICSGMASIAGSTMIGYAALGVPVEYLLAASLMAIPGGILFARLLSPATESSQVSFNNLSFTETP
PKSIIEAAATGAMTGLKIAAGVATVVMAVAIIALINGIIGGVGGWFGFAHASLESILGYLLAPLAWVMGVDWSDANLAGS
LIGQKLAINEFVAYLNFSPYLQTGGTLDAKTVAIISFALCGFANFGSIGVVVGAFSAVAPHRAPEIAQLGLRALAAATLS
NLMSATIAGFFIGLA
>Mature_415_residues
MDVMRSVLGMVVLLTIAFLLSVNKKKISLRTVGAALVLQVVIGGIMLWLPAGRWIAEKVAFGVHKVMAYSDAGSAFIFGS
LVGPKMDTLFDGAGFIFGFRVLPAIIFVTALVSILYYIGVMGILIRILGGIFQKALNISKIESFVAVTTIFLGQNEIPAI
VKPFIDHLNRNELFTAICSGMASIAGSTMIGYAALGVPVEYLLAASLMAIPGGILFARLLSPATESSQVSFNNLSFTETP
PKSIIEAAATGAMTGLKIAAGVATVVMAVAIIALINGIIGGVGGWFGFAHASLESILGYLLAPLAWVMGVDWSDANLAGS
LIGQKLAINEFVAYLNFSPYLQTGGTLDAKTVAIISFALCGFANFGSIGVVVGAFSAVAPHRAPEIAQLGLRALAAATLS
NLMSATIAGFFIGLA

Specific function: Nucleoside transporter [H]

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI11545853, Length=361, Percent_Identity=35.1800554016621, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI42542381, Length=422, Percent_Identity=30.3317535545024, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI227116277, Length=419, Percent_Identity=30.0715990453461, Blast_Score=202, Evalue=7e-52,
Organism=Escherichia coli, GI1788485, Length=416, Percent_Identity=98.5576923076923, Blast_Score=765, Evalue=0.0,
Organism=Escherichia coli, GI1788488, Length=416, Percent_Identity=87.9807692307692, Blast_Score=690, Evalue=0.0,
Organism=Escherichia coli, GI1788737, Length=414, Percent_Identity=31.6425120772947, Blast_Score=183, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17560276, Length=397, Percent_Identity=30.7304785894207, Blast_Score=201, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI71991794, Length=398, Percent_Identity=32.1608040201005, Blast_Score=195, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI25146537, Length=202, Percent_Identity=30.6930693069307, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI45552519, Length=408, Percent_Identity=32.1078431372549, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI45552517, Length=408, Percent_Identity=32.1078431372549, Blast_Score=222, Evalue=4e-58,
Organism=Drosophila melanogaster, GI19921868, Length=408, Percent_Identity=32.1078431372549, Blast_Score=222, Evalue=4e-58,
Organism=Drosophila melanogaster, GI281360430, Length=407, Percent_Identity=33.1695331695332, Blast_Score=201, Evalue=6e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 43160; Mature: 43160

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVMRSVLGMVVLLTIAFLLSVNKKKISLRTVGAALVLQVVIGGIMLWLPAGRWIAEKVA
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FGVHKVMAYSDAGSAFIFGSLVGPKMDTLFDGAGFIFGFRVLPAIIFVTALVSILYYIGV
HHHHHHHHCCCCCCEEEEHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGILIRILGGIFQKALNISKIESFVAVTTIFLGQNEIPAIVKPFIDHLNRNELFTAICSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHH
MASIAGSTMIGYAALGVPVEYLLAASLMAIPGGILFARLLSPATESSQVSFNNLSFTETP
HHHHHCHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEECCCCCCCCC
PKSIIEAAATGAMTGLKIAAGVATVVMAVAIIALINGIIGGVGGWFGFAHASLESILGYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAPLAWVMGVDWSDANLAGSLIGQKLAINEFVAYLNFSPYLQTGGTLDAKTVAIISFALC
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHH
GFANFGSIGVVVGAFSAVAPHRAPEIAQLGLRALAAATLSNLMSATIAGFFIGLA
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDVMRSVLGMVVLLTIAFLLSVNKKKISLRTVGAALVLQVVIGGIMLWLPAGRWIAEKVA
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FGVHKVMAYSDAGSAFIFGSLVGPKMDTLFDGAGFIFGFRVLPAIIFVTALVSILYYIGV
HHHHHHHHCCCCCCEEEEHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGILIRILGGIFQKALNISKIESFVAVTTIFLGQNEIPAIVKPFIDHLNRNELFTAICSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHH
MASIAGSTMIGYAALGVPVEYLLAASLMAIPGGILFARLLSPATESSQVSFNNLSFTETP
HHHHHCHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEECCCCCCCCC
PKSIIEAAATGAMTGLKIAAGVATVVMAVAIIALINGIIGGVGGWFGFAHASLESILGYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAPLAWVMGVDWSDANLAGSLIGQKLAINEFVAYLNFSPYLQTGGTLDAKTVAIISFALC
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHH
GFANFGSIGVVVGAFSAVAPHRAPEIAQLGLRALAAATLSNLMSATIAGFFIGLA
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]