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The map label for this gene is hipA [H]

Identifier: 187730858

GI number: 187730858

Start: 1608894

End: 1609424

Strand: Reverse

Name: hipA [H]

Synonym: SbBS512_E1765

Alternate gene names: 187730858

Gene position: 1609424-1608894 (Counterclockwise)

Preceding gene: 187732479

Following gene: 187730543

Centisome position: 34.87

GC content: 48.02

Gene sequence:

>531_bases
GTGAAATATGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCGTTTTTGATGGGGTCCAGCGAGGCGCTTCGCGA
TCGTTATGATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGATGGCCATGCAAAAAACTTCTCCGTAT
TTATTCAGGCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGA
ATACACATCAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAATGGCAATCGATAAAATTTATCC
GCGACATTTTTTGGCGACAGCAACGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTAAGTGACTTTGCCAGAA
TGATTCCGGCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAACC
AATGTGTTGAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Upstream 100 bases:

>100_bases
AATAACAACCTTAGCCTGTGGGGGAATGTCGGTGTGCAACTAGGTGATAAAGGCTATAGCGATACTCAGGGCATGCTGGG
AGTGAAATTTACCTTCATCT

Downstream 100 bases:

>100_bases
GATATGGGGTTTGGTCATTGTTAATGAGCAACCATGACCGCCAACGACTGGATTCTCCCTTGGTTTATGTTGGTGCGCAT
AATGTATATTATGTTAAATC

Product: protein HipA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MKYESDGGPGIARIMAFLMGSSEALRDRYDFMKFQVFQWLIGATDGHAKNFSVFIQAGGSYRLTPFYDIISAFPVLGGTG
IHISDLKLAMGLNASKGKKMAIDKIYPRHFLATATVLRFPEVQMHEILSDFARMIPAALDNVKTSLPTDFPENVVTAVET
NVLRLHGRLSREYGSK

Sequences:

>Translated_176_residues
MKYESDGGPGIARIMAFLMGSSEALRDRYDFMKFQVFQWLIGATDGHAKNFSVFIQAGGSYRLTPFYDIISAFPVLGGTG
IHISDLKLAMGLNASKGKKMAIDKIYPRHFLATATVLRFPEVQMHEILSDFARMIPAALDNVKTSLPTDFPENVVTAVET
NVLRLHGRLSREYGSK
>Mature_176_residues
MKYESDGGPGIARIMAFLMGSSEALRDRYDFMKFQVFQWLIGATDGHAKNFSVFIQAGGSYRLTPFYDIISAFPVLGGTG
IHISDLKLAMGLNASKGKKMAIDKIYPRHFLATATVLRFPEVQMHEILSDFARMIPAALDNVKTSLPTDFPENVVTAVET
NVLRLHGRLSREYGSK

Specific function: Unbalanced or excessive expression of hipA is toxic to the cell [H]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To H.influenzae HI_0665 [H]

Homologues:

Organism=Escherichia coli, GI1787785, Length=176, Percent_Identity=97.1590909090909, Blast_Score=357, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 19551; Mature: 19551

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYESDGGPGIARIMAFLMGSSEALRDRYDFMKFQVFQWLIGATDGHAKNFSVFIQAGGS
CCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCC
YRLTPFYDIISAFPVLGGTGIHISDLKLAMGLNASKGKKMAIDKIYPRHFLATATVLRFP
EECCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHCC
EVQMHEILSDFARMIPAALDNVKTSLPTDFPENVVTAVETNVLRLHGRLSREYGSK
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKYESDGGPGIARIMAFLMGSSEALRDRYDFMKFQVFQWLIGATDGHAKNFSVFIQAGGS
CCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCC
YRLTPFYDIISAFPVLGGTGIHISDLKLAMGLNASKGKKMAIDKIYPRHFLATATVLRFP
EECCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHCC
EVQMHEILSDFARMIPAALDNVKTSLPTDFPENVVTAVETNVLRLHGRLSREYGSK
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1715862; 9278503; 8021189 [H]