The gene/protein map for NC_010658 is currently unavailable.
Definition Shigella boydii CDC 3083-94 chromosome, complete genome.
Accession NC_010658
Length 4,615,997

Click here to switch to the map view.

The map label for this gene is xylE [H]

Identifier: 187730615

GI number: 187730615

Start: 4243480

End: 4244274

Strand: Reverse

Name: xylE [H]

Synonym: SbBS512_E4538

Alternate gene names: 187730615

Gene position: 4244274-4243480 (Counterclockwise)

Preceding gene: 187730876

Following gene: 187730394

Centisome position: 91.95

GC content: 52.33

Gene sequence:

>795_bases
ATGTCACGCGGCAAGCAAGAACAGGCGGAAAGTATCCTGCGCAAAATTATGGGCAACACGCTTGCAACTCAGGCAGTACA
GGAAATTAAACACTCCCTGGATCATGGCCGCAAAACCGGTGGTCGTCTGCTGATGTTTGGCGTGGGCGTGATTGTCATCG
GCGTTATGCTCTCCATCTTCCAGCAATTTGTCGGCATCAATGTGGTGCTGTACTACGCGCCGGAAGTGTTCAAAACGCTG
GGGGCCAGCACGGATATCGCGCTGTTGCAGACCATTATTGTCGGAGTTATCAACCTCACCTTCACCGTTCTGGCAATTAT
GACGGTGGATAAATTTGGTCGTAAGCCACTGCAAATTATCGGCGCACTCGGAATGGCAATCGGTATGTTTAGCCTCGGTA
CCGCGTTTTACACTCAGGCACCGGGTATTGTGGCGCTACTGTCGATGCTGTTCTATGTTGCTGCCTTTGCCATGTCCTGG
GGTCCGGTATGCTGGGTACTGCTGTCGGAAATCTTCCCGAATGCTATTCGTGGTAAGGCGCTGGCAATCGCGGTGGCGGC
CCAGTGGCTGGCGAACTACTTCGTCTCCTGGACCTTCCCGATGATGGACAAAAACTCCTGGCTGGTGGCCCATTTCCACA
ACGGTTTCTCCTACTGGATTTACGGGTGTATGGGCGTTCTGGCAGCACTATTTATGTGGAAATTTGTCCCGGAAACCAAA
GGTAAAACCCTTGAGGAGCTGGAAGCCCTCTGGGAACCGGAAACGAAGAAAACACAACAAACTGCTACGCTGTAA

Upstream 100 bases:

>100_bases
AGGACATCTGATGGAAATGGAAGCCACGCAAGCACCTTAAAATCACCATCATACACTAAATCAGTAAGTTGGCAGCATTA
CCGAAAGTCCTCGCTGGCTG

Downstream 100 bases:

>100_bases
TCTTCCTGTCCAGCACGCCGCGCCAGTTCGGCGTGCTGTCTTTTTACTCCCGCTTCAGCCGTTTCGAATTACACAGCCAC
AGAGTGATCACCAGTAACAG

Product: D-xylose-proton symporter

Products: NA

Alternate protein names: D-xylose transporter [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MSRGKQEQAESILRKIMGNTLATQAVQEIKHSLDHGRKTGGRLLMFGVGVIVIGVMLSIFQQFVGINVVLYYAPEVFKTL
GASTDIALLQTIIVGVINLTFTVLAIMTVDKFGRKPLQIIGALGMAIGMFSLGTAFYTQAPGIVALLSMLFYVAAFAMSW
GPVCWVLLSEIFPNAIRGKALAIAVAAQWLANYFVSWTFPMMDKNSWLVAHFHNGFSYWIYGCMGVLAALFMWKFVPETK
GKTLEELEALWEPETKKTQQTATL

Sequences:

>Translated_264_residues
MSRGKQEQAESILRKIMGNTLATQAVQEIKHSLDHGRKTGGRLLMFGVGVIVIGVMLSIFQQFVGINVVLYYAPEVFKTL
GASTDIALLQTIIVGVINLTFTVLAIMTVDKFGRKPLQIIGALGMAIGMFSLGTAFYTQAPGIVALLSMLFYVAAFAMSW
GPVCWVLLSEIFPNAIRGKALAIAVAAQWLANYFVSWTFPMMDKNSWLVAHFHNGFSYWIYGCMGVLAALFMWKFVPETK
GKTLEELEALWEPETKKTQQTATL
>Mature_263_residues
SRGKQEQAESILRKIMGNTLATQAVQEIKHSLDHGRKTGGRLLMFGVGVIVIGVMLSIFQQFVGINVVLYYAPEVFKTLG
ASTDIALLQTIIVGVINLTFTVLAIMTVDKFGRKPLQIIGALGMAIGMFSLGTAFYTQAPGIVALLSMLFYVAAFAMSWG
PVCWVLLSEIFPNAIRGKALAIAVAAQWLANYFVSWTFPMMDKNSWLVAHFHNGFSYWIYGCMGVLAALFMWKFVPETKG
KTLEELEALWEPETKKTQQTATL

Specific function: Uptake of D-xylose across the boundary membrane with the concomitant transport of protons into the cell (symport system) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI23592238, Length=276, Percent_Identity=29.3478260869565, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI5902090, Length=276, Percent_Identity=28.9855072463768, Blast_Score=114, Evalue=7e-26,
Organism=Homo sapiens, GI166795299, Length=259, Percent_Identity=28.5714285714286, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI4557851, Length=268, Percent_Identity=27.6119402985075, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI21361449, Length=226, Percent_Identity=32.7433628318584, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI4507011, Length=222, Percent_Identity=27.4774774774775, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI134053883, Length=266, Percent_Identity=23.3082706766917, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI223029432, Length=292, Percent_Identity=24.6575342465753, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI13540547, Length=104, Percent_Identity=40.3846153846154, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI223029430, Length=263, Percent_Identity=24.3346007604563, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI21553331, Length=108, Percent_Identity=37.962962962963, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI47933387, Length=199, Percent_Identity=23.1155778894472, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI47933389, Length=199, Percent_Identity=23.1155778894472, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI1790463, Length=264, Percent_Identity=99.6212121212121, Blast_Score=536, Evalue=1e-154,
Organism=Escherichia coli, GI1789312, Length=250, Percent_Identity=34.8, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789207, Length=260, Percent_Identity=30.7692307692308, Blast_Score=114, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17534705, Length=267, Percent_Identity=30.7116104868914, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17534703, Length=267, Percent_Identity=30.7116104868914, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI25148667, Length=254, Percent_Identity=31.8897637795276, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17568103, Length=223, Percent_Identity=24.2152466367713, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320007, Length=205, Percent_Identity=32.1951219512195, Blast_Score=116, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6323110, Length=216, Percent_Identity=31.0185185185185, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320766, Length=220, Percent_Identity=28.6363636363636, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324400, Length=220, Percent_Identity=28.6363636363636, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321888, Length=274, Percent_Identity=29.5620437956204, Blast_Score=106, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6320552, Length=274, Percent_Identity=29.1970802919708, Blast_Score=106, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6320549, Length=216, Percent_Identity=29.6296296296296, Blast_Score=105, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6320550, Length=216, Percent_Identity=29.6296296296296, Blast_Score=105, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6322247, Length=215, Percent_Identity=30.6976744186047, Blast_Score=104, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319956, Length=220, Percent_Identity=29.5454545454545, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320063, Length=207, Percent_Identity=31.4009661835749, Blast_Score=103, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6322618, Length=220, Percent_Identity=29.5454545454545, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6324011, Length=208, Percent_Identity=31.25, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6322242, Length=215, Percent_Identity=29.7674418604651, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324417, Length=215, Percent_Identity=29.7674418604651, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321100, Length=220, Percent_Identity=28.6363636363636, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6321886, Length=273, Percent_Identity=27.4725274725275, Blast_Score=98, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323653, Length=213, Percent_Identity=28.6384976525822, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6321884, Length=214, Percent_Identity=28.5046728971963, Blast_Score=92, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6320595, Length=226, Percent_Identity=28.3185840707965, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321068, Length=228, Percent_Identity=25.4385964912281, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324469, Length=217, Percent_Identity=28.110599078341, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320705, Length=217, Percent_Identity=27.6497695852535, Blast_Score=79, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6319718, Length=260, Percent_Identity=25.7692307692308, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321334, Length=180, Percent_Identity=22.2222222222222, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320745, Length=233, Percent_Identity=23.175965665236, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24652793, Length=253, Percent_Identity=31.6205533596838, Blast_Score=134, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24652795, Length=253, Percent_Identity=31.6205533596838, Blast_Score=134, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24652789, Length=205, Percent_Identity=35.609756097561, Blast_Score=128, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24652791, Length=276, Percent_Identity=30.0724637681159, Blast_Score=128, Evalue=5e-30,
Organism=Drosophila melanogaster, GI17737451, Length=256, Percent_Identity=29.296875, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24652312, Length=256, Percent_Identity=29.296875, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24663511, Length=207, Percent_Identity=31.8840579710145, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24663515, Length=255, Percent_Identity=29.4117647058824, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24663519, Length=255, Percent_Identity=29.4117647058824, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI20130083, Length=257, Percent_Identity=29.1828793774319, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI161080353, Length=258, Percent_Identity=26.3565891472868, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI161078056, Length=262, Percent_Identity=28.6259541984733, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21357295, Length=262, Percent_Identity=28.6259541984733, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24654932, Length=263, Percent_Identity=25.8555133079848, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI17737517, Length=263, Percent_Identity=25.8555133079848, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI161080349, Length=258, Percent_Identity=26.7441860465116, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI161080351, Length=270, Percent_Identity=25.9259259259259, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24644448, Length=223, Percent_Identity=26.9058295964126, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24644446, Length=223, Percent_Identity=26.9058295964126, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17933702, Length=197, Percent_Identity=24.3654822335025, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24640302, Length=271, Percent_Identity=27.6752767527675, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24640300, Length=271, Percent_Identity=27.6752767527675, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI45552195, Length=207, Percent_Identity=29.951690821256, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17864324, Length=263, Percent_Identity=24.3346007604563, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24653937, Length=226, Percent_Identity=26.1061946902655, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17647965, Length=194, Percent_Identity=24.7422680412371, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24585912, Length=261, Percent_Identity=22.2222222222222, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24585914, Length=261, Percent_Identity=22.2222222222222, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161076658, Length=210, Percent_Identity=25.7142857142857, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR003663
- InterPro:   IPR005829 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 29160; Mature: 29029

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure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CCHHHHHHHHHCCCHHHHHHHCCC
>Mature Secondary Structure 
SRGKQEQAESILRKIMGNTLATQAVQEIKHSLDHGRKTGGRLLMFGVGVIVIGVMLSIF
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
QQFVGINVVLYYAPEVFKTLGASTDIALLQTIIVGVINLTFTVLAIMTVDKFGRKPLQII
HHHHHHHHHEEECHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
GALGMAIGMFSLGTAFYTQAPGIVALLSMLFYVAAFAMSWGPVCWVLLSEIFPNAIRGKA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHH
LAIAVAAQWLANYFVSWTFPMMDKNSWLVAHFHNGFSYWIYGCMGVLAALFMWKFVPETK
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCC
GKTLEELEALWEPETKKTQQTATL
CCHHHHHHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]