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The map label for this gene is adrA

Identifier: 187730193

GI number: 187730193

Start: 295865

End: 296965

Strand: Direct

Name: adrA

Synonym: SbBS512_E0302

Alternate gene names: 187730193

Gene position: 295865-296965 (Clockwise)

Preceding gene: 187733634

Following gene: 187730855

Centisome position: 6.41

GC content: 53.59

Gene sequence:

>1101_bases
ATGTTCCCAAAAATAATGAATGATGAAAACTTTTTCAAAAAAGCGGCGGCGCATGGGGAGGAACCTCCTTTAACTCCTCA
AAACGAACATCAGCGGTCCGGGCTGCGCTTCGCCCGTCGCGTCAGACTACCCCGTGCGGTTGGCCTGGCTGGCATGTTCT
TACCGATTGCTTCAACGCTGGTTTCGCACCCGCCGCCGGGCTGGTGGTGGCTGGTGTTGGTCTGGCCGCATTTAGCCTGG
CAGATAGCGAGCAGGGCCGTCGATCCGCTTAGCCGGGAAATTTACAACTTAAAAACCGATGCAGTATTAGCGGGAATGTG
GGTAGGCGTAATGGGCGTAAACGTGCTGCCTTCCACCGCTATGTTGATGATTATGTGTCTGAATTTGATGGGGGCAGGCG
GCCCCCGTCTGTTTGTCGCGGGTCTGGTGTTGATGGTGGTTTCCTGCCTTGTCACCCTCGAGCTTACGGGCATTACCGTG
TCGTTCAATAGTGCGCCGCTGGAATGGTGGCTCTCCCTTCCCATTATTGTCGTTTATCCTCTGCTGTTTGGCTGGGTCAG
CTACCAGACGGCAACCAAACTGGCGGAACATAAACGCAGGTTGCAGGTCATGAGTACCCGCGACGGCATGACGGGCGTGT
ATAACCGACGTCATTGGGAAACTATGTTACGCAATGAATTTGATAACTGTCGGCGGCATAATCGCGATGCAACGTTACTG
ATTATCGATATCGACCATTTCAAGAGCATCAACGATACCTGGGGTCATGATGTGGGCGATGAAGCGATTGTGGCGCTTAC
CCGACAGTTACAAATTACCCTGCGCGGTAGCGATGTGATTGGTCGGTTTGGCGGCGATGAGTTTGCAGTAATCATGTCCG
GTACGCCAGCTGAGAGCGCCATTACCGCCATGTTACGGGTGCGTGAAGGGCTAAACACGTTACGCTTGCCGAATACGCCA
CAGGTAACTTTACGGATTAGTGTGGGGGTTGCGCCGCTGAACCCACAAATGAGTCACTATCGTGAGTGGTTGAAATCGGC
AGATTTGGCGCTTTACAAAGCAAAGAAAGCCGGACGTAACCGCACCGAAGTGGCGGCCTGA

Upstream 100 bases:

>100_bases
ACCTGATAGTGCTAACGGGTGAGCTACGAAAGTGGCTCACCCGAAATTTCATACTTCTGCCTTTAGCCCCGTCTCTATAA
TTTGGGAAAATTGTTTCTGA

Downstream 100 bases:

>100_bases
CGTCCGGCGAAAGTCATCAGGATTTGCTGAGTTTTTCTGATTTTTCCATACACTTCGTCATCGCTTCGATCACTGCGGCA
CGGAAGCCTTTCTCTTCCAG

Product: diguanylate cyclase AdrA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MFPKIMNDENFFKKAAAHGEEPPLTPQNEHQRSGLRFARRVRLPRAVGLAGMFLPIASTLVSHPPPGWWWLVLVWPHLAW
QIASRAVDPLSREIYNLKTDAVLAGMWVGVMGVNVLPSTAMLMIMCLNLMGAGGPRLFVAGLVLMVVSCLVTLELTGITV
SFNSAPLEWWLSLPIIVVYPLLFGWVSYQTATKLAEHKRRLQVMSTRDGMTGVYNRRHWETMLRNEFDNCRRHNRDATLL
IIDIDHFKSINDTWGHDVGDEAIVALTRQLQITLRGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVREGLNTLRLPNTP
QVTLRISVGVAPLNPQMSHYREWLKSADLALYKAKKAGRNRTEVAA

Sequences:

>Translated_366_residues
MFPKIMNDENFFKKAAAHGEEPPLTPQNEHQRSGLRFARRVRLPRAVGLAGMFLPIASTLVSHPPPGWWWLVLVWPHLAW
QIASRAVDPLSREIYNLKTDAVLAGMWVGVMGVNVLPSTAMLMIMCLNLMGAGGPRLFVAGLVLMVVSCLVTLELTGITV
SFNSAPLEWWLSLPIIVVYPLLFGWVSYQTATKLAEHKRRLQVMSTRDGMTGVYNRRHWETMLRNEFDNCRRHNRDATLL
IIDIDHFKSINDTWGHDVGDEAIVALTRQLQITLRGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVREGLNTLRLPNTP
QVTLRISVGVAPLNPQMSHYREWLKSADLALYKAKKAGRNRTEVAA
>Mature_366_residues
MFPKIMNDENFFKKAAAHGEEPPLTPQNEHQRSGLRFARRVRLPRAVGLAGMFLPIASTLVSHPPPGWWWLVLVWPHLAW
QIASRAVDPLSREIYNLKTDAVLAGMWVGVMGVNVLPSTAMLMIMCLNLMGAGGPRLFVAGLVLMVVSCLVTLELTGITV
SFNSAPLEWWLSLPIIVVYPLLFGWVSYQTATKLAEHKRRLQVMSTRDGMTGVYNRRHWETMLRNEFDNCRRHNRDATLL
IIDIDHFKSINDTWGHDVGDEAIVALTRQLQITLRGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVREGLNTLRLPNTP
QVTLRISVGVAPLNPQMSHYREWLKSADLALYKAKKAGRNRTEVAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=371, Percent_Identity=98.1132075471698, Blast_Score=741, Evalue=0.0,
Organism=Escherichia coli, GI145693134, Length=159, Percent_Identity=35.2201257861635, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI87081881, Length=171, Percent_Identity=35.672514619883, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787262, Length=165, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082007, Length=164, Percent_Identity=36.5853658536585, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1788381, Length=177, Percent_Identity=29.9435028248588, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787802, Length=163, Percent_Identity=31.2883435582822, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787541, Length=178, Percent_Identity=30.8988764044944, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI87081977, Length=167, Percent_Identity=32.3353293413174, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI87081974, Length=155, Percent_Identity=29.6774193548387, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788085, Length=180, Percent_Identity=28.3333333333333, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1787816, Length=165, Percent_Identity=29.6969696969697, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787056, Length=147, Percent_Identity=36.0544217687075, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788956, Length=150, Percent_Identity=30, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 40982; Mature: 40982

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPKIMNDENFFKKAAAHGEEPPLTPQNEHQRSGLRFARRVRLPRAVGLAGMFLPIASTL
CCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VSHPPPGWWWLVLVWPHLAWQIASRAVDPLSREIYNLKTDAVLAGMWVGVMGVNVLPSTA
HCCCCCCCEEEHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHH
MLMIMCLNLMGAGGPRLFVAGLVLMVVSCLVTLELTGITVSFNSAPLEWWLSLPIIVVYP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHHH
LLFGWVSYQTATKLAEHKRRLQVMSTRDGMTGVYNRRHWETMLRNEFDNCRRHNRDATLL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
IIDIDHFKSINDTWGHDVGDEAIVALTRQLQITLRGSDVIGRFGGDEFAVIMSGTPAESA
EEEHHHCCCCCCCCCCCCCCHHHHHHHHHEEEEEECCCEEECCCCCEEEEEEECCCHHHH
ITAMLRVREGLNTLRLPNTPQVTLRISVGVAPLNPQMSHYREWLKSADLALYKAKKAGRN
HHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHCCCC
RTEVAA
CCCCCC
>Mature Secondary Structure
MFPKIMNDENFFKKAAAHGEEPPLTPQNEHQRSGLRFARRVRLPRAVGLAGMFLPIASTL
CCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VSHPPPGWWWLVLVWPHLAWQIASRAVDPLSREIYNLKTDAVLAGMWVGVMGVNVLPSTA
HCCCCCCCEEEHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHH
MLMIMCLNLMGAGGPRLFVAGLVLMVVSCLVTLELTGITVSFNSAPLEWWLSLPIIVVYP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHHH
LLFGWVSYQTATKLAEHKRRLQVMSTRDGMTGVYNRRHWETMLRNEFDNCRRHNRDATLL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
IIDIDHFKSINDTWGHDVGDEAIVALTRQLQITLRGSDVIGRFGGDEFAVIMSGTPAESA
EEEHHHCCCCCCCCCCCCCCHHHHHHHHHEEEEEECCCEEECCCCCEEEEEEECCCHHHH
ITAMLRVREGLNTLRLPNTPQVTLRISVGVAPLNPQMSHYREWLKSADLALYKAKKAGRN
HHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHCCCC
RTEVAA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]