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The map label for this gene is prlC [H]

Identifier: 187736643

GI number: 187736643

Start: 2642583

End: 2644685

Strand: Reverse

Name: prlC [H]

Synonym: Amuc_2167

Alternate gene names: 187736643

Gene position: 2644685-2642583 (Counterclockwise)

Preceding gene: 187736644

Following gene: 187736642

Centisome position: 99.27

GC content: 59.77

Gene sequence:

>2103_bases
ATGAACCATCCCTATCTGGACCCCTCCTTTCTGGTTTCCTGGTCCCGGCTTACGCCGGAGGCCATCAGGCCGGACATCAC
GGAAGCCATCTCCCGCGCCAAAGAGAATATCCGGACCATTTGCGACCAGCCGCTGGAGTCCCTGACTTATGAAAGCACCT
TCGGCGCTCTGGAAAAGGCCTCCGAGGATCTGCACCTGGGCTGGGGCCGCATCATGCACCTGGACTCCGTCAATGACGAA
CCCGCCCAGAGGGAGGCCATCGGGGAAATGCTGCCGGAAGTGGTGGCTTTCTCCTCCTCCGTGCCGTTGAACCCGCGCCT
GTGGACGGTGCTGAAAGCCGCGGCCTCCTGTGACTGGGTGAAAAGCCTTTCCCCCGTCAGGCAGCGTTTCATCCAGGAAA
CGCTGGCGGACTTCCGCGAGAGCGGGGCGGACCTGCCGGACGACGTGAAGCCGGAATATGCGGAGATAGAAGCCCAGCTC
TCCCTGAAGACCAAGAAATTCGCGGAAAACGTGCTGGACTCCACCAACGCCTGGGAACTCATTGTGGAAGATGAAGCGGA
ACTTTCCGGGCTGCCGGATTCCGCGAAGGAAGCCGCCCGCCTGGATGCCCTGGCCAACGGCCACGGCACGGAAGAAGCCC
CCCGCTGGCGCTTCACCCAGAAATTTACCTCCCTCCAGCCTGTCATGCAGTTTGCGGACTCGGACAGCCTGCGCCGCCGC
ATGTGGGAGGGCTCCTGTTCCATCGGGAAGGGCGGAGAATACGATAATGAAGCCCTTATCGCTGAAATCCTGGAACTGAG
GGACAGGAAAGCCCATTTGCTGGGGTACGGCTGCTTTGCGGATTACGCCACTTCCCGCCGCATGGCCGGGAGCGGAGCCA
ACGCCCTGAAATTCATCAACGACCTGCATGACAGGGTGAAGCCCTCTTTCCTGAAGGACATGGAAGCCGTTCGCAGGTAC
AAGGAGGAAAAAACAGGAAAACCCGTGGAAAAGCTCTCCCCGTGGGAAACCGGATACTGGTCTGAAAAACGCCGCCGCGA
ATTGTACGCTTTTGACGAGGAAGACCTGCGCCCGTATTACTCCGTGGAAAAAGTCATGGAAGGGCTCTTTTCCATCTACT
CCGGCCTGTACGGCATCACGGTCACGCCGCGTCCCACGGTGGCGTTCAAGCCCGGTGAATCCGGGGAAGCGCCGGAAGGC
GCGGTGGAGGTGTGGCATCCGGACGTCCTGTTCTATGAATTGCATGATGCGGAAAGCGGGGAACACCTGGGTTCCTTTTA
TGCGGACTGGCATCCGAGGGACTCCAAGCGCGCCGGAGCGTGGATGAACTACCTGAGCGTAGGGGAACCTCCGCACGGCG
GAAAACCCCGCGTTCCCCATCTGGGTCTCATGGTCGGCAACATGACCAAGCCCGTAGGGGACAAGCCCGCGCTGCTGTCC
CACCGGGAGGTGGAAACCATCTTCCATGAATTCGGCCACCTGCTGCACCAGCTCCTTTCCGATGTGGAAGTGAAGTCCCT
GTCGGGCACCAACGTTGCCTGGGACTTTGTGGAACTGCCCTCCCAGATTAATGAAAACTGGTGTTGGGAGCGTGAATCCG
TGGACCTCTTCGCCGCCCACTATGAAACGGGTGAAAAAATACCGGACGAACTGTTCTCCAAAATGCGCGCCGCCCGCAAT
TATATGAGCGGCACGGATTTCATGCGCCAGCTCTGCTTTGGCAAGCTGGATCTGGAGCTTCACGTAAACTGGCCTCAGTA
CAAGGGTGTTCCGCTGGAAGAAACGGATGAACGCATTCTGGCGGATTACCGGGTGCCGATGACGGACCGCGGCCCTTCCG
TGGCGCGCCGCCTGACCCACATCTTCGCGGATCCCACGGGTTATGCTTCCGGTTATTACTCCTACAAATGGGCGGAGGTG
CTGGAAGCGGACGCTTTCAGCCGCTTCCTGAAAGAAGGAGTGCTGAATCCCCGAACCGGGCGCGACTTCCGCCGCTGCAT
CCTCAGCAAGGGCAACAGCAAGCCTGCCGCTGAACTCTACCGCGACTTCATGGGCCGTGATCCGGACGCGGAAGCGCTGC
TTGTCAAATCCGGCGTTCTTTAA

Upstream 100 bases:

>100_bases
ATGTTCCTTAAACATGGTAAGTTTTATTTTTTCATGGCTGTTGCGGCAAATACCGGAACGCGTCCGTTGTCATTTTCAAT
AACATCATACATCAAGCAAT

Downstream 100 bases:

>100_bases
CCTCTCTACCCATATTATCTGCACAATCCTTATGCCTGAACAAAAGAGACTCTCCCTCGCCGGTATCGGGTGCGGTTCCC
GTACGCGCACCTACATGAAG

Product: Oligopeptidase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 700; Mature: 700

Protein sequence:

>700_residues
MNHPYLDPSFLVSWSRLTPEAIRPDITEAISRAKENIRTICDQPLESLTYESTFGALEKASEDLHLGWGRIMHLDSVNDE
PAQREAIGEMLPEVVAFSSSVPLNPRLWTVLKAAASCDWVKSLSPVRQRFIQETLADFRESGADLPDDVKPEYAEIEAQL
SLKTKKFAENVLDSTNAWELIVEDEAELSGLPDSAKEAARLDALANGHGTEEAPRWRFTQKFTSLQPVMQFADSDSLRRR
MWEGSCSIGKGGEYDNEALIAEILELRDRKAHLLGYGCFADYATSRRMAGSGANALKFINDLHDRVKPSFLKDMEAVRRY
KEEKTGKPVEKLSPWETGYWSEKRRRELYAFDEEDLRPYYSVEKVMEGLFSIYSGLYGITVTPRPTVAFKPGESGEAPEG
AVEVWHPDVLFYELHDAESGEHLGSFYADWHPRDSKRAGAWMNYLSVGEPPHGGKPRVPHLGLMVGNMTKPVGDKPALLS
HREVETIFHEFGHLLHQLLSDVEVKSLSGTNVAWDFVELPSQINENWCWERESVDLFAAHYETGEKIPDELFSKMRAARN
YMSGTDFMRQLCFGKLDLELHVNWPQYKGVPLEETDERILADYRVPMTDRGPSVARRLTHIFADPTGYASGYYSYKWAEV
LEADAFSRFLKEGVLNPRTGRDFRRCILSKGNSKPAAELYRDFMGRDPDAEALLVKSGVL

Sequences:

>Translated_700_residues
MNHPYLDPSFLVSWSRLTPEAIRPDITEAISRAKENIRTICDQPLESLTYESTFGALEKASEDLHLGWGRIMHLDSVNDE
PAQREAIGEMLPEVVAFSSSVPLNPRLWTVLKAAASCDWVKSLSPVRQRFIQETLADFRESGADLPDDVKPEYAEIEAQL
SLKTKKFAENVLDSTNAWELIVEDEAELSGLPDSAKEAARLDALANGHGTEEAPRWRFTQKFTSLQPVMQFADSDSLRRR
MWEGSCSIGKGGEYDNEALIAEILELRDRKAHLLGYGCFADYATSRRMAGSGANALKFINDLHDRVKPSFLKDMEAVRRY
KEEKTGKPVEKLSPWETGYWSEKRRRELYAFDEEDLRPYYSVEKVMEGLFSIYSGLYGITVTPRPTVAFKPGESGEAPEG
AVEVWHPDVLFYELHDAESGEHLGSFYADWHPRDSKRAGAWMNYLSVGEPPHGGKPRVPHLGLMVGNMTKPVGDKPALLS
HREVETIFHEFGHLLHQLLSDVEVKSLSGTNVAWDFVELPSQINENWCWERESVDLFAAHYETGEKIPDELFSKMRAARN
YMSGTDFMRQLCFGKLDLELHVNWPQYKGVPLEETDERILADYRVPMTDRGPSVARRLTHIFADPTGYASGYYSYKWAEV
LEADAFSRFLKEGVLNPRTGRDFRRCILSKGNSKPAAELYRDFMGRDPDAEALLVKSGVL
>Mature_700_residues
MNHPYLDPSFLVSWSRLTPEAIRPDITEAISRAKENIRTICDQPLESLTYESTFGALEKASEDLHLGWGRIMHLDSVNDE
PAQREAIGEMLPEVVAFSSSVPLNPRLWTVLKAAASCDWVKSLSPVRQRFIQETLADFRESGADLPDDVKPEYAEIEAQL
SLKTKKFAENVLDSTNAWELIVEDEAELSGLPDSAKEAARLDALANGHGTEEAPRWRFTQKFTSLQPVMQFADSDSLRRR
MWEGSCSIGKGGEYDNEALIAEILELRDRKAHLLGYGCFADYATSRRMAGSGANALKFINDLHDRVKPSFLKDMEAVRRY
KEEKTGKPVEKLSPWETGYWSEKRRRELYAFDEEDLRPYYSVEKVMEGLFSIYSGLYGITVTPRPTVAFKPGESGEAPEG
AVEVWHPDVLFYELHDAESGEHLGSFYADWHPRDSKRAGAWMNYLSVGEPPHGGKPRVPHLGLMVGNMTKPVGDKPALLS
HREVETIFHEFGHLLHQLLSDVEVKSLSGTNVAWDFVELPSQINENWCWERESVDLFAAHYETGEKIPDELFSKMRAARN
YMSGTDFMRQLCFGKLDLELHVNWPQYKGVPLEETDERILADYRVPMTDRGPSVARRLTHIFADPTGYASGYYSYKWAEV
LEADAFSRFLKEGVLNPRTGRDFRRCILSKGNSKPAAELYRDFMGRDPDAEALLVKSGVL

Specific function: May play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins. Can cleave N-acetyl-L-Ala(4) [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=689, Percent_Identity=30.6240928882438, Blast_Score=302, Evalue=7e-82,
Organism=Homo sapiens, GI14149738, Length=690, Percent_Identity=28.695652173913, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI156105687, Length=617, Percent_Identity=25.1215559157212, Blast_Score=151, Evalue=2e-36,
Organism=Escherichia coli, GI1789913, Length=708, Percent_Identity=36.7231638418079, Blast_Score=435, Evalue=1e-123,
Organism=Escherichia coli, GI1787819, Length=703, Percent_Identity=27.7382645803698, Blast_Score=239, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI71999758, Length=593, Percent_Identity=22.5969645868465, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI32565901, Length=596, Percent_Identity=20.8053691275168, Blast_Score=92, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6319793, Length=582, Percent_Identity=27.6632302405498, Blast_Score=238, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6322715, Length=681, Percent_Identity=21.1453744493392, Blast_Score=118, Evalue=4e-27,
Organism=Drosophila melanogaster, GI21356111, Length=716, Percent_Identity=24.8603351955307, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI20129717, Length=421, Percent_Identity=25.41567695962, Blast_Score=152, Evalue=9e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.24.70 [H]

Molecular weight: Translated: 79326; Mature: 79326

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHPYLDPSFLVSWSRLTPEAIRPDITEAISRAKENIRTICDQPLESLTYESTFGALEKA
CCCCCCCHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SEDLHLGWGRIMHLDSVNDEPAQREAIGEMLPEVVAFSSSVPLNPRLWTVLKAAASCDWV
CCHHCCCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
KSLSPVRQRFIQETLADFRESGADLPDDVKPEYAEIEAQLSLKTKKFAENVLDSTNAWEL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
IVEDEAELSGLPDSAKEAARLDALANGHGTEEAPRWRFTQKFTSLQPVMQFADSDSLRRR
EEECCHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHH
MWEGSCSIGKGGEYDNEALIAEILELRDRKAHLLGYGCFADYATSRRMAGSGANALKFIN
HHCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHEEEHHHHHHHHHHHHCCCCCHHHHHHH
DLHDRVKPSFLKDMEAVRRYKEEKTGKPVEKLSPWETGYWSEKRRRELYAFDEEDLRPYY
HHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHCCCCHHHCCHHH
SVEKVMEGLFSIYSGLYGITVTPRPTVAFKPGESGEAPEGAVEVWHPDVLFYELHDAESG
HHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCCCCCCCCCEEEECCCEEEEEECCCCCC
EHLGSFYADWHPRDSKRAGAWMNYLSVGEPPHGGKPRVPHLGLMVGNMTKPVGDKPALLS
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHEEECCCCCCCCCCCCHHH
HREVETIFHEFGHLLHQLLSDVEVKSLSGTNVAWDFVELPSQINENWCWERESVDLFAAH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHH
YETGEKIPDELFSKMRAARNYMSGTDFMRQLCFGKLDLELHVNWPQYKGVPLEETDERIL
HHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHH
ADYRVPMTDRGPSVARRLTHIFADPTGYASGYYSYKWAEVLEADAFSRFLKEGVLNPRTG
HHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
RDFRRCILSKGNSKPAAELYRDFMGRDPDAEALLVKSGVL
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEECCCCCC
>Mature Secondary Structure
MNHPYLDPSFLVSWSRLTPEAIRPDITEAISRAKENIRTICDQPLESLTYESTFGALEKA
CCCCCCCHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SEDLHLGWGRIMHLDSVNDEPAQREAIGEMLPEVVAFSSSVPLNPRLWTVLKAAASCDWV
CCHHCCCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
KSLSPVRQRFIQETLADFRESGADLPDDVKPEYAEIEAQLSLKTKKFAENVLDSTNAWEL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
IVEDEAELSGLPDSAKEAARLDALANGHGTEEAPRWRFTQKFTSLQPVMQFADSDSLRRR
EEECCHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHH
MWEGSCSIGKGGEYDNEALIAEILELRDRKAHLLGYGCFADYATSRRMAGSGANALKFIN
HHCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHEEEHHHHHHHHHHHHCCCCCHHHHHHH
DLHDRVKPSFLKDMEAVRRYKEEKTGKPVEKLSPWETGYWSEKRRRELYAFDEEDLRPYY
HHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHCCCCHHHCCHHH
SVEKVMEGLFSIYSGLYGITVTPRPTVAFKPGESGEAPEGAVEVWHPDVLFYELHDAESG
HHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCCCCCCCCCEEEECCCEEEEEECCCCCC
EHLGSFYADWHPRDSKRAGAWMNYLSVGEPPHGGKPRVPHLGLMVGNMTKPVGDKPALLS
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHEEECCCCCCCCCCCCHHH
HREVETIFHEFGHLLHQLLSDVEVKSLSGTNVAWDFVELPSQINENWCWERESVDLFAAH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHH
YETGEKIPDELFSKMRAARNYMSGTDFMRQLCFGKLDLELHVNWPQYKGVPLEETDERIL
HHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHH
ADYRVPMTDRGPSVARRLTHIFADPTGYASGYYSYKWAEVLEADAFSRFLKEGVLNPRTG
HHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
RDFRRCILSKGNSKPAAELYRDFMGRDPDAEALLVKSGVL
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]