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The map label for this gene is rocA [H]

Identifier: 187736545

GI number: 187736545

Start: 2509841

End: 2513422

Strand: Reverse

Name: rocA [H]

Synonym: Amuc_2066

Alternate gene names: 187736545

Gene position: 2513422-2509841 (Counterclockwise)

Preceding gene: 187736546

Following gene: 187736544

Centisome position: 94.34

GC content: 57.23

Gene sequence:

>3582_bases
ATGACAGATTCATCCATCCCGGACATGATGGCGGAGGCTCGCCGAGGCCAATGGACTGACCAGCAACTGGCCGCCAAGGC
TGTGGAACTGGCGGAGTCCATTTTAAAGCAGTCGAATGCCGGGATGAGAGGGAAAGAGAAGAGGCAGGCGCAGCAAATGG
AGCGCATGATGAATGATCCGGCGGGCAAGGCGTTTACGCTGGCACTGGCGGATCGTGTGTTCCGTCCTTCTTCTCCGGTG
CGGGGTGCTGAGTTGTTCCGCTATCTTTTGGACGGATATGGCGTTCCCCGTTATTTGTCTGCGGCGGACCGTTTCGCCAT
AAAAATGGGGGGGAGGTTTTCCGCTCAATTTCCGGGTGTGGTCATGCCCGTGATTACCAGCCAGTTGAGAAAGGAGAGCT
CCAATGTAATTCTTCCTGCCGAGGATGGAAAACTGCGCCCCCACCTGCGCCGCAGGCGCAAGGGCGGCATCCGGATGAAT
ATCAACCAGCTGGGAGAGGCCATTCTGGGTGAAAGCGAGGCGCACCACCGTCTTCAGCAGGTCGTGGACCGGCTGACAGA
CAAGGACTGTGACTATATTTCCGTCAAGATTTCAGCCATTTTCAGCCAGATTCATCTGGTAGCCTTTGAAGAAACCGTCA
AATTGATTCAGGAGCGCCTGCGCATCCTGTACCGGGCGGCCATTACCAATGCGGTAACGTTGCCGGACGGTTCCAGAAAG
CCCAAGTTCGTGAATCTGGATATGGAGGAATACCGTGATCTTCATCTGACGGCGGAAGCGTTCAAACGTACGTTGATGGA
GGATGAATTCATGCAGCTGGAGGCGGGGATTGTGCTCCAGGCCTATTTGCCGGATTCCTGGGAGGAGCAGATGAAGCTGT
GCGCCTGGGCGAAGGAACGCGTGGAGCAGGGGGGGGCGCGCATCAAAATACGCCTGGTGAAAGGCGCCAACCTGGCGATG
GAGAAGGTGGAGGCCTCCATGCATGGCTGGGCGCAGGCCCCGTATGGCACGAAAGCCCAGGTGGATGCCAATTACAAGAG
AATGCTCCATTACGGCTGCATGCCGGATAATGCCAGATATGTGCAGTTCGGCGTAGCTTCCCACAACCTGTTTGATTTGT
GTTATGCCATGCTGCTGCGTGAGCGGGAAGGCGTGCGTGACCAGGTGGAATTCGAAATGCTGGAAGGGATGGCGAACCAT
CAGGCGCGGGTCATCCGCCAGGCGGCGGACGGTCTGCTCCTTTATGCCCCTGTGGTTTTGAAGGAAGATTTTCACAGCGC
TATTGCCTACCTGGTCCGGAGACTGGATGAAAATACCAGTGAGGAGAACTTCCTGCATGATCTCTTCGGTATGACACCGG
GGTCCCGGAGCTGGGAGGTCCAGAAAAAGAGGTTTTTGAAGGCTTGTCAGGAAAAGGATGAGGTGAAGTACGGCCCCAAC
CGCACGCAGAACCGCGCTGCGGATCCCATCCAGCCCTCACATTACCGGGACGCCTTTGCCAACGAGCGGGATACGGACTG
GTCCCTGCGGCAGAATGCGGAATGGATCAACGGGCTGATTGCCGCGGAGAAGGAAAAATCCGGCGAGGAAATCCCTCTGG
TTATAGATGGTGAGGAAATTACGACTAATCTATGGGGCGTGGGGCGCGATCCGTCCCGCCATAATGAAGTTTCCTATAAA
TTCGCTTATGCGGATTTTGACCAGGTTGAACATGCCTTGGTCACGGCAGACAGGGTCCGCTCCTCCTGGGCGTCCAAAAG
CATTGGCGAACGCGCTGAAATCCTGCACCGGGCGGCGCAGGAGCTGTCCAGAATCAGGGGGGAAGCCATTGCTGCCATGG
TGAGGGATGCCGGGAAAGCTCCCACGGAGGCTGATGTGGAGGTGAGCGAGGCCATAGACTTCTGCCGCTATTACGCGGAA
GGCTTGGACCGCGACGGAATGAACGACGGCGTGGAAATGTCCCCGCTGGGTATCATTTGCGTGATGTCTCCCTGGAATTT
CCCCTTCGCCATTCCGACGGGCGGTGTAGCTGCCGCCCTGATGGCGGGAAATGCCGTGGTGTTCAAACCGTCCGAACTGG
CCGTTTATACGGCTTGGCAGATTGTCCAGGCGTTCTGGCGTGCCGGTGTGCCTAAAAACGTCCTTCAATTCGTGCCGATG
CCGCGCAATGAAATTTCCTGCAAGTTTCTGATGGATCCCCGTTTGAACGGTGTGATCATGACGGGATCCTACCGCACCGG
AAAAATGCTGCGCGAACTGCGGCCTGACCTGCATGTGCTGGCTGAAACCAGCGGAAAGGATGCCATGATCATCACTGCTA
CGGCTGATCCGGACCAGGCTGTAAAGGATTTGGTGAAAAGCGCTTTCGGTCATTCCGGACAGAAGTGTTCCGCCGCCAGC
GTGGCTATTGTGGAGGCTTCCGTTTATGACAATCCCGCCTTTTTGCGTCAGTTGAAGGATGCCGCCGCCAGCCTGAAGGT
AGGCGGATCCTGGGAAGTCAACTCCGTGGTGACGCCGCTCATCAGGGAGCCGGAAGGGAATCTGCTCCGTGCGCTGACGC
AGCTGGAACCCGGGGAGGAATGGCTGCTCAAGCCGGAACCTTCGGAAGACAACCCGTGCCTCTGGTCTCCCGGCATCCGG
CTGGGGGTGAAACCGGGAAGCTGGTTCCATCAGACGGAATGCTTCGGTCCGGTATTGGGAATCATCCGTGCGGAAAACCT
GGAGGAAGCCATTGACATCCAAAACGACTCCGAATTTGGCCTTACCGGCGGCCTTCAGTCCCTGGATGAACGGGAAATTG
CCTTGTGGAAAACTAAAGTGCAGGTGGGCAACGCGTACATCAACCGTGTCATCACCGGCGCCATTGTCCGCCGCCAGCCG
TTCGGCGGGTGGAACCATTCCTCCATGGGGCCTGGAGCCAAGGCCGGAGGTCCCAACTACCTTACCATGCTGGGAAGTTG
GGAGGAAAAGGCGCTGCCCCAAAAGCTGCGCACGCCGGGTGAACGTATCTCCGGACTGGTGGAAAAACTGTGTTCCGAGC
TGCCGGACTGCGCCAAGCGCATCCGTTCCGCAGCTGGTTCCCAGGCCAAGTGGTGGATGGAGGAATTCGGCGTGGATCAT
GATCCCTCCCGTGTTTACGGAGAAAATAATACCTTCCGCTATATCCCGGTGAAGGGAATTCTGGCCCGTGTGGAAAACAT
GTCCGACGATGACGTCGCCATTCTGCTGCTGGGGGCGAAACTGTGCGGGGTACTCCTGCACCTGAGCATAGGGACGAGCC
GCCCCTGGATTCAGAAAATGCATGGTTATTATGCTTCCCTGACGGTGGAAACGGAAGCGGAATTGATCGGACGGATGCCG
GAAGCCCTTCCAGGCATACGGTTCCTGCGTGGAACAGATATTTCCGAGACTCTGGCCAATGCCGCCCGTGCCCGGGATGT
GGAAGTACTGGACCGTCCCGTGCTTGCCAATGGACGGTTGGAACTGCTGGGGTATTTCCGGGAACAGTCTGTTTCCGAAA
CCGTTCACCGCTATGGCAATCTCATCCCGCCACCAGGCAGTTTTAAAACAGACAGCGTGTGA

Upstream 100 bases:

>100_bases
ATCAAGGGATGCGTTTTCCTCCGTGATTCCTCTTTCCACAGGAAGGACCGGGCAAATTGGCTTGATTTTGCCCCTGTCCG
GGGCTAGTCTTCGAACCGTT

Downstream 100 bases:

>100_bases
AGGGTAGGGAAGGCCTGAATCCCGGCTTCCGGGTATCTTAGCCATAAAAATGAAGGGAAATCCTCCTGCCGGTCCAAAAG
GAAAACATGGGTGTTGAGTG

Product: Aldehyde Dehydrogenase

Products: NA

Alternate protein names: P5C dehydrogenase [H]

Number of amino acids: Translated: 1193; Mature: 1192

Protein sequence:

>1193_residues
MTDSSIPDMMAEARRGQWTDQQLAAKAVELAESILKQSNAGMRGKEKRQAQQMERMMNDPAGKAFTLALADRVFRPSSPV
RGAELFRYLLDGYGVPRYLSAADRFAIKMGGRFSAQFPGVVMPVITSQLRKESSNVILPAEDGKLRPHLRRRRKGGIRMN
INQLGEAILGESEAHHRLQQVVDRLTDKDCDYISVKISAIFSQIHLVAFEETVKLIQERLRILYRAAITNAVTLPDGSRK
PKFVNLDMEEYRDLHLTAEAFKRTLMEDEFMQLEAGIVLQAYLPDSWEEQMKLCAWAKERVEQGGARIKIRLVKGANLAM
EKVEASMHGWAQAPYGTKAQVDANYKRMLHYGCMPDNARYVQFGVASHNLFDLCYAMLLREREGVRDQVEFEMLEGMANH
QARVIRQAADGLLLYAPVVLKEDFHSAIAYLVRRLDENTSEENFLHDLFGMTPGSRSWEVQKKRFLKACQEKDEVKYGPN
RTQNRAADPIQPSHYRDAFANERDTDWSLRQNAEWINGLIAAEKEKSGEEIPLVIDGEEITTNLWGVGRDPSRHNEVSYK
FAYADFDQVEHALVTADRVRSSWASKSIGERAEILHRAAQELSRIRGEAIAAMVRDAGKAPTEADVEVSEAIDFCRYYAE
GLDRDGMNDGVEMSPLGIICVMSPWNFPFAIPTGGVAAALMAGNAVVFKPSELAVYTAWQIVQAFWRAGVPKNVLQFVPM
PRNEISCKFLMDPRLNGVIMTGSYRTGKMLRELRPDLHVLAETSGKDAMIITATADPDQAVKDLVKSAFGHSGQKCSAAS
VAIVEASVYDNPAFLRQLKDAAASLKVGGSWEVNSVVTPLIREPEGNLLRALTQLEPGEEWLLKPEPSEDNPCLWSPGIR
LGVKPGSWFHQTECFGPVLGIIRAENLEEAIDIQNDSEFGLTGGLQSLDEREIALWKTKVQVGNAYINRVITGAIVRRQP
FGGWNHSSMGPGAKAGGPNYLTMLGSWEEKALPQKLRTPGERISGLVEKLCSELPDCAKRIRSAAGSQAKWWMEEFGVDH
DPSRVYGENNTFRYIPVKGILARVENMSDDDVAILLLGAKLCGVLLHLSIGTSRPWIQKMHGYYASLTVETEAELIGRMP
EALPGIRFLRGTDISETLANAARARDVEVLDRPVLANGRLELLGYFREQSVSETVHRYGNLIPPPGSFKTDSV

Sequences:

>Translated_1193_residues
MTDSSIPDMMAEARRGQWTDQQLAAKAVELAESILKQSNAGMRGKEKRQAQQMERMMNDPAGKAFTLALADRVFRPSSPV
RGAELFRYLLDGYGVPRYLSAADRFAIKMGGRFSAQFPGVVMPVITSQLRKESSNVILPAEDGKLRPHLRRRRKGGIRMN
INQLGEAILGESEAHHRLQQVVDRLTDKDCDYISVKISAIFSQIHLVAFEETVKLIQERLRILYRAAITNAVTLPDGSRK
PKFVNLDMEEYRDLHLTAEAFKRTLMEDEFMQLEAGIVLQAYLPDSWEEQMKLCAWAKERVEQGGARIKIRLVKGANLAM
EKVEASMHGWAQAPYGTKAQVDANYKRMLHYGCMPDNARYVQFGVASHNLFDLCYAMLLREREGVRDQVEFEMLEGMANH
QARVIRQAADGLLLYAPVVLKEDFHSAIAYLVRRLDENTSEENFLHDLFGMTPGSRSWEVQKKRFLKACQEKDEVKYGPN
RTQNRAADPIQPSHYRDAFANERDTDWSLRQNAEWINGLIAAEKEKSGEEIPLVIDGEEITTNLWGVGRDPSRHNEVSYK
FAYADFDQVEHALVTADRVRSSWASKSIGERAEILHRAAQELSRIRGEAIAAMVRDAGKAPTEADVEVSEAIDFCRYYAE
GLDRDGMNDGVEMSPLGIICVMSPWNFPFAIPTGGVAAALMAGNAVVFKPSELAVYTAWQIVQAFWRAGVPKNVLQFVPM
PRNEISCKFLMDPRLNGVIMTGSYRTGKMLRELRPDLHVLAETSGKDAMIITATADPDQAVKDLVKSAFGHSGQKCSAAS
VAIVEASVYDNPAFLRQLKDAAASLKVGGSWEVNSVVTPLIREPEGNLLRALTQLEPGEEWLLKPEPSEDNPCLWSPGIR
LGVKPGSWFHQTECFGPVLGIIRAENLEEAIDIQNDSEFGLTGGLQSLDEREIALWKTKVQVGNAYINRVITGAIVRRQP
FGGWNHSSMGPGAKAGGPNYLTMLGSWEEKALPQKLRTPGERISGLVEKLCSELPDCAKRIRSAAGSQAKWWMEEFGVDH
DPSRVYGENNTFRYIPVKGILARVENMSDDDVAILLLGAKLCGVLLHLSIGTSRPWIQKMHGYYASLTVETEAELIGRMP
EALPGIRFLRGTDISETLANAARARDVEVLDRPVLANGRLELLGYFREQSVSETVHRYGNLIPPPGSFKTDSV
>Mature_1192_residues
TDSSIPDMMAEARRGQWTDQQLAAKAVELAESILKQSNAGMRGKEKRQAQQMERMMNDPAGKAFTLALADRVFRPSSPVR
GAELFRYLLDGYGVPRYLSAADRFAIKMGGRFSAQFPGVVMPVITSQLRKESSNVILPAEDGKLRPHLRRRRKGGIRMNI
NQLGEAILGESEAHHRLQQVVDRLTDKDCDYISVKISAIFSQIHLVAFEETVKLIQERLRILYRAAITNAVTLPDGSRKP
KFVNLDMEEYRDLHLTAEAFKRTLMEDEFMQLEAGIVLQAYLPDSWEEQMKLCAWAKERVEQGGARIKIRLVKGANLAME
KVEASMHGWAQAPYGTKAQVDANYKRMLHYGCMPDNARYVQFGVASHNLFDLCYAMLLREREGVRDQVEFEMLEGMANHQ
ARVIRQAADGLLLYAPVVLKEDFHSAIAYLVRRLDENTSEENFLHDLFGMTPGSRSWEVQKKRFLKACQEKDEVKYGPNR
TQNRAADPIQPSHYRDAFANERDTDWSLRQNAEWINGLIAAEKEKSGEEIPLVIDGEEITTNLWGVGRDPSRHNEVSYKF
AYADFDQVEHALVTADRVRSSWASKSIGERAEILHRAAQELSRIRGEAIAAMVRDAGKAPTEADVEVSEAIDFCRYYAEG
LDRDGMNDGVEMSPLGIICVMSPWNFPFAIPTGGVAAALMAGNAVVFKPSELAVYTAWQIVQAFWRAGVPKNVLQFVPMP
RNEISCKFLMDPRLNGVIMTGSYRTGKMLRELRPDLHVLAETSGKDAMIITATADPDQAVKDLVKSAFGHSGQKCSAASV
AIVEASVYDNPAFLRQLKDAAASLKVGGSWEVNSVVTPLIREPEGNLLRALTQLEPGEEWLLKPEPSEDNPCLWSPGIRL
GVKPGSWFHQTECFGPVLGIIRAENLEEAIDIQNDSEFGLTGGLQSLDEREIALWKTKVQVGNAYINRVITGAIVRRQPF
GGWNHSSMGPGAKAGGPNYLTMLGSWEEKALPQKLRTPGERISGLVEKLCSELPDCAKRIRSAAGSQAKWWMEEFGVDHD
PSRVYGENNTFRYIPVKGILARVENMSDDDVAILLLGAKLCGVLLHLSIGTSRPWIQKMHGYYASLTVETEAELIGRMPE
ALPGIRFLRGTDISETLANAARARDVEVLDRPVLANGRLELLGYFREQSVSETVHRYGNLIPPPGSFKTDSV

Specific function: Oxidizes Proline To Glutamate For Use As A Carbon And Nitrogen Source And Also Function As A Transcriptional Repressor Of The Put Operon. [C]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family. RocA subfamily [H]

Homologues:

Organism=Homo sapiens, GI238859541, Length=484, Percent_Identity=29.5454545454545, Blast_Score=150, Evalue=8e-36,
Organism=Homo sapiens, GI25777736, Length=484, Percent_Identity=29.5454545454545, Blast_Score=150, Evalue=9e-36,
Organism=Homo sapiens, GI25777734, Length=484, Percent_Identity=29.5454545454545, Blast_Score=150, Evalue=9e-36,
Organism=Homo sapiens, GI153266822, Length=423, Percent_Identity=28.1323877068558, Blast_Score=141, Evalue=4e-33,
Organism=Homo sapiens, GI12007648, Length=463, Percent_Identity=26.7818574514039, Blast_Score=137, Evalue=9e-32,
Organism=Homo sapiens, GI25777730, Length=422, Percent_Identity=26.0663507109005, Blast_Score=130, Evalue=7e-30,
Organism=Homo sapiens, GI25777724, Length=428, Percent_Identity=28.5046728971963, Blast_Score=130, Evalue=1e-29,
Organism=Homo sapiens, GI21361176, Length=425, Percent_Identity=27.7647058823529, Blast_Score=127, Evalue=6e-29,
Organism=Homo sapiens, GI115387104, Length=434, Percent_Identity=26.4976958525346, Blast_Score=124, Evalue=6e-28,
Organism=Homo sapiens, GI21614513, Length=415, Percent_Identity=25.7831325301205, Blast_Score=123, Evalue=1e-27,
Organism=Homo sapiens, GI25777728, Length=402, Percent_Identity=28.6069651741293, Blast_Score=122, Evalue=2e-27,
Organism=Homo sapiens, GI4507229, Length=429, Percent_Identity=27.039627039627, Blast_Score=121, Evalue=3e-27,
Organism=Homo sapiens, GI25777732, Length=422, Percent_Identity=26.0663507109005, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI25777721, Length=442, Percent_Identity=26.6968325791855, Blast_Score=114, Evalue=6e-25,
Organism=Homo sapiens, GI11095441, Length=442, Percent_Identity=23.9819004524887, Blast_Score=110, Evalue=1e-23,
Organism=Homo sapiens, GI238814322, Length=411, Percent_Identity=23.8442822384428, Blast_Score=108, Evalue=4e-23,
Organism=Homo sapiens, GI25777726, Length=428, Percent_Identity=27.1028037383178, Blast_Score=106, Evalue=1e-22,
Organism=Homo sapiens, GI25952152, Length=270, Percent_Identity=28.5185185185185, Blast_Score=103, Evalue=1e-21,
Organism=Homo sapiens, GI188035924, Length=439, Percent_Identity=24.373576309795, Blast_Score=96, Evalue=3e-19,
Organism=Homo sapiens, GI310128103, Length=439, Percent_Identity=24.373576309795, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI310128093, Length=439, Percent_Identity=24.373576309795, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI73466520, Length=328, Percent_Identity=25.9146341463415, Blast_Score=94, Evalue=8e-19,
Organism=Homo sapiens, GI4557303, Length=328, Percent_Identity=25.9146341463415, Blast_Score=94, Evalue=8e-19,
Organism=Homo sapiens, GI310128091, Length=376, Percent_Identity=25, Blast_Score=89, Evalue=3e-17,
Organism=Homo sapiens, GI310128089, Length=253, Percent_Identity=25.6916996047431, Blast_Score=69, Evalue=4e-11,
Organism=Homo sapiens, GI310128097, Length=245, Percent_Identity=26.1224489795918, Blast_Score=68, Evalue=4e-11,
Organism=Escherichia coli, GI1787250, Length=894, Percent_Identity=29.3064876957494, Blast_Score=263, Evalue=6e-71,
Organism=Escherichia coli, GI1788042, Length=451, Percent_Identity=31.9290465631929, Blast_Score=163, Evalue=7e-41,
Organism=Escherichia coli, GI87081926, Length=448, Percent_Identity=28.7946428571429, Blast_Score=148, Evalue=2e-36,
Organism=Escherichia coli, GI1787684, Length=461, Percent_Identity=28.6334056399132, Blast_Score=147, Evalue=6e-36,
Organism=Escherichia coli, GI1789015, Length=436, Percent_Identity=28.2110091743119, Blast_Score=137, Evalue=4e-33,
Organism=Escherichia coli, GI87081896, Length=470, Percent_Identity=26.1702127659574, Blast_Score=130, Evalue=4e-31,
Organism=Escherichia coli, GI1787558, Length=407, Percent_Identity=27.2727272727273, Blast_Score=126, Evalue=7e-30,
Organism=Escherichia coli, GI1786504, Length=424, Percent_Identity=28.0660377358491, Blast_Score=123, Evalue=8e-29,
Organism=Escherichia coli, GI1787715, Length=470, Percent_Identity=24.6808510638298, Blast_Score=110, Evalue=6e-25,
Organism=Escherichia coli, GI87082295, Length=431, Percent_Identity=26.4501160092807, Blast_Score=106, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17534447, Length=484, Percent_Identity=28.099173553719, Blast_Score=152, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI25143874, Length=433, Percent_Identity=28.8683602771363, Blast_Score=145, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI25143876, Length=433, Percent_Identity=28.8683602771363, Blast_Score=145, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI71986308, Length=449, Percent_Identity=26.5033407572383, Blast_Score=124, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI32564151, Length=435, Percent_Identity=26.6666666666667, Blast_Score=122, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17562198, Length=424, Percent_Identity=25.4716981132075, Blast_Score=121, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI133930964, Length=428, Percent_Identity=25, Blast_Score=120, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI25144435, Length=423, Percent_Identity=25.7683215130024, Blast_Score=118, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI115534176, Length=394, Percent_Identity=27.9187817258883, Blast_Score=116, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI32564736, Length=398, Percent_Identity=25.8793969849246, Blast_Score=113, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71990744, Length=323, Percent_Identity=28.7925696594427, Blast_Score=110, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI115532534, Length=398, Percent_Identity=26.6331658291457, Blast_Score=109, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI71995606, Length=456, Percent_Identity=25.8771929824561, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17551164, Length=433, Percent_Identity=23.5565819861432, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17534119, Length=468, Percent_Identity=24.1452991452991, Blast_Score=100, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71995613, Length=413, Percent_Identity=26.1501210653753, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17564084, Length=322, Percent_Identity=27.0186335403727, Blast_Score=95, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25146391, Length=327, Percent_Identity=25.3822629969419, Blast_Score=90, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI32566756, Length=327, Percent_Identity=25.3822629969419, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25146394, Length=327, Percent_Identity=25.3822629969419, Blast_Score=89, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321826, Length=544, Percent_Identity=28.3088235294118, Blast_Score=158, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6324950, Length=436, Percent_Identity=25.9174311926606, Blast_Score=139, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6325196, Length=440, Percent_Identity=26.3636363636364, Blast_Score=137, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6323821, Length=425, Percent_Identity=24.4705882352941, Blast_Score=130, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6320917, Length=473, Percent_Identity=26.6384778012685, Blast_Score=128, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6323822, Length=411, Percent_Identity=24.0875912408759, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6319478, Length=446, Percent_Identity=24.8878923766816, Blast_Score=104, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6321828, Length=456, Percent_Identity=24.1228070175439, Blast_Score=101, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6323757, Length=325, Percent_Identity=27.0769230769231, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24668425, Length=485, Percent_Identity=30.1030927835052, Blast_Score=170, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24668417, Length=485, Percent_Identity=30.1030927835052, Blast_Score=170, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24668413, Length=485, Percent_Identity=30.1030927835052, Blast_Score=170, Evalue=5e-42,
Organism=Drosophila melanogaster, GI281362580, Length=421, Percent_Identity=29.9287410926366, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI62472918, Length=421, Percent_Identity=29.9287410926366, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI62472926, Length=421, Percent_Identity=29.9287410926366, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI62472936, Length=421, Percent_Identity=29.9287410926366, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI21356737, Length=421, Percent_Identity=29.9287410926366, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI28571798, Length=486, Percent_Identity=26.7489711934156, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571796, Length=486, Percent_Identity=26.7489711934156, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571794, Length=486, Percent_Identity=26.7489711934156, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571802, Length=486, Percent_Identity=26.7489711934156, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571800, Length=486, Percent_Identity=26.7489711934156, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571806, Length=486, Percent_Identity=26.7489711934156, Blast_Score=129, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24650465, Length=453, Percent_Identity=27.8145695364238, Blast_Score=127, Evalue=4e-29,
Organism=Drosophila melanogaster, GI20129399, Length=424, Percent_Identity=26.4150943396226, Blast_Score=124, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24638878, Length=410, Percent_Identity=25.8536585365854, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24638876, Length=410, Percent_Identity=25.8536585365854, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24585660, Length=440, Percent_Identity=22.5, Blast_Score=103, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24666674, Length=398, Percent_Identity=26.1306532663317, Blast_Score=101, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28574525, Length=453, Percent_Identity=23.6203090507726, Blast_Score=90, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281360299, Length=382, Percent_Identity=25.3926701570681, Blast_Score=83, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281360297, Length=382, Percent_Identity=25.3926701570681, Blast_Score=83, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281360295, Length=382, Percent_Identity=25.3926701570681, Blast_Score=83, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24586250, Length=382, Percent_Identity=25.3926701570681, Blast_Score=83, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281360301, Length=382, Percent_Identity=25.3926701570681, Blast_Score=83, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45552499, Length=382, Percent_Identity=25.130890052356, Blast_Score=82, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281360303, Length=382, Percent_Identity=25.130890052356, Blast_Score=81, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005932 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.5.1.12 [H]

Molecular weight: Translated: 133141; Mature: 133009

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSSIPDMMAEARRGQWTDQQLAAKAVELAESILKQSNAGMRGKEKRQAQQMERMMNDP
CCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
AGKAFTLALADRVFRPSSPVRGAELFRYLLDGYGVPRYLSAADRFAIKMGGRFSAQFPGV
CCCEEEHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHEEEECCEECCCCCCH
VMPVITSQLRKESSNVILPAEDGKLRPHLRRRRKGGIRMNINQLGEAILGESEAHHRLQQ
HHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHCCCCEEEHHHHHHHHHCCCHHHHHHHH
VVDRLTDKDCDYISVKISAIFSQIHLVAFEETVKLIQERLRILYRAAITNAVTLPDGSRK
HHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCC
PKFVNLDMEEYRDLHLTAEAFKRTLMEDEFMQLEAGIVLQAYLPDSWEEQMKLCAWAKER
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHH
VEQGGARIKIRLVKGANLAMEKVEASMHGWAQAPYGTKAQVDANYKRMLHYGCMPDNARY
HHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHCCCCCCCCE
VQFGVASHNLFDLCYAMLLREREGVRDQVEFEMLEGMANHQARVIRQAADGLLLYAPVVL
EEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHH
KEDFHSAIAYLVRRLDENTSEENFLHDLFGMTPGSRSWEVQKKRFLKACQEKDEVKYGPN
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
RTQNRAADPIQPSHYRDAFANERDTDWSLRQNAEWINGLIAAEKEKSGEEIPLVIDGEEI
CCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHCHHHHHHHHHHHHCCCCCCCCEEECCCHH
TTNLWGVGRDPSRHNEVSYKFAYADFDQVEHALVTADRVRSSWASKSIGERAEILHRAAQ
HHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELSRIRGEAIAAMVRDAGKAPTEADVEVSEAIDFCRYYAEGLDRDGMNDGVEMSPLGIIC
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCEEEE
VMSPWNFPFAIPTGGVAAALMAGNAVVFKPSELAVYTAWQIVQAFWRAGVPKNVLQFVPM
EECCCCCCEECCCCHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCC
PRNEISCKFLMDPRLNGVIMTGSYRTGKMLRELRPDLHVLAETSGKDAMIITATADPDQA
CCCCCCEEEEECCCCCCEEEECCCHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCHHHH
VKDLVKSAFGHSGQKCSAASVAIVEASVYDNPAFLRQLKDAAASLKVGGSWEVNSVVTPL
HHHHHHHHHCCCCCCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHEECCCCEEHHHHHHHH
IREPEGNLLRALTQLEPGEEWLLKPEPSEDNPCLWSPGIRLGVKPGSWFHQTECFGPVLG
HCCCCCHHHHHHHHCCCCHHCCCCCCCCCCCCEEECCCCEEECCCCCCCCHHHHHHHHHH
IIRAENLEEAIDIQNDSEFGLTGGLQSLDEREIALWKTKVQVGNAYINRVITGAIVRRQP
HHHHCCHHHHHCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FGGWNHSSMGPGAKAGGPNYLTMLGSWEEKALPQKLRTPGERISGLVEKLCSELPDCAKR
CCCCCCCCCCCCCCCCCCCEEEEECCCHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHH
IRSAAGSQAKWWMEEFGVDHDPSRVYGENNTFRYIPVKGILARVENMSDDDVAILLLGAK
HHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCEEEHHHHH
LCGVLLHLSIGTSRPWIQKMHGYYASLTVETEAELIGRMPEALPGIRFLRGTDISETLAN
HHHHHHHHHCCCCCHHHHHHCCEEEEEEEEHHHHHHHCCHHHCCCCEEECCCCHHHHHHH
AARARDVEVLDRPVLANGRLELLGYFREQSVSETVHRYGNLIPPPGSFKTDSV
HHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDSSIPDMMAEARRGQWTDQQLAAKAVELAESILKQSNAGMRGKEKRQAQQMERMMNDP
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
AGKAFTLALADRVFRPSSPVRGAELFRYLLDGYGVPRYLSAADRFAIKMGGRFSAQFPGV
CCCEEEHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHEEEECCEECCCCCCH
VMPVITSQLRKESSNVILPAEDGKLRPHLRRRRKGGIRMNINQLGEAILGESEAHHRLQQ
HHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHCCCCEEEHHHHHHHHHCCCHHHHHHHH
VVDRLTDKDCDYISVKISAIFSQIHLVAFEETVKLIQERLRILYRAAITNAVTLPDGSRK
HHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCC
PKFVNLDMEEYRDLHLTAEAFKRTLMEDEFMQLEAGIVLQAYLPDSWEEQMKLCAWAKER
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHH
VEQGGARIKIRLVKGANLAMEKVEASMHGWAQAPYGTKAQVDANYKRMLHYGCMPDNARY
HHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHCCCCCCCCE
VQFGVASHNLFDLCYAMLLREREGVRDQVEFEMLEGMANHQARVIRQAADGLLLYAPVVL
EEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHH
KEDFHSAIAYLVRRLDENTSEENFLHDLFGMTPGSRSWEVQKKRFLKACQEKDEVKYGPN
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
RTQNRAADPIQPSHYRDAFANERDTDWSLRQNAEWINGLIAAEKEKSGEEIPLVIDGEEI
CCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHCHHHHHHHHHHHHCCCCCCCCEEECCCHH
TTNLWGVGRDPSRHNEVSYKFAYADFDQVEHALVTADRVRSSWASKSIGERAEILHRAAQ
HHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELSRIRGEAIAAMVRDAGKAPTEADVEVSEAIDFCRYYAEGLDRDGMNDGVEMSPLGIIC
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCEEEE
VMSPWNFPFAIPTGGVAAALMAGNAVVFKPSELAVYTAWQIVQAFWRAGVPKNVLQFVPM
EECCCCCCEECCCCHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCC
PRNEISCKFLMDPRLNGVIMTGSYRTGKMLRELRPDLHVLAETSGKDAMIITATADPDQA
CCCCCCEEEEECCCCCCEEEECCCHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCHHHH
VKDLVKSAFGHSGQKCSAASVAIVEASVYDNPAFLRQLKDAAASLKVGGSWEVNSVVTPL
HHHHHHHHHCCCCCCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHEECCCCEEHHHHHHHH
IREPEGNLLRALTQLEPGEEWLLKPEPSEDNPCLWSPGIRLGVKPGSWFHQTECFGPVLG
HCCCCCHHHHHHHHCCCCHHCCCCCCCCCCCCEEECCCCEEECCCCCCCCHHHHHHHHHH
IIRAENLEEAIDIQNDSEFGLTGGLQSLDEREIALWKTKVQVGNAYINRVITGAIVRRQP
HHHHCCHHHHHCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FGGWNHSSMGPGAKAGGPNYLTMLGSWEEKALPQKLRTPGERISGLVEKLCSELPDCAKR
CCCCCCCCCCCCCCCCCCCEEEEECCCHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHH
IRSAAGSQAKWWMEEFGVDHDPSRVYGENNTFRYIPVKGILARVENMSDDDVAILLLGAK
HHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCEEEHHHHH
LCGVLLHLSIGTSRPWIQKMHGYYASLTVETEAELIGRMPEALPGIRFLRGTDISETLAN
HHHHHHHHHCCCCCHHHHHHCCEEEEEEEEHHHHHHHCCHHHCCCCEEECCCCHHHHHHH
AARARDVEVLDRPVLANGRLELLGYFREQSVSETVHRYGNLIPPPGSFKTDSV
HHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]