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The map label for this gene is sugE [H]

Identifier: 187735127

GI number: 187735127

Start: 729945

End: 730280

Strand: Reverse

Name: sugE [H]

Synonym: Amuc_0621

Alternate gene names: 187735127

Gene position: 730280-729945 (Counterclockwise)

Preceding gene: 187735131

Following gene: 187735125

Centisome position: 27.41

GC content: 57.14

Gene sequence:

>336_bases
ATGTCCTGGATTTATCTGGTGTTGGCCGGTCTCTGCGAGATCGGATGGCCTCTGGGTTTCAAACTTTCTCAAACGCCCGG
CACTGGGCCCGGCAAATTCGCCGCCTGTATCGCCTGCTCCGTTTTCAGCATGGTTCTGAGCGGTTTTCTTTTGTGGCTTG
CCCAGCGGAACATCCCCATCGGCACCGCTTATGCGGTATGGACCGGCATTGGCGCGTTGGGCACGTTCCTGGTTGGTATT
CTGTGGTTCGGGGATTCTTCCAATATCTGGCGCATGCTGGCGGCATCCTTCCTGCTGATAGGCATTATCGGGCTGAAGTT
GGCCCCCGGGCATTGA

Upstream 100 bases:

>100_bases
CGGAAACGCCGGGCAGATATTCTGCAGGGCATCCGTTGCCCTTGGAGCTTTTTCCGTTTGGGAAGGCCGGTGAGCGGAAG
GTGATTCCCCGTTTCGATAT

Downstream 100 bases:

>100_bases
TGCGGTCTTCGGCATCCTTGCCGGGTTCCGGGAAAAGCCGTCTCCGCAACTTTCCGGATAGGAGGTCTCAGTAGTGGGGG
ATGGCTTTTTCCCACACGGT

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 111; Mature: 110

Protein sequence:

>111_residues
MSWIYLVLAGLCEIGWPLGFKLSQTPGTGPGKFAACIACSVFSMVLSGFLLWLAQRNIPIGTAYAVWTGIGALGTFLVGI
LWFGDSSNIWRMLAASFLLIGIIGLKLAPGH

Sequences:

>Translated_111_residues
MSWIYLVLAGLCEIGWPLGFKLSQTPGTGPGKFAACIACSVFSMVLSGFLLWLAQRNIPIGTAYAVWTGIGALGTFLVGI
LWFGDSSNIWRMLAASFLLIGIIGLKLAPGH
>Mature_110_residues
SWIYLVLAGLCEIGWPLGFKLSQTPGTGPGKFAACIACSVFSMVLSGFLLWLAQRNIPIGTAYAVWTGIGALGTFLVGIL
WFGDSSNIWRMLAASFLLIGIIGLKLAPGH

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=108, Percent_Identity=43.5185185185185, Blast_Score=85, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11804; Mature: 11673

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWIYLVLAGLCEIGWPLGFKLSQTPGTGPGKFAACIACSVFSMVLSGFLLWLAQRNIPI
CHHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GTAYAVWTGIGALGTFLVGILWFGDSSNIWRMLAASFLLIGIIGLKLAPGH
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SWIYLVLAGLCEIGWPLGFKLSQTPGTGPGKFAACIACSVFSMVLSGFLLWLAQRNIPI
HHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GTAYAVWTGIGALGTFLVGILWFGDSSNIWRMLAASFLLIGIIGLKLAPGH
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3308458 [H]