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The map label for this gene is atsA [H]

Identifier: 187735071

GI number: 187735071

Start: 664189

End: 665817

Strand: Direct

Name: atsA [H]

Synonym: Amuc_0565

Alternate gene names: 187735071

Gene position: 664189-665817 (Clockwise)

Preceding gene: 187735070

Following gene: 187735073

Centisome position: 24.93

GC content: 57.03

Gene sequence:

>1629_bases
ATGATATTCCATATTCCTTTCATGTGCTCTACCCTGCGTTCCTCCATCATGTCCAGCATAGCCTTCTGGTTGCTTACCCT
TGTCCCTTCACTGGCGGACAGGCCTAATATCGTCCTTATCCTGGCTGATGACATGGGATGGTCCGACCCGGGCTGCTACG
GTTCGGAAATACCCACTCCAGCCCTGGATACCCTGGCCAGACAGGGGATGCTGGCAACCCGGCTCTACACCGCTTCCCGC
TGTTCACCCTCCCGGGCCTCCATCATGACCGGCTGCGAACCTCACAAGGTGGACGTAGGGCTCCTGGATGACGACAGCGG
GCGCCCCGGCTACCGCGGACGCCTGAACCCGGGTATCCCCACCCTGCCGGAACTTCTGAAAAAAGCGGGATACCGTACCT
ATCTTTCCGGGAAATGGCATCTTGGAAAAGTTCGGGGATCCTACCCATGGGACCGCGGCTTCGACCGTTCCCGCGGTTTG
CTGGGTGGAGCGGCAGATTACTACAGGCCCATGCCGGACAGCCCCTTCGGTGAAAACGGGAAACTGCTCCGTCCGGAGGA
TCTGCCGGAGGATTTCTACATGACGGACGATATCACCAAAACGGCTCTGGCCTATATTGGCGATGCCGCCAAAAGCAGGC
AGCCCTTCTTCCTTTACGTGGCTTATACGGCTCCGCATACACCCCTCCAGGCCCCCCGGAGGGAAATAGAAAAAATGCTC
CCGTTCTACAACGGCAAATCCCCCCATGCCATTGCTTCCAAAAGACTGGAAAAACAAAAGCTGCTGGGAATCGTCCCTCC
TGCCGCCAAACTGGGCATGGCCGGCAAATTCAATCCAGAAGGCTATGAAAAAACTTCCGCAAAGCGGAAGGATTATATTG
CCGAATGCATGGCCACCTACGCCGCCCAAATCGTTATCATGGACCGCGGCATAGGCCGCATTCTCGCGTCCCTAGAACGT
CACCGCCTCAGTGACAATACCATCGTCATGTTTTTATCAGACAATGGCGCAACAGCGGAAATGCCCCAGAACAATAAAAA
CAAGAAGACTACCCTCCCCACAGGCCCGCTGGGAGAAGTCGGATGCAGGGACGGATACGGCCCCATGTGGGCGGCTGTGT
CCAATACCCCTTACCGCCAGTATAAAATAGAAACCTTTGACGGAGGGCTGTCCGCCCCCTTCATCATTCGCTACCCTTCC
AAAATACGTCCGGGATCGCGCTACCACTCGCCTTTCCTGCTTCAGGACATCGCCCCAACCTGCCTTGCGTGGGCCGCTCT
CCCAATTCCGGCCCATATGGACGGCAAGCCGCTCAACACCTACTGGAATAATCCTCCGGAACTTCCTCCGTCCAAGGTGT
GGGACTTCATTCCCAATACCTGCCCTCCCCGCACTATCTTCTGGGAACATCAGAGGAACCGGGCGGCCCTGACAAGTCAA
TTCAAGCTGGTGGCCCCCAACCGCGGCCCCTGGCAGGTGTACGACATCAGGGACAGGACGGAACAGAACAATCTGGCATC
CAGGCACCAGACGCTTGTAGAACAATTGTCCGCACAGTACAGGAAATGGGCGGCGGAAAACCATGCCGAACGACACAGCC
CGGCAGAAAAACGGGCATACGCGCCCTAA

Upstream 100 bases:

>100_bases
AGGCCTCCGGCAAAAACAGGCATACGCAGGACGGATCTTTCCGGAACGGCCTGTTTTTTCCTCCTGCTGCAAGAATCAAT
AGCGGTTCCGCTTATTATAT

Downstream 100 bases:

>100_bases
ACGTTTCTATGGGAATCCCCTTCCGGAAGAAAATTCTGATTTCCGTTTCCTCAAGTAACGGAAAACGGCATGTGATTCAC
CGGGAAAGAAAAAGCAGGGA

Product: sulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MIFHIPFMCSTLRSSIMSSIAFWLLTLVPSLADRPNIVLILADDMGWSDPGCYGSEIPTPALDTLARQGMLATRLYTASR
CSPSRASIMTGCEPHKVDVGLLDDDSGRPGYRGRLNPGIPTLPELLKKAGYRTYLSGKWHLGKVRGSYPWDRGFDRSRGL
LGGAADYYRPMPDSPFGENGKLLRPEDLPEDFYMTDDITKTALAYIGDAAKSRQPFFLYVAYTAPHTPLQAPRREIEKML
PFYNGKSPHAIASKRLEKQKLLGIVPPAAKLGMAGKFNPEGYEKTSAKRKDYIAECMATYAAQIVIMDRGIGRILASLER
HRLSDNTIVMFLSDNGATAEMPQNNKNKKTTLPTGPLGEVGCRDGYGPMWAAVSNTPYRQYKIETFDGGLSAPFIIRYPS
KIRPGSRYHSPFLLQDIAPTCLAWAALPIPAHMDGKPLNTYWNNPPELPPSKVWDFIPNTCPPRTIFWEHQRNRAALTSQ
FKLVAPNRGPWQVYDIRDRTEQNNLASRHQTLVEQLSAQYRKWAAENHAERHSPAEKRAYAP

Sequences:

>Translated_542_residues
MIFHIPFMCSTLRSSIMSSIAFWLLTLVPSLADRPNIVLILADDMGWSDPGCYGSEIPTPALDTLARQGMLATRLYTASR
CSPSRASIMTGCEPHKVDVGLLDDDSGRPGYRGRLNPGIPTLPELLKKAGYRTYLSGKWHLGKVRGSYPWDRGFDRSRGL
LGGAADYYRPMPDSPFGENGKLLRPEDLPEDFYMTDDITKTALAYIGDAAKSRQPFFLYVAYTAPHTPLQAPRREIEKML
PFYNGKSPHAIASKRLEKQKLLGIVPPAAKLGMAGKFNPEGYEKTSAKRKDYIAECMATYAAQIVIMDRGIGRILASLER
HRLSDNTIVMFLSDNGATAEMPQNNKNKKTTLPTGPLGEVGCRDGYGPMWAAVSNTPYRQYKIETFDGGLSAPFIIRYPS
KIRPGSRYHSPFLLQDIAPTCLAWAALPIPAHMDGKPLNTYWNNPPELPPSKVWDFIPNTCPPRTIFWEHQRNRAALTSQ
FKLVAPNRGPWQVYDIRDRTEQNNLASRHQTLVEQLSAQYRKWAAENHAERHSPAEKRAYAP
>Mature_542_residues
MIFHIPFMCSTLRSSIMSSIAFWLLTLVPSLADRPNIVLILADDMGWSDPGCYGSEIPTPALDTLARQGMLATRLYTASR
CSPSRASIMTGCEPHKVDVGLLDDDSGRPGYRGRLNPGIPTLPELLKKAGYRTYLSGKWHLGKVRGSYPWDRGFDRSRGL
LGGAADYYRPMPDSPFGENGKLLRPEDLPEDFYMTDDITKTALAYIGDAAKSRQPFFLYVAYTAPHTPLQAPRREIEKML
PFYNGKSPHAIASKRLEKQKLLGIVPPAAKLGMAGKFNPEGYEKTSAKRKDYIAECMATYAAQIVIMDRGIGRILASLER
HRLSDNTIVMFLSDNGATAEMPQNNKNKKTTLPTGPLGEVGCRDGYGPMWAAVSNTPYRQYKIETFDGGLSAPFIIRYPS
KIRPGSRYHSPFLLQDIAPTCLAWAALPIPAHMDGKPLNTYWNNPPELPPSKVWDFIPNTCPPRTIFWEHQRNRAALTSQ
FKLVAPNRGPWQVYDIRDRTEQNNLASRHQTLVEQLSAQYRKWAAENHAERHSPAEKRAYAP

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI38569407, Length=441, Percent_Identity=27.891156462585, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI109389362, Length=398, Percent_Identity=28.391959798995, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI38569405, Length=441, Percent_Identity=28.3446712018141, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI59797060, Length=307, Percent_Identity=31.9218241042345, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI53831991, Length=458, Percent_Identity=27.5109170305677, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI4503899, Length=254, Percent_Identity=33.0708661417323, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI157266309, Length=467, Percent_Identity=25.9100642398287, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI4506919, Length=574, Percent_Identity=24.0418118466899, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI58743319, Length=427, Percent_Identity=25.9953161592506, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI31742482, Length=152, Percent_Identity=39.4736842105263, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI45430057, Length=228, Percent_Identity=34.2105263157895, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI146229331, Length=132, Percent_Identity=43.1818181818182, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI146229329, Length=132, Percent_Identity=43.1818181818182, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI6005990, Length=132, Percent_Identity=43.1818181818182, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI146229324, Length=132, Percent_Identity=43.1818181818182, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI71852586, Length=145, Percent_Identity=40, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI71852584, Length=145, Percent_Identity=40, Blast_Score=80, Evalue=6e-15,
Organism=Escherichia coli, GI87081924, Length=579, Percent_Identity=24.1796200345423, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790233, Length=438, Percent_Identity=26.7123287671233, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790112, Length=323, Percent_Identity=25.6965944272446, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI115533416, Length=424, Percent_Identity=26.6509433962264, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI115533418, Length=417, Percent_Identity=26.378896882494, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17559078, Length=263, Percent_Identity=28.1368821292776, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281366397, Length=434, Percent_Identity=30.4147465437788, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI281366395, Length=434, Percent_Identity=30.4147465437788, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24666163, Length=434, Percent_Identity=30.4147465437788, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24666109, Length=422, Percent_Identity=30.0947867298578, Blast_Score=138, Evalue=8e-33,
Organism=Drosophila melanogaster, GI281363223, Length=346, Percent_Identity=29.4797687861272, Blast_Score=129, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24666175, Length=443, Percent_Identity=28.4424379232506, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24653364, Length=438, Percent_Identity=26.2557077625571, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI19922168, Length=413, Percent_Identity=25.6658595641646, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24656835, Length=457, Percent_Identity=26.6958424507659, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 60718; Mature: 60718

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFHIPFMCSTLRSSIMSSIAFWLLTLVPSLADRPNIVLILADDMGWSDPGCYGSEIPTP
CEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCH
ALDTLARQGMLATRLYTASRCSPSRASIMTGCEPHKVDVGLLDDDSGRPGYRGRLNPGIP
HHHHHHHCCHHHHHHHHHHCCCCCHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCC
TLPELLKKAGYRTYLSGKWHLGKVRGSYPWDRGFDRSRGLLGGAADYYRPMPDSPFGENG
HHHHHHHHCCCEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCC
KLLRPEDLPEDFYMTDDITKTALAYIGDAAKSRQPFFLYVAYTAPHTPLQAPRREIEKML
CEECCCCCCCCCEECCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHC
PFYNGKSPHAIASKRLEKQKLLGIVPPAAKLGMAGKFNPEGYEKTSAKRKDYIAECMATY
CCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AAQIVIMDRGIGRILASLERHRLSDNTIVMFLSDNGATAEMPQNNKNKKTTLPTGPLGEV
HHEEEEEECCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
GCRDGYGPMWAAVSNTPYRQYKIETFDGGLSAPFIIRYPSKIRPGSRYHSPFLLQDIAPT
CCCCCCCCEEEEECCCCCEEEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHH
CLAWAALPIPAHMDGKPLNTYWNNPPELPPSKVWDFIPNTCPPRTIFWEHQRNRAALTSQ
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEECCCCCCHHHHCC
FKLVAPNRGPWQVYDIRDRTEQNNLASRHQTLVEQLSAQYRKWAAENHAERHSPAEKRAY
EEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
AP
CC
>Mature Secondary Structure
MIFHIPFMCSTLRSSIMSSIAFWLLTLVPSLADRPNIVLILADDMGWSDPGCYGSEIPTP
CEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCH
ALDTLARQGMLATRLYTASRCSPSRASIMTGCEPHKVDVGLLDDDSGRPGYRGRLNPGIP
HHHHHHHCCHHHHHHHHHHCCCCCHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCC
TLPELLKKAGYRTYLSGKWHLGKVRGSYPWDRGFDRSRGLLGGAADYYRPMPDSPFGENG
HHHHHHHHCCCEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCC
KLLRPEDLPEDFYMTDDITKTALAYIGDAAKSRQPFFLYVAYTAPHTPLQAPRREIEKML
CEECCCCCCCCCEECCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHC
PFYNGKSPHAIASKRLEKQKLLGIVPPAAKLGMAGKFNPEGYEKTSAKRKDYIAECMATY
CCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AAQIVIMDRGIGRILASLERHRLSDNTIVMFLSDNGATAEMPQNNKNKKTTLPTGPLGEV
HHEEEEEECCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
GCRDGYGPMWAAVSNTPYRQYKIETFDGGLSAPFIIRYPSKIRPGSRYHSPFLLQDIAPT
CCCCCCCCEEEEECCCCCEEEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHH
CLAWAALPIPAHMDGKPLNTYWNNPPELPPSKVWDFIPNTCPPRTIFWEHQRNRAALTSQ
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEECCCCCCHHHHCC
FKLVAPNRGPWQVYDIRDRTEQNNLASRHQTLVEQLSAQYRKWAAENHAERHSPAEKRAY
EEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
AP
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7744061; 10984043 [H]