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The map label for this gene is moeZ [H]

Identifier: 187735029

GI number: 187735029

Start: 614418

End: 615197

Strand: Direct

Name: moeZ [H]

Synonym: Amuc_0522

Alternate gene names: 187735029

Gene position: 614418-615197 (Clockwise)

Preceding gene: 187735028

Following gene: 187735030

Centisome position: 23.06

GC content: 63.46

Gene sequence:

>780_bases
ATGACCCTCACCCAGGAAGAAACCGAACGGTACGCCAGGCATCTTTCCCTTCCGGAACTGGGAGAACAGGGCCAATACAA
ACTCAAACGGGCGCATGTCGCCCTGACGGGCCTCGGGGGGCTTGGCTCCCCGGCGGCCCTTTATCTTGCTGCCGCAGGCG
TGGGGCGCCTGACCCTGATTGACCCGGACGAGGTGTGTCTTTCCAACCTCCAGCGGCAAATCCTGCATGCCACGGATGCG
GCGGGAACGGCTAAAACCGCCAGCGCCGCCAGACGCCTGTACGCCCTGAACCCCTCCGTACGCATCAACACGGTCCACAG
GCGCCTTACGCCGGAAAATGCCGTTTCCCTGCTGGAAGGGTGCGACCTGGTTCTGGACGCTTCAGACAATTACGCGGCAC
GCTTCGCCATGGCGGATGCCGCCTGCACCCTGCGCATTCCGCTGGTGTACGGCGCCGTGAAGGGCTTTATCGGGCAGGTG
GCCGTTTTCGCCCCCCATCAGGGAACCGCCTGTTACCGCTGCCTCTTCCCGGCAGATACGCCCATGCAGGAAAAAGACAC
CGCCTCCGCCGCAGGCATTCTGGGTGCGCATGCGGGCATCATCGGCTGCATCCAGGCCATGGAAGCCCTGAAATATCTTG
CGGGCATTCCCTCTCCGCTGGTGGGCGCCATGCTCTCTGCGGACACGCGGCGCATGCGCTTCACCACCATCCCTCTGGCG
CCTAATCCCGCGTGCAGATGCCGGACTAACGAGGGGTGCGGAGCCGCAATGAAAAATTGA

Upstream 100 bases:

>100_bases
TAGGTACTCTGATCGCAGTGGAACTGATCTTCTCCGGGTGGACGCTGCTCCTGTATGCATTCAGCGGCAATTCCGCCCGC
CGTTAATCCCAGTGACAACA

Downstream 100 bases:

>100_bases
CGGCGACGGCGGCATCTGGCATCATTTCCGGCAGGTATGAATCATTTAACACGCGCCAAATCCGTTTTTGAAATGGAGAT
TGAAGAGCTGCGCGGCGTCC

Product: UBA/THIF-type NAD/FAD binding protein

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MTLTQEETERYARHLSLPELGEQGQYKLKRAHVALTGLGGLGSPAALYLAAAGVGRLTLIDPDEVCLSNLQRQILHATDA
AGTAKTASAARRLYALNPSVRINTVHRRLTPENAVSLLEGCDLVLDASDNYAARFAMADAACTLRIPLVYGAVKGFIGQV
AVFAPHQGTACYRCLFPADTPMQEKDTASAAGILGAHAGIIGCIQAMEALKYLAGIPSPLVGAMLSADTRRMRFTTIPLA
PNPACRCRTNEGCGAAMKN

Sequences:

>Translated_259_residues
MTLTQEETERYARHLSLPELGEQGQYKLKRAHVALTGLGGLGSPAALYLAAAGVGRLTLIDPDEVCLSNLQRQILHATDA
AGTAKTASAARRLYALNPSVRINTVHRRLTPENAVSLLEGCDLVLDASDNYAARFAMADAACTLRIPLVYGAVKGFIGQV
AVFAPHQGTACYRCLFPADTPMQEKDTASAAGILGAHAGIIGCIQAMEALKYLAGIPSPLVGAMLSADTRRMRFTTIPLA
PNPACRCRTNEGCGAAMKN
>Mature_258_residues
TLTQEETERYARHLSLPELGEQGQYKLKRAHVALTGLGGLGSPAALYLAAAGVGRLTLIDPDEVCLSNLQRQILHATDAA
GTAKTASAARRLYALNPSVRINTVHRRLTPENAVSLLEGCDLVLDASDNYAARFAMADAACTLRIPLVYGAVKGFIGQVA
VFAPHQGTACYRCLFPADTPMQEKDTASAAGILGAHAGIIGCIQAMEALKYLAGIPSPLVGAMLSADTRRMRFTTIPLAP
NPACRCRTNEGCGAAMKN

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=232, Percent_Identity=43.9655172413793, Blast_Score=158, Evalue=5e-39,
Organism=Homo sapiens, GI13376212, Length=260, Percent_Identity=28.8461538461538, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787048, Length=252, Percent_Identity=40.0793650793651, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI87082356, Length=236, Percent_Identity=39.8305084745763, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1789177, Length=130, Percent_Identity=37.6923076923077, Blast_Score=86, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17540406, Length=253, Percent_Identity=33.9920948616601, Blast_Score=159, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI193203301, Length=169, Percent_Identity=27.810650887574, Blast_Score=74, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6321903, Length=215, Percent_Identity=36.7441860465116, Blast_Score=144, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24582879, Length=244, Percent_Identity=43.8524590163934, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24660640, Length=182, Percent_Identity=30.2197802197802, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641311, Length=264, Percent_Identity=31.4393939393939, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 27379; Mature: 27248

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTQEETERYARHLSLPELGEQGQYKLKRAHVALTGLGGLGSPAALYLAAAGVGRLTLI
CCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHEEEEEECCCCCCHHHHHHHHCCCCEEEEE
DPDEVCLSNLQRQILHATDAAGTAKTASAARRLYALNPSVRINTVHRRLTPENAVSLLEG
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEECCCCEEEEHHHHHCCHHHHHHHHHC
CDLVLDASDNYAARFAMADAACTLRIPLVYGAVKGFIGQVAVFAPHQGTACYRCLFPADT
CCEEEECCCCCEEEEEECCCEEEEEHHHHHHHHHHHHHCEEEECCCCCCEEEEEECCCCC
PMQEKDTASAAGILGAHAGIIGCIQAMEALKYLAGIPSPLVGAMLSADTRRMRFTTIPLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEEECCC
PNPACRCRTNEGCGAAMKN
CCCCCEEECCCCCCCCCCC
>Mature Secondary Structure 
TLTQEETERYARHLSLPELGEQGQYKLKRAHVALTGLGGLGSPAALYLAAAGVGRLTLI
CCCHHHHHHHHHHCCCCCCCCCCCHHHHHHEEEEEECCCCCCHHHHHHHHCCCCEEEEE
DPDEVCLSNLQRQILHATDAAGTAKTASAARRLYALNPSVRINTVHRRLTPENAVSLLEG
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEECCCCEEEEHHHHHCCHHHHHHHHHC
CDLVLDASDNYAARFAMADAACTLRIPLVYGAVKGFIGQVAVFAPHQGTACYRCLFPADT
CCEEEECCCCCEEEEEECCCEEEEEHHHHHHHHHHHHHCEEEECCCCCCEEEEEECCCCC
PMQEKDTASAAGILGAHAGIIGCIQAMEALKYLAGIPSPLVGAMLSADTRRMRFTTIPLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEEECCC
PNPACRCRTNEGCGAAMKN
CCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]