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The map label for this gene is aroK [H]

Identifier: 187734782

GI number: 187734782

Start: 332656

End: 333210

Strand: Direct

Name: aroK [H]

Synonym: Amuc_0270

Alternate gene names: 187734782

Gene position: 332656-333210 (Clockwise)

Preceding gene: 187734774

Following gene: 187734790

Centisome position: 12.49

GC content: 50.99

Gene sequence:

>555_bases
ATGAATAGGGCCGCATCAACATCCTTGCCAAACATCATCCTGATCGGGCTGATGGGATGCGGCAAAACTACCATCGGAAA
GGAACTGCACCGGGAAACGAACCTTGGTTTTACGGATACGGACCAGTTAATCGAACGCCAGACGGGAATGCACATTCCGC
AGATTTTCAAAATTCATGGGGAATCACATTTTCGAGACCTGGAAACCGGAATCCTGCAACAGCTTCAGACGGCCGCCGCA
CAAAGCCGCATTATTTCCACAGGAGGAGGCATCATTATCAGACCGGAAAACCGGCTGCTACTGAAAAAACTGGGCTTCGT
CGTCTGGCTCCATACAGACGTAAACATCCTGTACCAGCGTATTTCCAGATGCACCAACCGCCCCCTGCTCCAACAACCCA
ATCCCAAGGCCGTGCTGGAACATCTCATGAATGAACGGCATGATTTTTACCAGGAAACGGCGCACTTGACCATTGATACG
GCCAATCTCCACATCCATGAAATCGCATTCGGCATTCTGGAATCCGCCAGAGTATTCCGGTCCCGACGGCAATAA

Upstream 100 bases:

>100_bases
TCCACCCTTACGGACTTCCCCGAGTGAAAGCTGGCGCAGGAAAAGGCCATTCCGCTAAAAAGTTGTTTTCTCACGCTACC
GGATTGAGTACAATCAAGCC

Downstream 100 bases:

>100_bases
TGCCGACCCGTTTTTCCGTGAGCGGGAAATTTTCTCTTTCTGATTCATCCTAACGCAAGCGCTTCCGGGGAAGCCCTTTT
TCCCGCTCCACGCACAAGAA

Product: Shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MNRAASTSLPNIILIGLMGCGKTTIGKELHRETNLGFTDTDQLIERQTGMHIPQIFKIHGESHFRDLETGILQQLQTAAA
QSRIISTGGGIIIRPENRLLLKKLGFVVWLHTDVNILYQRISRCTNRPLLQQPNPKAVLEHLMNERHDFYQETAHLTIDT
ANLHIHEIAFGILESARVFRSRRQ

Sequences:

>Translated_184_residues
MNRAASTSLPNIILIGLMGCGKTTIGKELHRETNLGFTDTDQLIERQTGMHIPQIFKIHGESHFRDLETGILQQLQTAAA
QSRIISTGGGIIIRPENRLLLKKLGFVVWLHTDVNILYQRISRCTNRPLLQQPNPKAVLEHLMNERHDFYQETAHLTIDT
ANLHIHEIAFGILESARVFRSRRQ
>Mature_184_residues
MNRAASTSLPNIILIGLMGCGKTTIGKELHRETNLGFTDTDQLIERQTGMHIPQIFKIHGESHFRDLETGILQQLQTAAA
QSRIISTGGGIIIRPENRLLLKKLGFVVWLHTDVNILYQRISRCTNRPLLQQPNPKAVLEHLMNERHDFYQETAHLTIDT
ANLHIHEIAFGILESARVFRSRRQ

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=164, Percent_Identity=39.0243902439024, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1786587, Length=154, Percent_Identity=35.7142857142857, Blast_Score=94, Evalue=6e-21,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 20948; Mature: 20948

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRAASTSLPNIILIGLMGCGKTTIGKELHRETNLGFTDTDQLIERQTGMHIPQIFKIHG
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHEEECC
ESHFRDLETGILQQLQTAAAQSRIISTGGGIIIRPENRLLLKKLGFVVWLHTDVNILYQR
CHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEECCCCHHHHHHHCEEEEEECCHHHHHHH
ISRCTNRPLLQQPNPKAVLEHLMNERHDFYQETAHLTIDTANLHIHEIAFGILESARVFR
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHH
SRRQ
HCCC
>Mature Secondary Structure
MNRAASTSLPNIILIGLMGCGKTTIGKELHRETNLGFTDTDQLIERQTGMHIPQIFKIHG
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHEEECC
ESHFRDLETGILQQLQTAAAQSRIISTGGGIIIRPENRLLLKKLGFVVWLHTDVNILYQR
CHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEECCCCHHHHHHHCEEEEEECCHHHHHHH
ISRCTNRPLLQQPNPKAVLEHLMNERHDFYQETAHLTIDTANLHIHEIAFGILESARVFR
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHH
SRRQ
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA