| Definition | Akkermansia muciniphila ATCC BAA-835, complete genome. |
|---|---|
| Accession | NC_010655 |
| Length | 2,664,102 |
Click here to switch to the map view.
The map label for this gene is kch [C]
Identifier: 187734748
GI number: 187734748
Start: 294621
End: 295391
Strand: Reverse
Name: kch [C]
Synonym: Amuc_0236
Alternate gene names: 187734748
Gene position: 295391-294621 (Counterclockwise)
Preceding gene: 187734749
Following gene: 187734745
Centisome position: 11.09
GC content: 50.97
Gene sequence:
>771_bases ATGCCCCAAATTACCCGCACCAAGCTGGGCGCTGCCAATTTCGGTCCCTGGGAGAACATTGTCAGGGTACTGATTCTGGT ATGGTTCATGCTGTACACGTTGAATGCCATTCCGGATATTCATCCTCTGGTAGGCCGTATCGCGGCCAAGGTGAATTACT GGATCAGCTATTTCTTCATGTTTGAGTATATCCTGCGGGTGCTGTGCGCCAAACCGCGGAAGGCTTATATTTTCAGCGGC ATGGGTATTCTGGATTTTATTGTCTGCGTGCCGTTCCTGGGCATGTTTTTCGGGACGGACTGGCAGATTCTTTATTCCCT GAGGATTGTCCGCATACTGGCTATTTTCAAGTTGGCCCGGTTTAATGAAACCGCCGCCAGTTTTAAAAAGGCTTTCTACC TGATCCGGGATGAGTTTTTTCTGTTTTTCTCCGTGATCCTGTTCATGCTGTACGTCACTTCCCTGGGAATTTATATTGCA GAGCACGATGCCCAGCCCGAGAAATTCGGTTCCTTTTTTGACGCGCTCTGGTTTGCCGTGGAAACGTTGAGTACGGTCGG GTACGGAGACCTGGTGCCTATTACGCCCATGGGGCGTATTTTTACCGGGGTGATTATGTTTATTGCCGTGTCCATCATTG CTATTTCCACAGGGCTGATCACGTCTGCTTTTTCCCGCGTATGGCAGCAGGAGAATGTTTTTGCGCACCGTCATAAGCGG GACGCAGACAAGGTGGCGGCGGAGGCCGGGGAGGAGGAAGTACCCAAGTAG
Upstream 100 bases:
>100_bases GCATGCTGGTTAAACGCCCCATTTTTATTACCAATGGAAAGATATGCGTCGGCTTCAAGGCTGACGAGTGGAAGGCCGCC CATCGTTCCTAATTCCCGCC
Downstream 100 bases:
>100_bases GTTTGGCCCGCTTCCCGTGGATTTTTGACACCGGTTTCAAAAAGAACGGCCGCCTTTCCCAAAGAAAGGCGGCCGTTGCG TAAGAGGGACAAGGCTGTAT
Product: Ion transport 2 domain protein
Products: K (I) [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 256; Mature: 255
Protein sequence:
>256_residues MPQITRTKLGAANFGPWENIVRVLILVWFMLYTLNAIPDIHPLVGRIAAKVNYWISYFFMFEYILRVLCAKPRKAYIFSG MGILDFIVCVPFLGMFFGTDWQILYSLRIVRILAIFKLARFNETAASFKKAFYLIRDEFFLFFSVILFMLYVTSLGIYIA EHDAQPEKFGSFFDALWFAVETLSTVGYGDLVPITPMGRIFTGVIMFIAVSIIAISTGLITSAFSRVWQQENVFAHRHKR DADKVAAEAGEEEVPK
Sequences:
>Translated_256_residues MPQITRTKLGAANFGPWENIVRVLILVWFMLYTLNAIPDIHPLVGRIAAKVNYWISYFFMFEYILRVLCAKPRKAYIFSG MGILDFIVCVPFLGMFFGTDWQILYSLRIVRILAIFKLARFNETAASFKKAFYLIRDEFFLFFSVILFMLYVTSLGIYIA EHDAQPEKFGSFFDALWFAVETLSTVGYGDLVPITPMGRIFTGVIMFIAVSIIAISTGLITSAFSRVWQQENVFAHRHKR DADKVAAEAGEEEVPK >Mature_255_residues PQITRTKLGAANFGPWENIVRVLILVWFMLYTLNAIPDIHPLVGRIAAKVNYWISYFFMFEYILRVLCAKPRKAYIFSGM GILDFIVCVPFLGMFFGTDWQILYSLRIVRILAIFKLARFNETAASFKKAFYLIRDEFFLFFSVILFMLYVTSLGIYIAE HDAQPEKFGSFFDALWFAVETLSTVGYGDLVPITPMGRIFTGVIMFIAVSIIAISTGLITSAFSRVWQQENVFAHRHKRD ADKVAAEAGEEEVPK
Specific function: May Play A Role In The Defense Against Osmotic Shock. [C]
COG id: COG1226
COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 cyclic nucleotide-binding domain [H]
Homologues:
Organism=Homo sapiens, GI27436984, Length=193, Percent_Identity=30.5699481865285, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI27436986, Length=193, Percent_Identity=30.5699481865285, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI9789987, Length=193, Percent_Identity=31.0880829015544, Blast_Score=89, Evalue=6e-18, Organism=Homo sapiens, GI27436974, Length=232, Percent_Identity=27.5862068965517, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI4826782, Length=211, Percent_Identity=34.1232227488152, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI4504817, Length=213, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI4826784, Length=232, Percent_Identity=26.2931034482759, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI25952087, Length=227, Percent_Identity=30.8370044052863, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI236462242, Length=241, Percent_Identity=24.896265560166, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI236462079, Length=241, Percent_Identity=24.896265560166, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI236461942, Length=241, Percent_Identity=24.896265560166, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI236461719, Length=241, Percent_Identity=24.896265560166, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI28373065, Length=241, Percent_Identity=24.896265560166, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI27436981, Length=193, Percent_Identity=27.979274611399, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI25952092, Length=229, Percent_Identity=31.0043668122271, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI88758565, Length=206, Percent_Identity=31.5533980582524, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI20070166, Length=254, Percent_Identity=26.3779527559055, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI5031819, Length=150, Percent_Identity=37.3333333333333, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI32479527, Length=200, Percent_Identity=29.5, Blast_Score=80, Evalue=3e-15, Organism=Homo sapiens, GI119395748, Length=265, Percent_Identity=27.5471698113208, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI32479525, Length=203, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI4504821, Length=217, Percent_Identity=30.4147465437788, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI26638655, Length=233, Percent_Identity=26.6094420600858, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI26638653, Length=233, Percent_Identity=26.6094420600858, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI26051262, Length=137, Percent_Identity=30.6569343065693, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI26051260, Length=137, Percent_Identity=30.6569343065693, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI26051266, Length=137, Percent_Identity=30.6569343065693, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI26051264, Length=137, Percent_Identity=30.6569343065693, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI26051268, Length=137, Percent_Identity=30.6569343065693, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4758630, Length=176, Percent_Identity=30.6818181818182, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI19424136, Length=209, Percent_Identity=24.8803827751196, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI25952108, Length=214, Percent_Identity=24.2990654205607, Blast_Score=65, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17544122, Length=193, Percent_Identity=32.1243523316062, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI71998749, Length=208, Percent_Identity=32.6923076923077, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI32564074, Length=208, Percent_Identity=32.6923076923077, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI115532628, Length=209, Percent_Identity=32.5358851674641, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI32564070, Length=208, Percent_Identity=32.6923076923077, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI32564068, Length=208, Percent_Identity=32.6923076923077, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI32564072, Length=208, Percent_Identity=32.6923076923077, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI71994134, Length=183, Percent_Identity=30.6010928961749, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI32564066, Length=234, Percent_Identity=25.6410256410256, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI71989381, Length=207, Percent_Identity=27.0531400966184, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI71989376, Length=207, Percent_Identity=27.0531400966184, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI71989361, Length=207, Percent_Identity=27.0531400966184, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI71989369, Length=207, Percent_Identity=27.0531400966184, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI71994313, Length=220, Percent_Identity=24.5454545454545, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI25147242, Length=241, Percent_Identity=26.5560165975104, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI25147238, Length=241, Percent_Identity=26.5560165975104, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI71986003, Length=232, Percent_Identity=25.8620689655172, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI71986008, Length=232, Percent_Identity=25.8620689655172, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI193206869, Length=184, Percent_Identity=26.6304347826087, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI25148255, Length=184, Percent_Identity=25.5434782608696, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI71994320, Length=206, Percent_Identity=25.7281553398058, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI71986011, Length=214, Percent_Identity=26.1682242990654, Blast_Score=67, Evalue=7e-12, Organism=Drosophila melanogaster, GI24656289, Length=214, Percent_Identity=29.9065420560748, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24656294, Length=214, Percent_Identity=29.9065420560748, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI161084970, Length=193, Percent_Identity=30.0518134715026, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI17737641, Length=193, Percent_Identity=31.0880829015544, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI281365536, Length=232, Percent_Identity=28.0172413793103, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI116007764, Length=232, Percent_Identity=28.0172413793103, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI221330117, Length=168, Percent_Identity=30.3571428571429, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI221330119, Length=168, Percent_Identity=30.3571428571429, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI281363095, Length=168, Percent_Identity=30.3571428571429, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI281363097, Length=168, Percent_Identity=30.3571428571429, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24642914, Length=207, Percent_Identity=28.5024154589372, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24642916, Length=207, Percent_Identity=28.5024154589372, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI45555859, Length=137, Percent_Identity=35.7664233576642, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI45549143, Length=137, Percent_Identity=35.7664233576642, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI24642910, Length=223, Percent_Identity=26.9058295964126, Blast_Score=71, Evalue=8e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR018490 - InterPro: IPR018488 - InterPro: IPR000595 - InterPro: IPR005821 - InterPro: IPR003091 - InterPro: IPR014710 [H]
Pfam domain/function: PF00027 cNMP_binding; PF00520 Ion_trans [H]
EC number: NA
Molecular weight: Translated: 29328; Mature: 29197
Theoretical pI: Translated: 8.96; Mature: 8.96
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPQITRTKLGAANFGPWENIVRVLILVWFMLYTLNAIPDIHPLVGRIAAKVNYWISYFFM CCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH FEYILRVLCAKPRKAYIFSGMGILDFIVCVPFLGMFFGTDWQILYSLRIVRILAIFKLAR HHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH FNETAASFKKAFYLIRDEFFLFFSVILFMLYVTSLGIYIAEHDAQPEKFGSFFDALWFAV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH ETLSTVGYGDLVPITPMGRIFTGVIMFIAVSIIAISTGLITSAFSRVWQQENVFAHRHKR HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH DADKVAAEAGEEEVPK HHHHHHHHCCCCCCCC >Mature Secondary Structure PQITRTKLGAANFGPWENIVRVLILVWFMLYTLNAIPDIHPLVGRIAAKVNYWISYFFM CCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH FEYILRVLCAKPRKAYIFSGMGILDFIVCVPFLGMFFGTDWQILYSLRIVRILAIFKLAR HHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH FNETAASFKKAFYLIRDEFFLFFSVILFMLYVTSLGIYIAEHDAQPEKFGSFFDALWFAV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH ETLSTVGYGDLVPITPMGRIFTGVIMFIAVSIIAISTGLITSAFSRVWQQENVFAHRHKR HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH DADKVAAEAGEEEVPK HHHHHHHHCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: K (I) [Periplasm] [C]
Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 1522059 [H]