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The map label for this gene is lspA [H]

Identifier: 187734703

GI number: 187734703

Start: 240419

End: 241192

Strand: Direct

Name: lspA [H]

Synonym: Amuc_0190

Alternate gene names: 187734703

Gene position: 240419-241192 (Clockwise)

Preceding gene: 187734702

Following gene: 187734704

Centisome position: 9.02

GC content: 57.36

Gene sequence:

>774_bases
ATGGACCCCCAGACGGAAAAAGAACCCGCCCCCCATAAAAAGACGCCTCCCGGCTGGCTCTGGTGGAGCTTGCTGGGCGC
AGGGCTGTATGTGCTGGACCAGGCCAGCAAGCTGTGGATTATCCGCCGCTTCCCGCTGAACTACCTGAACGAAAAGCACC
ATAAGTACGCCTACCTGCCGGACTTTCCGGGCTTCTCTCACATCAATGCGGACGGCACGCTGGACTTCGCCACGAACGGG
CGCATGCCGGAAGCGGAACTGGCGAGGCTCCCGGATCTGAATCCAAACACGGTGGACGCCCTGAACAAACTGAGGGAACT
GGAACCCATCTCCTTTCTGGACGGAACCATGAACATTACCCGCGTGCACAACACGGGCGTTGCCTTCGGGCTGGGGAACG
GCACCGTCTGGTCCAGCTATCTTTTCCTGGCAGTTCCCGTGCTCGCCATCGTAGTCCTGGTCGTGCTTTACCGGAAAAAC
CTCTTCCACACGGCATGGCTCAAGCTGGCCTATGTCCTGCTGCTGGCGGGCGTAGCCGGCAACCTGACGGACCGACTGAT
TCAGGGGTTCCTGATTCCGTATGAGCAACAGCACGGTTTCTTCACCAAGCTGATGAACGGTTACGTGGTGGACTTCATTG
ACGTCACCATCCCCCTCTTCAACTACCGCTGGCCCGCCTTCAATGTGGCGGACTCCTGCATCTTCGTAGCGGCAATTATT
TTCTTCGTCGCCAGCATTTTCTCCGCCAAGAATAAAGAAGAAAAAACATCCTGA

Upstream 100 bases:

>100_bases
CTGCCGCCGGTATGAACCGGCGGCGGAAGGCGGAGACGTATGCGAACGCTGCGCGGAAGTTCTTTCCTGAACCGCATCCA
CTCCATTTCCCGACCTTTAT

Downstream 100 bases:

>100_bases
AACGCCCATGACCACCCGGCTCGTTATTCTGTCAGGACTGCTTTTGTGCGGAAGCCTCGCCTCCGGCAAAAATGAATTGT
CCTTCAAGGAAACGGTGGTT

Product: peptidase A8 signal peptidase II

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MDPQTEKEPAPHKKTPPGWLWWSLLGAGLYVLDQASKLWIIRRFPLNYLNEKHHKYAYLPDFPGFSHINADGTLDFATNG
RMPEAELARLPDLNPNTVDALNKLRELEPISFLDGTMNITRVHNTGVAFGLGNGTVWSSYLFLAVPVLAIVVLVVLYRKN
LFHTAWLKLAYVLLLAGVAGNLTDRLIQGFLIPYEQQHGFFTKLMNGYVVDFIDVTIPLFNYRWPAFNVADSCIFVAAII
FFVASIFSAKNKEEKTS

Sequences:

>Translated_257_residues
MDPQTEKEPAPHKKTPPGWLWWSLLGAGLYVLDQASKLWIIRRFPLNYLNEKHHKYAYLPDFPGFSHINADGTLDFATNG
RMPEAELARLPDLNPNTVDALNKLRELEPISFLDGTMNITRVHNTGVAFGLGNGTVWSSYLFLAVPVLAIVVLVVLYRKN
LFHTAWLKLAYVLLLAGVAGNLTDRLIQGFLIPYEQQHGFFTKLMNGYVVDFIDVTIPLFNYRWPAFNVADSCIFVAAII
FFVASIFSAKNKEEKTS
>Mature_257_residues
MDPQTEKEPAPHKKTPPGWLWWSLLGAGLYVLDQASKLWIIRRFPLNYLNEKHHKYAYLPDFPGFSHINADGTLDFATNG
RMPEAELARLPDLNPNTVDALNKLRELEPISFLDGTMNITRVHNTGVAFGLGNGTVWSSYLFLAVPVLAIVVLVVLYRKN
LFHTAWLKLAYVLLLAGVAGNLTDRLIQGFLIPYEQQHGFFTKLMNGYVVDFIDVTIPLFNYRWPAFNVADSCIFVAAII
FFVASIFSAKNKEEKTS

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 29033; Mature: 29033

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPQTEKEPAPHKKTPPGWLWWSLLGAGLYVLDQASKLWIIRRFPLNYLNEKHHKYAYLP
CCCCCCCCCCCCCCCCCHHHHHHHHHCCHHEEECCCCEEEEEECCHHHHCCCCCCEEECC
DFPGFSHINADGTLDFATNGRMPEAELARLPDLNPNTVDALNKLRELEPISFLDGTMNIT
CCCCCCEECCCCEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHCCCCEEE
RVHNTGVAFGLGNGTVWSSYLFLAVPVLAIVVLVVLYRKNLFHTAWLKLAYVLLLAGVAG
EEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NLTDRLIQGFLIPYEQQHGFFTKLMNGYVVDFIDVTIPLFNYRWPAFNVADSCIFVAAII
HHHHHHHHHHCCCCHHCCCHHHHHHCCHHEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
FFVASIFSAKNKEEKTS
HHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDPQTEKEPAPHKKTPPGWLWWSLLGAGLYVLDQASKLWIIRRFPLNYLNEKHHKYAYLP
CCCCCCCCCCCCCCCCCHHHHHHHHHCCHHEEECCCCEEEEEECCHHHHCCCCCCEEECC
DFPGFSHINADGTLDFATNGRMPEAELARLPDLNPNTVDALNKLRELEPISFLDGTMNIT
CCCCCCEECCCCEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHCCCCEEE
RVHNTGVAFGLGNGTVWSSYLFLAVPVLAIVVLVVLYRKNLFHTAWLKLAYVLLLAGVAG
EEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NLTDRLIQGFLIPYEQQHGFFTKLMNGYVVDFIDVTIPLFNYRWPAFNVADSCIFVAAII
HHHHHHHHHHCCCCHHCCCHHHHHHCCHHEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
FFVASIFSAKNKEEKTS
HHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA