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The map label for this gene is macB [H]

Identifier: 187734618

GI number: 187734618

Start: 128919

End: 130283

Strand: Direct

Name: macB [H]

Synonym: Amuc_0104

Alternate gene names: 187734618

Gene position: 128919-130283 (Clockwise)

Preceding gene: 187734617

Following gene: 187734619

Centisome position: 4.84

GC content: 59.27

Gene sequence:

>1365_bases
ATGAAATTCCTTCCTCTCCTTAAAACCTGCATCAGGGCCCTGGTGCGCAATCCCATGCGCGCAGCCCTCACCATCCTGGG
CATCATCATCGGCATTGCCGCAGTAATCGCCATGGTGGAAATCGGCCAGGGATCTACGCTCCAGATTAAAAATACCATCG
CTTCCATGGGGGCGGACACGCTGAATATCCGCCCCGGAGCCATCTCCAAAAGCGGCGTCAATACCGGCGCGGGCGGACGG
GCCTCCCTGACCAACGCAGACTGCGAAGCCATTGCGAAGGACTGCCCCATGGTTCTGCGGGCTACCCCCGTGGTGCGCGC
CAGCGGCCAAGTCATTTACGGCAACAAGAACTGGAGCCCGGAAACTGTAGAGGGCGGTTCCGTGGAATACCTGAAAATCA
AAAGCTGGTATGACATGGCGCGAGGCCAGCCCTTCTCCGAGGAAGATGTGGAACAGGCCAGGCGCGTGTGCGTCATTGGC
CAGACGGTGGCCAAGGAACTTTTCGGGGACGAAGACCCGCTGGGCAAGGATATCCGCATCAAGAATGTCATGTTCAAAGT
CATCGGCATCCTTCAGAAAAAAGGGGCCAACATGATGGGACGCGACCAGGACGACTCCATCATCCTCCCGTGGACAAGCA
TCCGCTACCGCCTCCAGGGCCTGGGCGGCGGTTCCACCACCACTTCCACCGGCAACAGCACCACCACCTTCAACCGGGCA
GATAAATACACCGCCAGTTCCGTGGATTACTACACGGAAACTACGGACCAGCCCTATACGGACGCGCCCCATCCGCGGCG
CTTCAACAATATTGATTCCATCATGGCTCAGATTTCAGACCCGGAACGCTCCTCCGAGGCCATTGACCAGATTACGGAAG
TGATCCGTGCCAAACACAACCTCAAGGACGGCCAGCTGGACGATTTCCGGGTATGGGACATGGCGGAAATGTCCCGCGCC
ATGAGCAGCACCACGGAAGTGATGACCAATCTGCTGATGATCGTGGCCATGATCTCTCTGGTCGTCGGCGGCGTCGGCAT
CATGAATATCATGCTCGTTTCCGTCACGGAACGGACCAAGGAAATTGGCCTGCGCATGGCGGTGGGCGCCCGTCCGCAGG
ATATCATGCGCCAGTTCCTGCTGGAAGCGGTGCTGCTCTGCGTGGTGGGCGGCGCGCTGGGCATCATGCTCGGCAAGGCG
ATCTCCATCATCGTCAGCCGCACCATGAACTGGGCCACGGCCTCCTCCCCGGAAGCCATGGCTCTGGCTGTAGGCGTCTC
CGTATTCATCGGCCTGGCCTTCGGATGGTACCCCTCCTGGAAGGCGTCCAAGATGGACCCCATTGATGCCCTTCGCCACG
AATAA

Upstream 100 bases:

>100_bases
CGCACGACCCCAAAATAGCCGCCTTCACGGACAGGGCCATCAACATGGCGGACGGCCTTATCTGCGAAGGGATTTCCGAT
ATGCTTAGCAAGGACGACGT

Downstream 100 bases:

>100_bases
CACCTTACTTTTTATTTTTCCATGTCATCCACGTTCAAACATCTCCCCCTTCTGGCCGCCTGTTTCCTTGGCTCCTGCAT
GGTAGGCCCTGATTTCCGGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MKFLPLLKTCIRALVRNPMRAALTILGIIIGIAAVIAMVEIGQGSTLQIKNTIASMGADTLNIRPGAISKSGVNTGAGGR
ASLTNADCEAIAKDCPMVLRATPVVRASGQVIYGNKNWSPETVEGGSVEYLKIKSWYDMARGQPFSEEDVEQARRVCVIG
QTVAKELFGDEDPLGKDIRIKNVMFKVIGILQKKGANMMGRDQDDSIILPWTSIRYRLQGLGGGSTTTSTGNSTTTFNRA
DKYTASSVDYYTETTDQPYTDAPHPRRFNNIDSIMAQISDPERSSEAIDQITEVIRAKHNLKDGQLDDFRVWDMAEMSRA
MSSTTEVMTNLLMIVAMISLVVGGVGIMNIMLVSVTERTKEIGLRMAVGARPQDIMRQFLLEAVLLCVVGGALGIMLGKA
ISIIVSRTMNWATASSPEAMALAVGVSVFIGLAFGWYPSWKASKMDPIDALRHE

Sequences:

>Translated_454_residues
MKFLPLLKTCIRALVRNPMRAALTILGIIIGIAAVIAMVEIGQGSTLQIKNTIASMGADTLNIRPGAISKSGVNTGAGGR
ASLTNADCEAIAKDCPMVLRATPVVRASGQVIYGNKNWSPETVEGGSVEYLKIKSWYDMARGQPFSEEDVEQARRVCVIG
QTVAKELFGDEDPLGKDIRIKNVMFKVIGILQKKGANMMGRDQDDSIILPWTSIRYRLQGLGGGSTTTSTGNSTTTFNRA
DKYTASSVDYYTETTDQPYTDAPHPRRFNNIDSIMAQISDPERSSEAIDQITEVIRAKHNLKDGQLDDFRVWDMAEMSRA
MSSTTEVMTNLLMIVAMISLVVGGVGIMNIMLVSVTERTKEIGLRMAVGARPQDIMRQFLLEAVLLCVVGGALGIMLGKA
ISIIVSRTMNWATASSPEAMALAVGVSVFIGLAFGWYPSWKASKMDPIDALRHE
>Mature_454_residues
MKFLPLLKTCIRALVRNPMRAALTILGIIIGIAAVIAMVEIGQGSTLQIKNTIASMGADTLNIRPGAISKSGVNTGAGGR
ASLTNADCEAIAKDCPMVLRATPVVRASGQVIYGNKNWSPETVEGGSVEYLKIKSWYDMARGQPFSEEDVEQARRVCVIG
QTVAKELFGDEDPLGKDIRIKNVMFKVIGILQKKGANMMGRDQDDSIILPWTSIRYRLQGLGGGSTTTSTGNSTTTFNRA
DKYTASSVDYYTETTDQPYTDAPHPRRFNNIDSIMAQISDPERSSEAIDQITEVIRAKHNLKDGQLDDFRVWDMAEMSRA
MSSTTEVMTNLLMIVAMISLVVGGVGIMNIMLVSVTERTKEIGLRMAVGARPQDIMRQFLLEAVLLCVVGGALGIMLGKA
ISIIVSRTMNWATASSPEAMALAVGVSVFIGLAFGWYPSWKASKMDPIDALRHE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=456, Percent_Identity=33.5526315789474, Blast_Score=206, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 49311; Mature: 49311

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLPLLKTCIRALVRNPMRAALTILGIIIGIAAVIAMVEIGQGSTLQIKNTIASMGADT
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCE
LNIRPGAISKSGVNTGAGGRASLTNADCEAIAKDCPMVLRATPVVRASGQVIYGNKNWSP
EECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHCCCCEEEECCEEEECCCCCCC
ETVEGGSVEYLKIKSWYDMARGQPFSEEDVEQARRVCVIGQTVAKELFGDEDPLGKDIRI
CCCCCCCEEEEEEHHHHHHHCCCCCCHHHHHHHHHEEHHHHHHHHHHCCCCCCCCCCCHH
KNVMFKVIGILQKKGANMMGRDQDDSIILPWTSIRYRLQGLGGGSTTTSTGNSTTTFNRA
HHHHHHHHHHHHHCCCCCCCCCCCCCEEECHHHHHHEEEECCCCCCCCCCCCCCCCCCCC
DKYTASSVDYYTETTDQPYTDAPHPRRFNNIDSIMAQISDPERSSEAIDQITEVIRAKHN
CCCCCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
LKDGQLDDFRVWDMAEMSRAMSSTTEVMTNLLMIVAMISLVVGGVGIMNIMLVSVTERTK
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
EIGLRMAVGARPQDIMRQFLLEAVLLCVVGGALGIMLGKAISIIVSRTMNWATASSPEAM
HCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
ALAVGVSVFIGLAFGWYPSWKASKMDPIDALRHE
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MKFLPLLKTCIRALVRNPMRAALTILGIIIGIAAVIAMVEIGQGSTLQIKNTIASMGADT
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCE
LNIRPGAISKSGVNTGAGGRASLTNADCEAIAKDCPMVLRATPVVRASGQVIYGNKNWSP
EECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHCCCCEEEECCEEEECCCCCCC
ETVEGGSVEYLKIKSWYDMARGQPFSEEDVEQARRVCVIGQTVAKELFGDEDPLGKDIRI
CCCCCCCEEEEEEHHHHHHHCCCCCCHHHHHHHHHEEHHHHHHHHHHCCCCCCCCCCCHH
KNVMFKVIGILQKKGANMMGRDQDDSIILPWTSIRYRLQGLGGGSTTTSTGNSTTTFNRA
HHHHHHHHHHHHHCCCCCCCCCCCCCEEECHHHHHHEEEECCCCCCCCCCCCCCCCCCCC
DKYTASSVDYYTETTDQPYTDAPHPRRFNNIDSIMAQISDPERSSEAIDQITEVIRAKHN
CCCCCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
LKDGQLDDFRVWDMAEMSRAMSSTTEVMTNLLMIVAMISLVVGGVGIMNIMLVSVTERTK
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
EIGLRMAVGARPQDIMRQFLLEAVLLCVVGGALGIMLGKAISIIVSRTMNWATASSPEAM
HCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
ALAVGVSVFIGLAFGWYPSWKASKMDPIDALRHE
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA