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The map label for this gene is clpB [H]

Identifier: 187734574

GI number: 187734574

Start: 77975

End: 80557

Strand: Direct

Name: clpB [H]

Synonym: Amuc_0059

Alternate gene names: 187734574

Gene position: 77975-80557 (Clockwise)

Preceding gene: 187734573

Following gene: 187734575

Centisome position: 2.93

GC content: 59.81

Gene sequence:

>2583_bases
ATGAATAATTTTACGCCTAGGGCGCAACAAGTGCTGGCGCATGCGCGCCGGGAAGCGGACCGCTTCAATCATCATTACAT
AGGAACCGAACACCTTCTGCTCGGCCTGCTCAAGCTGGGCAAGGGCGTGGCCGTCACCATCCTGGAAAATCTGGGCGTGG
AGCTTACCGCCGTGCGCAAACAGGTGGAGGAACAAATAGGCCGGGGCACGGAACCCCAGGCGGAGGGCAACATCCCGTAC
ACCCCCAGGGTGCGCAAAGTCCTGGCAATGGCAAACAGGGAAGCCCAGGAACTCAACCACACGTATGTGGGCACGGAACA
CCTGCTCCTGGGCCTCATCCGTGACGGCGACGGCGTGGCCGGACAGATTCTGCGCCACTTCGGCGTGGATTTGGAACAAG
CGCGGCGCGAATTGCTGGACGTGCTGACCCCCAAATACCAGATGGATGCGGATGAAGACAACATCATCCCGGACGACGAT
GACGACGAGGAGGAAAATGAATCCCCCGCCATCCCGACGGACGAGCCTTCCTCCCCCTCCTACTCCAGGCAGCAGAAATC
CAAGACACCCGCGCTCCAGGCCTTTGGCCGGGACATGACCCAGCTGGCCCGGGACGGCAAGCTGGATCCCGTCATCGGCC
GCGCCTCGGAAATTGAGCGCGTCATCCAGATTCTGTGCCGGAGGAACAAAAACAACCCCGTCCTGCTCGGTGAAGCCGGG
GTGGGCAAAACCGCCATCGTGGAAGGGCTGGCCCAGGAAATAGCCCAGGGCCATGTTCCGGAGCTCCTGCGCAGCAAGAG
GGTCATCTCCCTGGACCTGGCGCTGATGGTGGCTGGCACCAAATACCGCGGTCAGTTTGAGGAACGGCTTAAGGCCGTAA
TGGATGAAATACGCCGGGAAGGCAATGTCATCCTTTTCATTGATGAACTGCACACCATCGTAGGCGCCGGCTCCGCGGAA
GGCTCCATGGACGCCTCCAACATCATCAAGCCCGCCCTCTCCCGGGGTGAGCTCCAGGCCATAGGCGCCACCACGCTCAA
CGAATACAGGAAACACATTGAGAAGGACGCCGCCCTGGAACGCCGCTTCCAGCAGGTGCAGGTAGGGGAACCCTCCGTGG
AGGACACCATCCAGATTCTTGCCGGGATCCAGCCCAAGTATGAGGAACATCACAAGGTGCATTATACGAAGGAAGCCGTT
GAAGCCGCAGCCAAGCTCTCCCACCGCTATCTGACGGGCCGGTTCCTGCCGGACAAGGCCATCGACATCCTGGATGAAGC
GGGCGCGCGCAAGCGCGTCTCCCAGATGACCCGCCCGGACCACATCAGCAACATGGAAATCCGCATTGCGGAAATCAAGG
AACGCAAGGACAAGGCTGTGGAAACCCAGCTTTTTGAAGAAGCAGCCCGCCTGCGCGACGAGGAAAAACAAGCCAAGGCG
GAACTTCAGAACATGCTGGAAACCTGGCGCAACTCCTATGAGACCAACTACGTTCCCGTGACGGATGAAGACGTGATGAG
CGTACTCGCCAAATGGACGGGCATCCCGCTGGCCCGGATGGAGGAAAAGGAAACCACCAAGCTTCTGCGGATGGAGGAAG
AGTTGAAAAGCAAAGTCATCGGCCAGGACGAGGCGGCTTCCGCCATCGCCCGCGCTCTGCGGCGCAGCCGTGCGGATATC
AAGGATCCGCGCCGCCCGATCGGCTCATTCCTCTTCCTGGGCCCCACCGGCGTGGGCAAAACCTATCTGGCCCGCAATCT
GGCGGAAATCATGTTCGGTACCTCGGACGCCCTGATTCAGGTGGACATGAGCGAGTACATGGAAAAACACACCACGTCCC
GTCTCATCGGTTCTCCTCCCGGCTATGTAGGCCATGACGAAGGCGGACAGCTCACGGAAGCCGTCCGGCGCAGGCCCTAC
TCCGTCATCCTCTTTGATGAAGTGGAAAAGGCCCATCCGGACGTCATGAACCTGCTTCTCCAGATTTTGGAAGAAGGCAG
CGTAACAGACTCGCTGGGACGCAAGATCAACTTCCGCAACACCATCATCATCCTGACCTCCAATGTGGGGGCCGCTTCCG
CCAAACGGCAGAGCACCATGGGCTTCGGCGCCATGGCCGCCGACAACGCGGACTACGCCGCCATGAAGGAAAAGATTCTG
GAAGCGGCGCGCAAGCAATTCCGGCCGGAATTCCTGAACCGATTTGATGACATTTCTGTCTTCCGCATGCTGGAACGGGA
CGACCTGGAACGCATCGTGCATCTGGAAGCGGACAAGCTCATCTCCCGTCTCAAGACCAAGAATATCACGCTTGCCCTGA
GCCAGGAAGCTCTGAGCCTGATCATCAAGAACGGCTATGACCCGCAGTACGGCGCCCGCCCGATGCGCCGCGCCATCGAA
CGCCTGCTGGAAGACCCGCTGGCGGAATCCCTGCTGAGGGGAGACGTGAAACCCGGCGATAAAATTGAAGCCGTGGAAAC
GGACGGGACGGAGACGCTCACCTTCCTGCACATCAAGGACAAAAAACCAGCCAGGCCCAAAGCGCCGCGCAAGAGAACGC
CGCGGAAACCCAAGGCGGAATAA

Upstream 100 bases:

>100_bases
GACCAAACCACTCCGGAACACAGGGACCAGATCCGCGCTGATATTATTCGGAAAGAACTTTCCGGCAACTAATGCAACCA
AACAATTTTTTTGACCATCC

Downstream 100 bases:

>100_bases
ACGCTTTTAGGCTTTTCAACCAGGGCCCCTGCATGTTGACATGCAGGGGCCTTTTCATTGGGCCGGATTCCGCGGAACTG
CCATTTCCATCCCCTGAAAG

Product: ATPase AAA-2 domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 860; Mature: 860

Protein sequence:

>860_residues
MNNFTPRAQQVLAHARREADRFNHHYIGTEHLLLGLLKLGKGVAVTILENLGVELTAVRKQVEEQIGRGTEPQAEGNIPY
TPRVRKVLAMANREAQELNHTYVGTEHLLLGLIRDGDGVAGQILRHFGVDLEQARRELLDVLTPKYQMDADEDNIIPDDD
DDEEENESPAIPTDEPSSPSYSRQQKSKTPALQAFGRDMTQLARDGKLDPVIGRASEIERVIQILCRRNKNNPVLLGEAG
VGKTAIVEGLAQEIAQGHVPELLRSKRVISLDLALMVAGTKYRGQFEERLKAVMDEIRREGNVILFIDELHTIVGAGSAE
GSMDASNIIKPALSRGELQAIGATTLNEYRKHIEKDAALERRFQQVQVGEPSVEDTIQILAGIQPKYEEHHKVHYTKEAV
EAAAKLSHRYLTGRFLPDKAIDILDEAGARKRVSQMTRPDHISNMEIRIAEIKERKDKAVETQLFEEAARLRDEEKQAKA
ELQNMLETWRNSYETNYVPVTDEDVMSVLAKWTGIPLARMEEKETTKLLRMEEELKSKVIGQDEAASAIARALRRSRADI
KDPRRPIGSFLFLGPTGVGKTYLARNLAEIMFGTSDALIQVDMSEYMEKHTTSRLIGSPPGYVGHDEGGQLTEAVRRRPY
SVILFDEVEKAHPDVMNLLLQILEEGSVTDSLGRKINFRNTIIILTSNVGAASAKRQSTMGFGAMAADNADYAAMKEKIL
EAARKQFRPEFLNRFDDISVFRMLERDDLERIVHLEADKLISRLKTKNITLALSQEALSLIIKNGYDPQYGARPMRRAIE
RLLEDPLAESLLRGDVKPGDKIEAVETDGTETLTFLHIKDKKPARPKAPRKRTPRKPKAE

Sequences:

>Translated_860_residues
MNNFTPRAQQVLAHARREADRFNHHYIGTEHLLLGLLKLGKGVAVTILENLGVELTAVRKQVEEQIGRGTEPQAEGNIPY
TPRVRKVLAMANREAQELNHTYVGTEHLLLGLIRDGDGVAGQILRHFGVDLEQARRELLDVLTPKYQMDADEDNIIPDDD
DDEEENESPAIPTDEPSSPSYSRQQKSKTPALQAFGRDMTQLARDGKLDPVIGRASEIERVIQILCRRNKNNPVLLGEAG
VGKTAIVEGLAQEIAQGHVPELLRSKRVISLDLALMVAGTKYRGQFEERLKAVMDEIRREGNVILFIDELHTIVGAGSAE
GSMDASNIIKPALSRGELQAIGATTLNEYRKHIEKDAALERRFQQVQVGEPSVEDTIQILAGIQPKYEEHHKVHYTKEAV
EAAAKLSHRYLTGRFLPDKAIDILDEAGARKRVSQMTRPDHISNMEIRIAEIKERKDKAVETQLFEEAARLRDEEKQAKA
ELQNMLETWRNSYETNYVPVTDEDVMSVLAKWTGIPLARMEEKETTKLLRMEEELKSKVIGQDEAASAIARALRRSRADI
KDPRRPIGSFLFLGPTGVGKTYLARNLAEIMFGTSDALIQVDMSEYMEKHTTSRLIGSPPGYVGHDEGGQLTEAVRRRPY
SVILFDEVEKAHPDVMNLLLQILEEGSVTDSLGRKINFRNTIIILTSNVGAASAKRQSTMGFGAMAADNADYAAMKEKIL
EAARKQFRPEFLNRFDDISVFRMLERDDLERIVHLEADKLISRLKTKNITLALSQEALSLIIKNGYDPQYGARPMRRAIE
RLLEDPLAESLLRGDVKPGDKIEAVETDGTETLTFLHIKDKKPARPKAPRKRTPRKPKAE
>Mature_860_residues
MNNFTPRAQQVLAHARREADRFNHHYIGTEHLLLGLLKLGKGVAVTILENLGVELTAVRKQVEEQIGRGTEPQAEGNIPY
TPRVRKVLAMANREAQELNHTYVGTEHLLLGLIRDGDGVAGQILRHFGVDLEQARRELLDVLTPKYQMDADEDNIIPDDD
DDEEENESPAIPTDEPSSPSYSRQQKSKTPALQAFGRDMTQLARDGKLDPVIGRASEIERVIQILCRRNKNNPVLLGEAG
VGKTAIVEGLAQEIAQGHVPELLRSKRVISLDLALMVAGTKYRGQFEERLKAVMDEIRREGNVILFIDELHTIVGAGSAE
GSMDASNIIKPALSRGELQAIGATTLNEYRKHIEKDAALERRFQQVQVGEPSVEDTIQILAGIQPKYEEHHKVHYTKEAV
EAAAKLSHRYLTGRFLPDKAIDILDEAGARKRVSQMTRPDHISNMEIRIAEIKERKDKAVETQLFEEAARLRDEEKQAKA
ELQNMLETWRNSYETNYVPVTDEDVMSVLAKWTGIPLARMEEKETTKLLRMEEELKSKVIGQDEAASAIARALRRSRADI
KDPRRPIGSFLFLGPTGVGKTYLARNLAEIMFGTSDALIQVDMSEYMEKHTTSRLIGSPPGYVGHDEGGQLTEAVRRRPY
SVILFDEVEKAHPDVMNLLLQILEEGSVTDSLGRKINFRNTIIILTSNVGAASAKRQSTMGFGAMAADNADYAAMKEKIL
EAARKQFRPEFLNRFDDISVFRMLERDDLERIVHLEADKLISRLKTKNITLALSQEALSLIIKNGYDPQYGARPMRRAIE
RLLEDPLAESLLRGDVKPGDKIEAVETDGTETLTFLHIKDKKPARPKAPRKRTPRKPKAE

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=310, Percent_Identity=36.7741935483871, Blast_Score=189, Evalue=8e-48,
Organism=Escherichia coli, GI1788943, Length=887, Percent_Identity=43.630214205186, Blast_Score=691, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=820, Percent_Identity=39.2682926829268, Blast_Score=538, Evalue=1e-154,
Organism=Saccharomyces cerevisiae, GI6320464, Length=708, Percent_Identity=46.1864406779661, Blast_Score=594, Evalue=1e-170,
Organism=Saccharomyces cerevisiae, GI6323002, Length=905, Percent_Identity=36.4640883977901, Blast_Score=505, Evalue=1e-143,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 96514; Mature: 96514

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNFTPRAQQVLAHARREADRFNHHYIGTEHLLLGLLKLGKGVAVTILENLGVELTAVRK
CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEHHHHCCCHHHHHHH
QVEEQIGRGTEPQAEGNIPYTPRVRKVLAMANREAQELNHTYVGTEHLLLGLIRDGDGVA
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHCCCCCHH
GQILRHFGVDLEQARRELLDVLTPKYQMDADEDNIIPDDDDDEEENESPAIPTDEPSSPS
HHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
YSRQQKSKTPALQAFGRDMTQLARDGKLDPVIGRASEIERVIQILCRRNKNNPVLLGEAG
HHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCC
VGKTAIVEGLAQEIAQGHVPELLRSKRVISLDLALMVAGTKYRGQFEERLKAVMDEIRRE
CCHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHC
GNVILFIDELHTIVGAGSAEGSMDASNIIKPALSRGELQAIGATTLNEYRKHIEKDAALE
CCEEEEEHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RRFQQVQVGEPSVEDTIQILAGIQPKYEEHHKVHYTKEAVEAAAKLSHRYLTGRFLPDKA
HHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
IDILDEAGARKRVSQMTRPDHISNMEIRIAEIKERKDKAVETQLFEEAARLRDEEKQAKA
HHHHHHCCHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ELQNMLETWRNSYETNYVPVTDEDVMSVLAKWTGIPLARMEEKETTKLLRMEEELKSKVI
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHC
GQDEAASAIARALRRSRADIKDPRRPIGSFLFLGPTGVGKTYLARNLAEIMFGTSDALIQ
CCHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEECCCCCCHHHHHHHHHHHHHCCCHHEEE
VDMSEYMEKHTTSRLIGSPPGYVGHDEGGQLTEAVRRRPYSVILFDEVEKAHPDVMNLLL
ECHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCHHHCCHHHHHHHH
QILEEGSVTDSLGRKINFRNTIIILTSNVGAASAKRQSTMGFGAMAADNADYAAMKEKIL
HHHHCCCCCHHHCCEEECCCEEEEEECCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
EAARKQFRPEFLNRFDDISVFRMLERDDLERIVHLEADKLISRLKTKNITLALSQEALSL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHH
IIKNGYDPQYGARPMRRAIERLLEDPLAESLLRGDVKPGDKIEAVETDGTETLTFLHIKD
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEEEC
KKPARPKAPRKRTPRKPKAE
CCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNNFTPRAQQVLAHARREADRFNHHYIGTEHLLLGLLKLGKGVAVTILENLGVELTAVRK
CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEHHHHCCCHHHHHHH
QVEEQIGRGTEPQAEGNIPYTPRVRKVLAMANREAQELNHTYVGTEHLLLGLIRDGDGVA
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHCCCCCHH
GQILRHFGVDLEQARRELLDVLTPKYQMDADEDNIIPDDDDDEEENESPAIPTDEPSSPS
HHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
YSRQQKSKTPALQAFGRDMTQLARDGKLDPVIGRASEIERVIQILCRRNKNNPVLLGEAG
HHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCC
VGKTAIVEGLAQEIAQGHVPELLRSKRVISLDLALMVAGTKYRGQFEERLKAVMDEIRRE
CCHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHC
GNVILFIDELHTIVGAGSAEGSMDASNIIKPALSRGELQAIGATTLNEYRKHIEKDAALE
CCEEEEEHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RRFQQVQVGEPSVEDTIQILAGIQPKYEEHHKVHYTKEAVEAAAKLSHRYLTGRFLPDKA
HHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
IDILDEAGARKRVSQMTRPDHISNMEIRIAEIKERKDKAVETQLFEEAARLRDEEKQAKA
HHHHHHCCHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ELQNMLETWRNSYETNYVPVTDEDVMSVLAKWTGIPLARMEEKETTKLLRMEEELKSKVI
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHC
GQDEAASAIARALRRSRADIKDPRRPIGSFLFLGPTGVGKTYLARNLAEIMFGTSDALIQ
CCHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEECCCCCCHHHHHHHHHHHHHCCCHHEEE
VDMSEYMEKHTTSRLIGSPPGYVGHDEGGQLTEAVRRRPYSVILFDEVEKAHPDVMNLLL
ECHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCHHHCCHHHHHHHH
QILEEGSVTDSLGRKINFRNTIIILTSNVGAASAKRQSTMGFGAMAADNADYAAMKEKIL
HHHHCCCCCHHHCCEEECCCEEEEEECCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
EAARKQFRPEFLNRFDDISVFRMLERDDLERIVHLEADKLISRLKTKNITLALSQEALSL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHH
IIKNGYDPQYGARPMRRAIERLLEDPLAESLLRGDVKPGDKIEAVETDGTETLTFLHIKD
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEEEC
KKPARPKAPRKRTPRKPKAE
CCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]