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The map label for this gene is pheA [H]

Identifier: 187734525

GI number: 187734525

Start: 11054

End: 12211

Strand: Direct

Name: pheA [H]

Synonym: Amuc_0009

Alternate gene names: 187734525

Gene position: 11054-12211 (Clockwise)

Preceding gene: 187734524

Following gene: 187734526

Centisome position: 0.41

GC content: 57.43

Gene sequence:

>1158_bases
ATGGAGACCACGCACCACGGGGAGGACGCCTCTCCGGACAATCCCCCCAGGCAGCAAAAAAGCGGAAACACGGATGAACA
GACCATCGCCCTGACAAAGGCGCGTCTGGCCATTGACGAGGTGGACGCCCGGATTGTAGAGCTGTTAAAAAAACGCGCCG
AATGGGTGCATGAAGTCGGCCGCATTAAAAAGGAAAAAAATTCCCCCATCTTCGTTCCCGAACGGGAAACGGCCCTGCTC
AACAAATTGAACCGCCTGAATGCGGGCGTGCTGCCGGAAGCCTCCCTCCAGGCTATTTACCGTGAAATCATTTCCTGCTC
CTTCTTTCTGGAAGGCGGCCTGACCATTGCCTACCTGGGCCCCAAAGGAACCTGGAGCCACCAGGCGGCCCTCAAGCAGT
TCGGAAAAAGTTGCGAACTCATTCCGTGCCAGAGCTTCAAGGACGTATTTGACATGGTGGACCGGGGGAAGGCCCAGTAC
GGCGTAGTTCCCGTGGAAAACTCTTCGGAAGGTTCCGTCACCGCCGTGATGGATCTTTTCGTCACCTCTCCCCTCAAAAT
CTGCGCCCAAATCAATCTGAACATCCGCAACAGCCTGATGGCGGATATTCCGCGGGAACACATCCGCATCCTGTATTCCC
ACCCCCAGGTTCTCGGCCAGACGCGGAACTGGATCCAGCGGCATTTCCCAAACGCGGAACTCGTGGAAACGTCCTCCACC
ACGAAAGCCAGCATTCTTGCCAAGGAGAACGCCGCCATGGGCGCGGCATCCCTCGGCTGTCCGCTGGCCGCGGAATTGTT
CGGCCTGAACATCCTGGAAGAAGACGTGCAGGACCAGTCCTGCAACACCACCCGTTTTGCCGTCATCGGACGCCAGGAAA
CGCAGCCCAGCGGCAGGGACCGCACCTCCCTGCTCATCCGCATCCAGCATAAACCCGGCACCCTGGCGGAAGTAGTCAAC
TGCTTCCAGCGGCACAACAATAACCTGATACGCATTGAATCCCGCCCGTCCAAAGTCATCAACTGGGAATACGTCTTTTA
CATAGATGCCGCCGGCCACATTCAGGAATCCCCCTTACGGGAAACCCTTCCGGAGCTGGAGCAGCACTGCTCCATGCTGA
AGATTCTGGGCAGCTACGCGGATACGGACGTCATTTAA

Upstream 100 bases:

>100_bases
GCAAGAAGAATCCGCGGCGGAGACCTCCCCTTTAATCTTGATTTGCCCCCCCGGAACCGCTACCCTGACACGGCTTTAAC
CACACAGCTTTCACAGAGAC

Downstream 100 bases:

>100_bases
GCAGGTTCAGCCTTCCCCCCCAGCCTCACACCATTCTGAACAACCATGAACATAGCCACGATTGCCGCCCTGGCCGTCAC
TCTGGGACTTCCCGCCCCGG

Product: chorismate mutase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
METTHHGEDASPDNPPRQQKSGNTDEQTIALTKARLAIDEVDARIVELLKKRAEWVHEVGRIKKEKNSPIFVPERETALL
NKLNRLNAGVLPEASLQAIYREIISCSFFLEGGLTIAYLGPKGTWSHQAALKQFGKSCELIPCQSFKDVFDMVDRGKAQY
GVVPVENSSEGSVTAVMDLFVTSPLKICAQINLNIRNSLMADIPREHIRILYSHPQVLGQTRNWIQRHFPNAELVETSST
TKASILAKENAAMGAASLGCPLAAELFGLNILEEDVQDQSCNTTRFAVIGRQETQPSGRDRTSLLIRIQHKPGTLAEVVN
CFQRHNNNLIRIESRPSKVINWEYVFYIDAAGHIQESPLRETLPELEQHCSMLKILGSYADTDVI

Sequences:

>Translated_385_residues
METTHHGEDASPDNPPRQQKSGNTDEQTIALTKARLAIDEVDARIVELLKKRAEWVHEVGRIKKEKNSPIFVPERETALL
NKLNRLNAGVLPEASLQAIYREIISCSFFLEGGLTIAYLGPKGTWSHQAALKQFGKSCELIPCQSFKDVFDMVDRGKAQY
GVVPVENSSEGSVTAVMDLFVTSPLKICAQINLNIRNSLMADIPREHIRILYSHPQVLGQTRNWIQRHFPNAELVETSST
TKASILAKENAAMGAASLGCPLAAELFGLNILEEDVQDQSCNTTRFAVIGRQETQPSGRDRTSLLIRIQHKPGTLAEVVN
CFQRHNNNLIRIESRPSKVINWEYVFYIDAAGHIQESPLRETLPELEQHCSMLKILGSYADTDVI
>Mature_385_residues
METTHHGEDASPDNPPRQQKSGNTDEQTIALTKARLAIDEVDARIVELLKKRAEWVHEVGRIKKEKNSPIFVPERETALL
NKLNRLNAGVLPEASLQAIYREIISCSFFLEGGLTIAYLGPKGTWSHQAALKQFGKSCELIPCQSFKDVFDMVDRGKAQY
GVVPVENSSEGSVTAVMDLFVTSPLKICAQINLNIRNSLMADIPREHIRILYSHPQVLGQTRNWIQRHFPNAELVETSST
TKASILAKENAAMGAASLGCPLAAELFGLNILEEDVQDQSCNTTRFAVIGRQETQPSGRDRTSLLIRIQHKPGTLAEVVN
CFQRHNNNLIRIESRPSKVINWEYVFYIDAAGHIQESPLRETLPELEQHCSMLKILGSYADTDVI

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=376, Percent_Identity=30.5851063829787, Blast_Score=170, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6324013, Length=304, Percent_Identity=28.2894736842105, Blast_Score=107, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 42978; Mature: 42978

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METTHHGEDASPDNPPRQQKSGNTDEQTIALTKARLAIDEVDARIVELLKKRAEWVHEVG
CCCCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIKKEKNSPIFVPERETALLNKLNRLNAGVLPEASLQAIYREIISCSFFLEGGLTIAYLG
HHHHHCCCCEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEECCCEEEEEC
PKGTWSHQAALKQFGKSCELIPCQSFKDVFDMVDRGKAQYGVVPVENSSEGSVTAVMDLF
CCCCCHHHHHHHHHCCCCCEECCHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHH
VTSPLKICAQINLNIRNSLMADIPREHIRILYSHPQVLGQTRNWIQRHFPNAELVETSST
HHCHHHHHHHCCCCHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEECCCC
TKASILAKENAAMGAASLGCPLAAELFGLNILEEDVQDQSCNTTRFAVIGRQETQPSGRD
CHHHEEECCCCCCCHHHCCCCHHHHHHCCHHHHHHHCCCCCCCEEEEEEECCCCCCCCCC
RTSLLIRIQHKPGTLAEVVNCFQRHNNNLIRIESRPSKVINWEYVFYIDAAGHIQESPLR
CEEEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEEEEECCCCCCCCHHH
ETLPELEQHCSMLKILGSYADTDVI
HHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
METTHHGEDASPDNPPRQQKSGNTDEQTIALTKARLAIDEVDARIVELLKKRAEWVHEVG
CCCCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIKKEKNSPIFVPERETALLNKLNRLNAGVLPEASLQAIYREIISCSFFLEGGLTIAYLG
HHHHHCCCCEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEECCCEEEEEC
PKGTWSHQAALKQFGKSCELIPCQSFKDVFDMVDRGKAQYGVVPVENSSEGSVTAVMDLF
CCCCCHHHHHHHHHCCCCCEECCHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHH
VTSPLKICAQINLNIRNSLMADIPREHIRILYSHPQVLGQTRNWIQRHFPNAELVETSST
HHCHHHHHHHCCCCHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEECCCC
TKASILAKENAAMGAASLGCPLAAELFGLNILEEDVQDQSCNTTRFAVIGRQETQPSGRD
CHHHEEECCCCCCCHHHCCCCHHHHHHCCHHHHHHHCCCCCCCEEEEEEECCCCCCCCCC
RTSLLIRIQHKPGTLAEVVNCFQRHNNNLIRIESRPSKVINWEYVFYIDAAGHIQESPLR
CEEEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEEEEECCCCCCCCHHH
ETLPELEQHCSMLKILGSYADTDVI
HHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]