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The map label for this gene is paaE [H]

Identifier: 186477609

GI number: 186477609

Start: 3212328

End: 3213416

Strand: Direct

Name: paaE [H]

Synonym: Bphy_2861

Alternate gene names: 186477609

Gene position: 3212328-3213416 (Clockwise)

Preceding gene: 186477608

Following gene: 186477610

Centisome position: 92.33

GC content: 61.98

Gene sequence:

>1089_bases
ATGGCCACCCCGCAATTTCATCCGCTGCGCATCCGGGAAGTGCGGCCGGAAACCGCCGATGCGGTCTCCGTCGCCTTCGA
AGTCCCCGTCGAACTGCGCGAGCAGTTTCGCTTCACGCAAGGCCAGTTCGTCACGCTGAAGACGCACATCGACGGTGAGG
AAACGCGCCGCTCGTATTCGATCTGCGTTGGCGTCACCGATTACGACCGTGACGGCGAACTCCGCATCGGCATCAAGCGC
GTGCGCGGCGGCCGCTTCTCGAACTTCGCGTTCGATACGCTGCAACCCGGCCACACCATCGATGTAATGACGCCCGACGG
TCGTTTCTTCACGCACCTGAACGCCGACAACGGCAAGCAGTACGTCGCATTCGCGGGCGGCTCGGGCATCACGCCCGTGC
TGGCAATCGTGAAGACGACGCTCGAAATCGAGCCCCGCAGCACATTCACACTGATTTACGGCAATCGCAGCGTCGATCAG
ATCATGTTCGCCGAGGAACTCGAAGACCTGAAGAACCGGTTCATGAACCGTTTCGTGCTGTATCACGTGCTGTCCGACGA
TCTCCAGGACGTCGAACTGTTCAATGGCGTGCTCGATCAGGCGAAGTGCGCGTCGTTCCTTGAGACGCTGATCCCTGCCG
AGGCGATCGACGAAGCGTTCATTTGCGGCCCGGCGCCGATGATGGATGCCGCCGAAGCCGCATTGAAGGCCGCGGGCGTC
CCGCAGGAGAAAGTGCACGTCGAGCGTTTCGGCACACCGCTGCCGCAAGCGGGCGTGCCCGCCGCGGAAATCACCGACGA
CACGCCGACCGCCGACCTCGAAATCGTGCTTGACGGCAAGAAGCGCAAGCTGCGCTTGCCGTACCAGGGCTTGAGCGTGC
TCGACGTCGGTCTGCGTGCGGGCCTCGCGCTGCCGTATGCGTGCAAGGGCGGCGTCTGCTGCACGTGCCGCGCAAAGGTG
CTGGAAGGCGAAGTGACGATGGAAAAGAACTACACGCTGGAAGAACATGAGATCAAGGATGGCTTCGTGCTGACCTGCCA
GTGTCATCCGATCAGCGACAAGGTCGTCGTCAGCTACGACGAACGTTGA

Upstream 100 bases:

>100_bases
CACACCGAACGCCTCGCGCAATTCGGCTCGACGGCATGCAAAGCGCTGTATCGCTGTATCGACTGCCGTGAACCCTTCGA
CTACTTCAAACCGTACTGAT

Downstream 100 bases:

>100_bases
CACCCGCGCGGCGCACACGCGATGCGCCGCACGCCATGCACGGTATCTGCGCGTCGTCGCTTTCGACATACACGCGATCC
GCTTACACTAGGGGCCGCTC

Product: phenylacetate-CoA oxygenase/reductase subunit PaaK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MATPQFHPLRIREVRPETADAVSVAFEVPVELREQFRFTQGQFVTLKTHIDGEETRRSYSICVGVTDYDRDGELRIGIKR
VRGGRFSNFAFDTLQPGHTIDVMTPDGRFFTHLNADNGKQYVAFAGGSGITPVLAIVKTTLEIEPRSTFTLIYGNRSVDQ
IMFAEELEDLKNRFMNRFVLYHVLSDDLQDVELFNGVLDQAKCASFLETLIPAEAIDEAFICGPAPMMDAAEAALKAAGV
PQEKVHVERFGTPLPQAGVPAAEITDDTPTADLEIVLDGKKRKLRLPYQGLSVLDVGLRAGLALPYACKGGVCCTCRAKV
LEGEVTMEKNYTLEEHEIKDGFVLTCQCHPISDKVVVSYDER

Sequences:

>Translated_362_residues
MATPQFHPLRIREVRPETADAVSVAFEVPVELREQFRFTQGQFVTLKTHIDGEETRRSYSICVGVTDYDRDGELRIGIKR
VRGGRFSNFAFDTLQPGHTIDVMTPDGRFFTHLNADNGKQYVAFAGGSGITPVLAIVKTTLEIEPRSTFTLIYGNRSVDQ
IMFAEELEDLKNRFMNRFVLYHVLSDDLQDVELFNGVLDQAKCASFLETLIPAEAIDEAFICGPAPMMDAAEAALKAAGV
PQEKVHVERFGTPLPQAGVPAAEITDDTPTADLEIVLDGKKRKLRLPYQGLSVLDVGLRAGLALPYACKGGVCCTCRAKV
LEGEVTMEKNYTLEEHEIKDGFVLTCQCHPISDKVVVSYDER
>Mature_361_residues
ATPQFHPLRIREVRPETADAVSVAFEVPVELREQFRFTQGQFVTLKTHIDGEETRRSYSICVGVTDYDRDGELRIGIKRV
RGGRFSNFAFDTLQPGHTIDVMTPDGRFFTHLNADNGKQYVAFAGGSGITPVLAIVKTTLEIEPRSTFTLIYGNRSVDQI
MFAEELEDLKNRFMNRFVLYHVLSDDLQDVELFNGVLDQAKCASFLETLIPAEAIDEAFICGPAPMMDAAEAALKAAGVP
QEKVHVERFGTPLPQAGVPAAEITDDTPTADLEIVLDGKKRKLRLPYQGLSVLDVGLRAGLALPYACKGGVCCTCRAKVL
EGEVTMEKNYTLEEHEIKDGFVLTCQCHPISDKVVVSYDER

Specific function: May be part of a multicomponent oxygenase involved in phenylacetyl-CoA hydroxylation [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI49574502, Length=216, Percent_Identity=28.2407407407407, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1787658, Length=357, Percent_Identity=45.0980392156863, Blast_Score=315, Evalue=3e-87,
Organism=Escherichia coli, GI1787098, Length=356, Percent_Identity=24.438202247191, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR011884
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 40138; Mature: 40007

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPQFHPLRIREVRPETADAVSVAFEVPVELREQFRFTQGQFVTLKTHIDGEETRRSYS
CCCCCCCCEEEEECCCCCCCEEEEEEECCHHHHHHHCCCCCEEEEEEEECCCHHHCCEEE
ICVGVTDYDRDGELRIGIKRVRGGRFSNFAFDTLQPGHTIDVMTPDGRFFTHLNADNGKQ
EEEEEECCCCCCCEEEEEEEECCCCCCCEEECCCCCCCEEEEECCCCCEEEEEECCCCCE
YVAFAGGSGITPVLAIVKTTLEIEPRSTFTLIYGNRSVDQIMFAEELEDLKNRFMNRFVL
EEEEECCCCCHHHHHHHHHHEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
YHVLSDDLQDVELFNGVLDQAKCASFLETLIPAEAIDEAFICGPAPMMDAAEAALKAAGV
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEECCCCHHHHHHHHHHHCCC
PQEKVHVERFGTPLPQAGVPAAEITDDTPTADLEIVLDGKKRKLRLPYQGLSVLDVGLRA
CHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCEEEEEECCCCCEEECCCCCCHHHHHHHHC
GLALPYACKGGVCCTCRAKVLEGEVTMEKNYTLEEHEIKDGFVLTCQCHPISDKVVVSYD
CCCCCCCCCCCEEEEEEEEEECCEEEEECCCCCCCCCCCCCEEEEEEECCCCCCEEEEEC
ER
CC
>Mature Secondary Structure 
ATPQFHPLRIREVRPETADAVSVAFEVPVELREQFRFTQGQFVTLKTHIDGEETRRSYS
CCCCCCCEEEEECCCCCCCEEEEEEECCHHHHHHHCCCCCEEEEEEEECCCHHHCCEEE
ICVGVTDYDRDGELRIGIKRVRGGRFSNFAFDTLQPGHTIDVMTPDGRFFTHLNADNGKQ
EEEEEECCCCCCCEEEEEEEECCCCCCCEEECCCCCCCEEEEECCCCCEEEEEECCCCCE
YVAFAGGSGITPVLAIVKTTLEIEPRSTFTLIYGNRSVDQIMFAEELEDLKNRFMNRFVL
EEEEECCCCCHHHHHHHHHHEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
YHVLSDDLQDVELFNGVLDQAKCASFLETLIPAEAIDEAFICGPAPMMDAAEAALKAAGV
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEECCCCHHHHHHHHHHHCCC
PQEKVHVERFGTPLPQAGVPAAEITDDTPTADLEIVLDGKKRKLRLPYQGLSVLDVGLRA
CHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCEEEEEECCCCCEEECCCCCCHHHHHHHHC
GLALPYACKGGVCCTCRAKVLEGEVTMEKNYTLEEHEIKDGFVLTCQCHPISDKVVVSYD
CCCCCCCCCCCEEEEEEEEEECCEEEEECCCCCCCCCCCCCEEEEEEECCCCCCEEEEEC
ER
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD [C]

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]