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The map label for this gene is secY [H]

Identifier: 186477567

GI number: 186477567

Start: 3170388

End: 3171734

Strand: Reverse

Name: secY [H]

Synonym: Bphy_2819

Alternate gene names: 186477567

Gene position: 3171734-3170388 (Counterclockwise)

Preceding gene: 186477568

Following gene: 186477566

Centisome position: 91.16

GC content: 57.46

Gene sequence:

>1347_bases
TTGGCTAACAGCCCGAGTCTCGCAAAACCCGGTCGAAGCGCGGCGAAGTTTGGCGATCTGCGTCGGCGAGCAGTGTTCCT
GCTGCTGGCGCTGGTCGTCTACCGGATTGGCGCGCATATTCCGGTGCCGGGCATTGACCCGGACCAGCTGGCAAAGCTGT
TCCAAAGCCAGTCGGGCGGCATCCTTGGCATGTTCAACATGTTCTCGGGTGGCGCACTTTCGCGGTTCACGATTTTCGCG
CTGGGGATCATGCCCTACATCTCGGCGTCGATCATCATGCAGTTGCTGGCGATCGTCTCGCCGCAGCTGGAAGCGCTGAA
GAAGGAAGGGCAGGCAGGTCAGCGGAAGATCACGCAGTACACACGGGTCTTTACGGTGGTTCTGGCTACGTTCCAGGCCT
TTGGTATCGCTGTCGCGCTGGAAAACCAGCCGGCACTCGTTATCGATCCTGGCATGGTCTTCCGGCTGACGACGGTTGTG
ACGCTCGTGACCGGCACGATGTTCCTGATGTGGCTCGGTGAGCAAATCACGGAACGCGGTCTCGGTAACGGCATTTCGAT
CATTATTTTCGGCGGTATCGCGGCGGGCTTCCCGAATGCGATCGGTGGTCTCTTTGAACTGGTTCGTACCGGTTCGATGA
GCATCATTTCGGCGATCATCGTGGTCGCGCTGATTGCTGCAGTGACGTATCTGGTGGTGTTCATCGAACGCGGCCAGCGC
AAGATTCTTGTGAACTACGCCAAGCGGCAGGTCGGCAACAAGATTTACGGTGGACAGTCGTCGCATCTGCCGCTGAAGTT
GAACATGTCGGGCGTGATTCCGCCGATCTTCGCATCGTCGATCATCCTGTTCCCGGCAACCATCCTGAACTGGTTTAGTT
CTGGGTCGCGGACTGGCTGGTTCGCAGACACGCTGCACAATGTGGCCGAAGCGCTCAAGCCAGGTCAGCCGGTGTACGTG
TTGCTGTATGCGTTGGCGATCGTGTTCTTCTGCTTCTTCTACACCGCGCTGGTGTTCAACAGCAGGGAGACGGCCGACAA
CCTGAAGAAGAGTGGTGCATTCGTCCCTGGTATTCGTCCGGGTGACCAGACGGCACGCTATATCGACCGCATCCTGACGC
GTCTGACGTTGGCCGGTGCGATCTACATCGTGTTTGTTTGCTTGCTGCCCGAGTTCTTGGTGCTGCGTTGGAATGTGCCG
TTTTATTTTGGTGGAACGTCGCTGCTGATCATTGTCGTCGTCACAATGGATTTCATGGCGCAGGTGCAGTCGTACGTTAT
GTCGCAACAGTATGAGTCGCTGCTGAAGAAGGCAAACTTCAAAGGCGGCGGCGTCCCGATGCGTTGA

Upstream 100 bases:

>100_bases
ACGAAGGGCGCGCGCGCTGCGATCGAAGCAGCGGGCGGTTCTTTCGCCGAGTAACGTGCAAGTCGATTGCCGTCACTAGC
ATTTGCATCGGAGAAGGTAC

Downstream 100 bases:

>100_bases
AAGGACTTATGGCCAAAGACGATGTAATCCAGATGCAGGGTGAGGTTATCGAAAACCTCCCCAACGCTACCTTCCGGGTG
AAGCTGGAAAACGGCCATGT

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MANSPSLAKPGRSAAKFGDLRRRAVFLLLALVVYRIGAHIPVPGIDPDQLAKLFQSQSGGILGMFNMFSGGALSRFTIFA
LGIMPYISASIIMQLLAIVSPQLEALKKEGQAGQRKITQYTRVFTVVLATFQAFGIAVALENQPALVIDPGMVFRLTTVV
TLVTGTMFLMWLGEQITERGLGNGISIIIFGGIAAGFPNAIGGLFELVRTGSMSIISAIIVVALIAAVTYLVVFIERGQR
KILVNYAKRQVGNKIYGGQSSHLPLKLNMSGVIPPIFASSIILFPATILNWFSSGSRTGWFADTLHNVAEALKPGQPVYV
LLYALAIVFFCFFYTALVFNSRETADNLKKSGAFVPGIRPGDQTARYIDRILTRLTLAGAIYIVFVCLLPEFLVLRWNVP
FYFGGTSLLIIVVVTMDFMAQVQSYVMSQQYESLLKKANFKGGGVPMR

Sequences:

>Translated_448_residues
MANSPSLAKPGRSAAKFGDLRRRAVFLLLALVVYRIGAHIPVPGIDPDQLAKLFQSQSGGILGMFNMFSGGALSRFTIFA
LGIMPYISASIIMQLLAIVSPQLEALKKEGQAGQRKITQYTRVFTVVLATFQAFGIAVALENQPALVIDPGMVFRLTTVV
TLVTGTMFLMWLGEQITERGLGNGISIIIFGGIAAGFPNAIGGLFELVRTGSMSIISAIIVVALIAAVTYLVVFIERGQR
KILVNYAKRQVGNKIYGGQSSHLPLKLNMSGVIPPIFASSIILFPATILNWFSSGSRTGWFADTLHNVAEALKPGQPVYV
LLYALAIVFFCFFYTALVFNSRETADNLKKSGAFVPGIRPGDQTARYIDRILTRLTLAGAIYIVFVCLLPEFLVLRWNVP
FYFGGTSLLIIVVVTMDFMAQVQSYVMSQQYESLLKKANFKGGGVPMR
>Mature_447_residues
ANSPSLAKPGRSAAKFGDLRRRAVFLLLALVVYRIGAHIPVPGIDPDQLAKLFQSQSGGILGMFNMFSGGALSRFTIFAL
GIMPYISASIIMQLLAIVSPQLEALKKEGQAGQRKITQYTRVFTVVLATFQAFGIAVALENQPALVIDPGMVFRLTTVVT
LVTGTMFLMWLGEQITERGLGNGISIIIFGGIAAGFPNAIGGLFELVRTGSMSIISAIIVVALIAAVTYLVVFIERGQRK
ILVNYAKRQVGNKIYGGQSSHLPLKLNMSGVIPPIFASSIILFPATILNWFSSGSRTGWFADTLHNVAEALKPGQPVYVL
LYALAIVFFCFFYTALVFNSRETADNLKKSGAFVPGIRPGDQTARYIDRILTRLTLAGAIYIVFVCLLPEFLVLRWNVPF
YFGGTSLLIIVVVTMDFMAQVQSYVMSQQYESLLKKANFKGGGVPMR

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=451, Percent_Identity=65.1884700665188, Blast_Score=533, Evalue=1e-153,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 48777; Mature: 48645

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANSPSLAKPGRSAAKFGDLRRRAVFLLLALVVYRIGAHIPVPGIDPDQLAKLFQSQSGG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCC
ILGMFNMFSGGALSRFTIFALGIMPYISASIIMQLLAIVSPQLEALKKEGQAGQRKITQY
EEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHH
TRVFTVVLATFQAFGIAVALENQPALVIDPGMVFRLTTVVTLVTGTMFLMWLGEQITERG
HHHHHHHHHHHHHHHEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LGNGISIIIFGGIAAGFPNAIGGLFELVRTGSMSIISAIIVVALIAAVTYLVVFIERGQR
CCCCCEEEEECCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
KILVNYAKRQVGNKIYGGQSSHLPLKLNMSGVIPPIFASSIILFPATILNWFSSGSRTGW
HHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCH
FADTLHNVAEALKPGQPVYVLLYALAIVFFCFFYTALVFNSRETADNLKKSGAFVPGIRP
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
GDQTARYIDRILTRLTLAGAIYIVFVCLLPEFLVLRWNVPFYFGGTSLLIIVVVTMDFMA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHH
QVQSYVMSQQYESLLKKANFKGGGVPMR
HHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
ANSPSLAKPGRSAAKFGDLRRRAVFLLLALVVYRIGAHIPVPGIDPDQLAKLFQSQSGG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCC
ILGMFNMFSGGALSRFTIFALGIMPYISASIIMQLLAIVSPQLEALKKEGQAGQRKITQY
EEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHH
TRVFTVVLATFQAFGIAVALENQPALVIDPGMVFRLTTVVTLVTGTMFLMWLGEQITERG
HHHHHHHHHHHHHHHEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LGNGISIIIFGGIAAGFPNAIGGLFELVRTGSMSIISAIIVVALIAAVTYLVVFIERGQR
CCCCCEEEEECCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
KILVNYAKRQVGNKIYGGQSSHLPLKLNMSGVIPPIFASSIILFPATILNWFSSGSRTGW
HHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCH
FADTLHNVAEALKPGQPVYVLLYALAIVFFCFFYTALVFNSRETADNLKKSGAFVPGIRP
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
GDQTARYIDRILTRLTLAGAIYIVFVCLLPEFLVLRWNVPFYFGGTSLLIIVVVTMDFMA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHH
QVQSYVMSQQYESLLKKANFKGGGVPMR
HHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9322765; 10952301 [H]