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The map label for this gene is dsbD [H]

Identifier: 186477558

GI number: 186477558

Start: 3164436

End: 3166292

Strand: Reverse

Name: dsbD [H]

Synonym: Bphy_2810

Alternate gene names: 186477558

Gene position: 3166292-3164436 (Counterclockwise)

Preceding gene: 186477559

Following gene: 186477555

Centisome position: 91.01

GC content: 63.0

Gene sequence:

>1857_bases
ATGTATAACCGTTTGTCCCGTCGCTGGCGCGATGTCGCGCGCGTTTTCGCCGTGATTGCCGGCTTCTTGTTGCTGTCGTT
CAGTTCGGTCGGCGTTGTCCGCGCAGACGACTTCCTCGATCTCTCGGAGGCGTTCAGATTCAGCGCGTCCGAGCAACCGG
GCGAGGTGCTGGTTCATTACAAGATTGCCGACGGTTACTACATGTACCGCGAGCGGTTCGCGTTCGCGACACGCAACGGC
GCGGGCAAGCTCGGTGATGCGCAATTGCCCGCAGGTCACGTGAAGTTCGATCAGACCTTCAACAAAAACGTCGAGACGTA
TCGCGGTGAGCTGACCATTCGCGTGCCCGTGAGTCAGGCGAGCGGTGCGTTCGACCTCGCCGTGACGTCGCAAGGTTGTG
CGGATGCAGGAATCTGCTATCCGCCGATGGAGCGCGTCTATCACGTGTCGGGCGCCGCACTACATGCCGCCGCAGCAGGC
ACCGTGCAGCTGTCGCCGCCTCACGAGGACAGCTCGGGCAACGCATCTTGGTACGAGCGCGCAACCAGCGCTGACTACGC
GCAATCGCTGCTCCAGGGCGGCGGCTTCTTTGCAATCGTCGGATTGTATTTCGTCGCCGGCATCGTGCTGAGCCTGCTGC
CGTGCTCGTATCCGATGATCCCGATCCTGTCCGCGATCATCATTGGCGAAGGCCCGCGCGTGACGCGGGCGCGCGGTTTT
GCGCTGTCACTGGCCTATGTCGTCGGGATGGCGCTCGTCTACACGGTGCTTGGCGTCGCGGCGGCACTCGTCGGGCAGAG
CATGGGCGCCCGGCTGCAGAATCCGTGGGTGCTCGGCGCATTTGCAGTTCTTCTGACCGTATTTGCGCTAACGCTGATCG
CTGGCGTGGATATCGTACTGCCTCACGGGTGGCAGCGCGGCGTTTCGAAGGCCTCCGAGGGGCGCTCGGGCGGGAAATTC
GCCGCGGTCGCGGTGATGGGGGCGCTTTCGGCGCTGGTGGTCGGTGCATGCATGACGGCGCCCCTATTTGCGGTACTCGC
CTTCATCGCGCACACGGGCAACGCCGTCCTAGGCGGTGTAGCCCTATTTTCGATGGGCATCGGGCTTGGCGTACCGTTGC
TGCTCATTGGGCTCGGCGCGGGCACGCTGCTGCCGCGTGCCGGCGCCTGGATGGATCGCGTGAAGGTCTTCTTCGGCGTG
ATTTTGCTCGCCGCGGCATTGTGGATCGTTTGGCCGGTTTTGAGCTCGACGGCGCAAATGTTGCTGGCGGCCTCATGGCT
GCTGATCGCGGCCGCCTCTCTGGGACTGTTTTCTCCGCATGCAGGAGCAGGCTCGATCTGGCGCGGTCTTGGTCGCGGAC
TGGGTGCCGCATTGGCGATCTGGGCGGCGACGTTGCTGGCCGGTCTGGCGGCGGGATCGACGGATCCTTTGAAGCCGTTG
GCCGTGCTCGTTGGCCGTACATCCGGTACAGCTTCCGAGCAGGCGCAGCAGAGCGATCTGGCGTTCGCCCGTGTACGCAG
CTCGGGCCAGTTCGACGAGGCCGTCAAAACGGCCGCTAAGCCCGCTATGCTCGATTTTTACGCAGACTGGTGCGTCAGCT
GCAAAGAAATGGAGAAGTTTACCTTTAGCGACCCGCGCGTCCAGGCGAAGCTCAAGCAGTTCAACCTTCTGCGCGCCGAC
GTGACGGCCAATAACGCGGACGATCAGGCACTGCTCAAACGGTTCAACCTGTTTGGGCCACCCGGAATCATCTTCTTCGA
CCGAGGTGGCAAAGAAGTGCTGCGCGTCGTCGGGTATGAGTCGGCGGACAAATTCCTGAACAGTCTGGCTCGGATGATGC
CGGGCCCTCAGACCTGA

Upstream 100 bases:

>100_bases
GCTCAGCATCCGTACGACACTCCCGAGATCCTTTCATGGCAAGTCACCGCATCGGCCGCTTACGGCCAATGGGTGAACGC
CGAAACCCAACGCCCGATCC

Downstream 100 bases:

>100_bases
AGCGTCGGGCGGAAGGTCGGCGCGAGGTGCCGGCGCAGCGCCCGCATGATCCGGATTAAAAGAGAGAAGCGGAGGCTGTC
AGGTCGACCCCTCCGCTTGC

Product: protein-disulfide reductase

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MYNRLSRRWRDVARVFAVIAGFLLLSFSSVGVVRADDFLDLSEAFRFSASEQPGEVLVHYKIADGYYMYRERFAFATRNG
AGKLGDAQLPAGHVKFDQTFNKNVETYRGELTIRVPVSQASGAFDLAVTSQGCADAGICYPPMERVYHVSGAALHAAAAG
TVQLSPPHEDSSGNASWYERATSADYAQSLLQGGGFFAIVGLYFVAGIVLSLLPCSYPMIPILSAIIIGEGPRVTRARGF
ALSLAYVVGMALVYTVLGVAAALVGQSMGARLQNPWVLGAFAVLLTVFALTLIAGVDIVLPHGWQRGVSKASEGRSGGKF
AAVAVMGALSALVVGACMTAPLFAVLAFIAHTGNAVLGGVALFSMGIGLGVPLLLIGLGAGTLLPRAGAWMDRVKVFFGV
ILLAAALWIVWPVLSSTAQMLLAASWLLIAAASLGLFSPHAGAGSIWRGLGRGLGAALAIWAATLLAGLAAGSTDPLKPL
AVLVGRTSGTASEQAQQSDLAFARVRSSGQFDEAVKTAAKPAMLDFYADWCVSCKEMEKFTFSDPRVQAKLKQFNLLRAD
VTANNADDQALLKRFNLFGPPGIIFFDRGGKEVLRVVGYESADKFLNSLARMMPGPQT

Sequences:

>Translated_618_residues
MYNRLSRRWRDVARVFAVIAGFLLLSFSSVGVVRADDFLDLSEAFRFSASEQPGEVLVHYKIADGYYMYRERFAFATRNG
AGKLGDAQLPAGHVKFDQTFNKNVETYRGELTIRVPVSQASGAFDLAVTSQGCADAGICYPPMERVYHVSGAALHAAAAG
TVQLSPPHEDSSGNASWYERATSADYAQSLLQGGGFFAIVGLYFVAGIVLSLLPCSYPMIPILSAIIIGEGPRVTRARGF
ALSLAYVVGMALVYTVLGVAAALVGQSMGARLQNPWVLGAFAVLLTVFALTLIAGVDIVLPHGWQRGVSKASEGRSGGKF
AAVAVMGALSALVVGACMTAPLFAVLAFIAHTGNAVLGGVALFSMGIGLGVPLLLIGLGAGTLLPRAGAWMDRVKVFFGV
ILLAAALWIVWPVLSSTAQMLLAASWLLIAAASLGLFSPHAGAGSIWRGLGRGLGAALAIWAATLLAGLAAGSTDPLKPL
AVLVGRTSGTASEQAQQSDLAFARVRSSGQFDEAVKTAAKPAMLDFYADWCVSCKEMEKFTFSDPRVQAKLKQFNLLRAD
VTANNADDQALLKRFNLFGPPGIIFFDRGGKEVLRVVGYESADKFLNSLARMMPGPQT
>Mature_618_residues
MYNRLSRRWRDVARVFAVIAGFLLLSFSSVGVVRADDFLDLSEAFRFSASEQPGEVLVHYKIADGYYMYRERFAFATRNG
AGKLGDAQLPAGHVKFDQTFNKNVETYRGELTIRVPVSQASGAFDLAVTSQGCADAGICYPPMERVYHVSGAALHAAAAG
TVQLSPPHEDSSGNASWYERATSADYAQSLLQGGGFFAIVGLYFVAGIVLSLLPCSYPMIPILSAIIIGEGPRVTRARGF
ALSLAYVVGMALVYTVLGVAAALVGQSMGARLQNPWVLGAFAVLLTVFALTLIAGVDIVLPHGWQRGVSKASEGRSGGKF
AAVAVMGALSALVVGACMTAPLFAVLAFIAHTGNAVLGGVALFSMGIGLGVPLLLIGLGAGTLLPRAGAWMDRVKVFFGV
ILLAAALWIVWPVLSSTAQMLLAASWLLIAAASLGLFSPHAGAGSIWRGLGRGLGAALAIWAATLLAGLAAGSTDPLKPL
AVLVGRTSGTASEQAQQSDLAFARVRSSGQFDEAVKTAAKPAMLDFYADWCVSCKEMEKFTFSDPRVQAKLKQFNLLRAD
VTANNADDQALLKRFNLFGPPGIIFFDRGGKEVLRVVGYESADKFLNSLARMMPGPQT

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=610, Percent_Identity=35.7377049180328, Blast_Score=327, Evalue=2e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 65261; Mature: 65261

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNRLSRRWRDVARVFAVIAGFLLLSFSSVGVVRADDFLDLSEAFRFSASEQPGEVLVHY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHCCCCCCCCCEEEEE
KIADGYYMYRERFAFATRNGAGKLGDAQLPAGHVKFDQTFNKNVETYRGELTIRVPVSQA
EECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECHHHCCCCHHCCCEEEEEEECCCC
SGAFDLAVTSQGCADAGICYPPMERVYHVSGAALHAAAAGTVQLSPPHEDSSGNASWYER
CCCEEEEEECCCCCCCCCCCCCHHHHHHHCCHHHHHHCCCEEEECCCCCCCCCCCHHHHH
ATSADYAQSLLQGGGFFAIVGLYFVAGIVLSLLPCSYPMIPILSAIIIGEGPRVTRARGF
HCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHH
ALSLAYVVGMALVYTVLGVAAALVGQSMGARLQNPWVLGAFAVLLTVFALTLIAGVDIVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHEE
PHGWQRGVSKASEGRSGGKFAAVAVMGALSALVVGACMTAPLFAVLAFIAHTGNAVLGGV
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ALFSMGIGLGVPLLLIGLGAGTLLPRAGAWMDRVKVFFGVILLAAALWIVWPVLSSTAQM
HHHHHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAASWLLIAAASLGLFSPHAGAGSIWRGLGRGLGAALAIWAATLLAGLAAGSTDPLKPL
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
AVLVGRTSGTASEQAQQSDLAFARVRSSGQFDEAVKTAAKPAMLDFYADWCVSCKEMEKF
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
TFSDPRVQAKLKQFNLLRADVTANNADDQALLKRFNLFGPPGIIFFDRGGKEVLRVVGYE
CCCCHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCCC
SADKFLNSLARMMPGPQT
HHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MYNRLSRRWRDVARVFAVIAGFLLLSFSSVGVVRADDFLDLSEAFRFSASEQPGEVLVHY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHCCCCCCCCCEEEEE
KIADGYYMYRERFAFATRNGAGKLGDAQLPAGHVKFDQTFNKNVETYRGELTIRVPVSQA
EECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECHHHCCCCHHCCCEEEEEEECCCC
SGAFDLAVTSQGCADAGICYPPMERVYHVSGAALHAAAAGTVQLSPPHEDSSGNASWYER
CCCEEEEEECCCCCCCCCCCCCHHHHHHHCCHHHHHHCCCEEEECCCCCCCCCCCHHHHH
ATSADYAQSLLQGGGFFAIVGLYFVAGIVLSLLPCSYPMIPILSAIIIGEGPRVTRARGF
HCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHH
ALSLAYVVGMALVYTVLGVAAALVGQSMGARLQNPWVLGAFAVLLTVFALTLIAGVDIVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHEE
PHGWQRGVSKASEGRSGGKFAAVAVMGALSALVVGACMTAPLFAVLAFIAHTGNAVLGGV
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ALFSMGIGLGVPLLLIGLGAGTLLPRAGAWMDRVKVFFGVILLAAALWIVWPVLSSTAQM
HHHHHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAASWLLIAAASLGLFSPHAGAGSIWRGLGRGLGAALAIWAATLLAGLAAGSTDPLKPL
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
AVLVGRTSGTASEQAQQSDLAFARVRSSGQFDEAVKTAAKPAMLDFYADWCVSCKEMEKF
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
TFSDPRVQAKLKQFNLLRADVTANNADDQALLKRFNLFGPPGIIFFDRGGKEVLRVVGYE
CCCCHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCCC
SADKFLNSLARMMPGPQT
HHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]