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The map label for this gene is trpD [H]

Identifier: 186477448

GI number: 186477448

Start: 3053498

End: 3054526

Strand: Direct

Name: trpD [H]

Synonym: Bphy_2700

Alternate gene names: 186477448

Gene position: 3053498-3054526 (Clockwise)

Preceding gene: 186477447

Following gene: 186477449

Centisome position: 87.76

GC content: 62.78

Gene sequence:

>1029_bases
ATGATTACGCCACAGGAAGCGCTGCAACGCACGATCGAGCATCGCGAGATTTTCCACGACGAGATGCTGCACCTGATGCG
TCTCATCATGCGCGGCGACATGTCGCCCGTGATGGCGGCTGCAATCATCACCGGCCTGCGCGTCAAAAAAGAGACCATCG
GCGAAATCACCGCGGCCGCCACGGTGATGCGTGAGTTCGCGCGTCATGTCGACGTGCAGGACAACTCGAACTTCGTCGAT
ATCGTCGGTACGGGCGGCGACGGATCGCATACGTTCAACATTTCGACGGCCACGATGTTCGTGTCGGCCGCGGCGGGCGC
GAAGGTCGCGAAGCACGGCAATCGCGGCGTATCGAGCAAGTCGGGCAGCGCGGACGTGCTAGAAGCGCTCGGCGTGAACA
TCGACCTGCAGCCGGAACAGGTGGCGGCTTCCATCACCGAAACGGGCATGGGCTTCATGTTCGCGCCGAACCATCATCCC
GCGATGAAGAACATCGCGCCCGTGCGGCGCGAACTCGGCGTGCGGACCATCTTCAACATTCTCGGTCCGCTGACGAATCC
GGCCGGCGCGCCGAACCAGCTACAAGGCGTGTTTCACCCGGATCTCGTCGGCATTCAGGTTCGAGTGATGCAACGTCTCG
GCGCACGCCACGTGCTGGTCGTGTACGGTAGGGACGGCATGGACGAAGTGTCGCTGGGAGCGGCGACGCTCGTCGGCGAA
CTGCGTAACGGCGAAATAACCGAATACGAGATTCATCCCGAGGACTTCGGTATGCAGATGGTGTCGAACCGCACGCTGAA
GGTGGCGGACGCGGCGGAATCGAAAGTTCTGCTGCTCGAGGCGCTCGACAACAAGCCTGGCGTCGCGCGCGAGATCGTCA
CGCTGAACGCGGGCACGGCACTCTACTCGGCCAACGTCGCGGAGTCGATCGCGGACGGCATCCGGCTGGCGCGTGAGGCG
ATCGCGAGCGGCAAGGCACGCGCGAAAGTCGACGAACTGGTCCGCTTCACGCAGCAGTTCAAGCATTGA

Upstream 100 bases:

>100_bases
AATCGATTCTGTCGGAACATGGCCACGCGTTGCTCGAAAACTTCGTGAAGCAGTCGAAAACCGCGGCACGCAGCGCCTGA
ATATAAGAGGAGACGTCACC

Downstream 100 bases:

>100_bases
TCAAGTAACGGAAATCACATGAGCGATATTCTCGACCGCATCATCGACGTCAAGCGCCAAGAAGTGCGCGCCGCGCAGCA
AAGCGCGCCGCTCGAAGAAC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MITPQEALQRTIEHREIFHDEMLHLMRLIMRGDMSPVMAAAIITGLRVKKETIGEITAAATVMREFARHVDVQDNSNFVD
IVGTGGDGSHTFNISTATMFVSAAAGAKVAKHGNRGVSSKSGSADVLEALGVNIDLQPEQVAASITETGMGFMFAPNHHP
AMKNIAPVRRELGVRTIFNILGPLTNPAGAPNQLQGVFHPDLVGIQVRVMQRLGARHVLVVYGRDGMDEVSLGAATLVGE
LRNGEITEYEIHPEDFGMQMVSNRTLKVADAAESKVLLLEALDNKPGVAREIVTLNAGTALYSANVAESIADGIRLAREA
IASGKARAKVDELVRFTQQFKH

Sequences:

>Translated_342_residues
MITPQEALQRTIEHREIFHDEMLHLMRLIMRGDMSPVMAAAIITGLRVKKETIGEITAAATVMREFARHVDVQDNSNFVD
IVGTGGDGSHTFNISTATMFVSAAAGAKVAKHGNRGVSSKSGSADVLEALGVNIDLQPEQVAASITETGMGFMFAPNHHP
AMKNIAPVRRELGVRTIFNILGPLTNPAGAPNQLQGVFHPDLVGIQVRVMQRLGARHVLVVYGRDGMDEVSLGAATLVGE
LRNGEITEYEIHPEDFGMQMVSNRTLKVADAAESKVLLLEALDNKPGVAREIVTLNAGTALYSANVAESIADGIRLAREA
IASGKARAKVDELVRFTQQFKH
>Mature_342_residues
MITPQEALQRTIEHREIFHDEMLHLMRLIMRGDMSPVMAAAIITGLRVKKETIGEITAAATVMREFARHVDVQDNSNFVD
IVGTGGDGSHTFNISTATMFVSAAAGAKVAKHGNRGVSSKSGSADVLEALGVNIDLQPEQVAASITETGMGFMFAPNHHP
AMKNIAPVRRELGVRTIFNILGPLTNPAGAPNQLQGVFHPDLVGIQVRVMQRLGARHVLVVYGRDGMDEVSLGAATLVGE
LRNGEITEYEIHPEDFGMQMVSNRTLKVADAAESKVLLLEALDNKPGVAREIVTLNAGTALYSANVAESIADGIRLAREA
IASGKARAKVDELVRFTQQFKH

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=283, Percent_Identity=42.0494699646643, Blast_Score=201, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6320561, Length=355, Percent_Identity=26.7605633802817, Blast_Score=116, Evalue=5e-27,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 36846; Mature: 36846

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITPQEALQRTIEHREIFHDEMLHLMRLIMRGDMSPVMAAAIITGLRVKKETIGEITAAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TVMREFARHVDVQDNSNFVDIVGTGGDGSHTFNISTATMFVSAAAGAKVAKHGNRGVSSK
HHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEEHHHHHHHHHCCCHHHHCCCCCCCCC
SGSADVLEALGVNIDLQPEQVAASITETGMGFMFAPNHHPAMKNIAPVRRELGVRTIFNI
CCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHH
LGPLTNPAGAPNQLQGVFHPDLVGIQVRVMQRLGARHVLVVYGRDGMDEVSLGAATLVGE
HCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHH
LRNGEITEYEIHPEDFGMQMVSNRTLKVADAAESKVLLLEALDNKPGVAREIVTLNAGTA
HCCCCEEEEEECHHHHHHHHHCCCCEEEECCCCCCEEEEEECCCCCCCHHEEEEEECCCH
LYSANVAESIADGIRLAREAIASGKARAKVDELVRFTQQFKH
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MITPQEALQRTIEHREIFHDEMLHLMRLIMRGDMSPVMAAAIITGLRVKKETIGEITAAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TVMREFARHVDVQDNSNFVDIVGTGGDGSHTFNISTATMFVSAAAGAKVAKHGNRGVSSK
HHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEEHHHHHHHHHCCCHHHHCCCCCCCCC
SGSADVLEALGVNIDLQPEQVAASITETGMGFMFAPNHHPAMKNIAPVRRELGVRTIFNI
CCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHH
LGPLTNPAGAPNQLQGVFHPDLVGIQVRVMQRLGARHVLVVYGRDGMDEVSLGAATLVGE
HCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHH
LRNGEITEYEIHPEDFGMQMVSNRTLKVADAAESKVLLLEALDNKPGVAREIVTLNAGTA
HCCCCEEEEEECHHHHHHHHHCCCCEEEECCCCCCEEEEEECCCCCCCHHEEEEEECCCH
LYSANVAESIADGIRLAREAIASGKARAKVDELVRFTQQFKH
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA