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The map label for this gene is obgE [H]

Identifier: 186477398

GI number: 186477398

Start: 2990901

End: 2992013

Strand: Reverse

Name: obgE [H]

Synonym: Bphy_2650

Alternate gene names: 186477398

Gene position: 2992013-2990901 (Counterclockwise)

Preceding gene: 186477399

Following gene: 186477397

Centisome position: 86.0

GC content: 63.61

Gene sequence:

>1113_bases
ATGAAGTTCATTGACGAAGCGAGGATCGAAGTCATCGCCGGCGACGGAGGAGATGGCAGCGCGTCGATGCGCCGCGAGAA
ATTCGTCCCGTTCGGCGGTCCGGACGGCGGCGACGGCGGCCGTGGCGGCAGCGTCTATGCAGTCGCAGATCGCAATATCA
ACACGCTGATCGATTACCGCTACTCGAAAAAGCATCAGGCTCGCAACGGCGAAAACGGTCGTGGCTCGGACTGCTATGGC
AAGGGCGGCGACGACATCACGCTGCGCATGCCTGTCGGCACCATCATCACCGACATGGACACGGGCGAGCTGATCGCCGA
CCTCACCGAGCACAATCAGACGGTGCGCATCGCCGAAGGCGGCGCGGGTGGGCTCGGCAATCTGCATTTCAAATCCAGTA
CGAATCGCGCGCCGCGACAGAAGACGGACGGCAAGCCCGGCGAACGCCGAATGGTGCGCCTCGAGTTGAAGGTGCTCGCG
GATGTCGGTTTGCTCGGCATGCCGAACGCAGGCAAGTCGACGTTCATTTCGTCGGTGTCGAACGCGAAGCCGAAGATCGC
CGACTATCCATTCACGACGCTCGCGCCCAATCTCGGCGTGGTGCGTGTCGGGCCGAGCCGCAGCTTCGTGATCGCGGATA
TTCCCGGGCTGATCGAAGGTGCGGCGGAAGGCGCGGGCCTCGGTCACCAGTTCCTGCGCCATCTGCAGCGCACGGGCCTG
TTGCTTCACATCGTCGATCTCGCACCGTTCGACGAAACCGTCGATCCCGTCGCGGAAGCCAAGGCGATCGTCAACGAACT
GCGCAAGTACGACGAAGAGCTGTTCAGCAAGCCGCGCTGGCTCGTGTTGAACAAGCTCGACATGGTGCCAGAAGACGAGC
GGGAGGCACGCGTGGCCGCGTTCCTGAAGGACTTCGAATGGGACGGCCCGGTGTTCGAAATCTCGGCGCTCACCGGTCAG
GGCTGCGAGAACCTGTGCTACGCGGTGTACGACTACCTTGCCGAGCACTCGGATGCGCAGCGCGCGGCAGAAGCCGAAGA
TCTGGCCGCCGACGTGCGTTTTCGCGGGCAGCAGCAAGGTGACGCGAACGCGCCCGTCGGGCCGCAGGAGTAA

Upstream 100 bases:

>100_bases
GCGCAAATCGACAAGAATCAGGTTCAATCTGGCCGTTCGGCCAATGGTACGTGCGCGCTGCGCGCGGCAAAATAGCAATA
CATACGGGACGGAGTAACGC

Downstream 100 bases:

>100_bases
GCGAGAGCCGTAATCTGGATGCCGGCGCACTTCCCAGCATGCGCCGGTCTTACGAATCATCTTGGAGACCGCGCACAATG
CGTTCCGTTATCGCAGATTC

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYAVADRNINTLIDYRYSKKHQARNGENGRGSDCYG
KGGDDITLRMPVGTIITDMDTGELIADLTEHNQTVRIAEGGAGGLGNLHFKSSTNRAPRQKTDGKPGERRMVRLELKVLA
DVGLLGMPNAGKSTFISSVSNAKPKIADYPFTTLAPNLGVVRVGPSRSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
LLHIVDLAPFDETVDPVAEAKAIVNELRKYDEELFSKPRWLVLNKLDMVPEDEREARVAAFLKDFEWDGPVFEISALTGQ
GCENLCYAVYDYLAEHSDAQRAAEAEDLAADVRFRGQQQGDANAPVGPQE

Sequences:

>Translated_370_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYAVADRNINTLIDYRYSKKHQARNGENGRGSDCYG
KGGDDITLRMPVGTIITDMDTGELIADLTEHNQTVRIAEGGAGGLGNLHFKSSTNRAPRQKTDGKPGERRMVRLELKVLA
DVGLLGMPNAGKSTFISSVSNAKPKIADYPFTTLAPNLGVVRVGPSRSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
LLHIVDLAPFDETVDPVAEAKAIVNELRKYDEELFSKPRWLVLNKLDMVPEDEREARVAAFLKDFEWDGPVFEISALTGQ
GCENLCYAVYDYLAEHSDAQRAAEAEDLAADVRFRGQQQGDANAPVGPQE
>Mature_370_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYAVADRNINTLIDYRYSKKHQARNGENGRGSDCYG
KGGDDITLRMPVGTIITDMDTGELIADLTEHNQTVRIAEGGAGGLGNLHFKSSTNRAPRQKTDGKPGERRMVRLELKVLA
DVGLLGMPNAGKSTFISSVSNAKPKIADYPFTTLAPNLGVVRVGPSRSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
LLHIVDLAPFDETVDPVAEAKAIVNELRKYDEELFSKPRWLVLNKLDMVPEDEREARVAAFLKDFEWDGPVFEISALTGQ
GCENLCYAVYDYLAEHSDAQRAAEAEDLAADVRFRGQQQGDANAPVGPQE

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=336, Percent_Identity=39.2857142857143, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI111955139, Length=364, Percent_Identity=34.6153846153846, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI111955063, Length=198, Percent_Identity=37.8787878787879, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI58761500, Length=150, Percent_Identity=30.6666666666667, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI4758796, Length=119, Percent_Identity=35.2941176470588, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1789574, Length=346, Percent_Identity=56.6473988439306, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI1787454, Length=100, Percent_Identity=37, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=342, Percent_Identity=38.3040935672515, Blast_Score=157, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI17552324, Length=324, Percent_Identity=32.0987654320988, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=33.8129496402878, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6321962, Length=197, Percent_Identity=38.5786802030457, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6321773, Length=158, Percent_Identity=29.746835443038, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319281, Length=89, Percent_Identity=37.0786516853933, Blast_Score=62, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24585318, Length=310, Percent_Identity=39.3548387096774, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI20129375, Length=339, Percent_Identity=36.8731563421829, Blast_Score=157, Evalue=9e-39,
Organism=Drosophila melanogaster, GI24640873, Length=150, Percent_Identity=34.6666666666667, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24640877, Length=150, Percent_Identity=34.6666666666667, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24640875, Length=150, Percent_Identity=34.6666666666667, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 39985; Mature: 39985

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYAVADRNINTLIDYR
CCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEEHHH
YSKKHQARNGENGRGSDCYGKGGDDITLRMPVGTIITDMDTGELIADLTEHNQTVRIAEG
HHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCEEEECCCCHHHHHHHHHCCCEEEEECC
GAGGLGNLHFKSSTNRAPRQKTDGKPGERRMVRLELKVLADVGLLGMPNAGKSTFISSVS
CCCCCCCEEECCCCCCCCCCCCCCCCCHHEEEEEEEHHHHCCCCCCCCCCCHHHHHHHHH
NAKPKIADYPFTTLAPNLGVVRVGPSRSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
CCCCCCCCCCHHHHCCCCCEEEECCCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHCCE
LLHIVDLAPFDETVDPVAEAKAIVNELRKYDEELFSKPRWLVLNKLDMVPEDEREARVAA
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCCHHHHHHHH
FLKDFEWDGPVFEISALTGQGCENLCYAVYDYLAEHSDAQRAAEAEDLAADVRFRGQQQG
HHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC
DANAPVGPQE
CCCCCCCCCC
>Mature Secondary Structure
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYAVADRNINTLIDYR
CCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEEHHH
YSKKHQARNGENGRGSDCYGKGGDDITLRMPVGTIITDMDTGELIADLTEHNQTVRIAEG
HHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCEEEECCCCHHHHHHHHHCCCEEEEECC
GAGGLGNLHFKSSTNRAPRQKTDGKPGERRMVRLELKVLADVGLLGMPNAGKSTFISSVS
CCCCCCCEEECCCCCCCCCCCCCCCCCHHEEEEEEEHHHHCCCCCCCCCCCHHHHHHHHH
NAKPKIADYPFTTLAPNLGVVRVGPSRSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGL
CCCCCCCCCCHHHHCCCCCEEEECCCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHCCE
LLHIVDLAPFDETVDPVAEAKAIVNELRKYDEELFSKPRWLVLNKLDMVPEDEREARVAA
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCCHHHHHHHH
FLKDFEWDGPVFEISALTGQGCENLCYAVYDYLAEHSDAQRAAEAEDLAADVRFRGQQQG
HHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC
DANAPVGPQE
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA