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The map label for this gene is dapB

Identifier: 186477339

GI number: 186477339

Start: 2929081

End: 2929878

Strand: Reverse

Name: dapB

Synonym: Bphy_2591

Alternate gene names: 186477339

Gene position: 2929878-2929081 (Counterclockwise)

Preceding gene: 186477340

Following gene: 186477338

Centisome position: 84.21

GC content: 64.41

Gene sequence:

>798_bases
ATGAAAATTGCCATCGCCGGCGCATCGGGCCGCATGGGCCGGATGCTCATCGAAACCGTTCTCAACGATCCTGAAGTCAA
GCTGTCGGGCGCGCTCGACCGCACCGGGGCTCCGCAACTCGGTCAGGACGCCGGTGCGTTTCTGGGCAAACAGACGGGCG
TGCTGATGTCGGACGACATCGACGCCGTGCTCGCGCAATCCGACTACCTGATCGACTTCACGCGCCCCGACGGCACGCTC
GCGCACATCGAAGCCGCCTTGCGCACGAACACGAAGCTCGTGATCGGCACGACGGGCTTCGACGACGCGCAGAAGGCGCG
GATCCGCGCTGCGTCGGAGAAAACCGGCATCGTGTTCGCGTCGAACTTCAGCGTCGGCGTGAACGTCACGATGAAGCTGC
TCGAATTCGCCGCGCGCCATTTCTCGCAGGGTTATGACATCGAAATCATCGAGGCGCATCATCGCCACAAGGTGGATGCG
CCTTCGGGCACCGCGCTGACGATGGGCGAAGTGATCGCCGGCGCGCTCGGCCGCAAGCTCGAAGATTGCGCCGTGTACGC
ACGCGAAGGCGTGACGGGCGAGCGCGATCCGTCCACGATCGGCTTCTCGGCGATTCGCGGCGGCGATATCGTCGGCGATC
ACACGGTGCTGTTCGCGGGCATCGGCGAGCGGATCGAAATCACGCACAAATCGGCGAGCCGTCTGTCGTACGCGCAAGGC
GCGTTGCGCGCGGTGCGCTTCCTTGAAGGCCACTCGAACGGCCTGTTCGACATGCAGGACGTGCTGGGCTTGCGTTAA

Upstream 100 bases:

>100_bases
CGCTCCGTCGCCGCGATACAGTGCCAGTTTCGTTTCTTGTGTCGCCGATCCACGCGCTGCCTGACAGCGCTGTGCACAGG
CGCTGTTTCTGGATGACCCC

Downstream 100 bases:

>100_bases
GCCCTGCATCGATCACGTTTTCACTCGCCGGGGCGCGACGGCCCGGCGACCGGCGAGGTCCGATGGCAAACACCGGCATC
ATCCACTATCTGCAAACCAG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MKIAIAGASGRMGRMLIETVLNDPEVKLSGALDRTGAPQLGQDAGAFLGKQTGVLMSDDIDAVLAQSDYLIDFTRPDGTL
AHIEAALRTNTKLVIGTTGFDDAQKARIRAASEKTGIVFASNFSVGVNVTMKLLEFAARHFSQGYDIEIIEAHHRHKVDA
PSGTALTMGEVIAGALGRKLEDCAVYAREGVTGERDPSTIGFSAIRGGDIVGDHTVLFAGIGERIEITHKSASRLSYAQG
ALRAVRFLEGHSNGLFDMQDVLGLR

Sequences:

>Translated_265_residues
MKIAIAGASGRMGRMLIETVLNDPEVKLSGALDRTGAPQLGQDAGAFLGKQTGVLMSDDIDAVLAQSDYLIDFTRPDGTL
AHIEAALRTNTKLVIGTTGFDDAQKARIRAASEKTGIVFASNFSVGVNVTMKLLEFAARHFSQGYDIEIIEAHHRHKVDA
PSGTALTMGEVIAGALGRKLEDCAVYAREGVTGERDPSTIGFSAIRGGDIVGDHTVLFAGIGERIEITHKSASRLSYAQG
ALRAVRFLEGHSNGLFDMQDVLGLR
>Mature_265_residues
MKIAIAGASGRMGRMLIETVLNDPEVKLSGALDRTGAPQLGQDAGAFLGKQTGVLMSDDIDAVLAQSDYLIDFTRPDGTL
AHIEAALRTNTKLVIGTTGFDDAQKARIRAASEKTGIVFASNFSVGVNVTMKLLEFAARHFSQGYDIEIIEAHHRHKVDA
PSGTALTMGEVIAGALGRKLEDCAVYAREGVTGERDPSTIGFSAIRGGDIVGDHTVLFAGIGERIEITHKSASRLSYAQG
ALRAVRFLEGHSNGLFDMQDVLGLR

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=266, Percent_Identity=58.2706766917293, Blast_Score=289, Evalue=1e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_BURP8 (B2JGX9)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001858809.1
- ProteinModelPortal:   B2JGX9
- SMR:   B2JGX9
- GeneID:   6244074
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_2591
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- ProtClustDB:   PRK00048
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28196; Mature: 28196

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIAGASGRMGRMLIETVLNDPEVKLSGALDRTGAPQLGQDAGAFLGKQTGVLMSDDI
CEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHCCCCCEEEECCH
DAVLAQSDYLIDFTRPDGTLAHIEAALRTNTKLVIGTTGFDDAQKARIRAASEKTGIVFA
HHHEECCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHEECCCCCCEEEE
SNFSVGVNVTMKLLEFAARHFSQGYDIEIIEAHHRHKVDAPSGTALTMGEVIAGALGRKL
ECCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEHHHHHHHHHCCHH
EDCAVYAREGVTGERDPSTIGFSAIRGGDIVGDHTVLFAGIGERIEITHKSASRLSYAQG
HHHHHHHHCCCCCCCCCCCCCCEEECCCCEECCCEEEEECCCCEEEEECCCHHHHHHHHH
ALRAVRFLEGHSNGLFDMQDVLGLR
HHHHHHHHHCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MKIAIAGASGRMGRMLIETVLNDPEVKLSGALDRTGAPQLGQDAGAFLGKQTGVLMSDDI
CEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHCCCCCEEEECCH
DAVLAQSDYLIDFTRPDGTLAHIEAALRTNTKLVIGTTGFDDAQKARIRAASEKTGIVFA
HHHEECCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHEECCCCCCEEEE
SNFSVGVNVTMKLLEFAARHFSQGYDIEIIEAHHRHKVDAPSGTALTMGEVIAGALGRKL
ECCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEHHHHHHHHHCCHH
EDCAVYAREGVTGERDPSTIGFSAIRGGDIVGDHTVLFAGIGERIEITHKSASRLSYAQG
HHHHHHHHCCCCCCCCCCCCCCEEECCCCEECCCEEEEECCCCEEEEECCCHHHHHHHHH
ALRAVRFLEGHSNGLFDMQDVLGLR
HHHHHHHHHCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA