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The map label for this gene is gntK [H]

Identifier: 186477325

GI number: 186477325

Start: 2898078

End: 2898572

Strand: Reverse

Name: gntK [H]

Synonym: Bphy_2577

Alternate gene names: 186477325

Gene position: 2898572-2898078 (Counterclockwise)

Preceding gene: 186477326

Following gene: 186477323

Centisome position: 83.31

GC content: 59.39

Gene sequence:

>495_bases
ATGATTTTGATCGCGATGGGCGTATCGGGCGCCGGCAAGACCCGGATTGGGGAATTGCTGGCTGAGCGGCTCAAGTGCAG
TTTCACCGACGGCGACGCGTTTCACAGCGCCGCCAACAAGGAGAAGATGCACAACGGCATTCCGTTGACGGATGAAGACC
GCTGGCCGTGGCTCAGAACGATCCGTGCGGCGATCGAAGAGAAGCAGCGGGCGGGCGAGACGGCGGTGTTCACGTGCTCG
TCGTTGAAGCGCTCGTACCGCGATATCTTGCGGGACGGAGATCGCGATGTGTGTTTTGTTTACCTGAAGGGCACGCGGGA
GTTGTTGCAGGAGCGACTGCAGACGCGGACCGGGCATTTCTTCGACCCGTCGTTGTTGCAGAGTCAGCTCGATACGCTGG
AAGAGCCAGGCGAGGATGAGGCGATTACGGTGAGTATCGAGCTGACGCCCGAAGAAATCGTGGATAAGACGCTGGCTATG
GTGAAAGCGCGTTAG

Upstream 100 bases:

>100_bases
GGGCAGACGTTTCAGACGTGGTCGCTCTGCGAAACCATCATTTCGCTGATGGGTCTGGGTTTGACCTTCGCGTTGGCGGC
GGTCCTGTAAGGAGTTTCAA

Downstream 100 bases:

>100_bases
CGTTTTACGTGGTCTGCTGCTTGTTGCGGGCCTCGGGGTCTTGTCCTGATTCGCCAGCGTTGCCCCGCAGAGGAGCAACG
CCAGCGAACCAGAAGCAAAA

Product: carbohydrate kinase

Products: NA

Alternate protein names: Gluconate kinase 2 [H]

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MILIAMGVSGAGKTRIGELLAERLKCSFTDGDAFHSAANKEKMHNGIPLTDEDRWPWLRTIRAAIEEKQRAGETAVFTCS
SLKRSYRDILRDGDRDVCFVYLKGTRELLQERLQTRTGHFFDPSLLQSQLDTLEEPGEDEAITVSIELTPEEIVDKTLAM
VKAR

Sequences:

>Translated_164_residues
MILIAMGVSGAGKTRIGELLAERLKCSFTDGDAFHSAANKEKMHNGIPLTDEDRWPWLRTIRAAIEEKQRAGETAVFTCS
SLKRSYRDILRDGDRDVCFVYLKGTRELLQERLQTRTGHFFDPSLLQSQLDTLEEPGEDEAITVSIELTPEEIVDKTLAM
VKAR
>Mature_164_residues
MILIAMGVSGAGKTRIGELLAERLKCSFTDGDAFHSAANKEKMHNGIPLTDEDRWPWLRTIRAAIEEKQRAGETAVFTCS
SLKRSYRDILRDGDRDVCFVYLKGTRELLQERLQTRTGHFFDPSLLQSQLDTLEEPGEDEAITVSIELTPEEIVDKTLAM
VKAR

Specific function: Gluconate utilization system GNT-I. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=181, Percent_Identity=38.121546961326, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI87082265, Length=163, Percent_Identity=41.7177914110429, Blast_Score=147, Evalue=3e-37,
Organism=Escherichia coli, GI1790719, Length=147, Percent_Identity=47.6190476190476, Blast_Score=138, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI25146487, Length=167, Percent_Identity=44.9101796407186, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6320454, Length=146, Percent_Identity=37.6712328767123, Blast_Score=101, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 18499; Mature: 18499

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILIAMGVSGAGKTRIGELLAERLKCSFTDGDAFHSAANKEKMHNGIPLTDEDRWPWLRT
CEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
IRAAIEEKQRAGETAVFTCSSLKRSYRDILRDGDRDVCFVYLKGTRELLQERLQTRTGHF
HHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCC
FDPSLLQSQLDTLEEPGEDEAITVSIELTPEEIVDKTLAMVKAR
CCHHHHHHHHHHHCCCCCCCEEEEEEEECHHHHHHHHHHHHCCC
>Mature Secondary Structure
MILIAMGVSGAGKTRIGELLAERLKCSFTDGDAFHSAANKEKMHNGIPLTDEDRWPWLRT
CEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
IRAAIEEKQRAGETAVFTCSSLKRSYRDILRDGDRDVCFVYLKGTRELLQERLQTRTGHF
HHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCC
FDPSLLQSQLDTLEEPGEDEAITVSIELTPEEIVDKTLAMVKAR
CCHHHHHHHHHHHCCCCCCCEEEEEEEECHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9135111; 9278503; 8655507; 11468405 [H]