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The map label for this gene is dtd

Identifier: 186477307

GI number: 186477307

Start: 2880407

End: 2880865

Strand: Reverse

Name: dtd

Synonym: Bphy_2559

Alternate gene names: 186477307

Gene position: 2880865-2880407 (Counterclockwise)

Preceding gene: 186477308

Following gene: 186477306

Centisome position: 82.8

GC content: 67.54

Gene sequence:

>459_bases
ATGATCGCGCTGATTCAACGTGTGCGGCGCGCCGAAGTGCGCGTCGGCGATCGCGTGACGGGCGCAATCGACGCGGGCCT
GCTCGCGCTAGTCTGCGCCGAGCGCGGCGACACCGATGCAGTCGCCGACAAGCTGCTCGCCAAGGTGCTGGGCTACCGCG
TGTTCAGCGACGCCGCGGGCAAGATGAACCTGCCCGTGCAGAATATCGACGGCGCGGGGCGCGCGGGCGGCCTGCTGCTC
GTTTCGCAGTTCACGCTGGCAGCCGACACGAACAGCGGCCTGCGCCCGAGCTTTACGCCCGCCGCGCCGCCAGACGAGGG
CAAGCGGTTGTTCGATTACTTCGTGGCGGCTGCGCGCGCGAAGCATGCCATCGTCGAAACGGGCGAGTTCGGAGCGGAGA
TGCAAGTTTCGCTCGTCAACGACGGCCCTGTCACTTTCTGGCTGCAGACGCGCGCATAA

Upstream 100 bases:

>100_bases
GAGTTCGTCGTGCAGGTCGGCAAACGACGTTTTGCGCGTGTCACGCTGACGGCATGATGCTCAGTCAGCCTGTGCACATG
CCACCACGCGCCCGCGTCGC

Downstream 100 bases:

>100_bases
CCGCCGTTTCCCTGCTCCCCATTCATGGCGACACAAGTTCTCTTCATCCGACACGGTGAAACCGACTGGAACCGCATCAA
GCGGATTCAAGGGCACATCG

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MIALIQRVRRAEVRVGDRVTGAIDAGLLALVCAERGDTDAVADKLLAKVLGYRVFSDAAGKMNLPVQNIDGAGRAGGLLL
VSQFTLAADTNSGLRPSFTPAAPPDEGKRLFDYFVAAARAKHAIVETGEFGAEMQVSLVNDGPVTFWLQTRA

Sequences:

>Translated_152_residues
MIALIQRVRRAEVRVGDRVTGAIDAGLLALVCAERGDTDAVADKLLAKVLGYRVFSDAAGKMNLPVQNIDGAGRAGGLLL
VSQFTLAADTNSGLRPSFTPAAPPDEGKRLFDYFVAAARAKHAIVETGEFGAEMQVSLVNDGPVTFWLQTRA
>Mature_152_residues
MIALIQRVRRAEVRVGDRVTGAIDAGLLALVCAERGDTDAVADKLLAKVLGYRVFSDAAGKMNLPVQNIDGAGRAGGLLL
VSQFTLAADTNSGLRPSFTPAAPPDEGKRLFDYFVAAARAKHAIVETGEFGAEMQVSLVNDGPVTFWLQTRA

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=154, Percent_Identity=35.0649350649351, Blast_Score=83, Evalue=8e-17,
Organism=Escherichia coli, GI1790320, Length=149, Percent_Identity=59.7315436241611, Blast_Score=170, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI115533292, Length=154, Percent_Identity=35.0649350649351, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319982, Length=152, Percent_Identity=39.4736842105263, Blast_Score=92, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281361569, Length=152, Percent_Identity=34.2105263157895, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_BURP8 (B2JGU7)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001858777.1
- ProteinModelPortal:   B2JGU7
- SMR:   B2JGU7
- GeneID:   6244042
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_2559
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16100; Mature: 16100

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: ACT_SITE 85-85

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALIQRVRRAEVRVGDRVTGAIDAGLLALVCAERGDTDAVADKLLAKVLGYRVFSDAAG
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
KMNLPVQNIDGAGRAGGLLLVSQFTLAADTNSGLRPSFTPAAPPDEGKRLFDYFVAAARA
CCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
KHAIVETGEFGAEMQVSLVNDGPVTFWLQTRA
HHHEEECCCCCCEEEEEEECCCCEEEEEEECC
>Mature Secondary Structure
MIALIQRVRRAEVRVGDRVTGAIDAGLLALVCAERGDTDAVADKLLAKVLGYRVFSDAAG
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
KMNLPVQNIDGAGRAGGLLLVSQFTLAADTNSGLRPSFTPAAPPDEGKRLFDYFVAAARA
CCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
KHAIVETGEFGAEMQVSLVNDGPVTFWLQTRA
HHHEEECCCCCCEEEEEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA