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The map label for this gene is dgk [H]

Identifier: 186477242

GI number: 186477242

Start: 2803648

End: 2804343

Strand: Direct

Name: dgk [H]

Synonym: Bphy_2493

Alternate gene names: 186477242

Gene position: 2803648-2804343 (Clockwise)

Preceding gene: 186477241

Following gene: 186477243

Centisome position: 80.58

GC content: 61.93

Gene sequence:

>696_bases
ATGAACTCCTTGCCGCTGACGGCCCCGCCACTCACCGTGACGGCGCCCGACTTGCATCCACCGCACGGCTATCTGACGAT
CGAAGGGCCGATCGGCGTCGGCAAGACTTCGCTTGCGCGCCGGCTCGCCCAACGCTGGTCGATGCACGAGCTGTTTGAGC
GTCCGCAGGACAATCCGTTTCTCGAACGCTTCTATCGCGATACGTCGCGTCATGCGTTGCCCACGCAACTAAGCTTTGCG
TTGCAACGCGCGCAGCAGACGCAGGAGATCGCCGCGCGGCGCACGGCGGGCACGCCGCTCATCACCGACTTCATGACGCA
GAAGAACGATATCTTCGCGCGCCTCACGCTGGACGACGACGAGTACCAGCTGTATCGCGCACTTGCGGCGAAGCTCGACA
CGCCGGGTCCGTCGCCCGATCTGATCGTCTATCTGCAGGCGAGCCCCGAAGTTCTGTTCTCGCGTATCCAGAAACGCGCG
GTGCCGATGGAACTGCAGATTTCGGATGCGTACCTGCGTTCGCTGTGCGACGCGTACAACGATTTCTTCTATCACTATGA
CGGCGCGCCGGTTCTCACGGTCAGCGCCGAACACCTGAACCCGCTCGAATCCGACGCGGACCTTGCTTTGCTCGTCGAAC
GCATCGAAACGATGCGCGGGCGCAAGGAATTCTTTGTCAAAGGCGGCACGCTATAG

Upstream 100 bases:

>100_bases
GCCTCGCGTCCAATGCGTCCAATGCGGCCAACGCGAGCGACGCAGCCGGCACGCTCGGCATGGCAGACAACGGGGACGAC
GCACCCAAAGGCGGCTGCCG

Downstream 100 bases:

>100_bases
CGTCCGGCTGCAGCGTGCGGCCGTATTACCAACGGACTTCCCATGACCTATTTGCAGGAGACGAGCCGCAGCGCCGTCAC
CGTCCCGAAACTGATGGCGA

Product: deoxynucleoside kinase

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MNSLPLTAPPLTVTAPDLHPPHGYLTIEGPIGVGKTSLARRLAQRWSMHELFERPQDNPFLERFYRDTSRHALPTQLSFA
LQRAQQTQEIAARRTAGTPLITDFMTQKNDIFARLTLDDDEYQLYRALAAKLDTPGPSPDLIVYLQASPEVLFSRIQKRA
VPMELQISDAYLRSLCDAYNDFFYHYDGAPVLTVSAEHLNPLESDADLALLVERIETMRGRKEFFVKGGTL

Sequences:

>Translated_231_residues
MNSLPLTAPPLTVTAPDLHPPHGYLTIEGPIGVGKTSLARRLAQRWSMHELFERPQDNPFLERFYRDTSRHALPTQLSFA
LQRAQQTQEIAARRTAGTPLITDFMTQKNDIFARLTLDDDEYQLYRALAAKLDTPGPSPDLIVYLQASPEVLFSRIQKRA
VPMELQISDAYLRSLCDAYNDFFYHYDGAPVLTVSAEHLNPLESDADLALLVERIETMRGRKEFFVKGGTL
>Mature_231_residues
MNSLPLTAPPLTVTAPDLHPPHGYLTIEGPIGVGKTSLARRLAQRWSMHELFERPQDNPFLERFYRDTSRHALPTQLSFA
LQRAQQTQEIAARRTAGTPLITDFMTQKNDIFARLTLDDDEYQLYRALAAKLDTPGPSPDLIVYLQASPEVLFSRIQKRA
VPMELQISDAYLRSLCDAYNDFFYHYDGAPVLTVSAEHLNPLESDADLALLVERIETMRGRKEFFVKGGTL

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 26147; Mature: 26147

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLPLTAPPLTVTAPDLHPPHGYLTIEGPIGVGKTSLARRLAQRWSMHELFERPQDNPF
CCCCCCCCCCCEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHHCCCCCHH
LERFYRDTSRHALPTQLSFALQRAQQTQEIAARRTAGTPLITDFMTQKNDIFARLTLDDD
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEEEECCH
EYQLYRALAAKLDTPGPSPDLIVYLQASPEVLFSRIQKRAVPMELQISDAYLRSLCDAYN
HHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHH
DFFYHYDGAPVLTVSAEHLNPLESDADLALLVERIETMRGRKEFFVKGGTL
HHEEEECCCEEEEEEHHHCCCCCCCCHHHHHHHHHHHHCCCHHEEEECCCC
>Mature Secondary Structure
MNSLPLTAPPLTVTAPDLHPPHGYLTIEGPIGVGKTSLARRLAQRWSMHELFERPQDNPF
CCCCCCCCCCCEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHHCCCCCHH
LERFYRDTSRHALPTQLSFALQRAQQTQEIAARRTAGTPLITDFMTQKNDIFARLTLDDD
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEEEECCH
EYQLYRALAAKLDTPGPSPDLIVYLQASPEVLFSRIQKRAVPMELQISDAYLRSLCDAYN
HHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHH
DFFYHYDGAPVLTVSAEHLNPLESDADLALLVERIETMRGRKEFFVKGGTL
HHEEEECCCEEEEEEHHHCCCCCCCCHHHHHHHHHHHHCCCHHEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]