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The map label for this gene is gtaB [H]

Identifier: 186477228

GI number: 186477228

Start: 2787431

End: 2788363

Strand: Reverse

Name: gtaB [H]

Synonym: Bphy_2479

Alternate gene names: 186477228

Gene position: 2788363-2787431 (Counterclockwise)

Preceding gene: 186477233

Following gene: 186477225

Centisome position: 80.14

GC content: 62.81

Gene sequence:

>933_bases
ATGCTCAGCATACGCAAGGCGGTGTTTCCCGTGGCCGGTCTCGGCACCCGATTCCTCCCGGCGACGAAGGCAAGCCCCAA
AGAAATGCTGCCCGTAGTGGACAAACCGCTCATCCAGTACGCGGTCGAAGAGGCGATCGCCGCTGGCATCACCGAAATGA
TCTTTGTCACGGGGCGCAGCAAGCGTGCGATCGAAGATCATTTTGACAAGTCGTATGAAGTCGAGTGCGAGCTGCTCGCG
CGCGGCAAGCTTGCGTTGCTCGAACTGGTGCAGAACATTAAACCGAGCCACGTCGAATGCTGTTACGTGCGCCAGCCGGA
GCCCCTCGGGCTGGGTCACGCGGTGCTCTGCGCGGAAAAACTGGTCGGCGACGAGCCGTTCGCCGTGATTCTCGCCGACG
ATCTGCTCGACGGCGAGCCGCCCGTGCTTTCGCAGATGGTGAGCCTCTTCAATCACTATCACTGCTCGATCGTCGGCGTG
GAGGAGATCGACAAGCAGGAATCGCGTTCGTATGGCGTGATCGACGGCAAGCGCTGGGACGACCGGTTGTTCAAGATGTC
CGGCATCGTCGAAAAGCCCGCGCCGGAAGACGCGCCGTCCAATCTCGGCGTGGTGGGCCGCTACGTGCTGATGCCCGCGA
TCTTCGATCGTCTGCGCCGCCAGCAGGCGGGTGCGGGCGGCGAGATCCAGCTGACGGACGCTATCCAGGCGTTGCTCGGC
AGCGAGCAGGCGCTCGCGTATCAATATGTGGGCAGGCGTTTCGACTGCGGCAGCAAGCTCGGCTATCTGAAGGCGACCGT
CGAGTTCGCGTTGCGTCATCCCGAGGTCAAGGACGCGTTCGATGCGTATCTGCACGAGCGTATGCAAGGTGGGCGCGCCG
CGGACGGCGACGGCGTGAAGGAAGAACTGGCCGAGTTGCTGAGCCGGGTGTGA

Upstream 100 bases:

>100_bases
CGAGTCTGAAATAAACGAGAAGTTGGCAGATCGGCTCGATATTCGCGGAATACGCTGGCGTATGGATGCTTATCAATCAA
CTCAACGAAGAGGCGCGAGC

Downstream 100 bases:

>100_bases
GCGTCGTGTTCGAGAGGGCGCGGCGGCAGAGTCTGCCGCGCTTTCCGTTGCCCAAGCGTTACCGCACGCGTGCGGCTCAG
CGGAAGTAGGCCTTGGTGTT

Product: UTP-glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; General stress protein 33; GSP33; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MLSIRKAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAIAAGITEMIFVTGRSKRAIEDHFDKSYEVECELLA
RGKLALLELVQNIKPSHVECCYVRQPEPLGLGHAVLCAEKLVGDEPFAVILADDLLDGEPPVLSQMVSLFNHYHCSIVGV
EEIDKQESRSYGVIDGKRWDDRLFKMSGIVEKPAPEDAPSNLGVVGRYVLMPAIFDRLRRQQAGAGGEIQLTDAIQALLG
SEQALAYQYVGRRFDCGSKLGYLKATVEFALRHPEVKDAFDAYLHERMQGGRAADGDGVKEELAELLSRV

Sequences:

>Translated_310_residues
MLSIRKAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAIAAGITEMIFVTGRSKRAIEDHFDKSYEVECELLA
RGKLALLELVQNIKPSHVECCYVRQPEPLGLGHAVLCAEKLVGDEPFAVILADDLLDGEPPVLSQMVSLFNHYHCSIVGV
EEIDKQESRSYGVIDGKRWDDRLFKMSGIVEKPAPEDAPSNLGVVGRYVLMPAIFDRLRRQQAGAGGEIQLTDAIQALLG
SEQALAYQYVGRRFDCGSKLGYLKATVEFALRHPEVKDAFDAYLHERMQGGRAADGDGVKEELAELLSRV
>Mature_310_residues
MLSIRKAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAIAAGITEMIFVTGRSKRAIEDHFDKSYEVECELLA
RGKLALLELVQNIKPSHVECCYVRQPEPLGLGHAVLCAEKLVGDEPFAVILADDLLDGEPPVLSQMVSLFNHYHCSIVGV
EEIDKQESRSYGVIDGKRWDDRLFKMSGIVEKPAPEDAPSNLGVVGRYVLMPAIFDRLRRQQAGAGGEIQLTDAIQALLG
SEQALAYQYVGRRFDCGSKLGYLKATVEFALRHPEVKDAFDAYLHERMQGGRAADGDGVKEELAELLSRV

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used as a membr

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=293, Percent_Identity=51.877133105802, Blast_Score=267, Evalue=5e-73,
Organism=Escherichia coli, GI1788355, Length=277, Percent_Identity=48.7364620938628, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1790224, Length=307, Percent_Identity=24.7557003257329, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788351, Length=269, Percent_Identity=24.907063197026, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 34140; Mature: 34140

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIRKAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAIAAGITEMIFVTGRS
CCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
KRAIEDHFDKSYEVECELLARGKLALLELVQNIKPSHVECCYVRQPEPLGLGHAVLCAEK
CHHHHHHCCCCCCEEEHHHHCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHH
LVGDEPFAVILADDLLDGEPPVLSQMVSLFNHYHCSIVGVEEIDKQESRSYGVIDGKRWD
HCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCCCCHH
DRLFKMSGIVEKPAPEDAPSNLGVVGRYVLMPAIFDRLRRQQAGAGGEIQLTDAIQALLG
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHC
SEQALAYQYVGRRFDCGSKLGYLKATVEFALRHPEVKDAFDAYLHERMQGGRAADGDGVK
CCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHH
EELAELLSRV
HHHHHHHHCC
>Mature Secondary Structure
MLSIRKAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAIAAGITEMIFVTGRS
CCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
KRAIEDHFDKSYEVECELLARGKLALLELVQNIKPSHVECCYVRQPEPLGLGHAVLCAEK
CHHHHHHCCCCCCEEEHHHHCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHH
LVGDEPFAVILADDLLDGEPPVLSQMVSLFNHYHCSIVGVEEIDKQESRSYGVIDGKRWD
HCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCCCCHH
DRLFKMSGIVEKPAPEDAPSNLGVVGRYVLMPAIFDRLRRQQAGAGGEIQLTDAIQALLG
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHC
SEQALAYQYVGRRFDCGSKLGYLKATVEFALRHPEVKDAFDAYLHERMQGGRAADGDGVK
CCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHH
EELAELLSRV
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8320212; 8126437; 9384377; 9298659 [H]