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The map label for this gene is epsA [H]

Identifier: 186477222

GI number: 186477222

Start: 2778009

End: 2779148

Strand: Reverse

Name: epsA [H]

Synonym: Bphy_2473

Alternate gene names: 186477222

Gene position: 2779148-2778009 (Counterclockwise)

Preceding gene: 186477223

Following gene: 186477221

Centisome position: 79.88

GC content: 62.11

Gene sequence:

>1140_bases
ATGAAGCAGCGATTTGGATTGGGTGTAGGTGCACCATTACTGCTGTCGGTTTCAGTGCTGCTCTCTGCATGCAGCATCGT
GCCCGGACAACGGATGGTCTCCCCGCCCACGCTGCCCGAAACGGGCGGCGAGTACAGCAGTGATCCTGAACAGAATGTTC
AGATCCCTGTTACCGACATCAATCTGAAGCTGGTGCGGGACATGAAGGGCCAGACGACGGAACTGAACCAGCAGATCGCC
GGGCTTTTCAGTACCAAACCCCCCTCCTACAAACTCGGGCCGGGCGACGTGCTGCAAATCACCGTGTGGGATCACCCGGA
ACTGGCGGCGGCCCTGGGCCAGCCGGCGCAGAACGTGAACAAGGGTGACCCCGGTCTCGGCTTCCTCGTGGATGCGGACG
GCAACATCCAGTTCCCGTACGCGGGCACGATCCACGTGGGCGGCAAGGATGCGGCCACGGTGCAGAAGGAGTTGTACCGC
AAGCTGAGCAACGTCTATTCGAAGCCCGAGGTGACGGTGCGCGTGTCGTCGTTCCGTTCTTCGCAGGTCTATGTGGACGG
CGAGGTGCATGCGCCCGGACCCGCCCAGGTCAACGACATTCCGATGTCGCTGACGGAGGCGATCAACCGTACGGGCGGCT
TCACGCCGAACGCCGATCAGAGTCACGTCGAACTCACGCGTGACGGTCACACGTACAACATCAACGTGCCCGACCTGATC
CGTCGCGGCAAGGCGCCGACGTCGATCTATCTGCAGCCGGGCGACCTGCTGCGCGTCGGCGGCCGCGATGAATATGGCGT
GTATCTGATGGGCGAAGTGAACCGGCCGGCGACCATCCTGCCGATGCGCGACGGGCGCCTGTCGCTCGCCGAAGCCTTGT
CGCAGGCGGGCAGCGTGAACCCGAACACGGCTTATGCGAAGCAACTGTTCGTGATCCGCAACTCGATGGGCGACAAGCCG
GAGATCTATCACCTCGACGCCACGTCGCCAACCTCGATGCTCCTTGCGAACCAGTTCAACCTGGAGCCGAAGGATGTCGT
CTACGTCGACAACAACGGTCTCGTGAAATTCAACCGCGTGCTGTCTCTGCTGTTGCCGGCGATCAACGCTGGCGTGACGG
CGGCATTGCTCGCGAAGTAG

Upstream 100 bases:

>100_bases
GGCGCCACGATCGTCAAGGGCTTCATTCATACCAACGCGTATTGAGACGGGAAGCAAGCCAGTGAAAAAGGACCAAGCTC
CCCTGTTAGGAGGAACTGCC

Downstream 100 bases:

>100_bases
TAAGCGGCGGGGCATGCGTTGCGCGCTTTGCATCAGCGGGGATAAGGGCGCGCAACGCTCTCAAGAGTGTTGGTCTTTGA
TGGATCACGCAAATGGCTAT

Product: polysaccharide export protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKQRFGLGVGAPLLLSVSVLLSACSIVPGQRMVSPPTLPETGGEYSSDPEQNVQIPVTDINLKLVRDMKGQTTELNQQIA
GLFSTKPPSYKLGPGDVLQITVWDHPELAAALGQPAQNVNKGDPGLGFLVDADGNIQFPYAGTIHVGGKDAATVQKELYR
KLSNVYSKPEVTVRVSSFRSSQVYVDGEVHAPGPAQVNDIPMSLTEAINRTGGFTPNADQSHVELTRDGHTYNINVPDLI
RRGKAPTSIYLQPGDLLRVGGRDEYGVYLMGEVNRPATILPMRDGRLSLAEALSQAGSVNPNTAYAKQLFVIRNSMGDKP
EIYHLDATSPTSMLLANQFNLEPKDVVYVDNNGLVKFNRVLSLLLPAINAGVTAALLAK

Sequences:

>Translated_379_residues
MKQRFGLGVGAPLLLSVSVLLSACSIVPGQRMVSPPTLPETGGEYSSDPEQNVQIPVTDINLKLVRDMKGQTTELNQQIA
GLFSTKPPSYKLGPGDVLQITVWDHPELAAALGQPAQNVNKGDPGLGFLVDADGNIQFPYAGTIHVGGKDAATVQKELYR
KLSNVYSKPEVTVRVSSFRSSQVYVDGEVHAPGPAQVNDIPMSLTEAINRTGGFTPNADQSHVELTRDGHTYNINVPDLI
RRGKAPTSIYLQPGDLLRVGGRDEYGVYLMGEVNRPATILPMRDGRLSLAEALSQAGSVNPNTAYAKQLFVIRNSMGDKP
EIYHLDATSPTSMLLANQFNLEPKDVVYVDNNGLVKFNRVLSLLLPAINAGVTAALLAK
>Mature_379_residues
MKQRFGLGVGAPLLLSVSVLLSACSIVPGQRMVSPPTLPETGGEYSSDPEQNVQIPVTDINLKLVRDMKGQTTELNQQIA
GLFSTKPPSYKLGPGDVLQITVWDHPELAAALGQPAQNVNKGDPGLGFLVDADGNIQFPYAGTIHVGGKDAATVQKELYR
KLSNVYSKPEVTVRVSSFRSSQVYVDGEVHAPGPAQVNDIPMSLTEAINRTGGFTPNADQSHVELTRDGHTYNINVPDLI
RRGKAPTSIYLQPGDLLRVGGRDEYGVYLMGEVNRPATILPMRDGRLSLAEALSQAGSVNPNTAYAKQLFVIRNSMGDKP
EIYHLDATSPTSMLLANQFNLEPKDVVYVDNNGLVKFNRVLSLLLPAINAGVTAALLAK

Specific function: Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor [H]

COG id: COG1596

COG function: function code M; Periplasmic protein involved in polysaccharide export

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BexD/CtrA/VexA family [H]

Homologues:

Organism=Escherichia coli, GI1787218, Length=368, Percent_Identity=38.0434782608696, Blast_Score=224, Evalue=9e-60,
Organism=Escherichia coli, GI1788376, Length=380, Percent_Identity=33.4210526315789, Blast_Score=204, Evalue=7e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003715
- InterPro:   IPR019554 [H]

Pfam domain/function: PF02563 Poly_export; PF10531 SLBB [H]

EC number: NA

Molecular weight: Translated: 40781; Mature: 40781

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQRFGLGVGAPLLLSVSVLLSACSIVPGQRMVSPPTLPETGGEYSSDPEQNVQIPVTDI
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
NLKLVRDMKGQTTELNQQIAGLFSTKPPSYKLGPGDVLQITVWDHPELAAALGQPAQNVN
CEEEEECCCCCHHHHHHHHHHHHCCCCCCEECCCCCEEEEEEECCCHHHHHHCCCHHHCC
KGDPGLGFLVDADGNIQFPYAGTIHVGGKDAATVQKELYRKLSNVYSKPEVTVRVSSFRS
CCCCCEEEEEECCCCEECCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
SQVYVDGEVHAPGPAQVNDIPMSLTEAINRTGGFTPNADQSHVELTRDGHTYNINVPDLI
CEEEECCEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEECCCHHHH
RRGKAPTSIYLQPGDLLRVGGRDEYGVYLMGEVNRPATILPMRDGRLSLAEALSQAGSVN
HCCCCCCEEEECCCCEEEECCCCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHCCCC
PNTAYAKQLFVIRNSMGDKPEIYHLDATSPTSMLLANQFNLEPKDVVYVDNNGLVKFNRV
CCHHHHHHEEEEHHCCCCCCEEEEECCCCCHHEEEECCCCCCCCCEEEECCCCEEEHHHH
LSLLLPAINAGVTAALLAK
HHHHHHHHCCCCEEEEECC
>Mature Secondary Structure
MKQRFGLGVGAPLLLSVSVLLSACSIVPGQRMVSPPTLPETGGEYSSDPEQNVQIPVTDI
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
NLKLVRDMKGQTTELNQQIAGLFSTKPPSYKLGPGDVLQITVWDHPELAAALGQPAQNVN
CEEEEECCCCCHHHHHHHHHHHHCCCCCCEECCCCCEEEEEEECCCHHHHHHCCCHHHCC
KGDPGLGFLVDADGNIQFPYAGTIHVGGKDAATVQKELYRKLSNVYSKPEVTVRVSSFRS
CCCCCEEEEEECCCCEECCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
SQVYVDGEVHAPGPAQVNDIPMSLTEAINRTGGFTPNADQSHVELTRDGHTYNINVPDLI
CEEEECCEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEECCCHHHH
RRGKAPTSIYLQPGDLLRVGGRDEYGVYLMGEVNRPATILPMRDGRLSLAEALSQAGSVN
HCCCCCCEEEECCCCEEEECCCCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHCCCC
PNTAYAKQLFVIRNSMGDKPEIYHLDATSPTSMLLANQFNLEPKDVVYVDNNGLVKFNRV
CCHHHHHHEEEEHHCCCCCCEEEEECCCCCHHEEEECCCCCCCCCEEEECCCCEEEHHHH
LSLLLPAINAGVTAALLAK
HHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]