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The map label for this gene is capD [H]

Identifier: 186477040

GI number: 186477040

Start: 2567515

End: 2569404

Strand: Reverse

Name: capD [H]

Synonym: Bphy_2289

Alternate gene names: 186477040

Gene position: 2569404-2567515 (Counterclockwise)

Preceding gene: 186477041

Following gene: 186477038

Centisome position: 73.85

GC content: 64.18

Gene sequence:

>1890_bases
ATGCTCAGATCCAAAGCCAGCTGGCTATCCTTCAGCGCTTTTCTGTTCGACCTGGCTGCCGTCGCCGGCACGTGGCTCAT
CGCCTACGTGATCCGTTTCAACGGCGCCGTGCCTGTGGATTTCCGCGACGGCGCGCTGCACGCGCTCATCTGGGTGCTGC
CCGTCTACGGCGTGATGTTCCGCATCTTCGGCCTGTACCGCGGCATGTGGGTGTTCGCGAGCCTGCCCGACCTGATGCGC
ATTTCGAAGGCGGTCGCAACGGGCGCGTTGCTGGCGATGATTCTCGCCGTGATGATCCAGCCGGTCCCGATCATTCCGCG
TTCGGTGCTGCTGGTCTCGCCGCTGCTGCTGTTCCTCGCGATGGGCGGCTCGCGGGCGCTGTATCGGGCGGCGAAGGAGT
TCTATCTGTACGGCGGCCTCGTCGCGCAGGGCAAGCCTGTCGTCGTGATTGGCGCGGGCACGGCGGGCGCGATGCTCGCG
CGCGAACTGTCCCGTTCGAGCGAATGGCGCCTGATCGGTTTGCTGGATGACGACGTGTCAAAGCAGGGCCGCGAGATTTA
CGGCTACAAGGTGCTCGGCCCGATCAGCAAGCTGCCGGAAATCGCCGAGGCGATGAAGACGGAGTACGCGATCATCGCGA
TTCCTTCGGCGCCCGTCGAACAACAGCGCCGCGCGGCCACGCTGTGCGTGCGCGCTGGCGTGCGCGCGATGGTGCTGCCC
GCACTGACGGATATGACGGAAGGGCAGGCGTCGATGTCGCGCGTGCGTCATATCGATCTGGAAGATCTGCTCGGACGCGA
GCCCGTGCATATCGACACGCCGCACGTCGAAGCGCTGCTGCATGCGCGCGTCGTGATGGTGACGGGCGCGGGCGGATCGA
TCGGCTCGGAGCTGTGCCGCCAGATCCTGCGCTTCAAGCCCGCCCAACTGATCGCCTTCGATATCTCCGAGTACGCGATG
TACCGCTTGGTCGAAGAGTTGCTCGAACGCTTTCCGGGGCTTTCCATCGTGCCGGTGATCGGTGACGCGAAGGATTCACT
GCTGCTCGATCAGGTGATGGCGCGCTTCACGCCGCACATCGTCTATCACGCGGCCGCCTACAAACACGTCCCGCTGATGG
AAGAGCAGAACGCATGGCAGGCCGTGCGCAACAACGTGCTCGGCACCTACCGCGTCGCGCGCGCAGCGATTCGCCATGAC
GTGAAGCGCTTCGTGCTGATTTCGACCGACAAGGCCGTCAATCCGACCAACGTGATGGGCGCGAGCAAGCGTCTCGCGGA
AATGGCGTGTCAGGCGCTGCAGCAGACCAGCGAGCGCACGCAGTTCGAAACAGTGCGCTTCGGCAACGTGCTCGGCAGCG
CGGGCAGCGTGATCCCCAAGTTCCAGCAGCAGATCGCGAAGGGTGGCCCCGTCACGGTCACGCACCCGGAAATCACGCGC
TTTTTCATGACGATTCCGGAGGCGTCGCAGCTCGTGCTGCAGGCATCGAGCATGGGTCACGGCGGCGAAATCTTCATTCT
CGACATGGGCGAGCCGATGAAGATCGTCGATCTCGCGCGCGACCTGATCCGTCTGTACGGATTCACCGAAGAACAGATCC
GTATCGAGTTCACGGGTTTGCGCCCCGGTGAAAAGCTCTATGAAGAATTACTCGCCGACGAGGAAACCACAACGCGCACG
CCGCATCCGAAGCTGCGTATCGCCCAGGCGCGCGGCGTGCCCGACAATCTGCTCGACGAACTGTTGCCGTGGCTGATGCA
GCATCGCGTGCTGACGGACGACGAAGTGCGCCGCGATCTGCGGCGCTGGGTTACCGAATATCAGCCGACGCTGGCCGCGC
CGCCGCTGCGCAGCGTGCCGCCGCCAGCGGGCAAGCGGGCATTGATGTAA

Upstream 100 bases:

>100_bases
CGGGATGGGCCGGCGTGCTGGTCGTCGTCGGAAGCATCGTCGATCTGCGCTGGCGCCGTTTCCAGTCCACACTGTGCAAA
CAATCCGAGGTATGACGCTG

Downstream 100 bases:

>100_bases
CGAAAAAGGCGCCGAGGCGCCTTTTTTCATGTCTGTCGCCGGGGGGCCGTTCGGATCGCCAGGCAAGCTGCAGCTTACCT
GGTGCTTACCTGGTGTCAGA

Product: polysaccharide biosynthesis protein CapD

Products: UDPglucoseal [C]

Alternate protein names: NA

Number of amino acids: Translated: 629; Mature: 629

Protein sequence:

>629_residues
MLRSKASWLSFSAFLFDLAAVAGTWLIAYVIRFNGAVPVDFRDGALHALIWVLPVYGVMFRIFGLYRGMWVFASLPDLMR
ISKAVATGALLAMILAVMIQPVPIIPRSVLLVSPLLLFLAMGGSRALYRAAKEFYLYGGLVAQGKPVVVIGAGTAGAMLA
RELSRSSEWRLIGLLDDDVSKQGREIYGYKVLGPISKLPEIAEAMKTEYAIIAIPSAPVEQQRRAATLCVRAGVRAMVLP
ALTDMTEGQASMSRVRHIDLEDLLGREPVHIDTPHVEALLHARVVMVTGAGGSIGSELCRQILRFKPAQLIAFDISEYAM
YRLVEELLERFPGLSIVPVIGDAKDSLLLDQVMARFTPHIVYHAAAYKHVPLMEEQNAWQAVRNNVLGTYRVARAAIRHD
VKRFVLISTDKAVNPTNVMGASKRLAEMACQALQQTSERTQFETVRFGNVLGSAGSVIPKFQQQIAKGGPVTVTHPEITR
FFMTIPEASQLVLQASSMGHGGEIFILDMGEPMKIVDLARDLIRLYGFTEEQIRIEFTGLRPGEKLYEELLADEETTTRT
PHPKLRIAQARGVPDNLLDELLPWLMQHRVLTDDEVRRDLRRWVTEYQPTLAAPPLRSVPPPAGKRALM

Sequences:

>Translated_629_residues
MLRSKASWLSFSAFLFDLAAVAGTWLIAYVIRFNGAVPVDFRDGALHALIWVLPVYGVMFRIFGLYRGMWVFASLPDLMR
ISKAVATGALLAMILAVMIQPVPIIPRSVLLVSPLLLFLAMGGSRALYRAAKEFYLYGGLVAQGKPVVVIGAGTAGAMLA
RELSRSSEWRLIGLLDDDVSKQGREIYGYKVLGPISKLPEIAEAMKTEYAIIAIPSAPVEQQRRAATLCVRAGVRAMVLP
ALTDMTEGQASMSRVRHIDLEDLLGREPVHIDTPHVEALLHARVVMVTGAGGSIGSELCRQILRFKPAQLIAFDISEYAM
YRLVEELLERFPGLSIVPVIGDAKDSLLLDQVMARFTPHIVYHAAAYKHVPLMEEQNAWQAVRNNVLGTYRVARAAIRHD
VKRFVLISTDKAVNPTNVMGASKRLAEMACQALQQTSERTQFETVRFGNVLGSAGSVIPKFQQQIAKGGPVTVTHPEITR
FFMTIPEASQLVLQASSMGHGGEIFILDMGEPMKIVDLARDLIRLYGFTEEQIRIEFTGLRPGEKLYEELLADEETTTRT
PHPKLRIAQARGVPDNLLDELLPWLMQHRVLTDDEVRRDLRRWVTEYQPTLAAPPLRSVPPPAGKRALM
>Mature_629_residues
MLRSKASWLSFSAFLFDLAAVAGTWLIAYVIRFNGAVPVDFRDGALHALIWVLPVYGVMFRIFGLYRGMWVFASLPDLMR
ISKAVATGALLAMILAVMIQPVPIIPRSVLLVSPLLLFLAMGGSRALYRAAKEFYLYGGLVAQGKPVVVIGAGTAGAMLA
RELSRSSEWRLIGLLDDDVSKQGREIYGYKVLGPISKLPEIAEAMKTEYAIIAIPSAPVEQQRRAATLCVRAGVRAMVLP
ALTDMTEGQASMSRVRHIDLEDLLGREPVHIDTPHVEALLHARVVMVTGAGGSIGSELCRQILRFKPAQLIAFDISEYAM
YRLVEELLERFPGLSIVPVIGDAKDSLLLDQVMARFTPHIVYHAAAYKHVPLMEEQNAWQAVRNNVLGTYRVARAAIRHD
VKRFVLISTDKAVNPTNVMGASKRLAEMACQALQQTSERTQFETVRFGNVLGSAGSVIPKFQQQIAKGGPVTVTHPEITR
FFMTIPEASQLVLQASSMGHGGEIFILDMGEPMKIVDLARDLIRLYGFTEEQIRIEFTGLRPGEKLYEELLADEETTTRT
PHPKLRIAQARGVPDNLLDELLPWLMQHRVLTDDEVRRDLRRWVTEYQPTLAAPPLRSVPPPAGKRALM

Specific function: Required for the biosynthesis of type 1 capsular polysaccharide [H]

COG id: COG1086

COG function: function code MG; Predicted nucleoside-diphosphate sugar epimerases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR003869 [H]

Pfam domain/function: PF02719 Polysacc_synt_2 [H]

EC number: 5.1.3.2 [C]

Molecular weight: Translated: 69705; Mature: 69705

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRSKASWLSFSAFLFDLAAVAGTWLIAYVIRFNGAVPVDFRDGALHALIWVLPVYGVMF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
RIFGLYRGMWVFASLPDLMRISKAVATGALLAMILAVMIQPVPIIPRSVLLVSPLLLFLA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
MGGSRALYRAAKEFYLYGGLVAQGKPVVVIGAGTAGAMLARELSRSSEWRLIGLLDDDVS
CCCCHHHHHHHHHHHHCCCEEECCCCEEEEECCCHHHHHHHHHCCCCCEEEEEEECCCHH
KQGREIYGYKVLGPISKLPEIAEAMKTEYAIIAIPSAPVEQQRRAATLCVRAGVRAMVLP
HCCCEEECEEECCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHCHHHHHHH
ALTDMTEGQASMSRVRHIDLEDLLGREPVHIDTPHVEALLHARVVMVTGAGGSIGSELCR
HHHHCCCCHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHCEEEEEECCCCCHHHHHHH
QILRFKPAQLIAFDISEYAMYRLVEELLERFPGLSIVPVIGDAKDSLLLDQVMARFTPHI
HHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCHHH
VYHAAAYKHVPLMEEQNAWQAVRNNVLGTYRVARAAIRHDVKRFVLISTDKAVNPTNVMG
HHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHH
ASKRLAEMACQALQQTSERTQFETVRFGNVLGSAGSVIPKFQQQIAKGGPVTVTHPEITR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEECHHHHH
FFMTIPEASQLVLQASSMGHGGEIFILDMGEPMKIVDLARDLIRLYGFTEEQIRIEFTGL
HHHCCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEECC
RPGEKLYEELLADEETTTRTPHPKLRIAQARGVPDNLLDELLPWLMQHRVLTDDEVRRDL
CCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
RRWVTEYQPTLAAPPLRSVPPPAGKRALM
HHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLRSKASWLSFSAFLFDLAAVAGTWLIAYVIRFNGAVPVDFRDGALHALIWVLPVYGVMF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
RIFGLYRGMWVFASLPDLMRISKAVATGALLAMILAVMIQPVPIIPRSVLLVSPLLLFLA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
MGGSRALYRAAKEFYLYGGLVAQGKPVVVIGAGTAGAMLARELSRSSEWRLIGLLDDDVS
CCCCHHHHHHHHHHHHCCCEEECCCCEEEEECCCHHHHHHHHHCCCCCEEEEEEECCCHH
KQGREIYGYKVLGPISKLPEIAEAMKTEYAIIAIPSAPVEQQRRAATLCVRAGVRAMVLP
HCCCEEECEEECCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHCHHHHHHH
ALTDMTEGQASMSRVRHIDLEDLLGREPVHIDTPHVEALLHARVVMVTGAGGSIGSELCR
HHHHCCCCHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHCEEEEEECCCCCHHHHHHH
QILRFKPAQLIAFDISEYAMYRLVEELLERFPGLSIVPVIGDAKDSLLLDQVMARFTPHI
HHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCHHH
VYHAAAYKHVPLMEEQNAWQAVRNNVLGTYRVARAAIRHDVKRFVLISTDKAVNPTNVMG
HHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHH
ASKRLAEMACQALQQTSERTQFETVRFGNVLGSAGSVIPKFQQQIAKGGPVTVTHPEITR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEECHHHHH
FFMTIPEASQLVLQASSMGHGGEIFILDMGEPMKIVDLARDLIRLYGFTEEQIRIEFTGL
HHHCCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEECC
RPGEKLYEELLADEETTTRTPHPKLRIAQARGVPDNLLDELLPWLMQHRVLTDDEVRRDL
CCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
RRWVTEYQPTLAAPPLRSVPPPAGKRALM
HHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): 57600 [C]

Specific activity: 233.3

Km value (mM): 0.256 {UDPgalactose}} 0.225 {UDPgalactose}} 0.2 {UDPgalactose}} 0.18 {UDPgalactose}} 0.16 {UDPgalactose}} 0.14 {UDPgalactose}} 0.048 {UDPgalactose}} 0.026 {UDPgalactose}} [C]

Substrates: UDPglucose [C]

Specific reaction: UDPglucose <==> UDPglucoseal [C]

General reaction: Epimerization (specificity for carbon forming a hexosulose) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961465 [H]