Click here to switch to the map view.

The map label for this gene is panD

Identifier: 186476949

GI number: 186476949

Start: 2472977

End: 2473363

Strand: Direct

Name: panD

Synonym: Bphy_2198

Alternate gene names: 186476949

Gene position: 2472977-2473363 (Clockwise)

Preceding gene: 186476948

Following gene: 186476951

Centisome position: 71.08

GC content: 60.47

Gene sequence:

>387_bases
ATGCAACGCAACATGCTGAAGTCGAAGATTCACCGCGCGGTGGTCACGCACTGCGAATTGCACTACGAAGGGTCGTGTGC
GATCGACGAGAACCTGCTCGAAGCGGCGAATATCGTCGAAAACGAGCGCATTGACATCTGGAACATCAACAACGGCGAGC
GCTTTTCGACGTATGCGATCAAGGGCGAGCGCGGCAGCGGCATGATCTCGCTGAACGGCTCGGCGGCGCGCCGCGCGCAA
CTGGGCGACCTGGTGATCATCGCGGCGTTCGCCAACGTCGACGAGGAAGAACTCAAGGCGGGATGGAAGCCGGATCTGGT
GTTCGTCGACGACAAGAACGCGATCAAGGGCAGCCGCGATCACGTGCCGACGCAAAGCTGGACCTGA

Upstream 100 bases:

>100_bases
GCAGGACCTGGATGCGCCGCTCGTCGTGCTGGCGGCGGCCAAGCTCGGCGCGACGCGCCTCATCGACAACCTCGAAATCT
GACGGCCGGAAGGACAAGCC

Downstream 100 bases:

>100_bases
GCGCCGCGGCCGACGGGCCGCCGCAGTTGCACACGGGCTGACGATGCGCGAGCCGCGCGTTCAGCCCTTTTTATTTGCGC
CCTTGCCGTTCGCGGCCTTG

Product: aspartate alpha-decarboxylase

Products: NA

Alternate protein names: Aspartate alpha-decarboxylase

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MQRNMLKSKIHRAVVTHCELHYEGSCAIDENLLEAANIVENERIDIWNINNGERFSTYAIKGERGSGMISLNGSAARRAQ
LGDLVIIAAFANVDEEELKAGWKPDLVFVDDKNAIKGSRDHVPTQSWT

Sequences:

>Translated_128_residues
MQRNMLKSKIHRAVVTHCELHYEGSCAIDENLLEAANIVENERIDIWNINNGERFSTYAIKGERGSGMISLNGSAARRAQ
LGDLVIIAAFANVDEEELKAGWKPDLVFVDDKNAIKGSRDHVPTQSWT
>Mature_128_residues
MQRNMLKSKIHRAVVTHCELHYEGSCAIDENLLEAANIVENERIDIWNINNGERFSTYAIKGERGSGMISLNGSAARRAQ
LGDLVIIAAFANVDEEELKAGWKPDLVFVDDKNAIKGSRDHVPTQSWT

Specific function: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine

COG id: COG0853

COG function: function code H; Aspartate 1-decarboxylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the panD family

Homologues:

Organism=Escherichia coli, GI1786323, Length=125, Percent_Identity=53.6, Blast_Score=147, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAND_BURP8 (B2JEQ8)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001858419.1
- ProteinModelPortal:   B2JEQ8
- SMR:   B2JEQ8
- GeneID:   6243684
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_2198
- HOGENOM:   HBG302821
- OMA:   LYSKIHR
- ProtClustDB:   PRK05449
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00446
- InterPro:   IPR009010
- InterPro:   IPR003190
- Gene3D:   G3DSA:2.40.40.20
- PANTHER:   PTHR21012
- PIRSF:   PIRSF006246
- ProDom:   PD009294
- TIGRFAMs:   TIGR00223

Pfam domain/function: PF02261 Asp_decarbox; SSF50692 Asp_decarb_fold

EC number: =4.1.1.11

Molecular weight: Translated: 14295; Mature: 14295

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: ACT_SITE 25-25 ACT_SITE 58-58 BINDING 57-57

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRNMLKSKIHRAVVTHCELHYEGSCAIDENLLEAANIVENERIDIWNINNGERFSTYAI
CCCHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCEEEEEEE
KGERGSGMISLNGSAARRAQLGDLVIIAAFANVDEEELKAGWKPDLVFVDDKNAIKGSRD
ECCCCCEEEEECCCCCCHHCCCCEEEEEEECCCCHHHHHCCCCCCEEEEECCCCCCCCCC
HVPTQSWT
CCCCCCCC
>Mature Secondary Structure
MQRNMLKSKIHRAVVTHCELHYEGSCAIDENLLEAANIVENERIDIWNINNGERFSTYAI
CCCHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCEEEEEEE
KGERGSGMISLNGSAARRAQLGDLVIIAAFANVDEEELKAGWKPDLVFVDDKNAIKGSRD
ECCCCCEEEEECCCCCCHHCCCCEEEEEEECCCCHHHHHCCCCCCEEEEECCCCCCCCCC
HVPTQSWT
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA