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The map label for this gene is mrp [H]

Identifier: 186476940

GI number: 186476940

Start: 2457140

End: 2458228

Strand: Reverse

Name: mrp [H]

Synonym: Bphy_2189

Alternate gene names: 186476940

Gene position: 2458228-2457140 (Counterclockwise)

Preceding gene: 186476944

Following gene: 186476939

Centisome position: 70.66

GC content: 64.19

Gene sequence:

>1089_bases
ATGAGCATCGATCGGGCTTTGGTCGACGCGGCCCTCGCGGCCATCACCGACCCCAACACCCAGCGGCCCTTCGCAGCAGC
GAAGAACTTCCGGAACGTGAACGTCGATGGTGCCACGGTCAGTGTCGACGTGGTACTCGGCTATCCGGCCAAACGCCAGT
TCGACGCGATTCGCGCGCTGGTCGAGAGTGCGCTGCGTGCGGTGCCCGGCGTCGCCGATACGCGCGTGCAGGTCTCGCAG
GACATCGCGGCGCATACCGTGCAACGCGGGGTGAAACTGTTGCCGAACGTGAAGAACATCGTCGCCGTTGCGTCGGGCAA
GGGCGGCGTCGGCAAGAGCACGACGGCTGTGAACCTGGCGCTTGCGCTCGCGAGCGAGGGCGCGTCGGTGGGCATTCTTG
ATGCGGACATCTACGGTCCGTCGCTGCCGATGATGCTGGGCATCGAAGGCCGCCCCGAGTCGCCCGACGGCCAGTCGATG
AACCCGATGACCGGCCACGGCGTGCAGGCGAACTCGATCGGCTTTCTGATCGAACAGGATAATCCGATGGTATGGCGCGG
CCCGATGGCGACGTCGGCGCTCGAGCAGTTGCTGCGCCAGACGGCCTGGAAAGATCTCGATTATCTGATCGTCGACATGC
CGCCGGGCACGGGCGACATCCAGCTCACGCTATCGCAGCGCGTGCCCGTGACGGGCGCTGTCATCGTCACGACGCCACAG
GACATTGCGCTGCTCGACGCGAAGAAGGGCTTGAAGATGTTCGAGAAGGTGGGCATTCCGATTCTCGGCATTGTCGAGAA
CATGGGCCTGCATATCTGCTCGAACTGCGGCCACGAGGAGCACATCTTCGGCACGGGCGGCGCGGAGCGCATGTCGAAGG
AATATGGTGTCGACGTGCTGGGAAGTCTGCCTCTCGACATCTCGATCCGCGAGCAGGCCGACTCGGGCCAGCCGACGGTC
GTCGCGGATCCGGATGGTCGCGTCGCGGAGATCTATCGGTCGATTGCGCGCAAGGTCGCGATTCATATCGCCGAGCGCTC
GCGCGACATGAGTTCGAAGTTCCCGACCATCGTCGTGCAGAACACATGA

Upstream 100 bases:

>100_bases
CAGGCTTTAGGCAATGCCGGCTAACAATTTCTTTCAATATTTCAGGCGCGCGGCGCAGACTTCGATCGCGCACCGCGCCC
AGCGTTCCCACGGAGACTCA

Downstream 100 bases:

>100_bases
CACGCATGCTGCTGCATCGCTGCGCGGAGCGGGAAGCGTCCGCGTAGCGCGCTGCACGCGATAACCGAACAACGCCTCGG
GGGTGGGTAGAAAGGGGTCT

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MSIDRALVDAALAAITDPNTQRPFAAAKNFRNVNVDGATVSVDVVLGYPAKRQFDAIRALVESALRAVPGVADTRVQVSQ
DIAAHTVQRGVKLLPNVKNIVAVASGKGGVGKSTTAVNLALALASEGASVGILDADIYGPSLPMMLGIEGRPESPDGQSM
NPMTGHGVQANSIGFLIEQDNPMVWRGPMATSALEQLLRQTAWKDLDYLIVDMPPGTGDIQLTLSQRVPVTGAVIVTTPQ
DIALLDAKKGLKMFEKVGIPILGIVENMGLHICSNCGHEEHIFGTGGAERMSKEYGVDVLGSLPLDISIREQADSGQPTV
VADPDGRVAEIYRSIARKVAIHIAERSRDMSSKFPTIVVQNT

Sequences:

>Translated_362_residues
MSIDRALVDAALAAITDPNTQRPFAAAKNFRNVNVDGATVSVDVVLGYPAKRQFDAIRALVESALRAVPGVADTRVQVSQ
DIAAHTVQRGVKLLPNVKNIVAVASGKGGVGKSTTAVNLALALASEGASVGILDADIYGPSLPMMLGIEGRPESPDGQSM
NPMTGHGVQANSIGFLIEQDNPMVWRGPMATSALEQLLRQTAWKDLDYLIVDMPPGTGDIQLTLSQRVPVTGAVIVTTPQ
DIALLDAKKGLKMFEKVGIPILGIVENMGLHICSNCGHEEHIFGTGGAERMSKEYGVDVLGSLPLDISIREQADSGQPTV
VADPDGRVAEIYRSIARKVAIHIAERSRDMSSKFPTIVVQNT
>Mature_361_residues
SIDRALVDAALAAITDPNTQRPFAAAKNFRNVNVDGATVSVDVVLGYPAKRQFDAIRALVESALRAVPGVADTRVQVSQD
IAAHTVQRGVKLLPNVKNIVAVASGKGGVGKSTTAVNLALALASEGASVGILDADIYGPSLPMMLGIEGRPESPDGQSMN
PMTGHGVQANSIGFLIEQDNPMVWRGPMATSALEQLLRQTAWKDLDYLIVDMPPGTGDIQLTLSQRVPVTGAVIVTTPQD
IALLDAKKGLKMFEKVGIPILGIVENMGLHICSNCGHEEHIFGTGGAERMSKEYGVDVLGSLPLDISIREQADSGQPTVV
ADPDGRVAEIYRSIARKVAIHIAERSRDMSSKFPTIVVQNT

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=250, Percent_Identity=53.6, Blast_Score=278, Evalue=6e-75,
Organism=Homo sapiens, GI118572611, Length=270, Percent_Identity=40.3703703703704, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI6912540, Length=253, Percent_Identity=39.5256916996047, Blast_Score=178, Evalue=6e-45,
Organism=Escherichia coli, GI87082045, Length=340, Percent_Identity=55.2941176470588, Blast_Score=365, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI25143050, Length=255, Percent_Identity=39.6078431372549, Blast_Score=188, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6322188, Length=259, Percent_Identity=36.6795366795367, Blast_Score=182, Evalue=6e-47,
Organism=Saccharomyces cerevisiae, GI6321347, Length=265, Percent_Identity=40, Blast_Score=172, Evalue=8e-44,
Organism=Drosophila melanogaster, GI221511043, Length=250, Percent_Identity=41.2, Blast_Score=215, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24667611, Length=256, Percent_Identity=42.1875, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI19921440, Length=242, Percent_Identity=39.6694214876033, Blast_Score=152, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR000808 [H]

Pfam domain/function: PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 38345; Mature: 38213

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDRALVDAALAAITDPNTQRPFAAAKNFRNVNVDGATVSVDVVLGYPAKRQFDAIRAL
CCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHH
VESALRAVPGVADTRVQVSQDIAAHTVQRGVKLLPNVKNIVAVASGKGGVGKSTTAVNLA
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHEEEE
LALASEGASVGILDADIYGPSLPMMLGIEGRPESPDGQSMNPMTGHGVQANSIGFLIEQD
EEEECCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEECCEEEEEECC
NPMVWRGPMATSALEQLLRQTAWKDLDYLIVDMPPGTGDIQLTLSQRVPVTGAVIVTTPQ
CCEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCEEEEEEEECCC
DIALLDAKKGLKMFEKVGIPILGIVENMGLHICSNCGHEEHIFGTGGAERMSKEYGVDVL
CEEEEEHHHHHHHHHHCCCCCEEHHHHCCHHHHHCCCCCCEEEECCCHHHHHHHCCCEEE
GSLPLDISIREQADSGQPTVVADPDGRVAEIYRSIARKVAIHIAERSRDMSSKFPTIVVQ
ECCCCCEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEE
NT
CC
>Mature Secondary Structure 
SIDRALVDAALAAITDPNTQRPFAAAKNFRNVNVDGATVSVDVVLGYPAKRQFDAIRAL
CHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHH
VESALRAVPGVADTRVQVSQDIAAHTVQRGVKLLPNVKNIVAVASGKGGVGKSTTAVNLA
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHEEEE
LALASEGASVGILDADIYGPSLPMMLGIEGRPESPDGQSMNPMTGHGVQANSIGFLIEQD
EEEECCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEECCEEEEEECC
NPMVWRGPMATSALEQLLRQTAWKDLDYLIVDMPPGTGDIQLTLSQRVPVTGAVIVTTPQ
CCEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCEEEEEEEECCC
DIALLDAKKGLKMFEKVGIPILGIVENMGLHICSNCGHEEHIFGTGGAERMSKEYGVDVL
CEEEEEHHHHHHHHHHCCCCCEEHHHHCCHHHHHCCCCCCEEEECCCHHHHHHHCCCEEE
GSLPLDISIREQADSGQPTVVADPDGRVAEIYRSIARKVAIHIAERSRDMSSKFPTIVVQ
ECCCCCEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEE
NT
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]