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The map label for this gene is htpG [H]

Identifier: 186476867

GI number: 186476867

Start: 2370137

End: 2372029

Strand: Reverse

Name: htpG [H]

Synonym: Bphy_2113

Alternate gene names: 186476867

Gene position: 2372029-2370137 (Counterclockwise)

Preceding gene: 186476868

Following gene: 186476865

Centisome position: 68.18

GC content: 61.12

Gene sequence:

>1893_bases
ATGGCACAAGAAACCATGAGCTTCCAGGCGGAAGTGAAACAGCTTCTGCATCTGATGATTCATTCGCTGTACAGCAACAA
GGAAATCTTCCTGCGCGAACTGATTTCGAACGCATCGGACGCGGCCGACAAGCTGCGCTTCGAAGCGATCGAAAATAGCG
CGCTGTATGAAAACGACCCGAACCTGCGCATTCGCGTGTCGTTCGACAAGAACGCCCGCACCATCACCATCGACGACAAC
GGCATCGGCATGAGCCGCGACGAGGCGGTCGCCAACCTCGGCACGATCGCGCGCTCCGGCACGAAGGAATTCTTCGGCAA
GCTCTCCGGCGACCAGCAAAAAGACGCGGCGCTGATCGGCCAGTTCGGCGTCGGCTTCTACTCGGGCTTCATCGTCGCGG
ACAAGATCACGGTGGAGACGCGCCGGGCGGGCCTGCCCGCAGCGGAAGGCGTGCGCTGGGTGAGCGCGGGCGAGGGCGAC
TTCTCGGTTGAAACGATCGAGCGCGCGCAGCGTGGCACGACCATCACACTGCATCTGCGCGCCGACGAAGACGAACTGCT
GTCCACCTACAAGCTCAAGTCGATCATCCAGAAGTATTCGGATCACGTCGCGCTGCCCATCCTGATGCAGAAGGAGGAGT
GGGACGCGGAAAAGAGCGAGATGGTCGCGAAGGACGAAGACGAGACCGTCAACCAGGCGAGCGCGCTGTGGACGCGGGCG
AAGAGCGACATCACGGATGAGCAGTACAAGCAGTTCTATCAACACCTGTCGCACGATCATCAGGATCCGCTGACGTGGAC
GCATAACCGCGTCGAAGGCCGCAGCGAGTACACGCAGCTGCTGTACGTGCCGGCACATGCGCCGTTCGACATGTGGAACC
GCGATCATCGCGGCGGCCTGAAGCTGTACGTGAAGCGCGTCTTCATCATGGACGACGCCGAGCAATTGCTGCCCACGTAT
CTGCGCTTTGTGAAGGGCGTGGTCGATTCGGCGGATCTGCCGCTGAACGTGTCGCGCGAACTGCTTCAGGAAAGCCGCGA
CGTGAAGGCGATCCGCGAAGGCGTGACCAAGCGCGCGCTGTCGATGCTTGAAGAGCTGGCGAACACGGAAGAAGCCGAAG
GCAAAGAAAAGTACGCGACCTTCTGGAAGGAATTCGGGCAGGTGCTGAAGGAGGGCATCGGCGAAGACTTCGCGAACAAG
GAACGCATCGCCAAGCTCGCCCGTTTCGCGTCGACGCACAACGACTCGTCCGAACAGAACGTGTCGCTGGCGGACTACGT
CGCGCGCATGAAGCCCGAGCAGTCGAAGATTTACTACGTCACGGCGGATACGTACCAGGCCGCGAAGAACAGCCCGCACC
TCGAAGTGTTCCGCAAGAAGGGCGTCGAAGTGCTGCTGCTGACGGATCGCGTCGACGAATGGATGCTGTCGTTCCTGAAC
GAGTTCGACGGCAAGCCGCTGCAAAGCGTCGCGCGCGGCGACCTCGATCTGGGTCAGTTGAACGATGAAGAAAAACAGGC
GCAGGAAAAGGTCAGCGAAGAACTGAAGCCGCTGGTCGAGCGCATGAAGGAAGCGCTCAAGGACAAGGCGAAGGACGTGC
GCCTGACTTTCCGCCTGACGGACTCGCCGTCGTGTCTCGTCGCCGACGAGGGCGACATGAGCGGCTACCTGCAGCGCATG
CTGAAGGCGGCCGGCCAGAACGCGCCGACCTTCCATCCGATTCTCGAAGTGAACCCGGAACACGCGCTGGTCAAGAGCCT
CAGCACCGACAACGCGCATTTCGACGACTGGTGCCATCTGTTGTTCGACCAGGCGCTGCTCGCGGAAGGCGGCTCGCTGG
AAGATCCGGCAAGCTTCGTGAAGCGGACCAATGCGCTGTTGCTGGCGCGCTGA

Upstream 100 bases:

>100_bases
CCCCCATTTAACAGCGCATCGTCTGTAGCGCGCGCTGTCCGTACAGATGCATTCAGCCTCGTACCCCGAATCAACCTGCA
ATAGAAGAGGAACACTGACC

Downstream 100 bases:

>100_bases
TGTGTTTGCGTCGATAACCCGTCCGGGATGGTAAAAATGCGCTGCTTCGGCAGCGCATTTTTTTGCCTGCTACGCCGGCC
GCGCGAAGTCAGCGCACCGG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 630; Mature: 629

Protein sequence:

>630_residues
MAQETMSFQAEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFEAIENSALYENDPNLRIRVSFDKNARTITIDDN
GIGMSRDEAVANLGTIARSGTKEFFGKLSGDQQKDAALIGQFGVGFYSGFIVADKITVETRRAGLPAAEGVRWVSAGEGD
FSVETIERAQRGTTITLHLRADEDELLSTYKLKSIIQKYSDHVALPILMQKEEWDAEKSEMVAKDEDETVNQASALWTRA
KSDITDEQYKQFYQHLSHDHQDPLTWTHNRVEGRSEYTQLLYVPAHAPFDMWNRDHRGGLKLYVKRVFIMDDAEQLLPTY
LRFVKGVVDSADLPLNVSRELLQESRDVKAIREGVTKRALSMLEELANTEEAEGKEKYATFWKEFGQVLKEGIGEDFANK
ERIAKLARFASTHNDSSEQNVSLADYVARMKPEQSKIYYVTADTYQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLN
EFDGKPLQSVARGDLDLGQLNDEEKQAQEKVSEELKPLVERMKEALKDKAKDVRLTFRLTDSPSCLVADEGDMSGYLQRM
LKAAGQNAPTFHPILEVNPEHALVKSLSTDNAHFDDWCHLLFDQALLAEGGSLEDPASFVKRTNALLLAR

Sequences:

>Translated_630_residues
MAQETMSFQAEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFEAIENSALYENDPNLRIRVSFDKNARTITIDDN
GIGMSRDEAVANLGTIARSGTKEFFGKLSGDQQKDAALIGQFGVGFYSGFIVADKITVETRRAGLPAAEGVRWVSAGEGD
FSVETIERAQRGTTITLHLRADEDELLSTYKLKSIIQKYSDHVALPILMQKEEWDAEKSEMVAKDEDETVNQASALWTRA
KSDITDEQYKQFYQHLSHDHQDPLTWTHNRVEGRSEYTQLLYVPAHAPFDMWNRDHRGGLKLYVKRVFIMDDAEQLLPTY
LRFVKGVVDSADLPLNVSRELLQESRDVKAIREGVTKRALSMLEELANTEEAEGKEKYATFWKEFGQVLKEGIGEDFANK
ERIAKLARFASTHNDSSEQNVSLADYVARMKPEQSKIYYVTADTYQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLN
EFDGKPLQSVARGDLDLGQLNDEEKQAQEKVSEELKPLVERMKEALKDKAKDVRLTFRLTDSPSCLVADEGDMSGYLQRM
LKAAGQNAPTFHPILEVNPEHALVKSLSTDNAHFDDWCHLLFDQALLAEGGSLEDPASFVKRTNALLLAR
>Mature_629_residues
AQETMSFQAEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFEAIENSALYENDPNLRIRVSFDKNARTITIDDNG
IGMSRDEAVANLGTIARSGTKEFFGKLSGDQQKDAALIGQFGVGFYSGFIVADKITVETRRAGLPAAEGVRWVSAGEGDF
SVETIERAQRGTTITLHLRADEDELLSTYKLKSIIQKYSDHVALPILMQKEEWDAEKSEMVAKDEDETVNQASALWTRAK
SDITDEQYKQFYQHLSHDHQDPLTWTHNRVEGRSEYTQLLYVPAHAPFDMWNRDHRGGLKLYVKRVFIMDDAEQLLPTYL
RFVKGVVDSADLPLNVSRELLQESRDVKAIREGVTKRALSMLEELANTEEAEGKEKYATFWKEFGQVLKEGIGEDFANKE
RIAKLARFASTHNDSSEQNVSLADYVARMKPEQSKIYYVTADTYQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLNE
FDGKPLQSVARGDLDLGQLNDEEKQAQEKVSEELKPLVERMKEALKDKAKDVRLTFRLTDSPSCLVADEGDMSGYLQRML
KAAGQNAPTFHPILEVNPEHALVKSLSTDNAHFDDWCHLLFDQALLAEGGSLEDPASFVKRTNALLLAR

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI154146191, Length=691, Percent_Identity=38.0607814761216, Blast_Score=437, Evalue=1e-122,
Organism=Homo sapiens, GI153792590, Length=690, Percent_Identity=37.9710144927536, Blast_Score=436, Evalue=1e-122,
Organism=Homo sapiens, GI20149594, Length=684, Percent_Identity=37.280701754386, Blast_Score=425, Evalue=1e-119,
Organism=Homo sapiens, GI4507677, Length=688, Percent_Identity=36.4825581395349, Blast_Score=415, Evalue=1e-116,
Organism=Homo sapiens, GI155722983, Length=637, Percent_Identity=35.9497645211931, Blast_Score=371, Evalue=1e-102,
Organism=Escherichia coli, GI1786679, Length=631, Percent_Identity=60.8557844690967, Blast_Score=794, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=673, Percent_Identity=38.1872213967311, Blast_Score=446, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17542208, Length=679, Percent_Identity=36.5243004418262, Blast_Score=395, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI115535205, Length=645, Percent_Identity=33.4883720930233, Blast_Score=317, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI115535167, Length=435, Percent_Identity=35.8620689655172, Blast_Score=255, Evalue=4e-68,
Organism=Saccharomyces cerevisiae, GI6323840, Length=682, Percent_Identity=38.41642228739, Blast_Score=452, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6325016, Length=686, Percent_Identity=37.9008746355685, Blast_Score=449, Evalue=1e-127,
Organism=Drosophila melanogaster, GI17647529, Length=685, Percent_Identity=37.8102189781022, Blast_Score=445, Evalue=1e-125,
Organism=Drosophila melanogaster, GI21357739, Length=681, Percent_Identity=36.7107195301028, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24586016, Length=646, Percent_Identity=35.7585139318885, Blast_Score=368, Evalue=1e-102,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71299; Mature: 71168

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQETMSFQAEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFEAIENSALYENDP
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
NLRIRVSFDKNARTITIDDNGIGMSRDEAVANLGTIARSGTKEFFGKLSGDQQKDAALIG
CEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHH
QFGVGFYSGFIVADKITVETRRAGLPAAEGVRWVSAGEGDFSVETIERAQRGTTITLHLR
HHHHHHHHCEEEEEEEEEEHHHCCCCHHHCCEEEECCCCCCHHHHHHHHHCCCEEEEEEE
ADEDELLSTYKLKSIIQKYSDHVALPILMQKEEWDAEKSEMVAKDEDETVNQASALWTRA
CCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHH
KSDITDEQYKQFYQHLSHDHQDPLTWTHNRVEGRSEYTQLLYVPAHAPFDMWNRDHRGGL
HCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHCCCCCCCCH
KLYVKRVFIMDDAEQLLPTYLRFVKGVVDSADLPLNVSRELLQESRDVKAIREGVTKRAL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SMLEELANTEEAEGKEKYATFWKEFGQVLKEGIGEDFANKERIAKLARFASTHNDSSEQN
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCC
VSLADYVARMKPEQSKIYYVTADTYQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLN
CHHHHHHHHCCCCCCEEEEEEECCHHHHCCCCHHHHHHHCCCEEEEEECHHHHHHHHHHH
EFDGKPLQSVARGDLDLGQLNDEEKQAQEKVSEELKPLVERMKEALKDKAKDVRLTFRLT
HHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
DSPSCLVADEGDMSGYLQRMLKAAGQNAPTFHPILEVNPEHALVKSLSTDNAHFDDWCHL
CCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHCCCCCCCHHHHHHH
LFDQALLAEGGSLEDPASFVKRTNALLLAR
HHHHHHHHCCCCCCCHHHHHHHCCCCEECC
>Mature Secondary Structure 
AQETMSFQAEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFEAIENSALYENDP
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
NLRIRVSFDKNARTITIDDNGIGMSRDEAVANLGTIARSGTKEFFGKLSGDQQKDAALIG
CEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHH
QFGVGFYSGFIVADKITVETRRAGLPAAEGVRWVSAGEGDFSVETIERAQRGTTITLHLR
HHHHHHHHCEEEEEEEEEEHHHCCCCHHHCCEEEECCCCCCHHHHHHHHHCCCEEEEEEE
ADEDELLSTYKLKSIIQKYSDHVALPILMQKEEWDAEKSEMVAKDEDETVNQASALWTRA
CCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHH
KSDITDEQYKQFYQHLSHDHQDPLTWTHNRVEGRSEYTQLLYVPAHAPFDMWNRDHRGGL
HCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHCCCCCCCCH
KLYVKRVFIMDDAEQLLPTYLRFVKGVVDSADLPLNVSRELLQESRDVKAIREGVTKRAL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SMLEELANTEEAEGKEKYATFWKEFGQVLKEGIGEDFANKERIAKLARFASTHNDSSEQN
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCC
VSLADYVARMKPEQSKIYYVTADTYQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLN
CHHHHHHHHCCCCCCEEEEEEECCHHHHCCCCHHHHHHHCCCEEEEEECHHHHHHHHHHH
EFDGKPLQSVARGDLDLGQLNDEEKQAQEKVSEELKPLVERMKEALKDKAKDVRLTFRLT
HHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
DSPSCLVADEGDMSGYLQRMLKAAGQNAPTFHPILEVNPEHALVKSLSTDNAHFDDWCHL
CCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHCCCCCCCHHHHHHH
LFDQALLAEGGSLEDPASFVKRTNALLLAR
HHHHHHHHCCCCCCCHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA