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The map label for this gene is ubiC [H]

Identifier: 186476865

GI number: 186476865

Start: 2368911

End: 2369603

Strand: Reverse

Name: ubiC [H]

Synonym: Bphy_2111

Alternate gene names: 186476865

Gene position: 2369603-2368911 (Counterclockwise)

Preceding gene: 186476867

Following gene: 186476864

Centisome position: 68.11

GC content: 68.54

Gene sequence:

>693_bases
ATGCCTATCCGTTTCGATGCTGCCGACGCGCACTGGCGCGTCGCGCCCCTTCCAGGTTTCTCGCCCGATCAGAAAGACTG
GCTCACGCGCGGCGGTTCGCTGACGGCGCATTTGCGTACGCTCGGCGCCGTCGCGGTGCGCGTGACGCGTGAGGCCGTCG
ACTTGCCGTTCAACGACGAATATGCCGCGCTCGGCAGCGCGCCGCGCACGCCCGTGTGGGTGCGCGAAGTGGTGTTGTCG
GTGGGCGGCAGGCCGTACGTCGCCGCGCACAGCATCGTGCCGCTCGCGGCAAGCACGGGCGTCTGGCAGGCGATGCGGCG
CTTGCGCACGCGGCCGCTCGCCGAACTGCTGTACAGCGATAGCAGCGTGTCGCGCTCGTCGCTAGTGAGCCGTCGCGTAA
CGGCGCGGCATCCGTTGTACGGGATCGCTTCGCGCGACATGGAGGATGCGCAGCCCCACGCACTGTTCGCGCGACGCTCG
GTGTTCGAGCGCTACGGCGAGCCGTTGATGGTGACGGAAGTCATGCTGCCCGCGTTGTGGACCCATCTCGCGACGCGCCA
TGACGAGCGTGAGCGTGTCCAGCATCCGTTGCCGCGCGATCATGGTCAGGCACTCGGTCACACGGCATCGCGCGCCGATG
TCAACGCGCGGCGCGACGCGAAGGGCACCGGCAAACAAGGAGACGCACGCTGA

Upstream 100 bases:

>100_bases
ATGCGGACATGCCTGAAACACACAGCCGACAGTTCCGCAAAAGTCCGCGGCCCATCCGCGCGAAAGGCCCGCGTTTTCCG
CGCCCCCTATAATGCGGACC

Downstream 100 bases:

>100_bases
TGCTGCGCGGCTTTCCACCCGTCGTAGCCGAGAGCACGCATACGCTGATACTCGGCAGCTTTCCCGGCGAAGCGTCGCTC
ACGGCGACGCAGTACTACGC

Product: chorismate lyase

Products: NA

Alternate protein names: CL; CPL [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MPIRFDAADAHWRVAPLPGFSPDQKDWLTRGGSLTAHLRTLGAVAVRVTREAVDLPFNDEYAALGSAPRTPVWVREVVLS
VGGRPYVAAHSIVPLAASTGVWQAMRRLRTRPLAELLYSDSSVSRSSLVSRRVTARHPLYGIASRDMEDAQPHALFARRS
VFERYGEPLMVTEVMLPALWTHLATRHDERERVQHPLPRDHGQALGHTASRADVNARRDAKGTGKQGDAR

Sequences:

>Translated_230_residues
MPIRFDAADAHWRVAPLPGFSPDQKDWLTRGGSLTAHLRTLGAVAVRVTREAVDLPFNDEYAALGSAPRTPVWVREVVLS
VGGRPYVAAHSIVPLAASTGVWQAMRRLRTRPLAELLYSDSSVSRSSLVSRRVTARHPLYGIASRDMEDAQPHALFARRS
VFERYGEPLMVTEVMLPALWTHLATRHDERERVQHPLPRDHGQALGHTASRADVNARRDAKGTGKQGDAR
>Mature_229_residues
PIRFDAADAHWRVAPLPGFSPDQKDWLTRGGSLTAHLRTLGAVAVRVTREAVDLPFNDEYAALGSAPRTPVWVREVVLSV
GGRPYVAAHSIVPLAASTGVWQAMRRLRTRPLAELLYSDSSVSRSSLVSRRVTARHPLYGIASRDMEDAQPHALFARRSV
FERYGEPLMVTEVMLPALWTHLATRHDERERVQHPLPRDHGQALGHTASRADVNARRDAKGTGKQGDAR

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway [H]

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family [H]

Homologues:

Organism=Escherichia coli, GI87082361, Length=167, Percent_Identity=26.9461077844311, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007440 [H]

Pfam domain/function: PF04345 Chor_lyase [H]

EC number: =4.1.3.40 [H]

Molecular weight: Translated: 25502; Mature: 25371

Theoretical pI: Translated: 10.97; Mature: 10.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRFDAADAHWRVAPLPGFSPDQKDWLTRGGSLTAHLRTLGAVAVRVTREAVDLPFNDE
CCCCCCCCCCCEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
YAALGSAPRTPVWVREVVLSVGGRPYVAAHSIVPLAASTGVWQAMRRLRTRPLAELLYSD
HHHCCCCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCC
SSVSRSSLVSRRVTARHPLYGIASRDMEDAQPHALFARRSVFERYGEPLMVTEVMLPALW
CCHHHHHHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
THLATRHDERERVQHPLPRDHGQALGHTASRADVNARRDAKGTGKQGDAR
HHHHHCCCHHHHHHCCCCCCHHHHHCCCCHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PIRFDAADAHWRVAPLPGFSPDQKDWLTRGGSLTAHLRTLGAVAVRVTREAVDLPFNDE
CCCCCCCCCCEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
YAALGSAPRTPVWVREVVLSVGGRPYVAAHSIVPLAASTGVWQAMRRLRTRPLAELLYSD
HHHCCCCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCC
SSVSRSSLVSRRVTARHPLYGIASRDMEDAQPHALFARRSVFERYGEPLMVTEVMLPALW
CCHHHHHHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
THLATRHDERERVQHPLPRDHGQALGHTASRADVNARRDAKGTGKQGDAR
HHHHHCCCHHHHHHCCCCCCHHHHHCCCCHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA