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The map label for this gene is yafC [C]

Identifier: 186476339

GI number: 186476339

Start: 1789969

End: 1790907

Strand: Reverse

Name: yafC [C]

Synonym: Bphy_1581

Alternate gene names: 186476339

Gene position: 1790907-1789969 (Counterclockwise)

Preceding gene: 186476344

Following gene: 186476338

Centisome position: 51.47

GC content: 64.54

Gene sequence:

>939_bases
ATGGATACGCTTCAGAACATGCGCGTATTTGTCCGCGTCGTCGAAGCGGGCAGCTTTACGGGCGCGGCGCAGCATCTCAA
TACGACGACGGCTTATGCGTCGCGCGCCGTGTCCGATCTCGAAGCGCATCTGCGCACGCGTCTCCTGAACCGCACGACGC
GCCGCATCGCGCTAACGGAAGCGGGCGAGCGCTATCTGCAGCGCTGCGAGCAGATTCTTGCGTATGTCGACCAGGCGGAA
GCCGAGGCCAGCGACGCGCATGCGCGCCCGTCGGGCAAGCTGAAAGTTCACGCGATGACGAGCTTCGGCCAGCACTACGT
GGTGCCCGCCGTGGGCCGATATCAGCAGCGTTATCCCGATGTCCATCTCGAACTGACGCTCGCGCAACGTATGCCAGACC
TGCTGGACGAAGGGTACGACGTCGCGCTCGTGCTCGCGCAGAGCCTGCCGGACTCCGGGCTGGTGTCGCAGCGTCTGGGC
AGTGCGTTCAGCATCGCGTGCGCTTCGCCCGATTATCTGGAGCGCAATGGCGTGCCGCAGACGCTGTCCGATCTGCGCGG
CCACACGTGTCTGCAGATGATCACGCCCGTGATGCCCGCCGACGAGTGGACCTTCGACGGCCCGAACGGCCAGGAAACGC
TGCATCTGGGTGCGTCGACGTTCCAGATCAACGTCGCCGAGGCGATGGCTGTGGCAGTGCGCGAAGGCATGGGGGTCGCC
GTGCTGCCTATCTATTCCGCGATTGCCGGTCTGCGTAGCGGCGAACTCGTGTGGATTCTGCCGGAGTACATCTCGCAGGA
GATGAACGTCTACGCGCTGTATCCGTCGCGGCAGTATCTGGATGCGAAGATCCGCACGTGGGTCGAGTTCCTGCGCGACG
AACTTCCCGCGACGCTCGCCACCGACCAGGCCGAACTGCGCCAGTTCGCGCGGACTTGA

Upstream 100 bases:

>100_bases
CCAGCAAGGGTGTAACGCATACTTACCGAAAATGAGATAATCGTCTTTCCAAATCGTGCAACAATCCTTCCCATACCGAA
AGATTGATTGGATGTAGATC

Downstream 100 bases:

>100_bases
AATACGTGCCCGGTGGCACGATATCCGTAAAACAGCCTTGACGGACTGTTACATCCCGCTGTCGCGCCGCAACACTTGCT
TACTTTCCTGCGGCATCGGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MDTLQNMRVFVRVVEAGSFTGAAQHLNTTTAYASRAVSDLEAHLRTRLLNRTTRRIALTEAGERYLQRCEQILAYVDQAE
AEASDAHARPSGKLKVHAMTSFGQHYVVPAVGRYQQRYPDVHLELTLAQRMPDLLDEGYDVALVLAQSLPDSGLVSQRLG
SAFSIACASPDYLERNGVPQTLSDLRGHTCLQMITPVMPADEWTFDGPNGQETLHLGASTFQINVAEAMAVAVREGMGVA
VLPIYSAIAGLRSGELVWILPEYISQEMNVYALYPSRQYLDAKIRTWVEFLRDELPATLATDQAELRQFART

Sequences:

>Translated_312_residues
MDTLQNMRVFVRVVEAGSFTGAAQHLNTTTAYASRAVSDLEAHLRTRLLNRTTRRIALTEAGERYLQRCEQILAYVDQAE
AEASDAHARPSGKLKVHAMTSFGQHYVVPAVGRYQQRYPDVHLELTLAQRMPDLLDEGYDVALVLAQSLPDSGLVSQRLG
SAFSIACASPDYLERNGVPQTLSDLRGHTCLQMITPVMPADEWTFDGPNGQETLHLGASTFQINVAEAMAVAVREGMGVA
VLPIYSAIAGLRSGELVWILPEYISQEMNVYALYPSRQYLDAKIRTWVEFLRDELPATLATDQAELRQFART
>Mature_312_residues
MDTLQNMRVFVRVVEAGSFTGAAQHLNTTTAYASRAVSDLEAHLRTRLLNRTTRRIALTEAGERYLQRCEQILAYVDQAE
AEASDAHARPSGKLKVHAMTSFGQHYVVPAVGRYQQRYPDVHLELTLAQRMPDLLDEGYDVALVLAQSLPDSGLVSQRLG
SAFSIACASPDYLERNGVPQTLSDLRGHTCLQMITPVMPADEWTFDGPNGQETLHLGASTFQINVAEAMAVAVREGMGVA
VLPIYSAIAGLRSGELVWILPEYISQEMNVYALYPSRQYLDAKIRTWVEFLRDELPATLATDQAELRQFART

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=294, Percent_Identity=34.6938775510204, Blast_Score=171, Evalue=4e-44,
Organism=Escherichia coli, GI1789639, Length=293, Percent_Identity=33.4470989761092, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=32.5259515570934, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=31.25, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI145693193, Length=293, Percent_Identity=29.3515358361775, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1787589, Length=293, Percent_Identity=26.6211604095563, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=25.6849315068493, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787879, Length=154, Percent_Identity=33.7662337662338, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788706, Length=307, Percent_Identity=23.7785016286645, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789173, Length=190, Percent_Identity=29.4736842105263, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI145693105, Length=270, Percent_Identity=24.8148148148148, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786448, Length=294, Percent_Identity=25.1700680272109, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788748, Length=123, Percent_Identity=30.8943089430894, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788481, Length=253, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI87082132, Length=303, Percent_Identity=23.1023102310231, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1787601, Length=126, Percent_Identity=25.3968253968254, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34616; Mature: 34616

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTLQNMRVFVRVVEAGSFTGAAQHLNTTTAYASRAVSDLEAHLRTRLLNRTTRRIALTE
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGERYLQRCEQILAYVDQAEAEASDAHARPSGKLKVHAMTSFGQHYVVPAVGRYQQRYPD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEECCCHHHHHHHCCC
VHLELTLAQRMPDLLDEGYDVALVLAQSLPDSGLVSQRLGSAFSIACASPDYLERNGVPQ
EEEEEEHHHHCHHHHHCCCCEEEHEEHHCCCCCHHHHHCCCCEEEEECCCHHHHHCCCCH
TLSDLRGHTCLQMITPVMPADEWTFDGPNGQETLHLGASTFQINVAEAMAVAVREGMGVA
HHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCEEEEEHHHHHHHHHHCCCCEE
VLPIYSAIAGLRSGELVWILPEYISQEMNVYALYPSRQYLDAKIRTWVEFLRDELPATLA
HHHHHHHHHCCCCCCEEEEEHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCHHC
TDQAELRQFART
CCHHHHHHHHCC
>Mature Secondary Structure
MDTLQNMRVFVRVVEAGSFTGAAQHLNTTTAYASRAVSDLEAHLRTRLLNRTTRRIALTE
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGERYLQRCEQILAYVDQAEAEASDAHARPSGKLKVHAMTSFGQHYVVPAVGRYQQRYPD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEECCCHHHHHHHCCC
VHLELTLAQRMPDLLDEGYDVALVLAQSLPDSGLVSQRLGSAFSIACASPDYLERNGVPQ
EEEEEEHHHHCHHHHHCCCCEEEHEEHHCCCCCHHHHHCCCCEEEEECCCHHHHHCCCCH
TLSDLRGHTCLQMITPVMPADEWTFDGPNGQETLHLGASTFQINVAEAMAVAVREGMGVA
HHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCEEEEEHHHHHHHHHHCCCCEE
VLPIYSAIAGLRSGELVWILPEYISQEMNVYALYPSRQYLDAKIRTWVEFLRDELPATLA
HHHHHHHHHCCCCCCEEEEEHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCHHC
TDQAELRQFART
CCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]