| Definition | Burkholderia phymatum STM815 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010622 |
| Length | 3,479,187 |
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The map label for this gene is relA [H]
Identifier: 186476317
GI number: 186476317
Start: 1766792
End: 1769032
Strand: Reverse
Name: relA [H]
Synonym: Bphy_1559
Alternate gene names: 186476317
Gene position: 1769032-1766792 (Counterclockwise)
Preceding gene: 186476318
Following gene: 186476316
Centisome position: 50.85
GC content: 64.17
Gene sequence:
>2241_bases ATGAACACCGACATCGCCACGACCGCTACCAATCCGACGCCTTCTTTCGAGGACGCGCTCGCGTTCGTGCGCGACCATGC GGGCGAGGCGCGCCTGTCGTCGGGCGAGCCGCTCGCCGAGCATGCGGCGGGCACGGCGGCCATCATGCGTACGCTCAACG TCGATCCGCCTGCGGTGCTGGCGGCAGCGCTGTTCTCGCTGACGCCGCATTTGCAGAACCCGGAGCAGACCATTGCCGAC AACTTCGGCGAGGAAGTCGCGCAACTGGTGAGCGACGTGCGCAAGCTGTTGCGGCTCGGCACCGTGAGCATGCGCGCGGC GCAGAACGCGATGCCCGAAGCAGGTCGCGACGCGCAGGCCGCGCGGCGCGTGCAGGTTGAGGCGCTGCGCAAGATGCTGC TTGCCTTTGCGCAGGACATCCGTGTGGTGCTGATCCGGCTCGCTTCACGATTGCAGTCGCTGCGCTATTACGCCGCGGCG AAGATCACGCCTTCGCCCGACGTCGCGCGCGAGACGCTGGACATTTACGCACCGCTCGCTAACCGGCTCGGTATCTGGCA ACTGAAGTGGGAACTGGAAGATCTCGCGTTCCGCTTCGAAGAGCCGCAAACCTACAAGCGCATCGCGAAGCTGCTGGACG AGAAGCGCGTCGAACGCGAGACCTATGTGGCCGAAGCAATCGCGCGGCTGCAGCGGGAGCTTGCCGCCGCGCATATCAAG GCCGAAGTGAGCGGTCGGCCCAAGCACATTTACAGCATCTGGCGGAAGATGCGCGGCAAGCAGCTCGATTTTTCCGAGCT CTACGATGTGCGTGCTTTTCGTGTCATCGTGCCGGACATCAAGGATTGCTACACGGTGCTCGGCATCGTGCATAACCTGT GGCAGCCGGTGCCGAGGGAATTCGACGACTACATCTCGCGGCCCAAGCCGAATGGCTACAAATCGCTGCACACGGTGGTG ATCGGTGACGATGGCCGTGCGTTCGAAGTGCAGATCCGCACGCAGGAGATGCATCGGTTCGCCGAATACGGCGTAGCGGC GCACTGGCGCTACAAGGAAGCGGGCACGCGCGGTTATGGCGGCCAGTTCAGTGCCAGCGAGAAGTACGACGAGAAGATCG CGTGGCTGCGTCAGCTGCTTGCATGGAAAGACGACGTATCCGAGGGCAAGCCGGGCGAACAGGGCGCGGTGAAGCCGTGG GAGCAGCTTCGCCAGGCGACGCTCGACGACGATCACATTTATACACTCACGCCGCAGGCTCGCGTGATTCCGCTGCCGCA AGGCGCGACGCCGCTCGACTTTGCGTATCACCTGCACAGCGAATTGGGGCATCGTTGCCGCGGCGCGCGGGTGGACGGCG CGATGGTGCCGCTGAACACGCCGCTGCAGAACGGGCAGACGGTCGAGATCATCGCGGTGAAAGAGGGTGGTCCGTCGCGA GACTGGCTCAACCCGCAGCTTGGCTATCTGCAAAGCCATCGCGCGCGCCAGAAGGTGCGCGCATGGTTCAACGCAGTCGA GGTGCAGGAGAACATCGCAGCGGGTCGGGCAATGGTCGAAAAGACCTTGCAGCGCGAGGGCAAGACGTCAGTCAATCTCG ATCAACTGGCCGCGAAGCTTGGGTTCAAGTCCACCGACGATCTATTTTCGGTCGTCGGCAAGGAAGAGTTCAGCCTGCGG CTGGTCGAGCAGGCGCTCAGCGACGCGCCGCCTGCCGAGCCCGCCGTTGAAGCGCCGGAGCAGTTCGAGAAGCGCAGCAG CGGTGCGAGCGTCGCGCATGGCGCGTCGACGGGTGTGCTCGTGGTCGGCGTCGATGCGTTGCTGACCCAACTGGCGCGTT GCTGCCGTCCGGCTCCGCCGGATGACATTGCGGGTTTCGTCACGCGCGGCAAGGGCATGTCGATTCATCGAAGCGATTGC CCGACGTTCCTGCGCATGGCAGAGCGCGCACCGGAGCGCGTGTTGCAAACGGCGTGGTCAGCGGACGTGATGAGCGGACG CGGCAGGTCGGTCTATCCCGTCGATCTGTCAATCGAAGCGACTGACAGGCAAGGTCTGCTGCGTGACATCTCCGAAGTCT TCGCGCGCGAGAAAATGAACGTTGTCGGCGTGAAGACGCAGTCGCGGCGCAACGCGGCGTTCATGCAGTTCACGGTGGAG GTGTCGAGTGCAGCGCAGATCCAGCGTGCGTGCGCGATGCTGGGAGAAGTGGCGGGCGTCGTAAGAGCGACGCGCAAGTG A
Upstream 100 bases:
>100_bases TGCCTCGTCGAAGTGGTGGTCGTCGCCGCCCAGCGCAGCTAATCACGAATCGCTTCAAGCATCAGACTGACCCGTCCGCG CATGCCGCGGCCGCCGCATC
Downstream 100 bases:
>100_bases ATGATGTCGCCGAATTGCGTGATGTGGGCACAAGAGAATTTTGATGTCGCTGCATAAAAACGCTTGCCAACTTTCTCCAT GCTCCATATAATCTCGTTTC
Product: (p)ppGpp synthetase I SpoT/RelA
Products: NA
Alternate protein names: (p)ppGpp synthase; ATP:GTP 3'-pyrophosphotransferase; ppGpp synthase I [H]
Number of amino acids: Translated: 746; Mature: 746
Protein sequence:
>746_residues MNTDIATTATNPTPSFEDALAFVRDHAGEARLSSGEPLAEHAAGTAAIMRTLNVDPPAVLAAALFSLTPHLQNPEQTIAD NFGEEVAQLVSDVRKLLRLGTVSMRAAQNAMPEAGRDAQAARRVQVEALRKMLLAFAQDIRVVLIRLASRLQSLRYYAAA KITPSPDVARETLDIYAPLANRLGIWQLKWELEDLAFRFEEPQTYKRIAKLLDEKRVERETYVAEAIARLQRELAAAHIK AEVSGRPKHIYSIWRKMRGKQLDFSELYDVRAFRVIVPDIKDCYTVLGIVHNLWQPVPREFDDYISRPKPNGYKSLHTVV IGDDGRAFEVQIRTQEMHRFAEYGVAAHWRYKEAGTRGYGGQFSASEKYDEKIAWLRQLLAWKDDVSEGKPGEQGAVKPW EQLRQATLDDDHIYTLTPQARVIPLPQGATPLDFAYHLHSELGHRCRGARVDGAMVPLNTPLQNGQTVEIIAVKEGGPSR DWLNPQLGYLQSHRARQKVRAWFNAVEVQENIAAGRAMVEKTLQREGKTSVNLDQLAAKLGFKSTDDLFSVVGKEEFSLR LVEQALSDAPPAEPAVEAPEQFEKRSSGASVAHGASTGVLVVGVDALLTQLARCCRPAPPDDIAGFVTRGKGMSIHRSDC PTFLRMAERAPERVLQTAWSADVMSGRGRSVYPVDLSIEATDRQGLLRDISEVFAREKMNVVGVKTQSRRNAAFMQFTVE VSSAAQIQRACAMLGEVAGVVRATRK
Sequences:
>Translated_746_residues MNTDIATTATNPTPSFEDALAFVRDHAGEARLSSGEPLAEHAAGTAAIMRTLNVDPPAVLAAALFSLTPHLQNPEQTIAD NFGEEVAQLVSDVRKLLRLGTVSMRAAQNAMPEAGRDAQAARRVQVEALRKMLLAFAQDIRVVLIRLASRLQSLRYYAAA KITPSPDVARETLDIYAPLANRLGIWQLKWELEDLAFRFEEPQTYKRIAKLLDEKRVERETYVAEAIARLQRELAAAHIK AEVSGRPKHIYSIWRKMRGKQLDFSELYDVRAFRVIVPDIKDCYTVLGIVHNLWQPVPREFDDYISRPKPNGYKSLHTVV IGDDGRAFEVQIRTQEMHRFAEYGVAAHWRYKEAGTRGYGGQFSASEKYDEKIAWLRQLLAWKDDVSEGKPGEQGAVKPW EQLRQATLDDDHIYTLTPQARVIPLPQGATPLDFAYHLHSELGHRCRGARVDGAMVPLNTPLQNGQTVEIIAVKEGGPSR DWLNPQLGYLQSHRARQKVRAWFNAVEVQENIAAGRAMVEKTLQREGKTSVNLDQLAAKLGFKSTDDLFSVVGKEEFSLR LVEQALSDAPPAEPAVEAPEQFEKRSSGASVAHGASTGVLVVGVDALLTQLARCCRPAPPDDIAGFVTRGKGMSIHRSDC PTFLRMAERAPERVLQTAWSADVMSGRGRSVYPVDLSIEATDRQGLLRDISEVFAREKMNVVGVKTQSRRNAAFMQFTVE VSSAAQIQRACAMLGEVAGVVRATRK >Mature_746_residues MNTDIATTATNPTPSFEDALAFVRDHAGEARLSSGEPLAEHAAGTAAIMRTLNVDPPAVLAAALFSLTPHLQNPEQTIAD NFGEEVAQLVSDVRKLLRLGTVSMRAAQNAMPEAGRDAQAARRVQVEALRKMLLAFAQDIRVVLIRLASRLQSLRYYAAA KITPSPDVARETLDIYAPLANRLGIWQLKWELEDLAFRFEEPQTYKRIAKLLDEKRVERETYVAEAIARLQRELAAAHIK AEVSGRPKHIYSIWRKMRGKQLDFSELYDVRAFRVIVPDIKDCYTVLGIVHNLWQPVPREFDDYISRPKPNGYKSLHTVV IGDDGRAFEVQIRTQEMHRFAEYGVAAHWRYKEAGTRGYGGQFSASEKYDEKIAWLRQLLAWKDDVSEGKPGEQGAVKPW EQLRQATLDDDHIYTLTPQARVIPLPQGATPLDFAYHLHSELGHRCRGARVDGAMVPLNTPLQNGQTVEIIAVKEGGPSR DWLNPQLGYLQSHRARQKVRAWFNAVEVQENIAAGRAMVEKTLQREGKTSVNLDQLAAKLGFKSTDDLFSVVGKEEFSLR LVEQALSDAPPAEPAVEAPEQFEKRSSGASVAHGASTGVLVVGVDALLTQLARCCRPAPPDDIAGFVTRGKGMSIHRSDC PTFLRMAERAPERVLQTAWSADVMSGRGRSVYPVDLSIEATDRQGLLRDISEVFAREKMNVVGVKTQSRRNAAFMQFTVE VSSAAQIQRACAMLGEVAGVVRATRK
Specific function: In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which i
COG id: COG0317
COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ACT domain [H]
Homologues:
Organism=Escherichia coli, GI1789147, Length=705, Percent_Identity=40.8510638297872, Blast_Score=544, Evalue=1e-156, Organism=Escherichia coli, GI1790082, Length=735, Percent_Identity=33.7414965986395, Blast_Score=387, Evalue=1e-108,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002912 - InterPro: IPR012675 - InterPro: IPR007685 - InterPro: IPR004811 - InterPro: IPR004095 - InterPro: IPR012676 [H]
Pfam domain/function: PF01842 ACT; PF04607 RelA_SpoT; PF02824 TGS [H]
EC number: =2.7.6.5 [H]
Molecular weight: Translated: 82897; Mature: 82897
Theoretical pI: Translated: 8.52; Mature: 8.52
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNTDIATTATNPTPSFEDALAFVRDHAGEARLSSGEPLAEHAAGTAAIMRTLNVDPPAVL CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHH AAALFSLTPHLQNPEQTIADNFGEEVAQLVSDVRKLLRLGTVSMRAAQNAMPEAGRDAQA HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH ARRVQVEALRKMLLAFAQDIRVVLIRLASRLQSLRYYAAAKITPSPDVARETLDIYAPLA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHH NRLGIWQLKWELEDLAFRFEEPQTYKRIAKLLDEKRVERETYVAEAIARLQRELAAAHIK HCCCEEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH AEVSGRPKHIYSIWRKMRGKQLDFSELYDVRAFRVIVPDIKDCYTVLGIVHNLWQPVPRE HHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCCCHH FDDYISRPKPNGYKSLHTVVIGDDGRAFEVQIRTQEMHRFAEYGVAAHWRYKEAGTRGYG HHHHHCCCCCCCCCCEEEEEECCCCCEEEEEEEHHHHHHHHHCCCHHEEEEHHCCCCCCC GQFSASEKYDEKIAWLRQLLAWKDDVSEGKPGEQGAVKPWEQLRQATLDDDHIYTLTPQA CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEECCCC RVIPLPQGATPLDFAYHLHSELGHRCRGARVDGAMVPLNTPLQNGQTVEIIAVKEGGPSR EEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEEEEEECCCCCC DWLNPQLGYLQSHRARQKVRAWFNAVEVQENIAAGRAMVEKTLQREGKTSVNLDQLAAKL CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH GFKSTDDLFSVVGKEEFSLRLVEQALSDAPPAEPAVEAPEQFEKRSSGASVAHGASTGVL CCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCEECCCCCCEE VVGVDALLTQLARCCRPAPPDDIAGFVTRGKGMSIHRSDCPTFLRMAERAPERVLQTAWS EEEHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHH ADVMSGRGRSVYPVDLSIEATDRQGLLRDISEVFAREKMNVVGVKTQSRRNAAFMQFTVE HHHHCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEEE VSSAAQIQRACAMLGEVAGVVRATRK HHHHHHHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure MNTDIATTATNPTPSFEDALAFVRDHAGEARLSSGEPLAEHAAGTAAIMRTLNVDPPAVL CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHH AAALFSLTPHLQNPEQTIADNFGEEVAQLVSDVRKLLRLGTVSMRAAQNAMPEAGRDAQA HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH ARRVQVEALRKMLLAFAQDIRVVLIRLASRLQSLRYYAAAKITPSPDVARETLDIYAPLA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHH NRLGIWQLKWELEDLAFRFEEPQTYKRIAKLLDEKRVERETYVAEAIARLQRELAAAHIK HCCCEEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH AEVSGRPKHIYSIWRKMRGKQLDFSELYDVRAFRVIVPDIKDCYTVLGIVHNLWQPVPRE HHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCCCHH FDDYISRPKPNGYKSLHTVVIGDDGRAFEVQIRTQEMHRFAEYGVAAHWRYKEAGTRGYG HHHHHCCCCCCCCCCEEEEEECCCCCEEEEEEEHHHHHHHHHCCCHHEEEEHHCCCCCCC GQFSASEKYDEKIAWLRQLLAWKDDVSEGKPGEQGAVKPWEQLRQATLDDDHIYTLTPQA CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEECCCC RVIPLPQGATPLDFAYHLHSELGHRCRGARVDGAMVPLNTPLQNGQTVEIIAVKEGGPSR EEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEEEEEECCCCCC DWLNPQLGYLQSHRARQKVRAWFNAVEVQENIAAGRAMVEKTLQREGKTSVNLDQLAAKL CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH GFKSTDDLFSVVGKEEFSLRLVEQALSDAPPAEPAVEAPEQFEKRSSGASVAHGASTGVL CCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCEECCCCCCEE VVGVDALLTQLARCCRPAPPDDIAGFVTRGKGMSIHRSDCPTFLRMAERAPERVLQTAWS EEEHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHH ADVMSGRGRSVYPVDLSIEATDRQGLLRDISEVFAREKMNVVGVKTQSRRNAAFMQFTVE HHHHCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEEE VSSAAQIQRACAMLGEVAGVVRATRK HHHHHHHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7928955 [H]