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The map label for this gene is lolC [H]

Identifier: 186476204

GI number: 186476204

Start: 1626650

End: 1627903

Strand: Reverse

Name: lolC [H]

Synonym: Bphy_1446

Alternate gene names: 186476204

Gene position: 1627903-1626650 (Counterclockwise)

Preceding gene: 186476210

Following gene: 186476203

Centisome position: 46.79

GC content: 63.4

Gene sequence:

>1254_bases
TTGAAACTTCCATATGAATGGCAGATCGGCTGGCGCTACACGCGCGCCGGCAAACGCACCACGGGGAACGGCTTCATCTC
GTTCATCGCGCTCGTGTCGATGTCGGGCATCGCGCTCGGCGTCGCCGCGCTAATCGTCGTGCTGTCGGTGATGAACGGTT
TCCAGAAGGAGGTGCGCGACCGCATGCTGTCGGTGCTCGCGCACGTCGAGATTTTTTCGCCGGCGGGTTCGATGCCGAAC
TGGCAGTTGACCGCGCAGGAAGCGAAGCAGAATAAGGAAGTGATCGGCGCGGCGCCGTACGTGGAAGCGCAGGCGCTGCT
GACTCGCCAGGACGCTGTGAGCGGTGTCGCGCTGCGCGGCGTCGAGCCGTCGCTCGAGCCGGAAGTGTCGGACATCGGCA
AGGAAATGAAGGCGGGCAGTCTCAACGACCTGAAGCCGGGCGAATTCGGCATCGTGCTCGGCGCGGATCTTGCCGCTGCG
CTCGGCGTCACGACGGGCGACAAGATCACGCTCGTCGCGCCCGAAGGCACGATGACGCCTGCGGGTCTGTTGCCGCGCCT
CAAGCAGTTCAACGTGGTCGGCGTCTTCGAATCCGGCCATTACGAATACGACAGCACGCTGGCGCTGATCGACATCCGCG
ACGCGCAGGCGTTGTTCCGGCTGCCCGCGCCGACTGGCGTGCGGCTGCGTCTGAAGGACATGCAGCGCGCGCCGGAAGTC
GCGCATCAGCTTGCGCGCACGCTCTCGGGAGACCTGTATATCCGCGACTGGACGCAGCAGAACAAGACGTGGTTCTCGGC
GGTGCAGATCGAGAAGCGGATGATGTTCATCATTCTCACGCTGATCATTGCGGTGGCCGCGTTCAATCTCGTTTCGTCCC
TGGTGATGACGGTGACCAACAAACAGGCCGATATCGCGATTCTGCGCACGCTCGGCGCGCAGCCCGGTTCGATCATGAAG
ATTTTCGTCGTCCAGGGCATGACGATCGGCTTCGTCGGCACAGGGATCGGCGTCGCGCTCGGCTGCCTGATCGCGTGGAG
CATTCCGTGGCTCGTGCCGATGATCGAGCATCTGCTACACGTGCAATTCCTGCCGCCGTCGGTGTACTTCATCAGCGAGC
TGCCGTCGGAACTCGTGCCCGGCGACGTGATCAAGATCGGCGTGATCGCCTTTCTGCTGTCGTGTCTCGCCACGCTCTAT
CCGAGCTGGCGCGGCGCAAAGGTGCGTCCGGCGGAGGCGCTGCGTTATGAATGA

Upstream 100 bases:

>100_bases
TCGACACGGCATTCGCGCGCCGGGCCGTCTTCGAACCACGGGCCGCGCGGATGTCCGGTAACTGCAGAACACAGCGCAAT
CACGCTGAAAAAGGACTCGC

Downstream 100 bases:

>100_bases
TCGTCCCAACAACACGTCGATGGCTTCTCAAGATTCTGCTCTGCATCCGTACGTGCTCGAAGCGACGGGCATTTCGAAGG
CGTTCGTTCAGGGCGGCCTG

Product: LolC/E family lipoprotein releasing system, transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MKLPYEWQIGWRYTRAGKRTTGNGFISFIALVSMSGIALGVAALIVVLSVMNGFQKEVRDRMLSVLAHVEIFSPAGSMPN
WQLTAQEAKQNKEVIGAAPYVEAQALLTRQDAVSGVALRGVEPSLEPEVSDIGKEMKAGSLNDLKPGEFGIVLGADLAAA
LGVTTGDKITLVAPEGTMTPAGLLPRLKQFNVVGVFESGHYEYDSTLALIDIRDAQALFRLPAPTGVRLRLKDMQRAPEV
AHQLARTLSGDLYIRDWTQQNKTWFSAVQIEKRMMFIILTLIIAVAAFNLVSSLVMTVTNKQADIAILRTLGAQPGSIMK
IFVVQGMTIGFVGTGIGVALGCLIAWSIPWLVPMIEHLLHVQFLPPSVYFISELPSELVPGDVIKIGVIAFLLSCLATLY
PSWRGAKVRPAEALRYE

Sequences:

>Translated_417_residues
MKLPYEWQIGWRYTRAGKRTTGNGFISFIALVSMSGIALGVAALIVVLSVMNGFQKEVRDRMLSVLAHVEIFSPAGSMPN
WQLTAQEAKQNKEVIGAAPYVEAQALLTRQDAVSGVALRGVEPSLEPEVSDIGKEMKAGSLNDLKPGEFGIVLGADLAAA
LGVTTGDKITLVAPEGTMTPAGLLPRLKQFNVVGVFESGHYEYDSTLALIDIRDAQALFRLPAPTGVRLRLKDMQRAPEV
AHQLARTLSGDLYIRDWTQQNKTWFSAVQIEKRMMFIILTLIIAVAAFNLVSSLVMTVTNKQADIAILRTLGAQPGSIMK
IFVVQGMTIGFVGTGIGVALGCLIAWSIPWLVPMIEHLLHVQFLPPSVYFISELPSELVPGDVIKIGVIAFLLSCLATLY
PSWRGAKVRPAEALRYE
>Mature_417_residues
MKLPYEWQIGWRYTRAGKRTTGNGFISFIALVSMSGIALGVAALIVVLSVMNGFQKEVRDRMLSVLAHVEIFSPAGSMPN
WQLTAQEAKQNKEVIGAAPYVEAQALLTRQDAVSGVALRGVEPSLEPEVSDIGKEMKAGSLNDLKPGEFGIVLGADLAAA
LGVTTGDKITLVAPEGTMTPAGLLPRLKQFNVVGVFESGHYEYDSTLALIDIRDAQALFRLPAPTGVRLRLKDMQRAPEV
AHQLARTLSGDLYIRDWTQQNKTWFSAVQIEKRMMFIILTLIIAVAAFNLVSSLVMTVTNKQADIAILRTLGAQPGSIMK
IFVVQGMTIGFVGTGIGVALGCLIAWSIPWLVPMIEHLLHVQFLPPSVYFISELPSELVPGDVIKIGVIAFLLSCLATLY
PSWRGAKVRPAEALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=416, Percent_Identity=33.6538461538462, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1787360, Length=420, Percent_Identity=36.6666666666667, Blast_Score=213, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45343; Mature: 45343

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLPYEWQIGWRYTRAGKRTTGNGFISFIALVSMSGIALGVAALIVVLSVMNGFQKEVRD
CCCCCEEECCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMLSVLAHVEIFSPAGSMPNWQLTAQEAKQNKEVIGAAPYVEAQALLTRQDAVSGVALRG
HHHHHHHHHHEECCCCCCCCCEEEHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEC
VEPSLEPEVSDIGKEMKAGSLNDLKPGEFGIVLGADLAAALGVTTGDKITLVAPEGTMTP
CCCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHCCCCCCEEEEECCCCCCCH
AGLLPRLKQFNVVGVFESGHYEYDSTLALIDIRDAQALFRLPAPTGVRLRLKDMQRAPEV
HHHHHHHHHCCEEEEEECCCEECCCEEEEEEECCCHHHHCCCCCCCCEEEHHHHHCCHHH
AHQLARTLSGDLYIRDWTQQNKTWFSAVQIEKRMMFIILTLIIAVAAFNLVSSLVMTVTN
HHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KQADIAILRTLGAQPGSIMKIFVVQGMTIGFVGTGIGVALGCLIAWSIPWLVPMIEHLLH
CCHHHHHHHHHCCCCCCEEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQFLPPSVYFISELPSELVPGDVIKIGVIAFLLSCLATLYPSWRGAKVRPAEALRYE
EECCCCCHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCC
>Mature Secondary Structure
MKLPYEWQIGWRYTRAGKRTTGNGFISFIALVSMSGIALGVAALIVVLSVMNGFQKEVRD
CCCCCEEECCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMLSVLAHVEIFSPAGSMPNWQLTAQEAKQNKEVIGAAPYVEAQALLTRQDAVSGVALRG
HHHHHHHHHHEECCCCCCCCCEEEHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEC
VEPSLEPEVSDIGKEMKAGSLNDLKPGEFGIVLGADLAAALGVTTGDKITLVAPEGTMTP
CCCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHCCCCCCEEEEECCCCCCCH
AGLLPRLKQFNVVGVFESGHYEYDSTLALIDIRDAQALFRLPAPTGVRLRLKDMQRAPEV
HHHHHHHHHCCEEEEEECCCEECCCEEEEEEECCCHHHHCCCCCCCCEEEHHHHHCCHHH
AHQLARTLSGDLYIRDWTQQNKTWFSAVQIEKRMMFIILTLIIAVAAFNLVSSLVMTVTN
HHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KQADIAILRTLGAQPGSIMKIFVVQGMTIGFVGTGIGVALGCLIAWSIPWLVPMIEHLLH
CCHHHHHHHHHCCCCCCEEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQFLPPSVYFISELPSELVPGDVIKIGVIAFLLSCLATLYPSWRGAKVRPAEALRYE
EECCCCCHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]