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The map label for this gene is hflX [H]

Identifier: 186476172

GI number: 186476172

Start: 1593234

End: 1594478

Strand: Reverse

Name: hflX [H]

Synonym: Bphy_1414

Alternate gene names: 186476172

Gene position: 1594478-1593234 (Counterclockwise)

Preceding gene: 186476173

Following gene: 186476171

Centisome position: 45.83

GC content: 62.41

Gene sequence:

>1245_bases
TTGACATCCACTAATTTGATCAACGCAGCGCTTGTCGGCATCGACTTCGGCAAGATCGATTTCGAAGCCAGTCTCGAAGA
ACTCAGCCTGCTCGCGCAAAGCGCGGGCGCCCATCCCGCCGTCACTCTCACCGGTCGCCGTTCCAGCCCCGACGCTGCGA
TGTTCGTCGGCAGCGGCAAAGCGGAAGAATTGCGCCTCGCGTGCGAAGCGAACGACGTCGACATCGTCATCTTCAATCAC
GCGCTCGCTCCCGCGCAGCAACGTAATCTGGAGCGTACGCTTAACAGACGTGTCGTCGACCGTACCAGCCTGATCCTCGA
CATCTTCGCGCAACGCGCGCGCAGCCATGAAGGCAAGCTGCAGGTGGAACTCGCGCAACTGCAATACCTCGCAACGCGAC
TCGTGCGCGCGTGGACCCACCTCGAGCGTCAAAAAGGCGGTATCGGCCTGCGCGGTCCCGGCGAAACGCAGCTTGAGACC
GACCGCCGGCTGATTGGCGAACGCATCAAGATGCTCAAGGGGCGGCTCGAAAAGCTGGGTCGCCAGCACGGCACGCAGCG
TCGCGCGCGGGCGCGCAACCGTACGATGTCGGTGTCACTCGTCGGCTATACGAACGCGGGCAAGTCGACGCTATTCAATG
CGCTGACCAAGGCACAGGCGTACGCGGCCGACCAGCTGTTCGCCACACTCGATACGACCTCGCGCCGCGTGTATCTGGGC
GAAGAGGTGGGCCAGATCGTCGTATCGGACACCGTAGGGTTCATCCGCGAGCTGCCTCACCAACTGGTGGCGGCGTTCCG
CGCGACGCTAGAAGAAACCATTCATGCCGATCTGCTGCTGCACGTCGTCGACGCATCGAGCGCGGTGCGACTAGACCAGA
TAGATCAGGTCAACGACGTGTTGCGTGAGATTGGCGCGGACGCGATCCGGCAGGTGCTCGTGTTCAACAAGATCGACGCG
GTGCCTGAGCTGGCGGCCCGAGGCGACGCGGTTGAAAGGGACGAGTATGGTAATATTTCGCGCGTCTTTTTGAGCGCGCG
CACGGGGCAAGGGCTGGACACACTGCGCGCTGCCATCGCCGAAATCGCAACGGCCGAGCAACTTCCGGAGCCTGACGGTC
TACTGTCGGAGGGAGATCCGAGAGCGGCCGTCATTCATCAAGCACAACGCGATGATGCAGGCGAAGACTACCGCGACGAC
CGCAAGATCCCAGACACGGGCGCCGACCCGTTCCAATTGCACTGA

Upstream 100 bases:

>100_bases
GCCCGTCCGGTGAATTTCCACCCGGATTCCGAATCGTCCTAACCCTTCGTCGCGGCCGGTCGAGCCTCGTCCGCAGGCGA
CACTGCCCGGCCGCTTCATT

Downstream 100 bases:

>100_bases
CCCGCTGTCTACTCTGGTGAACGAACACAGGTGAACGATTACAACGAGCGGAGTATCTGGCTGCGTGTGCGCGCCATGTT
GTCGCTGAACGACCCCCGCT

Product: GTP-binding proten HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MTSTNLINAALVGIDFGKIDFEASLEELSLLAQSAGAHPAVTLTGRRSSPDAAMFVGSGKAEELRLACEANDVDIVIFNH
ALAPAQQRNLERTLNRRVVDRTSLILDIFAQRARSHEGKLQVELAQLQYLATRLVRAWTHLERQKGGIGLRGPGETQLET
DRRLIGERIKMLKGRLEKLGRQHGTQRRARARNRTMSVSLVGYTNAGKSTLFNALTKAQAYAADQLFATLDTTSRRVYLG
EEVGQIVVSDTVGFIRELPHQLVAAFRATLEETIHADLLLHVVDASSAVRLDQIDQVNDVLREIGADAIRQVLVFNKIDA
VPELAARGDAVERDEYGNISRVFLSARTGQGLDTLRAAIAEIATAEQLPEPDGLLSEGDPRAAVIHQAQRDDAGEDYRDD
RKIPDTGADPFQLH

Sequences:

>Translated_414_residues
MTSTNLINAALVGIDFGKIDFEASLEELSLLAQSAGAHPAVTLTGRRSSPDAAMFVGSGKAEELRLACEANDVDIVIFNH
ALAPAQQRNLERTLNRRVVDRTSLILDIFAQRARSHEGKLQVELAQLQYLATRLVRAWTHLERQKGGIGLRGPGETQLET
DRRLIGERIKMLKGRLEKLGRQHGTQRRARARNRTMSVSLVGYTNAGKSTLFNALTKAQAYAADQLFATLDTTSRRVYLG
EEVGQIVVSDTVGFIRELPHQLVAAFRATLEETIHADLLLHVVDASSAVRLDQIDQVNDVLREIGADAIRQVLVFNKIDA
VPELAARGDAVERDEYGNISRVFLSARTGQGLDTLRAAIAEIATAEQLPEPDGLLSEGDPRAAVIHQAQRDDAGEDYRDD
RKIPDTGADPFQLH
>Mature_413_residues
TSTNLINAALVGIDFGKIDFEASLEELSLLAQSAGAHPAVTLTGRRSSPDAAMFVGSGKAEELRLACEANDVDIVIFNHA
LAPAQQRNLERTLNRRVVDRTSLILDIFAQRARSHEGKLQVELAQLQYLATRLVRAWTHLERQKGGIGLRGPGETQLETD
RRLIGERIKMLKGRLEKLGRQHGTQRRARARNRTMSVSLVGYTNAGKSTLFNALTKAQAYAADQLFATLDTTSRRVYLGE
EVGQIVVSDTVGFIRELPHQLVAAFRATLEETIHADLLLHVVDASSAVRLDQIDQVNDVLREIGADAIRQVLVFNKIDAV
PELAARGDAVERDEYGNISRVFLSARTGQGLDTLRAAIAEIATAEQLPEPDGLLSEGDPRAAVIHQAQRDDAGEDYRDDR
KIPDTGADPFQLH

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=232, Percent_Identity=36.2068965517241, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI310133116, Length=230, Percent_Identity=36.5217391304348, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI310124269, Length=212, Percent_Identity=37.2641509433962, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI310124267, Length=212, Percent_Identity=37.2641509433962, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI310124171, Length=212, Percent_Identity=37.2641509433962, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI310124169, Length=212, Percent_Identity=37.2641509433962, Blast_Score=109, Evalue=5e-24,
Organism=Escherichia coli, GI1790615, Length=374, Percent_Identity=54.8128342245989, Blast_Score=372, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17561038, Length=286, Percent_Identity=30.0699300699301, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24650079, Length=318, Percent_Identity=32.0754716981132, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 45459; Mature: 45328

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTNLINAALVGIDFGKIDFEASLEELSLLAQSAGAHPAVTLTGRRSSPDAAMFVGSGK
CCCCHHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECCCC
AEELRLACEANDVDIVIFNHALAPAQQRNLERTLNRRVVDRTSLILDIFAQRARSHEGKL
CHHEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
QVELAQLQYLATRLVRAWTHLERQKGGIGLRGPGETQLETDRRLIGERIKMLKGRLEKLG
EEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RQHGTQRRARARNRTMSVSLVGYTNAGKSTLFNALTKAQAYAADQLFATLDTTSRRVYLG
HHHCHHHHHHHHCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
EEVGQIVVSDTVGFIRELPHQLVAAFRATLEETIHADLLLHVVDASSAVRLDQIDQVNDV
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LREIGADAIRQVLVFNKIDAVPELAARGDAVERDEYGNISRVFLSARTGQGLDTLRAAIA
HHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHEEEECCCCCCHHHHHHHHH
EIATAEQLPEPDGLLSEGDPRAAVIHQAQRDDAGEDYRDDRKIPDTGADPFQLH
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TSTNLINAALVGIDFGKIDFEASLEELSLLAQSAGAHPAVTLTGRRSSPDAAMFVGSGK
CCCHHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECCCC
AEELRLACEANDVDIVIFNHALAPAQQRNLERTLNRRVVDRTSLILDIFAQRARSHEGKL
CHHEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
QVELAQLQYLATRLVRAWTHLERQKGGIGLRGPGETQLETDRRLIGERIKMLKGRLEKLG
EEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RQHGTQRRARARNRTMSVSLVGYTNAGKSTLFNALTKAQAYAADQLFATLDTTSRRVYLG
HHHCHHHHHHHHCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
EEVGQIVVSDTVGFIRELPHQLVAAFRATLEETIHADLLLHVVDASSAVRLDQIDQVNDV
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LREIGADAIRQVLVFNKIDAVPELAARGDAVERDEYGNISRVFLSARTGQGLDTLRAAIA
HHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHEEEECCCCCCHHHHHHHHH
EIATAEQLPEPDGLLSEGDPRAAVIHQAQRDDAGEDYRDDRKIPDTGADPFQLH
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]