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The map label for this gene is cysS [H]

Identifier: 186476148

GI number: 186476148

Start: 1562527

End: 1563924

Strand: Reverse

Name: cysS [H]

Synonym: Bphy_1390

Alternate gene names: 186476148

Gene position: 1563924-1562527 (Counterclockwise)

Preceding gene: 186476153

Following gene: 186476147

Centisome position: 44.95

GC content: 62.37

Gene sequence:

>1398_bases
ATGGAATCTCTGCGCATCTACAACACGCTCGCGCGTGACAAGCAAAATTTCGTGCCCCTTCATGAAGGCGAAGTGCGCAT
GTATGTCTGCGGGATGACGGTGTACGACTACTGTCACGTGGGCCATGCGCGGGTGATGGTCGTGTTCGACATCGTGCAGC
GCTGGCTGCGCACGCTCGGCTACAAAGTCACCTATGTGCGCAACATCACGGACATCGACGACAAGATCATTCGCCGCGCC
GTCGAGAACGGCGAGACGATCAAGTCCCTGACCGATCGCTTCATCGCGGCCCTGCATGAAGATGCCGACGCGCTCGGTAT
CGAGCGGCCCGATCTCGAGCCGCGCGCGACGGAGTTCGTGCCGCAGATGCTCGGCATGATCGAGAAGCTCGAGGCGAATG
GTTACGCGTACCAGGCTGCCGACGGCGACGTGAACTATGCCGTGCGCAAGTTCGAGAACTACGGTGCGCTGTCGGGCAAG
TCGCTCGAAGACCTGCGCGCGGGCGAGCGCGTGGCCGCCAACGACGCGAAGCAGGACCCGCTCGACTTCGTGCTGTGGAA
GCAGTCGAAGCCCGACGAGCCCGCCGACACCGGCTGGGAGTCGAAATATGGCCGCGGGCGTCCCGGCTGGCATATCGAGT
GCTCGGCGATGGGCTGCACGCTGCTCGGCGAACATTTCGACATTCATGGTGGCGGCCAGGATCTGCAGTTTCCGCACCAC
GAAAACGAAATCGCACAAAGTGAAGGCGCAACGCGCCAAACCTTCGTCAATTACTGGATGCACAACGGCTACGTCCAGAT
CGACAATGAGAAGATGTCGAAGTCGCTCGGCAACTTCTTCACGATCCGCGAGGTGCTCGCGAAGTACGATGCCGAAGTCG
TGCGGTTCTTCATTGCGCGCGCGCATTACCGTTCGCCGCTCAACTACAGCGACGTGCATCTCGACGATGCGCGCGGCGCG
CTCGCGCGTCTGTATACGGCGCTGAAGGACACGCCGCCGCAAGCGGGCGAGGTCGACTGGAACGAAGCGTACGCGCAGCG
TTTTCGCGCGGCGATGAACGACGATTTCAATACACCTGTCGCCGTGTCCGTGCTGTTCGAGCTGGTGAGCGAAGTGAACC
GTACACGCGATGCGGCGCTTGCGCGTCAATTACATGGTCTTGGGCTCGTGCTAGGGTTGCTGGGGCGCGAGCCGCGCGTC
TATCTGCAGCAGGCGGGGGCAAGCGTCGGCGAGGGCGCGTTGGATACAGCAGCGATCGAAGCGAAGATCGCCGCGCGCGT
CGCCGCGAAGCAGGCAAAGGACTACGCCGAGGCAGACCGGATCCGCAAGGAATTGCTGGACGCCGGTATCGCACTCGAAG
ACAAACCGGGCGGGTTGACCGAGTGGCGTCGCGTGTGA

Upstream 100 bases:

>100_bases
CATGCCGCCCGCCCGTGTTCGTGCATGCAGTTGCATGCTTTCGTCGGGCGCGATATGAACGAACACCAAGCGGATTTCTT
TCGGTCCACGCATCGTCTCT

Downstream 100 bases:

>100_bases
ACGCACCTCGAACTTCCCACTGATCGACTCGCCAGGCAGGAGGCAGGATGGCAACGGCCACGAAGACGCCGGCTAAACGG
GCCGCGTCTCAATCTGACGC

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MESLRIYNTLARDKQNFVPLHEGEVRMYVCGMTVYDYCHVGHARVMVVFDIVQRWLRTLGYKVTYVRNITDIDDKIIRRA
VENGETIKSLTDRFIAALHEDADALGIERPDLEPRATEFVPQMLGMIEKLEANGYAYQAADGDVNYAVRKFENYGALSGK
SLEDLRAGERVAANDAKQDPLDFVLWKQSKPDEPADTGWESKYGRGRPGWHIECSAMGCTLLGEHFDIHGGGQDLQFPHH
ENEIAQSEGATRQTFVNYWMHNGYVQIDNEKMSKSLGNFFTIREVLAKYDAEVVRFFIARAHYRSPLNYSDVHLDDARGA
LARLYTALKDTPPQAGEVDWNEAYAQRFRAAMNDDFNTPVAVSVLFELVSEVNRTRDAALARQLHGLGLVLGLLGREPRV
YLQQAGASVGEGALDTAAIEAKIAARVAAKQAKDYAEADRIRKELLDAGIALEDKPGGLTEWRRV

Sequences:

>Translated_465_residues
MESLRIYNTLARDKQNFVPLHEGEVRMYVCGMTVYDYCHVGHARVMVVFDIVQRWLRTLGYKVTYVRNITDIDDKIIRRA
VENGETIKSLTDRFIAALHEDADALGIERPDLEPRATEFVPQMLGMIEKLEANGYAYQAADGDVNYAVRKFENYGALSGK
SLEDLRAGERVAANDAKQDPLDFVLWKQSKPDEPADTGWESKYGRGRPGWHIECSAMGCTLLGEHFDIHGGGQDLQFPHH
ENEIAQSEGATRQTFVNYWMHNGYVQIDNEKMSKSLGNFFTIREVLAKYDAEVVRFFIARAHYRSPLNYSDVHLDDARGA
LARLYTALKDTPPQAGEVDWNEAYAQRFRAAMNDDFNTPVAVSVLFELVSEVNRTRDAALARQLHGLGLVLGLLGREPRV
YLQQAGASVGEGALDTAAIEAKIAARVAAKQAKDYAEADRIRKELLDAGIALEDKPGGLTEWRRV
>Mature_465_residues
MESLRIYNTLARDKQNFVPLHEGEVRMYVCGMTVYDYCHVGHARVMVVFDIVQRWLRTLGYKVTYVRNITDIDDKIIRRA
VENGETIKSLTDRFIAALHEDADALGIERPDLEPRATEFVPQMLGMIEKLEANGYAYQAADGDVNYAVRKFENYGALSGK
SLEDLRAGERVAANDAKQDPLDFVLWKQSKPDEPADTGWESKYGRGRPGWHIECSAMGCTLLGEHFDIHGGGQDLQFPHH
ENEIAQSEGATRQTFVNYWMHNGYVQIDNEKMSKSLGNFFTIREVLAKYDAEVVRFFIARAHYRSPLNYSDVHLDDARGA
LARLYTALKDTPPQAGEVDWNEAYAQRFRAAMNDDFNTPVAVSVLFELVSEVNRTRDAALARQLHGLGLVLGLLGREPRV
YLQQAGASVGEGALDTAAIEAKIAARVAAKQAKDYAEADRIRKELLDAGIALEDKPGGLTEWRRV

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=394, Percent_Identity=38.0710659898477, Blast_Score=242, Evalue=5e-64,
Organism=Homo sapiens, GI21269877, Length=263, Percent_Identity=38.7832699619772, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI303304987, Length=263, Percent_Identity=38.7832699619772, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI62240992, Length=263, Percent_Identity=38.7832699619772, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI10835051, Length=263, Percent_Identity=38.7832699619772, Blast_Score=182, Evalue=4e-46,
Organism=Escherichia coli, GI1786737, Length=467, Percent_Identity=56.1027837259101, Blast_Score=496, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17509795, Length=441, Percent_Identity=30.8390022675737, Blast_Score=168, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI17509797, Length=441, Percent_Identity=30.8390022675737, Blast_Score=168, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6324082, Length=440, Percent_Identity=31.8181818181818, Blast_Score=202, Evalue=8e-53,
Organism=Drosophila melanogaster, GI19922218, Length=391, Percent_Identity=36.5728900255754, Blast_Score=221, Evalue=6e-58,
Organism=Drosophila melanogaster, GI19922364, Length=338, Percent_Identity=34.9112426035503, Blast_Score=176, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 52262; Mature: 52262

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLRIYNTLARDKQNFVPLHEGEVRMYVCGMTVYDYCHVGHARVMVVFDIVQRWLRTLG
CCCHHHHHHHHHCHHCCCCCCCCCEEEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHHC
YKVTYVRNITDIDDKIIRRAVENGETIKSLTDRFIAALHEDADALGIERPDLEPRATEFV
CEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHH
PQMLGMIEKLEANGYAYQAADGDVNYAVRKFENYGALSGKSLEDLRAGERVAANDAKQDP
HHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHCCCCHHCCCCCCCC
LDFVLWKQSKPDEPADTGWESKYGRGRPGWHIECSAMGCTLLGEHFDIHGGGQDLQFPHH
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHCCCEEECCCCCCCCCCCC
ENEIAQSEGATRQTFVNYWMHNGYVQIDNEKMSKSLGNFFTIREVLAKYDAEVVRFFIAR
HHHHHHHCCCHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHYRSPLNYSDVHLDDARGALARLYTALKDTPPQAGEVDWNEAYAQRFRAAMNDDFNTPV
HHHCCCCCCCCEECCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHH
AVSVLFELVSEVNRTRDAALARQLHGLGLVLGLLGREPRVYLQQAGASVGEGALDTAAIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHH
AKIAARVAAKQAKDYAEADRIRKELLDAGIALEDKPGGLTEWRRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHCC
>Mature Secondary Structure
MESLRIYNTLARDKQNFVPLHEGEVRMYVCGMTVYDYCHVGHARVMVVFDIVQRWLRTLG
CCCHHHHHHHHHCHHCCCCCCCCCEEEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHHC
YKVTYVRNITDIDDKIIRRAVENGETIKSLTDRFIAALHEDADALGIERPDLEPRATEFV
CEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHH
PQMLGMIEKLEANGYAYQAADGDVNYAVRKFENYGALSGKSLEDLRAGERVAANDAKQDP
HHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHCCCCHHCCCCCCCC
LDFVLWKQSKPDEPADTGWESKYGRGRPGWHIECSAMGCTLLGEHFDIHGGGQDLQFPHH
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHCCCEEECCCCCCCCCCCC
ENEIAQSEGATRQTFVNYWMHNGYVQIDNEKMSKSLGNFFTIREVLAKYDAEVVRFFIAR
HHHHHHHCCCHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHYRSPLNYSDVHLDDARGALARLYTALKDTPPQAGEVDWNEAYAQRFRAAMNDDFNTPV
HHHCCCCCCCCEECCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHH
AVSVLFELVSEVNRTRDAALARQLHGLGLVLGLLGREPRVYLQQAGASVGEGALDTAAIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHH
AKIAARVAAKQAKDYAEADRIRKELLDAGIALEDKPGGLTEWRRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA