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The map label for this gene is yfjP [H]

Identifier: 186476147

GI number: 186476147

Start: 1561457

End: 1562479

Strand: Reverse

Name: yfjP [H]

Synonym: Bphy_1389

Alternate gene names: 186476147

Gene position: 1562479-1561457 (Counterclockwise)

Preceding gene: 186476148

Following gene: 186476146

Centisome position: 44.91

GC content: 65.59

Gene sequence:

>1023_bases
ATGGCAACGGCCACGAAGACGCCGGCTAAACGGGCCGCGTCTCAATCTGACGCGGCATCTAAAGTAAGGGCTGTGCGTGC
GCGAAGCGGCGTCAGCGCGAAGGGCGCTGCGAAGGTGGCAGTGAAATCGGCGTCTGCGAAGGGTGCCAAGGCGGGTGCGC
TGGCGAGGCCCGCGTCGGTGCGTTCTAAGGGCAACGGCGCCGAGGCGCCCGAGGCGGCGGTGAAGCCGTCGCGCGCCCGG
ACTGCGCACTTGAAAGGCAACGGCTCGCTGCCTGCCGAACTGGCGGGGGACCTGCGGGAGCTCGCACACGACGCGCAGGA
AGCGGAGCCGGTGCGCAAGCCGCGCGCGGCGGTGGCGCCTGCCGAAAGCGCGGACGCGGTGCAGGCCGCGCAGCCGTCTG
GCGTCACGCGTCCCGCGTATTGGGATAAGGCGTGCGCCGATCTCGTCAAACGCGACCGCATTCTCAAGAAGCTGATTCCG
AAATTCGGCCCGGTGCATCTATCGAGCCGCGCCGATCCGTTCGTCACGCTCGCGCGTTCGGTGATTGGTCAACAGATTTC
CGTGGCCTCTGCCCAGGCGATGTGGCAGCGTATCGTCGCGGCATGTCCGAAGCTCGCGCCGCAGCAGATCATCAAGCTCG
GTCAGGATGATCTGATGGGCTGCGGCGTGTCGAAGCGCAAGGCCGAGTACATTCTCGATCTCGCGCATCACTTCGTCTCG
GGCGCTTTACACGTCGGCAAATGGACGTCGATGGAAGACGAGGACGTGATCGCCGAGTTGACGCAGATCCGCGGCATCAG
CCGCTGGACAGCGGAGATGTTCCTGATATTCGACCTGTCGCGTCCGGACGTTCTGCCGCTCGACGATCCGAACCTGATCC
ACGCAATCAGTCAGAACTATTTCAGCGGGGAACCGGTGACACGCAGCGAGGCGCGGGAAGTCGCTGCGAACTGGGAGCCG
TGGCGCACCGTCGCGACCTGGTATATGTGGCGCAGCCTAGACCCAGCGCCTGCCGGCAACTGA

Upstream 100 bases:

>100_bases
GTATCGCACTCGAAGACAAACCGGGCGGGTTGACCGAGTGGCGTCGCGTGTGAACGCACCTCGAACTTCCCACTGATCGA
CTCGCCAGGCAGGAGGCAGG

Downstream 100 bases:

>100_bases
AGCAACAAGCGAAGCAAGAAGGGAAGCAACAAGCGAACGAATGAGCGGCACCCCTCGACGTCTATTGATTTGTTAAAATC
GATAGATTCGAGACGGTTTC

Product: HhH-GPD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MATATKTPAKRAASQSDAASKVRAVRARSGVSAKGAAKVAVKSASAKGAKAGALARPASVRSKGNGAEAPEAAVKPSRAR
TAHLKGNGSLPAELAGDLRELAHDAQEAEPVRKPRAAVAPAESADAVQAAQPSGVTRPAYWDKACADLVKRDRILKKLIP
KFGPVHLSSRADPFVTLARSVIGQQISVASAQAMWQRIVAACPKLAPQQIIKLGQDDLMGCGVSKRKAEYILDLAHHFVS
GALHVGKWTSMEDEDVIAELTQIRGISRWTAEMFLIFDLSRPDVLPLDDPNLIHAISQNYFSGEPVTRSEAREVAANWEP
WRTVATWYMWRSLDPAPAGN

Sequences:

>Translated_340_residues
MATATKTPAKRAASQSDAASKVRAVRARSGVSAKGAAKVAVKSASAKGAKAGALARPASVRSKGNGAEAPEAAVKPSRAR
TAHLKGNGSLPAELAGDLRELAHDAQEAEPVRKPRAAVAPAESADAVQAAQPSGVTRPAYWDKACADLVKRDRILKKLIP
KFGPVHLSSRADPFVTLARSVIGQQISVASAQAMWQRIVAACPKLAPQQIIKLGQDDLMGCGVSKRKAEYILDLAHHFVS
GALHVGKWTSMEDEDVIAELTQIRGISRWTAEMFLIFDLSRPDVLPLDDPNLIHAISQNYFSGEPVTRSEAREVAANWEP
WRTVATWYMWRSLDPAPAGN
>Mature_339_residues
ATATKTPAKRAASQSDAASKVRAVRARSGVSAKGAAKVAVKSASAKGAKAGALARPASVRSKGNGAEAPEAAVKPSRART
AHLKGNGSLPAELAGDLRELAHDAQEAEPVRKPRAAVAPAESADAVQAAQPSGVTRPAYWDKACADLVKRDRILKKLIPK
FGPVHLSSRADPFVTLARSVIGQQISVASAQAMWQRIVAACPKLAPQQIIKLGQDDLMGCGVSKRKAEYILDLAHHFVSG
ALHVGKWTSMEDEDVIAELTQIRGISRWTAEMFLIFDLSRPDVLPLDDPNLIHAISQNYFSGEPVTRSEAREVAANWEPW
RTVATWYMWRSLDPAPAGN

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320990, Length=202, Percent_Identity=29.2079207920792, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 36340; Mature: 36209

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: PS00037 MYB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATATKTPAKRAASQSDAASKVRAVRARSGVSAKGAAKVAVKSASAKGAKAGALARPASV
CCCCCCCHHHHHHCHHHHHHHHHHHHHHCCCCCCCCHHHHEECCCCCCCCCCCCCCCHHH
RSKGNGAEAPEAAVKPSRARTAHLKGNGSLPAELAGDLRELAHDAQEAEPVRKPRAAVAP
HCCCCCCCCCHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCC
AESADAVQAAQPSGVTRPAYWDKACADLVKRDRILKKLIPKFGPVHLSSRADPFVTLARS
CCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHH
VIGQQISVASAQAMWQRIVAACPKLAPQQIIKLGQDDLMGCGVSKRKAEYILDLAHHFVS
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHH
GALHVGKWTSMEDEDVIAELTQIRGISRWTAEMFLIFDLSRPDVLPLDDPNLIHAISQNY
HHHHCCCCCCCCHHHHHHHHHHHHCCHHHHEEEEEEEECCCCCCCCCCCCHHHHHHHHCC
FSGEPVTRSEAREVAANWEPWRTVATWYMWRSLDPAPAGN
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ATATKTPAKRAASQSDAASKVRAVRARSGVSAKGAAKVAVKSASAKGAKAGALARPASV
CCCCCCHHHHHHCHHHHHHHHHHHHHHCCCCCCCCHHHHEECCCCCCCCCCCCCCCHHH
RSKGNGAEAPEAAVKPSRARTAHLKGNGSLPAELAGDLRELAHDAQEAEPVRKPRAAVAP
HCCCCCCCCCHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCC
AESADAVQAAQPSGVTRPAYWDKACADLVKRDRILKKLIPKFGPVHLSSRADPFVTLARS
CCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHH
VIGQQISVASAQAMWQRIVAACPKLAPQQIIKLGQDDLMGCGVSKRKAEYILDLAHHFVS
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHH
GALHVGKWTSMEDEDVIAELTQIRGISRWTAEMFLIFDLSRPDVLPLDDPNLIHAISQNY
HHHHCCCCCCCCHHHHHHHHHHHHCCHHHHEEEEEEEECCCCCCCCCCCCHHHHHHHHCC
FSGEPVTRSEAREVAANWEPWRTVATWYMWRSLDPAPAGN
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]