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The map label for this gene is dapL [H]

Identifier: 186476106

GI number: 186476106

Start: 1514417

End: 1515721

Strand: Direct

Name: dapL [H]

Synonym: Bphy_1348

Alternate gene names: 186476106

Gene position: 1514417-1515721 (Clockwise)

Preceding gene: 186476102

Following gene: 186476107

Centisome position: 43.53

GC content: 66.36

Gene sequence:

>1305_bases
ATGCCAACGCATCCGGCCTTTGCGCCGATGCCGCCGCGCGCCGCCTTCACCTGCGTCAGTCACGCCGAACCACGCCCGAA
CCGCCAAGTGAACCCGCTACTCGACTCCCTTCAGCCTTATCCGTTCGAAAAACTGCGCCTGCTCTTCAAGGACGTCACGC
CGCCCGCGCATCTCTCCCATATCAGCTTCGGAATCGGCGAGCCGAAACATCCGACGCCTGAACTGATCCGCAAAGCGGTG
ATCGATTCCCTCGGCGGTCTCGCGGCCTATCCGGCGACTGTCGGCGCGCCGGCTTTGCGCGAAGCGATCGCGAAGTGGGT
CACGACGCGCTACAACCTGCCGCCCGTCGACGCTGCCACGCAGGTGTTGCCCGTGGCAGGCTCGCGCGAGGCGCTGTTCG
CGCTCGCGCAAACGGTGATCGATCCGGGGAAAAGCGCCGGCGGCGAGCCTGCGATCGTACTCTGTCCGAACCCGTTCTAT
CAAATCTACGAGGGCGCGGCGCTACTCGCGGGCGCTCAGCCGTACTTCGCCAACAGCGACCCGACGCGCAACTTCGCCTG
CGACTACTCGGCCATCCCCGACGACGTCTGGGCGCGCACCCAACTGCTGTACGTCTGCTCGCCGGGCAACCCGACGGGCG
CGGTGCTGACGCTCGACGACTGGCGTGAGCTGTTCGAACTGTCGGACCGCCACGGCTTCGTGATCGCCTCCGACGAATGC
TACTCCGAGATCTATTTCGACGAGTCGCGGCCGCCGCTCGGCGGGCTGGAAGCGGCGCACAAACTCGGCCGCGGCTTCGA
GCGGCTCGTGATGCTGTCCAGCCTGTCGAAGCGCTCCAACGTGCCGGGCATGCGCTCGGGCTTCGTCGCAGGCGATGCGT
CCATCCTCAAGCAGTTCCTGCTGTACCGCACGTATCACGGCGCGGCGCTGTCGACCGTCTATCAGACGGCCAGCATCGCC
GCCTGGAACGACGAAGCGCACGTGCGCGAAAACCGCGCGATGTACGCGCAGAAGTTTTCGACCGTGACGCCGATGCTCGC
CGGCGTGCTCCATGTCAAGCTGCCCGACGCCGCGTTCTACCTATGGGCGAACGTTGCGCGCACGGGGCTCTCGGATACCG
CGTTCGCCCAGCGGCTGTACGCCGACTATAATGTGACGGTTCTGCCCGGCTCGTATCTCGCACGCACCGCGCACGACACG
AACCCCGGCCGCGATTTTGTCCGCCTCGCGCTGGTCGCGGGCGTCGACGAATGCACGGAGGGCGTGCAGCGCATCGTCGA
ATTCTGCCGCTCGCTGGAACGCTAG

Upstream 100 bases:

>100_bases
CCGCCACCGCAAAGCCTTGTCCAATCGGACGATACGCGGTGCCGCCGCTGCCCAACACGCTATAATCGTTCACTTGTTGC
CCGTGCTATCGGTGGCGGGA

Downstream 100 bases:

>100_bases
TTCCGGCCCAGGCGCACACTTCAGGGAGCGCCGCCGCAGCGCTGCGCCCTCACCCGCTTTCCGATTCCAACTCTCTCGAA
AGATCATCACGAACATGTCG

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MPTHPAFAPMPPRAAFTCVSHAEPRPNRQVNPLLDSLQPYPFEKLRLLFKDVTPPAHLSHISFGIGEPKHPTPELIRKAV
IDSLGGLAAYPATVGAPALREAIAKWVTTRYNLPPVDAATQVLPVAGSREALFALAQTVIDPGKSAGGEPAIVLCPNPFY
QIYEGAALLAGAQPYFANSDPTRNFACDYSAIPDDVWARTQLLYVCSPGNPTGAVLTLDDWRELFELSDRHGFVIASDEC
YSEIYFDESRPPLGGLEAAHKLGRGFERLVMLSSLSKRSNVPGMRSGFVAGDASILKQFLLYRTYHGAALSTVYQTASIA
AWNDEAHVRENRAMYAQKFSTVTPMLAGVLHVKLPDAAFYLWANVARTGLSDTAFAQRLYADYNVTVLPGSYLARTAHDT
NPGRDFVRLALVAGVDECTEGVQRIVEFCRSLER

Sequences:

>Translated_434_residues
MPTHPAFAPMPPRAAFTCVSHAEPRPNRQVNPLLDSLQPYPFEKLRLLFKDVTPPAHLSHISFGIGEPKHPTPELIRKAV
IDSLGGLAAYPATVGAPALREAIAKWVTTRYNLPPVDAATQVLPVAGSREALFALAQTVIDPGKSAGGEPAIVLCPNPFY
QIYEGAALLAGAQPYFANSDPTRNFACDYSAIPDDVWARTQLLYVCSPGNPTGAVLTLDDWRELFELSDRHGFVIASDEC
YSEIYFDESRPPLGGLEAAHKLGRGFERLVMLSSLSKRSNVPGMRSGFVAGDASILKQFLLYRTYHGAALSTVYQTASIA
AWNDEAHVRENRAMYAQKFSTVTPMLAGVLHVKLPDAAFYLWANVARTGLSDTAFAQRLYADYNVTVLPGSYLARTAHDT
NPGRDFVRLALVAGVDECTEGVQRIVEFCRSLER
>Mature_433_residues
PTHPAFAPMPPRAAFTCVSHAEPRPNRQVNPLLDSLQPYPFEKLRLLFKDVTPPAHLSHISFGIGEPKHPTPELIRKAVI
DSLGGLAAYPATVGAPALREAIAKWVTTRYNLPPVDAATQVLPVAGSREALFALAQTVIDPGKSAGGEPAIVLCPNPFYQ
IYEGAALLAGAQPYFANSDPTRNFACDYSAIPDDVWARTQLLYVCSPGNPTGAVLTLDDWRELFELSDRHGFVIASDECY
SEIYFDESRPPLGGLEAAHKLGRGFERLVMLSSLSKRSNVPGMRSGFVAGDASILKQFLLYRTYHGAALSTVYQTASIAA
WNDEAHVRENRAMYAQKFSTVTPMLAGVLHVKLPDAAFYLWANVARTGLSDTAFAQRLYADYNVTVLPGSYLARTAHDTN
PGRDFVRLALVAGVDECTEGVQRIVEFCRSLER

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=259, Percent_Identity=25.0965250965251, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI169881279, Length=259, Percent_Identity=25.0965250965251, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4507369, Length=407, Percent_Identity=23.0958230958231, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI56713256, Length=260, Percent_Identity=25, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI56713254, Length=260, Percent_Identity=25, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788722, Length=421, Percent_Identity=25.8907363420428, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1786816, Length=335, Percent_Identity=25.9701492537313, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788332, Length=181, Percent_Identity=30.939226519337, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787909, Length=353, Percent_Identity=23.2294617563739, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=392, Percent_Identity=24.7448979591837, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71994472, Length=412, Percent_Identity=21.3592233009709, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71994476, Length=412, Percent_Identity=21.3592233009709, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323118, Length=246, Percent_Identity=26.4227642276423, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320317, Length=230, Percent_Identity=27.8260869565217, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI18859735, Length=373, Percent_Identity=25.4691689008043, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 47409; Mature: 47278

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTHPAFAPMPPRAAFTCVSHAEPRPNRQVNPLLDSLQPYPFEKLRLLFKDVTPPAHLSH
CCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHH
ISFGIGEPKHPTPELIRKAVIDSLGGLAAYPATVGAPALREAIAKWVTTRYNLPPVDAAT
HCCCCCCCCCCCHHHHHHHHHHHHCCCEECCHHCCCHHHHHHHHHHHHHCCCCCCCCHHH
QVLPVAGSREALFALAQTVIDPGKSAGGEPAIVLCPNPFYQIYEGAALLAGAQPYFANSD
HEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHCCCCEEECCCCCCCCCC
PTRNFACDYSAIPDDVWARTQLLYVCSPGNPTGAVLTLDDWRELFELSDRHGFVIASDEC
CCCCEECCCCCCCHHHHHCEEEEEEECCCCCCEEEEEHHHHHHHHHHCCCCCEEEECHHH
YSEIYFDESRPPLGGLEAAHKLGRGFERLVMLSSLSKRSNVPGMRSGFVAGDASILKQFL
HHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
LYRTYHGAALSTVYQTASIAAWNDEAHVRENRAMYAQKFSTVTPMLAGVLHVKLPDAAFY
HHHHHCCHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHH
LWANVARTGLSDTAFAQRLYADYNVTVLPGSYLARTAHDTNPGRDFVRLALVAGVDECTE
HHHHHHHCCCCHHHHHHHHHHCCCEEEECCHHHHHCCCCCCCCHHHHHHHHHHCHHHHHH
GVQRIVEFCRSLER
HHHHHHHHHHHHCC
>Mature Secondary Structure 
PTHPAFAPMPPRAAFTCVSHAEPRPNRQVNPLLDSLQPYPFEKLRLLFKDVTPPAHLSH
CCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHH
ISFGIGEPKHPTPELIRKAVIDSLGGLAAYPATVGAPALREAIAKWVTTRYNLPPVDAAT
HCCCCCCCCCCCHHHHHHHHHHHHCCCEECCHHCCCHHHHHHHHHHHHHCCCCCCCCHHH
QVLPVAGSREALFALAQTVIDPGKSAGGEPAIVLCPNPFYQIYEGAALLAGAQPYFANSD
HEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHCCCCEEECCCCCCCCCC
PTRNFACDYSAIPDDVWARTQLLYVCSPGNPTGAVLTLDDWRELFELSDRHGFVIASDEC
CCCCEECCCCCCCHHHHHCEEEEEEECCCCCCEEEEEHHHHHHHHHHCCCCCEEEECHHH
YSEIYFDESRPPLGGLEAAHKLGRGFERLVMLSSLSKRSNVPGMRSGFVAGDASILKQFL
HHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
LYRTYHGAALSTVYQTASIAAWNDEAHVRENRAMYAQKFSTVTPMLAGVLHVKLPDAAFY
HHHHHCCHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHH
LWANVARTGLSDTAFAQRLYADYNVTVLPGSYLARTAHDTNPGRDFVRLALVAGVDECTE
HHHHHHHCCCCHHHHHHHHHHCCCEEEECCHHHHHCCCCCCCCHHHHHHHHHHCHHHHHH
GVQRIVEFCRSLER
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA