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The map label for this gene is qseC [H]

Identifier: 186475949

GI number: 186475949

Start: 1330926

End: 1332368

Strand: Direct

Name: qseC [H]

Synonym: Bphy_1184

Alternate gene names: 186475949

Gene position: 1330926-1332368 (Clockwise)

Preceding gene: 186475948

Following gene: 186475950

Centisome position: 38.25

GC content: 68.33

Gene sequence:

>1443_bases
ATGACGCGGCCGCGCTCGACGTCCACGTCGATTCGCCGCCGGCTGATGTGGCTGATCCTCGTCAGCGTCGGCGCGGTATG
GGCGGTGATGTTCGCGTGGAGCTTCAGCAACGCGACGCGCGAGGTCGACGAATGGGACGACGCGCGCCTGATCCAGCTCG
CGCATCTGCTGATCCAGCTCGACGGTGCGAATCTCGCGAAGGTCGCGGCAGCGGGCATCGACGTGCGCAACGAATACACG
CGCGCGTCGCCCGCCGTCGACGACGACTCCGATGCGCAACCTCGCTATGCGCTTTTCGAAGTGCGCGACGCGGCGGGTCA
GGTAGTGGGCGCCAGTCCCGGCATTGCGGCGCTGCGCCACTCCGCCAGTCCCGGCGAAACGGCGGAAGGCGTGCATAGCC
TGACGGTGGACGGCCAACCGTGGCGAGCTTATGCGTTGAACGACAGCGCAACGGGCCGCAGCGTGCACGTGTTCGAACCC
GCCAATCTGCGCAGCGACCTGACGACGGGCGTCGCCAGCCGGATCGCGCGGCCGATGGCGATCGCGCTGCCTGTGCTCGC
GTTGCTGGTGTGGTTCAGCGTCGGTCACAGTTTCAGGCCGCTGTCGGCAATCTCGAAGGCCGTGCGCATGCGCGACAGCC
GTAATCTCGAGCCGATTCACGTCAACCCGTCGCCCGCCGAAGTCCGGCCGCTCGTCGACGCCATCAACCAGCTGCTCGCG
CGTCTGCAGCGTTCGATCCTGCGCGAGCGCGCCTTCACGGCCGACGCCGCGCACGAACTGAAGACGCCGCTCGCTGCGAT
CAAGGTCCAGGCACAGGTCGCGCTCGCCGCACACGACGGCGCGCAACAGCAGCAGGCGATGCAGCGCGTGGTTCAGGGCG
TCGACCGCAGCGCGCATCTGGCCGAGCAGCTGCTGCTGCTCGCCCGGCTCGACGAACGCGATACGGTGACGATCGCACGC
GTCAGGCCATATGACATCGCCGGCGAGGCGATCGCTTTCCGCGCGCCCCATGCCGAAGACAAGTCGATGAGCGTCGCGCT
CACGGGCGACGCCGACGCGGAGATCTATGGTGACCGCGTGCTGGCTCGCACGCTGATCGACAACCTGCTCGACAACGCCA
TCAAGTACGGCGACGCAGGCGGGCGCGTGCACATCAGCGTGCTGGCCGACGCGCAAACGGTCTCCATCACGGTGTCCGAC
AACGGTCCCGGTGTCTCCGACGAAGAACGCCTGCGCCTCACCGACCGCTTCTTTCGCGGCGCCTCGGCAACGGCGAGCGG
AAACGGCAGCGGCCTCGGGCTGTCGATCGTCGCGCGCATCGCCACGCATTTCAACGCGCAGATGCATATCGGCTCAGGCA
TCGGGCGGCGTGGACTCGCCGTGCAGATCGCATTTCCGCGCGTGCCGGACGCGCGCACGGCCGAGACGGCGCCCGTCTCC
TGA

Upstream 100 bases:

>100_bases
AGAGCAATGCGATCGAAGTCCATGTGTCGAACCTGCGCAAGAAGCTCGGCGGCGACGTGATCCGCACCGTGCGCGGCTTC
GGCTACGTCGTGGACAAGAC

Downstream 100 bases:

>100_bases
CGCCGCCCTGTCGGCGCATGCCCAACACTCATGTCAAGGATGACGGGCGCGAGACAACGTTGCGTCGTCCCCGTTCCGTG
CGCATGCACGGCGAAGGCCC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MTRPRSTSTSIRRRLMWLILVSVGAVWAVMFAWSFSNATREVDEWDDARLIQLAHLLIQLDGANLAKVAAAGIDVRNEYT
RASPAVDDDSDAQPRYALFEVRDAAGQVVGASPGIAALRHSASPGETAEGVHSLTVDGQPWRAYALNDSATGRSVHVFEP
ANLRSDLTTGVASRIARPMAIALPVLALLVWFSVGHSFRPLSAISKAVRMRDSRNLEPIHVNPSPAEVRPLVDAINQLLA
RLQRSILRERAFTADAAHELKTPLAAIKVQAQVALAAHDGAQQQQAMQRVVQGVDRSAHLAEQLLLLARLDERDTVTIAR
VRPYDIAGEAIAFRAPHAEDKSMSVALTGDADAEIYGDRVLARTLIDNLLDNAIKYGDAGGRVHISVLADAQTVSITVSD
NGPGVSDEERLRLTDRFFRGASATASGNGSGLGLSIVARIATHFNAQMHIGSGIGRRGLAVQIAFPRVPDARTAETAPVS

Sequences:

>Translated_480_residues
MTRPRSTSTSIRRRLMWLILVSVGAVWAVMFAWSFSNATREVDEWDDARLIQLAHLLIQLDGANLAKVAAAGIDVRNEYT
RASPAVDDDSDAQPRYALFEVRDAAGQVVGASPGIAALRHSASPGETAEGVHSLTVDGQPWRAYALNDSATGRSVHVFEP
ANLRSDLTTGVASRIARPMAIALPVLALLVWFSVGHSFRPLSAISKAVRMRDSRNLEPIHVNPSPAEVRPLVDAINQLLA
RLQRSILRERAFTADAAHELKTPLAAIKVQAQVALAAHDGAQQQQAMQRVVQGVDRSAHLAEQLLLLARLDERDTVTIAR
VRPYDIAGEAIAFRAPHAEDKSMSVALTGDADAEIYGDRVLARTLIDNLLDNAIKYGDAGGRVHISVLADAQTVSITVSD
NGPGVSDEERLRLTDRFFRGASATASGNGSGLGLSIVARIATHFNAQMHIGSGIGRRGLAVQIAFPRVPDARTAETAPVS
>Mature_479_residues
TRPRSTSTSIRRRLMWLILVSVGAVWAVMFAWSFSNATREVDEWDDARLIQLAHLLIQLDGANLAKVAAAGIDVRNEYTR
ASPAVDDDSDAQPRYALFEVRDAAGQVVGASPGIAALRHSASPGETAEGVHSLTVDGQPWRAYALNDSATGRSVHVFEPA
NLRSDLTTGVASRIARPMAIALPVLALLVWFSVGHSFRPLSAISKAVRMRDSRNLEPIHVNPSPAEVRPLVDAINQLLAR
LQRSILRERAFTADAAHELKTPLAAIKVQAQVALAAHDGAQQQQAMQRVVQGVDRSAHLAEQLLLLARLDERDTVTIARV
RPYDIAGEAIAFRAPHAEDKSMSVALTGDADAEIYGDRVLARTLIDNLLDNAIKYGDAGGRVHISVLADAQTVSITVSDN
GPGVSDEERLRLTDRFFRGASATASGNGSGLGLSIVARIATHFNAQMHIGSGIGRRGLAVQIAFPRVPDARTAETAPVS

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=455, Percent_Identity=32.5274725274725, Blast_Score=185, Evalue=6e-48,
Organism=Escherichia coli, GI1786783, Length=376, Percent_Identity=25, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1788279, Length=257, Percent_Identity=29.1828793774319, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1790551, Length=291, Percent_Identity=30.2405498281787, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788393, Length=233, Percent_Identity=31.3304721030043, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1786600, Length=209, Percent_Identity=26.7942583732057, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790346, Length=207, Percent_Identity=26.0869565217391, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790861, Length=277, Percent_Identity=26.7148014440433, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789808, Length=286, Percent_Identity=25.1748251748252, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI145693157, Length=215, Percent_Identity=27.4418604651163, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787894, Length=266, Percent_Identity=27.8195488721804, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787374, Length=327, Percent_Identity=25.6880733944954, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87082128, Length=279, Percent_Identity=25.089605734767, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786912, Length=201, Percent_Identity=27.363184079602, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51562; Mature: 51431

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPRSTSTSIRRRLMWLILVSVGAVWAVMFAWSFSNATREVDEWDDARLIQLAHLLIQL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHEE
DGANLAKVAAAGIDVRNEYTRASPAVDDDSDAQPRYALFEVRDAAGQVVGASPGIAALRH
CCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHCCCEECCCCCHHHHHC
SASPGETAEGVHSLTVDGQPWRAYALNDSATGRSVHVFEPANLRSDLTTGVASRIARPMA
CCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHCHHH
IALPVLALLVWFSVGHSFRPLSAISKAVRMRDSRNLEPIHVNPSPAEVRPLVDAINQLLA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHH
RLQRSILRERAFTADAAHELKTPLAAIKVQAQVALAAHDGAQQQQAMQRVVQGVDRSAHL
HHHHHHHHHHHHCHHHHHHHHCCHHHEEEEEEEEEEECCCHHHHHHHHHHHHHCCHHHHH
AEQLLLLARLDERDTVTIARVRPYDIAGEAIAFRAPHAEDKSMSVALTGDADAEIYGDRV
HHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHH
LARTLIDNLLDNAIKYGDAGGRVHISVLADAQTVSITVSDNGPGVSDEERLRLTDRFFRG
HHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEEEECCCCCCCCHHHHHHHHHHHCC
ASATASGNGSGLGLSIVARIATHFNAQMHIGSGIGRRGLAVQIAFPRVPDARTAETAPVS
CCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRPRSTSTSIRRRLMWLILVSVGAVWAVMFAWSFSNATREVDEWDDARLIQLAHLLIQL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHEE
DGANLAKVAAAGIDVRNEYTRASPAVDDDSDAQPRYALFEVRDAAGQVVGASPGIAALRH
CCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHCCCEECCCCCHHHHHC
SASPGETAEGVHSLTVDGQPWRAYALNDSATGRSVHVFEPANLRSDLTTGVASRIARPMA
CCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHCHHH
IALPVLALLVWFSVGHSFRPLSAISKAVRMRDSRNLEPIHVNPSPAEVRPLVDAINQLLA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHH
RLQRSILRERAFTADAAHELKTPLAAIKVQAQVALAAHDGAQQQQAMQRVVQGVDRSAHL
HHHHHHHHHHHHCHHHHHHHHCCHHHEEEEEEEEEEECCCHHHHHHHHHHHHHCCHHHHH
AEQLLLLARLDERDTVTIARVRPYDIAGEAIAFRAPHAEDKSMSVALTGDADAEIYGDRV
HHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHH
LARTLIDNLLDNAIKYGDAGGRVHISVLADAQTVSITVSDNGPGVSDEERLRLTDRFFRG
HHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEEEECCCCCCCCHHHHHHHHHHHCC
ASATASGNGSGLGLSIVARIATHFNAQMHIGSGIGRRGLAVQIAFPRVPDARTAETAPVS
CCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]