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The map label for this gene is argD [H]

Identifier: 186475936

GI number: 186475936

Start: 1315797

End: 1317080

Strand: Reverse

Name: argD [H]

Synonym: Bphy_1171

Alternate gene names: 186475936

Gene position: 1317080-1315797 (Counterclockwise)

Preceding gene: 186475937

Following gene: 186475935

Centisome position: 37.86

GC content: 65.81

Gene sequence:

>1284_bases
TTGAAATCTGAGCTCGAGTCTGGGGGCAGCGTCGAGCGCGCGGCGAACGGGGCAGCGCGCTTCGCGTCCGTCAACCCCTG
GTGGGCACAGTTTCTCGACGCAGCAGGCCTCGACATGACAGGCGCGCGTGGCGACGGCTGCTACATCGAAACGGCGGACG
GCCGCACGTTGCTCGACTGTCTCGCGGGCTTCGGCACGGCGAACCTGGGCCATGCGCATGCATCGTTGCTCGCGCGTTTC
GCCGACGCATTACAGCAGACGTCGGTGAACGTGTTTCCGTTCGAATGCGCGGAGTCGCAGCGCCTGCTCGCCGACAAACT
GATCGCTCTTTCAGGCCGGCGTTTCGGGAAAGTGTTCTTCGCGACCACGGGCGCCGAGGCCGTCGAAAGCGCCGTGAAGT
TCGCGATGACGAGCACCGGGCGGCCTGATGTCGTTGCGTTTCGCGACGCGTTCCATGGCCTGTCGATGTTTTCCTCGTTC
ATGACAGGCAATCGATTCTGGACGGAGGCGCTGCCATGGAAACCGGGCAACGTCCATCACGTCGACGCACATAATTTCGC
CGCGCTCGAAGACATGCTGGCGAGCCGCAAGGTCGCCGCCGTCGTGTTCGAGCCTGTCGCGGGTTCGTCGTCGGCGCAGC
ACTGGAACGCGCACACATCGGCGCGACTCGCCGCGCTGTGCCGCGCGACGGGAACGAAGCTGATTGCCGACGAAGTCTAT
TGCGGGCTCGGCCGCACGGGCACCTGGTTCGGCATCGACGCGATCGGCATGCGCGATGCGTCGGCGGCGCCCGACATGAT
CGTCGTCTCGAAAGGCCTGACGGGCGGGCTGGTGCCGCTGGCGGCCGTGCTGCTCGGCGACGCCGACTTCGATGCCGTGT
TCGGTGTGCCTGGCAAGGCGAAAGTGCAAGGCTCGACATTCGGCGGCAACCGGCTCGCGATGCACTGCGGTCTGATCGTG
CTCGATCTTGTCGAAAGGGAGCGGCTCGTCGGCAACGCGGCTGCGATGGGTGCGCTGATCGAGGCGCGCATCGCGGCGCG
TTTCGACGGGCGCGTGACGGTGCGTGGCAGGGGCCTTGCGCTCAGCCTCGCGCTCGACACTGAGTTCGCGCCGCCGTTCG
GCAGAAGCATGTCCGACGTATGGCTCGATCTGATGGACGGTGGCGTGCTCGCCATGCCGAATTCCGCTGCACCGGATTCG
CTGCGCCTGTCGCCGCCGCTGATTTTCGGCGTGGATGAAGTGGACTTTCTGATCGACCGACTCGACGAGGCGCTACAGCC
ATGA

Upstream 100 bases:

>100_bases
ATGCTCGAAGTGAACGTGCGGCAGCTCGAGTCGGTCGCGTTCTTCTATGGCGATCAGACGCAACTGCGGTTTCATGGATT
GCACGAAGGCAGGAGGCCGC

Downstream 100 bases:

>100_bases
ATGGAAACAATCAAAAGGAGGAGGGCGCCGGCTACGGCGCGCTGCTCCTGGCGCTATGCTGGTGGGGCCTGATGCCGCTG
TACTACTGGTATCTGAAGGA

Product: class III aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MKSELESGGSVERAANGAARFASVNPWWAQFLDAAGLDMTGARGDGCYIETADGRTLLDCLAGFGTANLGHAHASLLARF
ADALQQTSVNVFPFECAESQRLLADKLIALSGRRFGKVFFATTGAEAVESAVKFAMTSTGRPDVVAFRDAFHGLSMFSSF
MTGNRFWTEALPWKPGNVHHVDAHNFAALEDMLASRKVAAVVFEPVAGSSSAQHWNAHTSARLAALCRATGTKLIADEVY
CGLGRTGTWFGIDAIGMRDASAAPDMIVVSKGLTGGLVPLAAVLLGDADFDAVFGVPGKAKVQGSTFGGNRLAMHCGLIV
LDLVERERLVGNAAAMGALIEARIAARFDGRVTVRGRGLALSLALDTEFAPPFGRSMSDVWLDLMDGGVLAMPNSAAPDS
LRLSPPLIFGVDEVDFLIDRLDEALQP

Sequences:

>Translated_427_residues
MKSELESGGSVERAANGAARFASVNPWWAQFLDAAGLDMTGARGDGCYIETADGRTLLDCLAGFGTANLGHAHASLLARF
ADALQQTSVNVFPFECAESQRLLADKLIALSGRRFGKVFFATTGAEAVESAVKFAMTSTGRPDVVAFRDAFHGLSMFSSF
MTGNRFWTEALPWKPGNVHHVDAHNFAALEDMLASRKVAAVVFEPVAGSSSAQHWNAHTSARLAALCRATGTKLIADEVY
CGLGRTGTWFGIDAIGMRDASAAPDMIVVSKGLTGGLVPLAAVLLGDADFDAVFGVPGKAKVQGSTFGGNRLAMHCGLIV
LDLVERERLVGNAAAMGALIEARIAARFDGRVTVRGRGLALSLALDTEFAPPFGRSMSDVWLDLMDGGVLAMPNSAAPDS
LRLSPPLIFGVDEVDFLIDRLDEALQP
>Mature_427_residues
MKSELESGGSVERAANGAARFASVNPWWAQFLDAAGLDMTGARGDGCYIETADGRTLLDCLAGFGTANLGHAHASLLARF
ADALQQTSVNVFPFECAESQRLLADKLIALSGRRFGKVFFATTGAEAVESAVKFAMTSTGRPDVVAFRDAFHGLSMFSSF
MTGNRFWTEALPWKPGNVHHVDAHNFAALEDMLASRKVAAVVFEPVAGSSSAQHWNAHTSARLAALCRATGTKLIADEVY
CGLGRTGTWFGIDAIGMRDASAAPDMIVVSKGLTGGLVPLAAVLLGDADFDAVFGVPGKAKVQGSTFGGNRLAMHCGLIV
LDLVERERLVGNAAAMGALIEARIAARFDGRVTVRGRGLALSLALDTEFAPPFGRSMSDVWLDLMDGGVLAMPNSAAPDS
LRLSPPLIFGVDEVDFLIDRLDEALQP

Specific function: Unknown

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=410, Percent_Identity=28.5365853658537, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI284507298, Length=328, Percent_Identity=28.9634146341463, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI13994255, Length=420, Percent_Identity=25.7142857142857, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI37574042, Length=417, Percent_Identity=24.220623501199, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI226442705, Length=417, Percent_Identity=24.4604316546763, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI226442709, Length=391, Percent_Identity=24.0409207161125, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI24119277, Length=417, Percent_Identity=24.4604316546763, Blast_Score=86, Evalue=8e-17,
Organism=Escherichia coli, GI1787560, Length=406, Percent_Identity=31.0344827586207, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI1789016, Length=392, Percent_Identity=30.3571428571429, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI145693181, Length=388, Percent_Identity=27.5773195876289, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789759, Length=396, Percent_Identity=29.2929292929293, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788044, Length=397, Percent_Identity=27.455919395466, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786991, Length=290, Percent_Identity=28.6206896551724, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1786349, Length=313, Percent_Identity=25.5591054313099, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25144271, Length=398, Percent_Identity=29.1457286432161, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI32564660, Length=431, Percent_Identity=25.0580046403712, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI25144274, Length=249, Percent_Identity=30.9236947791165, Blast_Score=111, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6323470, Length=409, Percent_Identity=28.6063569682152, Blast_Score=132, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6324432, Length=410, Percent_Identity=25.8536585365854, Blast_Score=117, Evalue=4e-27,
Organism=Drosophila melanogaster, GI21357415, Length=399, Percent_Identity=26.8170426065163, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI161085790, Length=423, Percent_Identity=27.1867612293144, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI28574759, Length=422, Percent_Identity=27.0142180094787, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI21356575, Length=421, Percent_Identity=23.7529691211401, Blast_Score=83, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 45097; Mature: 45097

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSELESGGSVERAANGAARFASVNPWWAQFLDAAGLDMTGARGDGCYIETADGRTLLDC
CCCCCCCCCCHHHHCCCHHHCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHH
LAGFGTANLGHAHASLLARFADALQQTSVNVFPFECAESQRLLADKLIALSGRRFGKVFF
HHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEEE
ATTGAEAVESAVKFAMTSTGRPDVVAFRDAFHGLSMFSSFMTGNRFWTEALPWKPGNVHH
EECCHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEE
VDAHNFAALEDMLASRKVAAVVFEPVAGSSSAQHWNAHTSARLAALCRATGTKLIADEVY
ECCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
CGLGRTGTWFGIDAIGMRDASAAPDMIVVSKGLTGGLVPLAAVLLGDADFDAVFGVPGKA
HCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCEECCCCCC
KVQGSTFGGNRLAMHCGLIVLDLVERERLVGNAAAMGALIEARIAARFDGRVTVRGRGLA
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEE
LSLALDTEFAPPFGRSMSDVWLDLMDGGVLAMPNSAAPDSLRLSPPLIFGVDEVDFLIDR
EEEEECCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCCCEECCCCEEECCHHHHHHHHH
LDEALQP
HHHHHCC
>Mature Secondary Structure
MKSELESGGSVERAANGAARFASVNPWWAQFLDAAGLDMTGARGDGCYIETADGRTLLDC
CCCCCCCCCCHHHHCCCHHHCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHH
LAGFGTANLGHAHASLLARFADALQQTSVNVFPFECAESQRLLADKLIALSGRRFGKVFF
HHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEEE
ATTGAEAVESAVKFAMTSTGRPDVVAFRDAFHGLSMFSSFMTGNRFWTEALPWKPGNVHH
EECCHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEE
VDAHNFAALEDMLASRKVAAVVFEPVAGSSSAQHWNAHTSARLAALCRATGTKLIADEVY
ECCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
CGLGRTGTWFGIDAIGMRDASAAPDMIVVSKGLTGGLVPLAAVLLGDADFDAVFGVPGKA
HCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCEECCCCCC
KVQGSTFGGNRLAMHCGLIVLDLVERERLVGNAAAMGALIEARIAARFDGRVTVRGRGLA
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEE
LSLALDTEFAPPFGRSMSDVWLDLMDGGVLAMPNSAAPDSLRLSPPLIFGVDEVDFLIDR
EEEEECCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCCCEECCCCEEECCHHHHHHHHH
LDEALQP
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]