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The map label for this gene is nreB [H]

Identifier: 186475910

GI number: 186475910

Start: 1285407

End: 1286879

Strand: Direct

Name: nreB [H]

Synonym: Bphy_1145

Alternate gene names: 186475910

Gene position: 1285407-1286879 (Clockwise)

Preceding gene: 186475909

Following gene: 186475911

Centisome position: 36.95

GC content: 59.54

Gene sequence:

>1473_bases
ATGAATGCGCCCCCCGAAGTCCGGGTCCTGCTCGTTGAGGACAACCCGACGGACGCCCTGCTCATCGAGGAAGCACTGTC
CGATGTGCTGGAATTCCAGCACCGCCTGTTCCATACAACCCTTTTGTCCGATGCGCTCGATCGTATTCAATCGATGCAAT
TCGATATCGTGCTGCTGGATTTGGGATTGCCGGACGCACAAGGAATCGGCACGTTCAGAACCTTGCACCAGCATGCCGCC
GAACTGCCCGTCCTGGTGCTGACGGGACTTGAAGACATGTCGGTGGGGGTGAAGGCTATCCAGGAGGGTGCACAGGACTA
TCTGTCGAAGCGGGATATCAACTCATCGGAACTGGGTCGCGCCATACGCTACGCCATGGAGCGTCATCGGATTGCGATGG
CGCTCAAGGAAAGCGAGGAACGGTTTCAGCTCGCAGTCAGGGGGGCAAGCGCCGGATTGTGGGACTGGAACCCGCAGACA
GGCGCCGTTTATCTGTCGACCCAGTACAAGGAAATCATGGGGTACGAGGGGCATGAACTGCCCAACGACAGCCAGCCGAT
TCTCGACTTTATCCATCCCGACGACATCGAACGGGTCAAAACCCACCTCGCCGCGCACCTCGCGCAAAAATGCAGCTATG
AGATCGAATACCGGATACGTGTCAAGACGGGGCAGTACCGCTGGATGCACGCACGAGGCCAGGCGCTGTGGAATCAGGCC
GGCGAACCCTACCGTATGGTTGGATGGATTATCGACGTCACCGAACGTCGGCTGGCCGACGAAGCACTGCGTGAGTCGCG
CGAAGAACTGAAGCGGCTGTCGGCGAACATCCAGCGCGCCCGTGAGGAGGAAAAAGCCCGGATTGCACGTGAACTGCACG
ACGATCTCGGTCAACAACTGGCTGCCCTCAAGATCGAATGCGCGAAAAACGGCAACCGCGCCACAGATATCGATGCGCCG
AAAGCAGGCGCCGATATGAACAATATCTACGCGCTGATCGATCAACTGGTCGTCTCCGTACGACGCATAGCGACCGACCT
GCGTCCCGCCATGCTTGACGATCTTGGACTGCTGCCCGCTATCGAGTGGTTTGTCGAACGGTTCTCGTCGCGATACCCGA
TATCCGTCGTCCAGCACATCGACGCGGAGGATATCGACTTCAACCACGACAGCTCCACGGCCGTGTTCCGGATCGTCCAG
GAGGCGCTCACCAACGTGGCGCGTCATGCGGGCGCGACCCAGGTCACGCTGGAGATTTCCAGCAGCGGATCGCATTGTAT
TGTGCGGGTCGCCGACAACGGGCACGGTTGCCGGAACGATGTTCGACCGTCGCCAAGCTCATTCGGTTTAATCGGCATGC
GGGAGCGCGCCGCAGCGTTGAGCGGCGAACTGATCGTCCAGACCGCTCCCGGCCAGGGCTTCGCACTCACCGTTTTGCTG
CCACGCTTCGCGGTTGAGAACAAAAGCCCTTAG

Upstream 100 bases:

>100_bases
GCTACATAACCAAGCCCGTCGACTTCACGCGGTTCGTCGAGGTTGTACGCAGAATCAGTGACTTCTGGTTCGGCGTGGTG
ACTTTGCCCCCCGCCCGATC

Downstream 100 bases:

>100_bases
GCCACACGGGGCCGTTGCATCCATTCAAGGCCTCGGCTAATTCTTCAGCACCGGATCGCAGTCGAGCACGCTTTGCACTC
AGCGCCCCACGAAGGCGCCC

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MNAPPEVRVLLVEDNPTDALLIEEALSDVLEFQHRLFHTTLLSDALDRIQSMQFDIVLLDLGLPDAQGIGTFRTLHQHAA
ELPVLVLTGLEDMSVGVKAIQEGAQDYLSKRDINSSELGRAIRYAMERHRIAMALKESEERFQLAVRGASAGLWDWNPQT
GAVYLSTQYKEIMGYEGHELPNDSQPILDFIHPDDIERVKTHLAAHLAQKCSYEIEYRIRVKTGQYRWMHARGQALWNQA
GEPYRMVGWIIDVTERRLADEALRESREELKRLSANIQRAREEEKARIARELHDDLGQQLAALKIECAKNGNRATDIDAP
KAGADMNNIYALIDQLVVSVRRIATDLRPAMLDDLGLLPAIEWFVERFSSRYPISVVQHIDAEDIDFNHDSSTAVFRIVQ
EALTNVARHAGATQVTLEISSSGSHCIVRVADNGHGCRNDVRPSPSSFGLIGMRERAAALSGELIVQTAPGQGFALTVLL
PRFAVENKSP

Sequences:

>Translated_490_residues
MNAPPEVRVLLVEDNPTDALLIEEALSDVLEFQHRLFHTTLLSDALDRIQSMQFDIVLLDLGLPDAQGIGTFRTLHQHAA
ELPVLVLTGLEDMSVGVKAIQEGAQDYLSKRDINSSELGRAIRYAMERHRIAMALKESEERFQLAVRGASAGLWDWNPQT
GAVYLSTQYKEIMGYEGHELPNDSQPILDFIHPDDIERVKTHLAAHLAQKCSYEIEYRIRVKTGQYRWMHARGQALWNQA
GEPYRMVGWIIDVTERRLADEALRESREELKRLSANIQRAREEEKARIARELHDDLGQQLAALKIECAKNGNRATDIDAP
KAGADMNNIYALIDQLVVSVRRIATDLRPAMLDDLGLLPAIEWFVERFSSRYPISVVQHIDAEDIDFNHDSSTAVFRIVQ
EALTNVARHAGATQVTLEISSSGSHCIVRVADNGHGCRNDVRPSPSSFGLIGMRERAAALSGELIVQTAPGQGFALTVLL
PRFAVENKSP
>Mature_490_residues
MNAPPEVRVLLVEDNPTDALLIEEALSDVLEFQHRLFHTTLLSDALDRIQSMQFDIVLLDLGLPDAQGIGTFRTLHQHAA
ELPVLVLTGLEDMSVGVKAIQEGAQDYLSKRDINSSELGRAIRYAMERHRIAMALKESEERFQLAVRGASAGLWDWNPQT
GAVYLSTQYKEIMGYEGHELPNDSQPILDFIHPDDIERVKTHLAAHLAQKCSYEIEYRIRVKTGQYRWMHARGQALWNQA
GEPYRMVGWIIDVTERRLADEALRESREELKRLSANIQRAREEEKARIARELHDDLGQQLAALKIECAKNGNRATDIDAP
KAGADMNNIYALIDQLVVSVRRIATDLRPAMLDDLGLLPAIEWFVERFSSRYPISVVQHIDAEDIDFNHDSSTAVFRIVQ
EALTNVARHAGATQVTLEISSSGSHCIVRVADNGHGCRNDVRPSPSSFGLIGMRERAAALSGELIVQTAPGQGFALTVLL
PRFAVENKSP

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=200, Percent_Identity=27.5, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87082311, Length=222, Percent_Identity=31.981981981982, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54818; Mature: 54818

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPPEVRVLLVEDNPTDALLIEEALSDVLEFQHRLFHTTLLSDALDRIQSMQFDIVLLD
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEE
LGLPDAQGIGTFRTLHQHAAELPVLVLTGLEDMSVGVKAIQEGAQDYLSKRDINSSELGR
CCCCCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AIRYAMERHRIAMALKESEERFQLAVRGASAGLWDWNPQTGAVYLSTQYKEIMGYEGHEL
HHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCEEEEEEHHHHHHCCCCCCC
PNDSQPILDFIHPDDIERVKTHLAAHLAQKCSYEIEYRIRVKTGQYRWMHARGQALWNQA
CCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCEEEEHHHHHHHHHCC
GEPYRMVGWIIDVTERRLADEALRESREELKRLSANIQRAREEEKARIARELHDDLGQQL
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALKIECAKNGNRATDIDAPKAGADMNNIYALIDQLVVSVRRIATDLRPAMLDDLGLLPA
HHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
IEWFVERFSSRYPISVVQHIDAEDIDFNHDSSTAVFRIVQEALTNVARHAGATQVTLEIS
HHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
SSGSHCIVRVADNGHGCRNDVRPSPSSFGLIGMRERAAALSGELIVQTAPGQGFALTVLL
CCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEHHHHHHHCCCCEEEEECCCCCEEEEEEH
PRFAVENKSP
HHHHCCCCCC
>Mature Secondary Structure
MNAPPEVRVLLVEDNPTDALLIEEALSDVLEFQHRLFHTTLLSDALDRIQSMQFDIVLLD
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEE
LGLPDAQGIGTFRTLHQHAAELPVLVLTGLEDMSVGVKAIQEGAQDYLSKRDINSSELGR
CCCCCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AIRYAMERHRIAMALKESEERFQLAVRGASAGLWDWNPQTGAVYLSTQYKEIMGYEGHEL
HHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCEEEEEEHHHHHHCCCCCCC
PNDSQPILDFIHPDDIERVKTHLAAHLAQKCSYEIEYRIRVKTGQYRWMHARGQALWNQA
CCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCEEEEHHHHHHHHHCC
GEPYRMVGWIIDVTERRLADEALRESREELKRLSANIQRAREEEKARIARELHDDLGQQL
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALKIECAKNGNRATDIDAPKAGADMNNIYALIDQLVVSVRRIATDLRPAMLDDLGLLPA
HHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
IEWFVERFSSRYPISVVQHIDAEDIDFNHDSSTAVFRIVQEALTNVARHAGATQVTLEIS
HHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
SSGSHCIVRVADNGHGCRNDVRPSPSSFGLIGMRERAAALSGELIVQTAPGQGFALTVLL
CCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEHHHHHHHCCCCEEEEECCCCCEEEEEEH
PRFAVENKSP
HHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA