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The map label for this gene is aphA [H]

Identifier: 186475908

GI number: 186475908

Start: 1283440

End: 1284948

Strand: Direct

Name: aphA [H]

Synonym: Bphy_1143

Alternate gene names: 186475908

Gene position: 1283440-1284948 (Clockwise)

Preceding gene: 186475906

Following gene: 186475909

Centisome position: 36.89

GC content: 59.91

Gene sequence:

>1509_bases
ATGGAACCGTACAGGCAACTGAGCAGCTTGACTCACGAGCTTTTCCGCCAGGTCGTCGAAGCCGCGCCCAACGCGATGGT
GATGGCGGATCGCGAAGGTCTCGTCGTGCTCGTGAACGTGCAGGCGGAAAAGCTCTTCGGCTATCCACGCAACGAACTGG
TCGGAAATAGTGTCGATATGCTCGTCCCCGAGCGCATGCGCCGCGCGCATCCCGAGTTCCGTCGCATGTTCTACGGCGAC
CCGAGAAGCAGACCGATGGGGACGGGCCGTGATCTGTTTGCGCTACGAAAGGACGGTACCGAAGTTCCCGTCGAGATCGG
CCTGAACCCTGTTACGACGACGGAGGGCATCTTCGTACTTGCAGCTATCGTCGACATCACAGAACGCAGACGCCTGGAGG
AGCGCTTCCGGCAAGTGGTGGAAGCTGCGCCGAATGCGATGGTAATGGTCGGGCAGGACGGAAAGATCGTTCTCGTGAAT
GCGCAGACCGAGAACCTGTTCGGCTACAACCGCGAGCAGCTCTTCGGGAAGTCGATCGAAACACTCGTGCCGGAACGCTT
TCGGAGAGGTCATGAGGTTTCGCGGAACGCCTATCTACATGATCTGAAACCGCGCCCGATGGGCACGGGTCGCGATCTGT
ACGGCCGTCGCCGGGATGGCTCGGAGTTTCCCGTGGAGATCGGGCTCAACCCCGTCAGAACCTCCAATGAAAATTTCGTG
CTCGCCGCCATAGTCGACATTACGGAGCGAAAGCGCGCGGAACACGAACTCATGCGCCGGACAGAAGAGCTTGCGCGCTC
AAACCAGGATCTCGAACAGTTTGCGTACGTGGCGTCGCACGATCTACAGGAACCGCTACGCGCCGTCGCGGGGCCCCTTC
AGCTGCTTCAGCGCCGCTATCAAGGACAACTCGATGCGCGCGCGGAGGAGTTCATCACGCATGCCGTAGATGGCGCCACG
CGAATGCAAAAGCTGATCGACGACCTGCTCTCCTATTCCCGTGTCGGACGGTCGGGCGCGGTTCAGCAGTTGACTGCCTG
TGCGGCCGCACTTGATCAGGCACTGAAGAGCTTGAGCGTCGTGCTGCAGGAGTCCGGCGCGCAGATCACTCGGGATGCAC
TGCCTTGCGTCATGGCCATTCCGACGCAACTGGCGCTACTGTTTCAGAATCTGGTCGGCAATGCCGTCAAGTTTCGACAG
GTCGATCGGCCTGTGCGCGTCGACATCGGTGCGCGCCGTGAGGGCGATAGTTGGGTCATTTCGGTAAAGGACAATGGTAT
CGGCATCGACCCGCAATACTTCGACCGCATATTCATGATCTTTCAGCGCCTTCATTCCCGGGCCGATTACCCAGGAACGG
GCATCGGGCTCGCGCTATGCAAGCGTATCGTCGAGCAGCATGGAGGAAGCATCTGGATCGAGTCCCAACCGGGCGCCGGA
ACGACGGTCTTCTTTACCTTGAAGGCGGAAGATCGTGAAGCCCGTATCCCACCACAGCATACCCCGTAG

Upstream 100 bases:

>100_bases
TTTCGTATGCCCCTAAGGCTATCCATCAGCTACCGCGATCGCGGCATGAGCGCCGCCCAGGCCAGGCGTCGGCGGCGGCA
TCTTTAACGACGGGAATCGA

Downstream 100 bases:

>100_bases
GAGTAGCGCATGCCGACCCAGGCAGTTGACGATCTGATTCACATTCTTCTCGTCGAAGATAGCCCGACTGACGTCATGAT
CACGCGTGAAGCGTTCGATT

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MEPYRQLSSLTHELFRQVVEAAPNAMVMADREGLVVLVNVQAEKLFGYPRNELVGNSVDMLVPERMRRAHPEFRRMFYGD
PRSRPMGTGRDLFALRKDGTEVPVEIGLNPVTTTEGIFVLAAIVDITERRRLEERFRQVVEAAPNAMVMVGQDGKIVLVN
AQTENLFGYNREQLFGKSIETLVPERFRRGHEVSRNAYLHDLKPRPMGTGRDLYGRRRDGSEFPVEIGLNPVRTSNENFV
LAAIVDITERKRAEHELMRRTEELARSNQDLEQFAYVASHDLQEPLRAVAGPLQLLQRRYQGQLDARAEEFITHAVDGAT
RMQKLIDDLLSYSRVGRSGAVQQLTACAAALDQALKSLSVVLQESGAQITRDALPCVMAIPTQLALLFQNLVGNAVKFRQ
VDRPVRVDIGARREGDSWVISVKDNGIGIDPQYFDRIFMIFQRLHSRADYPGTGIGLALCKRIVEQHGGSIWIESQPGAG
TTVFFTLKAEDREARIPPQHTP

Sequences:

>Translated_502_residues
MEPYRQLSSLTHELFRQVVEAAPNAMVMADREGLVVLVNVQAEKLFGYPRNELVGNSVDMLVPERMRRAHPEFRRMFYGD
PRSRPMGTGRDLFALRKDGTEVPVEIGLNPVTTTEGIFVLAAIVDITERRRLEERFRQVVEAAPNAMVMVGQDGKIVLVN
AQTENLFGYNREQLFGKSIETLVPERFRRGHEVSRNAYLHDLKPRPMGTGRDLYGRRRDGSEFPVEIGLNPVRTSNENFV
LAAIVDITERKRAEHELMRRTEELARSNQDLEQFAYVASHDLQEPLRAVAGPLQLLQRRYQGQLDARAEEFITHAVDGAT
RMQKLIDDLLSYSRVGRSGAVQQLTACAAALDQALKSLSVVLQESGAQITRDALPCVMAIPTQLALLFQNLVGNAVKFRQ
VDRPVRVDIGARREGDSWVISVKDNGIGIDPQYFDRIFMIFQRLHSRADYPGTGIGLALCKRIVEQHGGSIWIESQPGAG
TTVFFTLKAEDREARIPPQHTP
>Mature_502_residues
MEPYRQLSSLTHELFRQVVEAAPNAMVMADREGLVVLVNVQAEKLFGYPRNELVGNSVDMLVPERMRRAHPEFRRMFYGD
PRSRPMGTGRDLFALRKDGTEVPVEIGLNPVTTTEGIFVLAAIVDITERRRLEERFRQVVEAAPNAMVMVGQDGKIVLVN
AQTENLFGYNREQLFGKSIETLVPERFRRGHEVSRNAYLHDLKPRPMGTGRDLYGRRRDGSEFPVEIGLNPVRTSNENFV
LAAIVDITERKRAEHELMRRTEELARSNQDLEQFAYVASHDLQEPLRAVAGPLQLLQRRYQGQLDARAEEFITHAVDGAT
RMQKLIDDLLSYSRVGRSGAVQQLTACAAALDQALKSLSVVLQESGAQITRDALPCVMAIPTQLALLFQNLVGNAVKFRQ
VDRPVRVDIGARREGDSWVISVKDNGIGIDPQYFDRIFMIFQRLHSRADYPGTGIGLALCKRIVEQHGGSIWIESQPGAG
TTVFFTLKAEDREARIPPQHTP

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=289, Percent_Identity=25.9515570934256, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI48994928, Length=392, Percent_Identity=27.8061224489796, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788549, Length=360, Percent_Identity=26.1111111111111, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87081921, Length=177, Percent_Identity=29.3785310734463, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=31.8548387096774, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789149, Length=243, Percent_Identity=25.1028806584362, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1790436, Length=249, Percent_Identity=28.5140562248996, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081816, Length=247, Percent_Identity=25.5060728744939, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790346, Length=215, Percent_Identity=27.4418604651163, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786600, Length=378, Percent_Identity=26.984126984127, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788713, Length=375, Percent_Identity=21.0666666666667, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790551, Length=238, Percent_Identity=28.1512605042017, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56507; Mature: 56507

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPYRQLSSLTHELFRQVVEAAPNAMVMADREGLVVLVNVQAEKLFGYPRNELVGNSVDM
CCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEECHHHHCCCCCHHHCCCCHHH
LVPERMRRAHPEFRRMFYGDPRSRPMGTGRDLFALRKDGTEVPVEIGLNPVTTTEGIFVL
HCHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCEEECCCCCCCCCHHHHH
AAIVDITERRRLEERFRQVVEAAPNAMVMVGQDGKIVLVNAQTENLFGYNREQLFGKSIE
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHH
TLVPERFRRGHEVSRNAYLHDLKPRPMGTGRDLYGRRRDGSEFPVEIGLNPVRTSNENFV
HHHHHHHHCCCHHCCCCCEECCCCCCCCCCCHHCCCCCCCCCCCEEECCCCCCCCCCCEE
LAAIVDITERKRAEHELMRRTEELARSNQDLEQFAYVASHDLQEPLRAVAGPLQLLQRRY
EEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGQLDARAEEFITHAVDGATRMQKLIDDLLSYSRVGRSGAVQQLTACAAALDQALKSLSV
CCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VLQESGAQITRDALPCVMAIPTQLALLFQNLVGNAVKFRQVDRPVRVDIGARREGDSWVI
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEECCCCCCCCCEEE
SVKDNGIGIDPQYFDRIFMIFQRLHSRADYPGTGIGLALCKRIVEQHGGSIWIESQPGAG
EEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCC
TTVFFTLKAEDREARIPPQHTP
EEEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MEPYRQLSSLTHELFRQVVEAAPNAMVMADREGLVVLVNVQAEKLFGYPRNELVGNSVDM
CCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEECHHHHCCCCCHHHCCCCHHH
LVPERMRRAHPEFRRMFYGDPRSRPMGTGRDLFALRKDGTEVPVEIGLNPVTTTEGIFVL
HCHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCEEECCCCCCCCCHHHHH
AAIVDITERRRLEERFRQVVEAAPNAMVMVGQDGKIVLVNAQTENLFGYNREQLFGKSIE
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHH
TLVPERFRRGHEVSRNAYLHDLKPRPMGTGRDLYGRRRDGSEFPVEIGLNPVRTSNENFV
HHHHHHHHCCCHHCCCCCEECCCCCCCCCCCHHCCCCCCCCCCCEEECCCCCCCCCCCEE
LAAIVDITERKRAEHELMRRTEELARSNQDLEQFAYVASHDLQEPLRAVAGPLQLLQRRY
EEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGQLDARAEEFITHAVDGATRMQKLIDDLLSYSRVGRSGAVQQLTACAAALDQALKSLSV
CCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VLQESGAQITRDALPCVMAIPTQLALLFQNLVGNAVKFRQVDRPVRVDIGARREGDSWVI
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEECCCCCCCCCEEE
SVKDNGIGIDPQYFDRIFMIFQRLHSRADYPGTGIGLALCKRIVEQHGGSIWIESQPGAG
EEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCC
TTVFFTLKAEDREARIPPQHTP
EEEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]