| Definition | Burkholderia phymatum STM815 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010622 |
| Length | 3,479,187 |
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The map label for this gene is phbB [H]
Identifier: 186475736
GI number: 186475736
Start: 1085656
End: 1086396
Strand: Direct
Name: phbB [H]
Synonym: Bphy_0971
Alternate gene names: 186475736
Gene position: 1085656-1086396 (Clockwise)
Preceding gene: 186475735
Following gene: 186475737
Centisome position: 31.2
GC content: 60.05
Gene sequence:
>741_bases ATGTCACAACGAATTGCGTACGTAACAGGCGGCATGGGTGGCATCGGCACGAGCATTTGCCAGCGTCTGCATAAAGATGG CTTCAAGGTGATCGCGGGCTGCGGCCCCAACTCGCCGCGCCGCGTGAAGTGGCTCGAAGATCAGAAGGCGCTTGGCTTCG ACTTTGTTGCTTCCGAAGGCAACGTGGGCGACTGGGAGTCGACCAAGGCCGCGTTCGACAAGGTGAAAGCAGAAGTCGGC GAAATCGATGTGCTGGTGAACAATGCGGGCATCACGCGCGACGTCGTGTTCCGCAAGATGACGCATGAAGACTGGACGGC CGTGATCGACACGAACCTGACCAGCCTCTTCAACGTGACGAAGCAGGTGATCGACGGCATGGTCGAGCGTGGCTGGGGCC GCGTGATCAACATTTCGTCGGTAAATGGCCAGAAAGGTCAGTTCGGTCAAACGAACTACTCGACCGCGAAGGCGGGCATT CACGGTTTCACGATGGCGCTCGCGCAGGAAGTGGCCACCAAGGGCGTGACGGTCAACACCGTTTCGCCGGGCTACATCGG CACGGACATGGTGAAATCGATTCGCGCCGACGTGCTGGAAAAAATCGTCGCGACGATTCCGGTGCGCCGTCTCGGCACGC CGGATGAAATCGGGTCGATCGTCGCATGGCTGGCATCGGACGAGTCGGGCTTCTCGACGGGGGCTGACTTCTCTCTGAAC GGCGGCCTGCATATGGGCTGA
Upstream 100 bases:
>100_bases GTGCGCGTCGCGTGAGCGAGCGAGCGGCCTGCATCCGGGACCTTGGAAGGCGAAGCACGAGGCGGCTGGCGTCTCGTAAA ACGATAATGGAGTGTGTTTT
Downstream 100 bases:
>100_bases TCCGTGAGCGTCCTATCTTGTCGCAGCATGGGCAAAGCAGGACGTTGCATGGTTCAGATGTTTCTGGCGGCGTCTTGCAC GCGCAGCGTCAAGCTGTGCG
Product: acetyacetyl-CoA reductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 246; Mature: 245
Protein sequence:
>246_residues MSQRIAYVTGGMGGIGTSICQRLHKDGFKVIAGCGPNSPRRVKWLEDQKALGFDFVASEGNVGDWESTKAAFDKVKAEVG EIDVLVNNAGITRDVVFRKMTHEDWTAVIDTNLTSLFNVTKQVIDGMVERGWGRVINISSVNGQKGQFGQTNYSTAKAGI HGFTMALAQEVATKGVTVNTVSPGYIGTDMVKSIRADVLEKIVATIPVRRLGTPDEIGSIVAWLASDESGFSTGADFSLN GGLHMG
Sequences:
>Translated_246_residues MSQRIAYVTGGMGGIGTSICQRLHKDGFKVIAGCGPNSPRRVKWLEDQKALGFDFVASEGNVGDWESTKAAFDKVKAEVG EIDVLVNNAGITRDVVFRKMTHEDWTAVIDTNLTSLFNVTKQVIDGMVERGWGRVINISSVNGQKGQFGQTNYSTAKAGI HGFTMALAQEVATKGVTVNTVSPGYIGTDMVKSIRADVLEKIVATIPVRRLGTPDEIGSIVAWLASDESGFSTGADFSLN GGLHMG >Mature_245_residues SQRIAYVTGGMGGIGTSICQRLHKDGFKVIAGCGPNSPRRVKWLEDQKALGFDFVASEGNVGDWESTKAAFDKVKAEVGE IDVLVNNAGITRDVVFRKMTHEDWTAVIDTNLTSLFNVTKQVIDGMVERGWGRVINISSVNGQKGQFGQTNYSTAKAGIH GFTMALAQEVATKGVTVNTVSPGYIGTDMVKSIRADVLEKIVATIPVRRLGTPDEIGSIVAWLASDESGFSTGADFSLNG GLHMG
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=34.7826086956522, Blast_Score=144, Evalue=8e-35, Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=33.4677419354839, Blast_Score=131, Evalue=6e-31, Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=32.2834645669291, Blast_Score=108, Evalue=6e-24, Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=29.1497975708502, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI4504505, Length=249, Percent_Identity=31.3253012048193, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=27.8225806451613, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=28.4, Blast_Score=91, Evalue=7e-19, Organism=Homo sapiens, GI83715985, Length=254, Percent_Identity=30.7086614173228, Blast_Score=91, Evalue=8e-19, Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=27.5303643724696, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=28, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI66933014, Length=187, Percent_Identity=29.4117647058824, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=27.6422764227642, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI109715829, Length=239, Percent_Identity=24.6861924686192, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI59889578, Length=175, Percent_Identity=32.5714285714286, Blast_Score=81, Evalue=9e-16, Organism=Homo sapiens, GI7705855, Length=209, Percent_Identity=30.622009569378, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI150247226, Length=191, Percent_Identity=30.8900523560209, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=30.5825242718447, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI7706318, Length=202, Percent_Identity=27.2277227722772, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI40548397, Length=207, Percent_Identity=30.4347826086957, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI214010158, Length=207, Percent_Identity=30.4347826086957, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI214010156, Length=207, Percent_Identity=30.4347826086957, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI22758144, Length=207, Percent_Identity=30.4347826086957, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI33667109, Length=198, Percent_Identity=30.8080808080808, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI22507405, Length=187, Percent_Identity=30.4812834224599, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI19743808, Length=193, Percent_Identity=29.5336787564767, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI7657478, Length=200, Percent_Identity=26.5, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI20149619, Length=200, Percent_Identity=26, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI44680136, Length=187, Percent_Identity=31.0160427807487, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI44680133, Length=187, Percent_Identity=31.0160427807487, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI17738292, Length=187, Percent_Identity=31.0160427807487, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI4503817, Length=185, Percent_Identity=27.5675675675676, Blast_Score=65, Evalue=4e-11, Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=42.3387096774194, Blast_Score=198, Evalue=3e-52, Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=36.6533864541833, Blast_Score=146, Evalue=1e-36, Organism=Escherichia coli, GI1790717, Length=240, Percent_Identity=32.9166666666667, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=29.7520661157025, Blast_Score=115, Evalue=2e-27, Organism=Escherichia coli, GI1788459, Length=254, Percent_Identity=28.3464566929134, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=32, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=26.9387755102041, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1787820, Length=193, Percent_Identity=33.160621761658, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=29.7520661157025, Blast_Score=87, Evalue=9e-19, Organism=Escherichia coli, GI1786812, Length=204, Percent_Identity=26.4705882352941, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=26.6666666666667, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=26.5873015873016, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=24.6153846153846, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1786701, Length=187, Percent_Identity=26.7379679144385, Blast_Score=64, Evalue=1e-11, Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=39.2712550607287, Blast_Score=158, Evalue=2e-39, Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=36.5853658536585, Blast_Score=155, Evalue=2e-38, Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=30.4, Blast_Score=111, Evalue=4e-25, Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=33.8582677165354, Blast_Score=110, Evalue=9e-25, Organism=Caenorhabditis elegans, GI17568967, Length=247, Percent_Identity=32.3886639676113, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=29.5546558704453, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=29.2, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=28, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI115534694, Length=239, Percent_Identity=28.0334728033473, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI193203115, Length=152, Percent_Identity=32.8947368421053, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI193203117, Length=152, Percent_Identity=32.8947368421053, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=28.968253968254, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=28.7878787878788, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=28.6852589641434, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17561272, Length=196, Percent_Identity=28.0612244897959, Blast_Score=78, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=26.8, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=27.2388059701493, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17538486, Length=247, Percent_Identity=26.3157894736842, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=26.5151515151515, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=28.3524904214559, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=27.843137254902, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17507613, Length=212, Percent_Identity=25.4716981132075, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI32563809, Length=212, Percent_Identity=25, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI193204405, Length=248, Percent_Identity=27.8225806451613, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17562990, Length=185, Percent_Identity=29.7297297297297, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=27.3764258555133, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=25.7462686567164, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=24.907063197026, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=248, Percent_Identity=31.4516129032258, Blast_Score=105, Evalue=6e-24, Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=26.2745098039216, Blast_Score=77, Evalue=2e-15, Organism=Saccharomyces cerevisiae, GI6323882, Length=201, Percent_Identity=26.3681592039801, Blast_Score=68, Evalue=1e-12, Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=34.5381526104418, Blast_Score=137, Evalue=5e-33, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=33.8645418326693, Blast_Score=117, Evalue=8e-27, Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=30.5555555555556, Blast_Score=107, Evalue=7e-24, Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=32.4, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI21357041, Length=174, Percent_Identity=37.3563218390805, Blast_Score=105, Evalue=2e-23, Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=31.496062992126, Blast_Score=100, Evalue=8e-22, Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=26.8, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=27.9352226720648, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI18859837, Length=232, Percent_Identity=30.6034482758621, Blast_Score=88, Evalue=5e-18, Organism=Drosophila melanogaster, GI24644337, Length=169, Percent_Identity=32.5443786982249, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=29.5918367346939, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI24641232, Length=216, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI116007236, Length=203, Percent_Identity=29.5566502463054, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI24581726, Length=177, Percent_Identity=24.8587570621469, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24648693, Length=204, Percent_Identity=30.3921568627451, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI21355889, Length=204, Percent_Identity=30.3921568627451, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24641388, Length=205, Percent_Identity=30.7317073170732, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011283 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.36 [H]
Molecular weight: Translated: 26301; Mature: 26170
Theoretical pI: Translated: 6.95; Mature: 6.95
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSQRIAYVTGGMGGIGTSICQRLHKDGFKVIAGCGPNSPRRVKWLEDQKALGFDFVASEG CCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCCCCEEEEECCC NVGDWESTKAAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTHEDWTAVIDTNLTSLFNVT CCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCHHEEECCCHHHHHHHH KQVIDGMVERGWGRVINISSVNGQKGQFGQTNYSTAKAGIHGFTMALAQEVATKGVTVNT HHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEC VSPGYIGTDMVKSIRADVLEKIVATIPVRRLGTPDEIGSIVAWLASDESGFSTGADFSLN CCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEC GGLHMG CCCCCC >Mature Secondary Structure SQRIAYVTGGMGGIGTSICQRLHKDGFKVIAGCGPNSPRRVKWLEDQKALGFDFVASEG CCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCCCCEEEEECCC NVGDWESTKAAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTHEDWTAVIDTNLTSLFNVT CCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCHHEEECCCHHHHHHHH KQVIDGMVERGWGRVINISSVNGQKGQFGQTNYSTAKAGIHGFTMALAQEVATKGVTVNT HHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEC VSPGYIGTDMVKSIRADVLEKIVATIPVRRLGTPDEIGSIVAWLASDESGFSTGADFSLN CCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEC GGLHMG CCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2670935 [H]