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The map label for this gene is dnaX [H]

Identifier: 186475716

GI number: 186475716

Start: 1062461

End: 1064842

Strand: Direct

Name: dnaX [H]

Synonym: Bphy_0951

Alternate gene names: 186475716

Gene position: 1062461-1064842 (Clockwise)

Preceding gene: 186475709

Following gene: 186475717

Centisome position: 30.54

GC content: 67.84

Gene sequence:

>2382_bases
ATGACCTATCAAGTTCTCGCACGCAAATGGCGGCCGAAGGATTTCGCGTCGCTCGTCGGACAGGAGCACGTGGTGCGCGC
GCTCACGCACGCGCTCGATGGTGGCCGTTTGCACCACGCCTATCTGTTTACCGGCACGCGCGGCGTCGGCAAGACGACGC
TGTCGCGGATCTTCGCGAAGGCGCTCAACTGCGAAACGGGCGTCACGTCCACGCCTTGCGGTGTCTGCCGTGCGTGTCGC
GAGATCGATGAAGGGCGCTTCGTCGATTACGTCGAAATGGACGCGGCGAGCAATCGCGGCGTCGACGAAATGGCCGCGCT
GCTGGAGCGCGCCGTGTACGCGCCCGTCGATGCGCGCTTCAAGGTCTACATGATCGACGAAGTGCACATGCTGACGAACC
ACGCGTTCAACGCGATGTTGAAGACGCTGGAAGAGCCGCCGCCGCACGTCAAGTTCATCCTGGCCACGACCGATCCGCAG
AAGATCCCCGTCACGGTGCTCTCGCGCTGTCTTCAGTTCAATCTCAAGCAGATGCCGGCGGGGCACATCGTGTCGCATCT
TGAGCGCATTCTCGGCGAAGAAAACATTGCGCATGAAGCGCAAGCGCTGCGCCTGCTCGCGCGCGCCGCTGACGGCTCCA
TGCGCGATGCGCTGTCGCTCACCGATCAGGCGATCGCTTACTCGGCGAACCAGGTGACGGAGGAAGCCGTGCGCGGCATG
CTCGGCGCGCTCGATCAAAGCTATCTGATCCGCTTGCTCGATGCGCTGGTAGCGGGCGGCGGCGCGGCGGTGCTGTCGGT
CGCCGACGAGATGGCCTTGCGCAGCCTGTCGTTCTCCACCGCGCTGCAGGATCTGGCCAGCCTGTTGCACAAGATCGCAT
GGGCGCAATTCGCGCCGTCGTCGGTGCTCGAAGAATGGCCGGAAGCGGCCGATCTGCGCCGCTTTGCGGACGCGCTGAGT
CCCGAGCAGGTGCAATTGTTCTATCAGATCGCGACGATCGGCCGAAGCGAACTGGGTCTCGCGCCCGACGAATATGCTGG
CTTCACGATGACGCTGCTGCGCATGCTCGCATTCGAGCCGGCGTCGAATGGCGGCGGGGGCAGCGGAGGCGGCGTGGCAC
CCGCAGGACGTACTTCGGTGCCCGCCGCAGGCGCGAAGCGCACGGGGGCGCCCGTCGCGGCGGCTCCGCAAGCTCGTGCA
ACGGGAGCGGCAGCGCCGTCTGCCGCGAGCGGCGAGCCGGGCGTGGCGCCGATCGTGAAGGCCGAACCGGCGCCAGTTCA
ACCACCGGTTGTTCAGCAGGTGCCAGCGACAGCGGCGTCGACGGATCTCGTTGCACCGGAAATCGAAGCAGCCCCCGTCG
ACGGCGATGCAACACCGCTTTCAGCGTCGGCAGCACAAGCGGCCGCGAGTGTCGAAACGCCCGTCGCGTCGAACGGGACC
GAACAGAACGCCGCGCCGCATGACGGTATGCCTGCACTGGCCGCAGCCGCACCGCGCCGCGCAGGCGGCGCCAGCGCTGC
GCTCGACGTATTGCGTAACGCGGGCATGAAGGTATCGACGGATCGCGGCCGGTCGGCGGTTTCCACATCCGCAGCCGCAG
CGGCGCCCGCAACGCCCGTCAAGGCCGCTGCACCGCGCGTCGCCGTGCGGGTGCCGACGCCCGATCCCGCGCGCCGTGCC
GCGGCCGCTGCGCAGCAGGAAAGCGCCGCGCGCGCGCCGACGCCTCGCGCCGCAGAGCCGCAGGGCGCGTCGGCTGTTCC
GCCGTGGGAAGACATTCCGCCCGACGACTACATGCCCGCTTCGTCCGACGACGCATTCTTCGCACCGCCCGACGACAACT
TCGTGCCCGTCTTCGACAGCGGTCCGGACGACATGCTCGTCGGCCGGGGCCATGCGTCCGCGGCAGCGTCCGCTCCCGCG
GCACCCGTCATCGATATTCGAACGCTGCCGCCCGCCGTGCCGCTTCATGCAATCGGCTTCGACGGCGACTGGCCTGCGCT
CGCCGTCACGCTGCCGCTCAAGGGTATCTCGTATCAGCTCGCCTTCAACAGCGAGCTGATGGCCGTCAACGGCAAGACGC
TGAAGCTCAACGTCGCGGTCCAGCTGTACGCCGAGCCCGCGCAGATCGCAAAGCTCAAGGCGGCGCTCGCGGAACGTCTG
GGGAGCGAGATTGACGTGCAGGTCGAAGTCGGCCCCGTGCAGCGCACGGCTGCCGTGCTCGATTCGATCGAGCGCGCCAA
ACGTCAACAGGAAGCCGAACGCGAGATCGGCGCCGATCCGTTCGTGCAGTCCCTGATCCGCGAGTTCGGCGCGAGCATCG
TGCCGGGCTCCGTTCGTCCGCTGATGCCGGGCGCCGAAGGCGGCCAGAGCGCGGCCCACTGA

Upstream 100 bases:

>100_bases
CCTTAGCGAAATTCAATGATCCGTCAAAGCGTTGTCACGCCTCGTGCGAGCGCGCAATCGTTTCGTCTTTTCGCGTCAGC
GTTGCTGATACAATTTCCAG

Downstream 100 bases:

>100_bases
TTTCCGCGCGAGGCCGCATCGCCAACGCACAACGTGCACGCGCCTAACCGAATCCATTATCACGAAGGAGCAAGTCCATG
ATGAAAGGCCAACTCGCCGG

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 793; Mature: 792

Protein sequence:

>793_residues
MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSTPCGVCRACR
EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ
KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEENIAHEAQALRLLARAADGSMRDALSLTDQAIAYSANQVTEEAVRGM
LGALDQSYLIRLLDALVAGGGAAVLSVADEMALRSLSFSTALQDLASLLHKIAWAQFAPSSVLEEWPEAADLRRFADALS
PEQVQLFYQIATIGRSELGLAPDEYAGFTMTLLRMLAFEPASNGGGGSGGGVAPAGRTSVPAAGAKRTGAPVAAAPQARA
TGAAAPSAASGEPGVAPIVKAEPAPVQPPVVQQVPATAASTDLVAPEIEAAPVDGDATPLSASAAQAAASVETPVASNGT
EQNAAPHDGMPALAAAAPRRAGGASAALDVLRNAGMKVSTDRGRSAVSTSAAAAAPATPVKAAAPRVAVRVPTPDPARRA
AAAAQQESAARAPTPRAAEPQGASAVPPWEDIPPDDYMPASSDDAFFAPPDDNFVPVFDSGPDDMLVGRGHASAAASAPA
APVIDIRTLPPAVPLHAIGFDGDWPALAVTLPLKGISYQLAFNSELMAVNGKTLKLNVAVQLYAEPAQIAKLKAALAERL
GSEIDVQVEVGPVQRTAAVLDSIERAKRQQEAEREIGADPFVQSLIREFGASIVPGSVRPLMPGAEGGQSAAH

Sequences:

>Translated_793_residues
MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSTPCGVCRACR
EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ
KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEENIAHEAQALRLLARAADGSMRDALSLTDQAIAYSANQVTEEAVRGM
LGALDQSYLIRLLDALVAGGGAAVLSVADEMALRSLSFSTALQDLASLLHKIAWAQFAPSSVLEEWPEAADLRRFADALS
PEQVQLFYQIATIGRSELGLAPDEYAGFTMTLLRMLAFEPASNGGGGSGGGVAPAGRTSVPAAGAKRTGAPVAAAPQARA
TGAAAPSAASGEPGVAPIVKAEPAPVQPPVVQQVPATAASTDLVAPEIEAAPVDGDATPLSASAAQAAASVETPVASNGT
EQNAAPHDGMPALAAAAPRRAGGASAALDVLRNAGMKVSTDRGRSAVSTSAAAAAPATPVKAAAPRVAVRVPTPDPARRA
AAAAQQESAARAPTPRAAEPQGASAVPPWEDIPPDDYMPASSDDAFFAPPDDNFVPVFDSGPDDMLVGRGHASAAASAPA
APVIDIRTLPPAVPLHAIGFDGDWPALAVTLPLKGISYQLAFNSELMAVNGKTLKLNVAVQLYAEPAQIAKLKAALAERL
GSEIDVQVEVGPVQRTAAVLDSIERAKRQQEAEREIGADPFVQSLIREFGASIVPGSVRPLMPGAEGGQSAAH
>Mature_792_residues
TYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSTPCGVCRACRE
IDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQK
IPVTVLSRCLQFNLKQMPAGHIVSHLERILGEENIAHEAQALRLLARAADGSMRDALSLTDQAIAYSANQVTEEAVRGML
GALDQSYLIRLLDALVAGGGAAVLSVADEMALRSLSFSTALQDLASLLHKIAWAQFAPSSVLEEWPEAADLRRFADALSP
EQVQLFYQIATIGRSELGLAPDEYAGFTMTLLRMLAFEPASNGGGGSGGGVAPAGRTSVPAAGAKRTGAPVAAAPQARAT
GAAAPSAASGEPGVAPIVKAEPAPVQPPVVQQVPATAASTDLVAPEIEAAPVDGDATPLSASAAQAAASVETPVASNGTE
QNAAPHDGMPALAAAAPRRAGGASAALDVLRNAGMKVSTDRGRSAVSTSAAAAAPATPVKAAAPRVAVRVPTPDPARRAA
AAAQQESAARAPTPRAAEPQGASAVPPWEDIPPDDYMPASSDDAFFAPPDDNFVPVFDSGPDDMLVGRGHASAAASAPAA
PVIDIRTLPPAVPLHAIGFDGDWPALAVTLPLKGISYQLAFNSELMAVNGKTLKLNVAVQLYAEPAQIAKLKAALAERLG
SEIDVQVEVGPVQRTAAVLDSIERAKRQQEAEREIGADPFVQSLIREFGASIVPGSVRPLMPGAEGGQSAAH

Specific function: The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=322, Percent_Identity=23.9130434782609, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI194306571, Length=325, Percent_Identity=23.6923076923077, Blast_Score=77, Evalue=7e-14,
Organism=Homo sapiens, GI194306567, Length=325, Percent_Identity=23.6923076923077, Blast_Score=77, Evalue=7e-14,
Organism=Homo sapiens, GI194306569, Length=245, Percent_Identity=24.8979591836735, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1786676, Length=361, Percent_Identity=56.786703601108, Blast_Score=431, Evalue=1e-122,
Organism=Escherichia coli, GI1787341, Length=183, Percent_Identity=31.1475409836066, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1787119, Length=230, Percent_Identity=27.8260869565217, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324039, Length=245, Percent_Identity=25.3061224489796, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI18859927, Length=295, Percent_Identity=21.6949152542373, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19921076, Length=304, Percent_Identity=23.6842105263158, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022001
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12168 DNA_pol3_tau_4; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 82472; Mature: 82341

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAK
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHH
ALNCETGVTSTPCGVCRACREIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARF
HHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCE
KVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQMPA
EEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCH
GHIVSHLERILGEENIAHEAQALRLLARAADGSMRDALSLTDQAIAYSANQVTEEAVRGM
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGALDQSYLIRLLDALVAGGGAAVLSVADEMALRSLSFSTALQDLASLLHKIAWAQFAPS
HHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SVLEEWPEAADLRRFADALSPEQVQLFYQIATIGRSELGLAPDEYAGFTMTLLRMLAFEP
HHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHCCCCCHHHCCHHHHHHHHHHCCC
ASNGGGGSGGGVAPAGRTSVPAAGAKRTGAPVAAAPQARATGAAAPSAASGEPGVAPIVK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
AEPAPVQPPVVQQVPATAASTDLVAPEIEAAPVDGDATPLSASAAQAAASVETPVASNGT
CCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
EQNAAPHDGMPALAAAAPRRAGGASAALDVLRNAGMKVSTDRGRSAVSTSAAAAAPATPV
CCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCEEECCCCCHHHHHHHHHCCCCCCC
KAAAPRVAVRVPTPDPARRAAAAAQQESAARAPTPRAAEPQGASAVPPWEDIPPDDYMPA
HHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SSDDAFFAPPDDNFVPVFDSGPDDMLVGRGHASAAASAPAAPVIDIRTLPPAVPLHAIGF
CCCCCEECCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCEEEEECCCCCCCEEEECC
DGDWPALAVTLPLKGISYQLAFNSELMAVNGKTLKLNVAVQLYAEPAQIAKLKAALAERL
CCCCCEEEEEEECCCCEEEEEECCEEEEECCCEEEEEEEEEEECCHHHHHHHHHHHHHHC
GSEIDVQVEVGPVQRTAAVLDSIERAKRQQEAEREIGADPFVQSLIREFGASIVPGSVRP
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCC
LMPGAEGGQSAAH
CCCCCCCCCCCCC
>Mature Secondary Structure 
TYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAK
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHH
ALNCETGVTSTPCGVCRACREIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARF
HHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCE
KVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQMPA
EEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCH
GHIVSHLERILGEENIAHEAQALRLLARAADGSMRDALSLTDQAIAYSANQVTEEAVRGM
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGALDQSYLIRLLDALVAGGGAAVLSVADEMALRSLSFSTALQDLASLLHKIAWAQFAPS
HHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SVLEEWPEAADLRRFADALSPEQVQLFYQIATIGRSELGLAPDEYAGFTMTLLRMLAFEP
HHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHCCCCCHHHCCHHHHHHHHHHCCC
ASNGGGGSGGGVAPAGRTSVPAAGAKRTGAPVAAAPQARATGAAAPSAASGEPGVAPIVK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
AEPAPVQPPVVQQVPATAASTDLVAPEIEAAPVDGDATPLSASAAQAAASVETPVASNGT
CCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
EQNAAPHDGMPALAAAAPRRAGGASAALDVLRNAGMKVSTDRGRSAVSTSAAAAAPATPV
CCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCEEECCCCCHHHHHHHHHCCCCCCC
KAAAPRVAVRVPTPDPARRAAAAAQQESAARAPTPRAAEPQGASAVPPWEDIPPDDYMPA
HHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SSDDAFFAPPDDNFVPVFDSGPDDMLVGRGHASAAASAPAAPVIDIRTLPPAVPLHAIGF
CCCCCEECCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCEEEEECCCCCCCEEEECC
DGDWPALAVTLPLKGISYQLAFNSELMAVNGKTLKLNVAVQLYAEPAQIAKLKAALAERL
CCCCCEEEEEEECCCCEEEEEECCEEEEECCCEEEEEEEEEEECCHHHHHHHHHHHHHHC
GSEIDVQVEVGPVQRTAAVLDSIERAKRQQEAEREIGADPFVQSLIREFGASIVPGSVRP
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCC
LMPGAEGGQSAAH
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534795; 3018672; 9278503; 2186364; 2187190; 2181440; 1575709 [H]