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The map label for this gene is moaE [H]

Identifier: 186475700

GI number: 186475700

Start: 1039068

End: 1039544

Strand: Direct

Name: moaE [H]

Synonym: Bphy_0935

Alternate gene names: 186475700

Gene position: 1039068-1039544 (Clockwise)

Preceding gene: 186475699

Following gene: 186475702

Centisome position: 29.87

GC content: 61.01

Gene sequence:

>477_bases
ATGACCGTGCGCGTTCAGACTGAAGATTTCGACCTGTCGACGGAAGTGGCCGCGTTGCGCGCACAGAATCCGAAGGTGGG
CGCCGTTGCGTGCTTCGTCGGCACGGTGCGCGACATCAACGAAGGCGAAACCGTCGAGACGATGGAACTCGAGCATTACC
CCGGCATGACCGAGAAATCGCTGGAAGCGATCGTCGATGCGGCGCGCGAGCGCTGGCCCGGCACTGAGGTGCTGATCGTG
CATCGGGTCGGCAAGCTGCAGCCGCTGGACCAGATCGTGCTAGTTGCGACGACGTCGAAACATCGCGGGAATGCGTTTGC
GTCGTGCGAATTCGTGATGGACTACCTGAAAACCCAAGCGCCGTTCTGGAAGAAAGAGAAAACCGAAAGCGGCGAACGCT
GGGTCGACGCGCGCGTGGCGGACGAGCAGGCACTGGCACGCTGGGGACTTGAATCCCTGAATTCGAAGGCGGATTAA

Upstream 100 bases:

>100_bases
CGGACGCGGGCACGCGTATCACCGACGGCTGCGAAGTCGCGTTTTTTCCGCCCGTGACGGGCGGCTGACAAAGGGCCGCA
AAGGCAGCGAGGAACTGACG

Downstream 100 bases:

>100_bases
AGTTATTCGTTGAACGCTTCAACAAATAACGGCGGCTCTATTATCGGTCCCCTTTGTTAAATCCCGATTGCTGAACCGCA
ATTGTTAAATTGGCGCCGTT

Product: molybdopterin biosynthesis MoaE protein

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MTVRVQTEDFDLSTEVAALRAQNPKVGAVACFVGTVRDINEGETVETMELEHYPGMTEKSLEAIVDAARERWPGTEVLIV
HRVGKLQPLDQIVLVATTSKHRGNAFASCEFVMDYLKTQAPFWKKEKTESGERWVDARVADEQALARWGLESLNSKAD

Sequences:

>Translated_158_residues
MTVRVQTEDFDLSTEVAALRAQNPKVGAVACFVGTVRDINEGETVETMELEHYPGMTEKSLEAIVDAARERWPGTEVLIV
HRVGKLQPLDQIVLVATTSKHRGNAFASCEFVMDYLKTQAPFWKKEKTESGERWVDARVADEQALARWGLESLNSKAD
>Mature_157_residues
TVRVQTEDFDLSTEVAALRAQNPKVGAVACFVGTVRDINEGETVETMELEHYPGMTEKSLEAIVDAARERWPGTEVLIVH
RVGKLQPLDQIVLVATTSKHRGNAFASCEFVMDYLKTQAPFWKKEKTESGERWVDARVADEQALARWGLESLNSKAD

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=112, Percent_Identity=33.0357142857143, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI1787003, Length=144, Percent_Identity=52.0833333333333, Blast_Score=157, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17509279, Length=111, Percent_Identity=32.4324324324324, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21356259, Length=102, Percent_Identity=37.2549019607843, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17665; Mature: 17534

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRVQTEDFDLSTEVAALRAQNPKVGAVACFVGTVRDINEGETVETMELEHYPGMTEKS
CEEEEECCCCCCHHHHHHHHCCCCCCCCHHEEHHHHHCCCCCCCEEEEECCCCCCCCHHH
LEAIVDAARERWPGTEVLIVHRVGKLQPLDQIVLVATTSKHRGNAFASCEFVMDYLKTQA
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCC
PFWKKEKTESGERWVDARVADEQALARWGLESLNSKAD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCC
>Mature Secondary Structure 
TVRVQTEDFDLSTEVAALRAQNPKVGAVACFVGTVRDINEGETVETMELEHYPGMTEKS
EEEEECCCCCCHHHHHHHHCCCCCCCCHHEEHHHHHCCCCCCCEEEEECCCCCCCCHHH
LEAIVDAARERWPGTEVLIVHRVGKLQPLDQIVLVATTSKHRGNAFASCEFVMDYLKTQA
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCC
PFWKKEKTESGERWVDARVADEQALARWGLESLNSKAD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]