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The map label for this gene is glnS [H]

Identifier: 186475672

GI number: 186475672

Start: 1009819

End: 1011540

Strand: Reverse

Name: glnS [H]

Synonym: Bphy_0907

Alternate gene names: 186475672

Gene position: 1011540-1009819 (Counterclockwise)

Preceding gene: 186475673

Following gene: 186475671

Centisome position: 29.07

GC content: 61.5

Gene sequence:

>1722_bases
ATGAACAACGAACGCAAAGACGCCGAGCGCCACGACGCGCCCGTTTCCAACTTCATCCGCAACATCATTGACGACGACAA
CCGCTCTGGAAAGTGGGGCCAGCGGGTGGAGACGCGCTTCCCGCCGGAACCGAACGGTTATCTGCACATCGGCCATGCGA
AGAGCATCTGCCTGAACTTCGGCATTGCGCAAAGCTACGGCGGCATCTGTCATCTGCGCTTCGACGACACGAATCCGGAG
AAGGAAAGCTTCGAGTACGTCGACTCGATCGTCGACGCCGTGAAGTGGCTCGGCTTCGAATGGAAGTCGGAGCAGCGGGA
GCACCTGTACTTCGCGAGCGACTACTACGACAAGCTGTACGAGTTCGCCGAGCTGCTGATCACGCGCGGCAAGGCGTACG
TCGACAGCCAGAGCGCGGAAGAAATGCGCGCGAACCGCGGCTCGGCGACGGAAGTCGGCACGCCGTCACCGTTCCGCGAG
CGCAGCGTCGAAGAGAACCTGGACCTGTTCCGCCGCATGAAGGCAGGCGAGTTCAAGGAAGGCGAGCACGTGCTGCGCGC
GAAGATCGACATGTCGTCGCCGAACTTCAACATGCGCGACCCGGTGATCTATCGCATCCGCTTCGCCCACCACTACCGGA
CGGGCGACACGTGGTGCGTGTATCCGATGTACGACTACACGCATTGCATTTCGGACGCGCTCGAAAACATCACGCATTCG
CTGTGTACGCTCGAATTCGAAGACCACCGCCCGTTGTACGACTGGATCCTCAACGAGCTCGCCAACGCGGGCATCTTCAC
GCGTCCGCTGCCGCAGCAGATCGAATTTTCGCGCCTGAATCTCACGTACGCGATCACCAGCAAGCGCAAGCTGCTGCAAC
TCGTGAACGAAGGCCATGTGGACGGCTGGGACGATCCGCGCATGCCGACCATCGTCGGCGTGCGCCGGCGCGGCTTCACG
CCGGAAGGCATCAAGTTGTTCTGCGAGCGCATCGGTATCACGAAGGTCGATTCGTGGATCGACATGAGCGTGTTCGAGGG
CGCGCTGCGCGACGATCTGGATGAAAAGGCGCCGCGCGCGACCTGCGTGCTCGATCCGCTGAAGCTCGTCATCGACAACT
ACCCGGAAGGACAGACGGAAGAATGCAGCGCGCCCGTCCACCCGCATCACCCGGATCGCGGCTTGCGTACGTTTCCGTTC
TCGCGCGAACTGTGGATCGAGCGCGAAGACTTCATGGAGAACGCGCCGAAGGGCTATTTCCGCCTGTTCCCAGGCAACAA
GGTGCGGCTGAAGTACGGCTACGTCGTCGAATGCACGGGCGCGGAAAAGGACGAGAACGGCAACGTGATCGCCGTGCACT
GCAACTACTTCGCGGATAGCCGCTCGGGCACGGAAGGCGCGAACAACTACAAGGTGAAGGGCACGATTCACTGGATCAGC
GCGACTCAGGCTGTGCCCGTCGAGGTGCGCATCTACGATCGCCTGTTCAGGGAAGCGCAGCCCGACGCGGGCGGCCGCGA
TTTCCTCGAGGCGCTCAATCCCGATTCGAAGCGCATCGTGCAGGCGTTCGTCGAGCCGGGTCTGCGCGACATAGAACCAG
AGCAGCGCTATCAGTTCGAGCGTCACGGCTACTTCGTTGCCGACCGATATGACACGAAGCCGGGCAAACCCATATTCAAC
CGGATCGTCAGTCTGCGCGACAGTTGGGGAAAGCCGGCGTAA

Upstream 100 bases:

>100_bases
CACTCCACACGCCTAAAGCCTGTCGTCGAATGTGTGGTCAGGTAGAATTGACAGACTAACGGACACATATAGTGTCCAGG
ACCGACTTTCTCCTTCTCGC

Downstream 100 bases:

>100_bases
GCTGATTGTCTGGTTGCGTCATGCACGGCATGCGGCGTTTCCAGCGCGCATGCTCGCGTGGCACACGATGGACATCGCCT
GCCAGAGCATGACGATGCAG

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MNNERKDAERHDAPVSNFIRNIIDDDNRSGKWGQRVETRFPPEPNGYLHIGHAKSICLNFGIAQSYGGICHLRFDDTNPE
KESFEYVDSIVDAVKWLGFEWKSEQREHLYFASDYYDKLYEFAELLITRGKAYVDSQSAEEMRANRGSATEVGTPSPFRE
RSVEENLDLFRRMKAGEFKEGEHVLRAKIDMSSPNFNMRDPVIYRIRFAHHYRTGDTWCVYPMYDYTHCISDALENITHS
LCTLEFEDHRPLYDWILNELANAGIFTRPLPQQIEFSRLNLTYAITSKRKLLQLVNEGHVDGWDDPRMPTIVGVRRRGFT
PEGIKLFCERIGITKVDSWIDMSVFEGALRDDLDEKAPRATCVLDPLKLVIDNYPEGQTEECSAPVHPHHPDRGLRTFPF
SRELWIEREDFMENAPKGYFRLFPGNKVRLKYGYVVECTGAEKDENGNVIAVHCNYFADSRSGTEGANNYKVKGTIHWIS
ATQAVPVEVRIYDRLFREAQPDAGGRDFLEALNPDSKRIVQAFVEPGLRDIEPEQRYQFERHGYFVADRYDTKPGKPIFN
RIVSLRDSWGKPA

Sequences:

>Translated_573_residues
MNNERKDAERHDAPVSNFIRNIIDDDNRSGKWGQRVETRFPPEPNGYLHIGHAKSICLNFGIAQSYGGICHLRFDDTNPE
KESFEYVDSIVDAVKWLGFEWKSEQREHLYFASDYYDKLYEFAELLITRGKAYVDSQSAEEMRANRGSATEVGTPSPFRE
RSVEENLDLFRRMKAGEFKEGEHVLRAKIDMSSPNFNMRDPVIYRIRFAHHYRTGDTWCVYPMYDYTHCISDALENITHS
LCTLEFEDHRPLYDWILNELANAGIFTRPLPQQIEFSRLNLTYAITSKRKLLQLVNEGHVDGWDDPRMPTIVGVRRRGFT
PEGIKLFCERIGITKVDSWIDMSVFEGALRDDLDEKAPRATCVLDPLKLVIDNYPEGQTEECSAPVHPHHPDRGLRTFPF
SRELWIEREDFMENAPKGYFRLFPGNKVRLKYGYVVECTGAEKDENGNVIAVHCNYFADSRSGTEGANNYKVKGTIHWIS
ATQAVPVEVRIYDRLFREAQPDAGGRDFLEALNPDSKRIVQAFVEPGLRDIEPEQRYQFERHGYFVADRYDTKPGKPIFN
RIVSLRDSWGKPA
>Mature_573_residues
MNNERKDAERHDAPVSNFIRNIIDDDNRSGKWGQRVETRFPPEPNGYLHIGHAKSICLNFGIAQSYGGICHLRFDDTNPE
KESFEYVDSIVDAVKWLGFEWKSEQREHLYFASDYYDKLYEFAELLITRGKAYVDSQSAEEMRANRGSATEVGTPSPFRE
RSVEENLDLFRRMKAGEFKEGEHVLRAKIDMSSPNFNMRDPVIYRIRFAHHYRTGDTWCVYPMYDYTHCISDALENITHS
LCTLEFEDHRPLYDWILNELANAGIFTRPLPQQIEFSRLNLTYAITSKRKLLQLVNEGHVDGWDDPRMPTIVGVRRRGFT
PEGIKLFCERIGITKVDSWIDMSVFEGALRDDLDEKAPRATCVLDPLKLVIDNYPEGQTEECSAPVHPHHPDRGLRTFPF
SRELWIEREDFMENAPKGYFRLFPGNKVRLKYGYVVECTGAEKDENGNVIAVHCNYFADSRSGTEGANNYKVKGTIHWIS
ATQAVPVEVRIYDRLFREAQPDAGGRDFLEALNPDSKRIVQAFVEPGLRDIEPEQRYQFERHGYFVADRYDTKPGKPIFN
RIVSLRDSWGKPA

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=546, Percent_Identity=43.7728937728938, Blast_Score=428, Evalue=1e-120,
Organism=Homo sapiens, GI62241042, Length=519, Percent_Identity=35.645472061657, Blast_Score=281, Evalue=1e-75,
Organism=Escherichia coli, GI1786895, Length=561, Percent_Identity=56.3279857397504, Blast_Score=639, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=112, Percent_Identity=32.1428571428571, Blast_Score=73, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17543332, Length=545, Percent_Identity=42.0183486238532, Blast_Score=392, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17511007, Length=525, Percent_Identity=32.3809523809524, Blast_Score=238, Evalue=5e-63,
Organism=Saccharomyces cerevisiae, GI6324742, Length=578, Percent_Identity=42.3875432525952, Blast_Score=421, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6321192, Length=534, Percent_Identity=34.2696629213483, Blast_Score=280, Evalue=5e-76,
Organism=Drosophila melanogaster, GI17864488, Length=549, Percent_Identity=40.8014571948998, Blast_Score=414, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24649466, Length=518, Percent_Identity=33.3976833976834, Blast_Score=251, Evalue=1e-66,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 66342; Mature: 66342

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNERKDAERHDAPVSNFIRNIIDDDNRSGKWGQRVETRFPPEPNGYLHIGHAKSICLNF
CCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHCC
GIAQSYGGICHLRFDDTNPEKESFEYVDSIVDAVKWLGFEWKSEQREHLYFASDYYDKLY
CHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHH
EFAELLITRGKAYVDSQSAEEMRANRGSATEVGTPSPFRERSVEENLDLFRRMKAGEFKE
HHHHHHHHCCCHHCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
GEHVLRAKIDMSSPNFNMRDPVIYRIRFAHHYRTGDTWCVYPMYDYTHCISDALENITHS
CCEEEEEEEECCCCCCCCCCCEEEEEEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHH
LCTLEFEDHRPLYDWILNELANAGIFTRPLPQQIEFSRLNLTYAITSKRKLLQLVNEGHV
HEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHCCCC
DGWDDPRMPTIVGVRRRGFTPEGIKLFCERIGITKVDSWIDMSVFEGALRDDLDEKAPRA
CCCCCCCCCCEEEHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCHHHHCCCC
TCVLDPLKLVIDNYPEGQTEECSAPVHPHHPDRGLRTFPFSRELWIEREDFMENAPKGYF
EEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHCCCCCCEE
RLFPGNKVRLKYGYVVECTGAEKDENGNVIAVHCNYFADSRSGTEGANNYKVKGTIHWIS
EECCCCEEEEEEEEEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCEEEEEEEEEEE
ATQAVPVEVRIYDRLFREAQPDAGGRDFLEALNPDSKRIVQAFVEPGLRDIEPEQRYQFE
CCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHH
RHGYFVADRYDTKPGKPIFNRIVSLRDSWGKPA
HCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNNERKDAERHDAPVSNFIRNIIDDDNRSGKWGQRVETRFPPEPNGYLHIGHAKSICLNF
CCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHCC
GIAQSYGGICHLRFDDTNPEKESFEYVDSIVDAVKWLGFEWKSEQREHLYFASDYYDKLY
CHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHH
EFAELLITRGKAYVDSQSAEEMRANRGSATEVGTPSPFRERSVEENLDLFRRMKAGEFKE
HHHHHHHHCCCHHCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
GEHVLRAKIDMSSPNFNMRDPVIYRIRFAHHYRTGDTWCVYPMYDYTHCISDALENITHS
CCEEEEEEEECCCCCCCCCCCEEEEEEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHH
LCTLEFEDHRPLYDWILNELANAGIFTRPLPQQIEFSRLNLTYAITSKRKLLQLVNEGHV
HEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHCCCC
DGWDDPRMPTIVGVRRRGFTPEGIKLFCERIGITKVDSWIDMSVFEGALRDDLDEKAPRA
CCCCCCCCCCEEEHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCHHHHCCCC
TCVLDPLKLVIDNYPEGQTEECSAPVHPHHPDRGLRTFPFSRELWIEREDFMENAPKGYF
EEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHCCCCCCEE
RLFPGNKVRLKYGYVVECTGAEKDENGNVIAVHCNYFADSRSGTEGANNYKVKGTIHWIS
EECCCCEEEEEEEEEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCEEEEEEEEEEE
ATQAVPVEVRIYDRLFREAQPDAGGRDFLEALNPDSKRIVQAFVEPGLRDIEPEQRYQFE
CCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHH
RHGYFVADRYDTKPGKPIFNRIVSLRDSWGKPA
HCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA