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The map label for this gene is era [H]

Identifier: 186475607

GI number: 186475607

Start: 941499

End: 942362

Strand: Direct

Name: era [H]

Synonym: Bphy_0842

Alternate gene names: 186475607

Gene position: 941499-942362 (Clockwise)

Preceding gene: 186475606

Following gene: 186475608

Centisome position: 27.06

GC content: 59.84

Gene sequence:

>864_bases
ATGGTCGCGATCGTCGGCCGTCCGAACGTCGGCAAGTCGACGCTGATGAACGCGCTCGTCGGACAGAAAGTCAGCATCAC
GTCGCGCAAGGCGCAGACGACGCGCCATCGCATTACGGGTATCAATACGCTCGACGACGCGCAGTACATCTTCGTCGACA
CACCCGGCTTCCAGACCCGTCATAGCGGAGCGTTGAACCGCTCGCTCAATCGCGCGGTGACGTCGACGCTGACCTCCGTC
GATGCCGTGTTGTTCGTGATCGAAGCCGGACGCTTCGGTCCCGACGACCAGAAAGTGCTCGACCTGATTCCCGCTTCTGC
GCCGACGCTGCTCATCGCGAACAAACTCGACCGCGTGAGCGACAAGGATTCGTTGTTTCCGTTCATGCAGCAGATGAGTG
CGGCGCGCGAGTTCAAGGAAATCGTGCCGCTATCGGCCAGGAATCCCGACGACATCAAGCGTCTGCTGACGACAGTCAAG
CCGTATCTGCCGCAGGGCGATCCGATCTACGGCGAAGACGACCTGACCGATCGCAGCGAGCGTTTCCTTGCCGCCGAAAT
CCTGCGCGAAAAGGTGTTCCGCTGGACAGGCGACGAACTGCCGTACACCAGCACCGTGCTGATCGACAAGTTTGAGACGG
AAGGGCGCCTGCGGCGCATTTTTGCAACGATTCTCGTCGAGCGCGATACGCACAAGGCGATGATCATCGGCCAGAAGGGC
GCCAAGTTGAAGCAGATCAGCTCGGAAGCGCGCCTTGACATGGAAAAGCTGTTCGACGGCCCGGTGTATCTCGAGACGTT
CATCAAGGTGAAGAGTGGCTGGGCGGACAATGAAGCCGGACTCCGTGCCTATGGTTACGAATGA

Upstream 100 bases:

>100_bases
ACGCAATATCACGTGAATGCGCGCTCGATGATGCGCGCCCACCCGAACCTGCCGTAGTACGAATATGAACGCTTCCACTC
CCACTGGTTTCCGCTGCGGC

Downstream 100 bases:

>100_bases
GATTACGCATGATGACGCCTCGGGTACCCGCGCCGACGCGTGGATGACGCTGCCGGCCGAAGCCGATCCTGACGTCGACT
CCGACGACGCCACGGGCGCG

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MVAIVGRPNVGKSTLMNALVGQKVSITSRKAQTTRHRITGINTLDDAQYIFVDTPGFQTRHSGALNRSLNRAVTSTLTSV
DAVLFVIEAGRFGPDDQKVLDLIPASAPTLLIANKLDRVSDKDSLFPFMQQMSAAREFKEIVPLSARNPDDIKRLLTTVK
PYLPQGDPIYGEDDLTDRSERFLAAEILREKVFRWTGDELPYTSTVLIDKFETEGRLRRIFATILVERDTHKAMIIGQKG
AKLKQISSEARLDMEKLFDGPVYLETFIKVKSGWADNEAGLRAYGYE

Sequences:

>Translated_287_residues
MVAIVGRPNVGKSTLMNALVGQKVSITSRKAQTTRHRITGINTLDDAQYIFVDTPGFQTRHSGALNRSLNRAVTSTLTSV
DAVLFVIEAGRFGPDDQKVLDLIPASAPTLLIANKLDRVSDKDSLFPFMQQMSAAREFKEIVPLSARNPDDIKRLLTTVK
PYLPQGDPIYGEDDLTDRSERFLAAEILREKVFRWTGDELPYTSTVLIDKFETEGRLRRIFATILVERDTHKAMIIGQKG
AKLKQISSEARLDMEKLFDGPVYLETFIKVKSGWADNEAGLRAYGYE
>Mature_287_residues
MVAIVGRPNVGKSTLMNALVGQKVSITSRKAQTTRHRITGINTLDDAQYIFVDTPGFQTRHSGALNRSLNRAVTSTLTSV
DAVLFVIEAGRFGPDDQKVLDLIPASAPTLLIANKLDRVSDKDSLFPFMQQMSAAREFKEIVPLSARNPDDIKRLLTTVK
PYLPQGDPIYGEDDLTDRSERFLAAEILREKVFRWTGDELPYTSTVLIDKFETEGRLRRIFATILVERDTHKAMIIGQKG
AKLKQISSEARLDMEKLFDGPVYLETFIKVKSGWADNEAGLRAYGYE

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=315, Percent_Identity=26.984126984127, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1788919, Length=287, Percent_Identity=50.1742160278746, Blast_Score=288, Evalue=2e-79,
Organism=Escherichia coli, GI87082120, Length=161, Percent_Identity=29.8136645962733, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646434, Length=301, Percent_Identity=24.9169435215947, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 32124; Mature: 32124

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAIVGRPNVGKSTLMNALVGQKVSITSRKAQTTRHRITGINTLDDAQYIFVDTPGFQTR
CEEEECCCCCCHHHHHHHHHCCCEEECHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCC
HSGALNRSLNRAVTSTLTSVDAVLFVIEAGRFGPDDQKVLDLIPASAPTLLIANKLDRVS
CCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHCC
DKDSLFPFMQQMSAAREFKEIVPLSARNPDDIKRLLTTVKPYLPQGDPIYGEDDLTDRSE
CHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
RFLAAEILREKVFRWTGDELPYTSTVLIDKFETEGRLRRIFATILVERDTHKAMIIGQKG
HHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEECCC
AKLKQISSEARLDMEKLFDGPVYLETFIKVKSGWADNEAGLRAYGYE
CHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHCCCCCCCCCCEECCCC
>Mature Secondary Structure
MVAIVGRPNVGKSTLMNALVGQKVSITSRKAQTTRHRITGINTLDDAQYIFVDTPGFQTR
CEEEECCCCCCHHHHHHHHHCCCEEECHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCC
HSGALNRSLNRAVTSTLTSVDAVLFVIEAGRFGPDDQKVLDLIPASAPTLLIANKLDRVS
CCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHCC
DKDSLFPFMQQMSAAREFKEIVPLSARNPDDIKRLLTTVKPYLPQGDPIYGEDDLTDRSE
CHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
RFLAAEILREKVFRWTGDELPYTSTVLIDKFETEGRLRRIFATILVERDTHKAMIIGQKG
HHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEECCC
AKLKQISSEARLDMEKLFDGPVYLETFIKVKSGWADNEAGLRAYGYE
CHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHCCCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]