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The map label for this gene is fabD [H]

Identifier: 186475594

GI number: 186475594

Start: 928509

End: 929441

Strand: Direct

Name: fabD [H]

Synonym: Bphy_0829

Alternate gene names: 186475594

Gene position: 928509-929441 (Clockwise)

Preceding gene: 186475593

Following gene: 186475595

Centisome position: 26.69

GC content: 64.42

Gene sequence:

>933_bases
ATGAAATTTGCGTTCGTTTTTCCGGGGCAGGGCTCGCAGGCGGTCGGCATGCTCAATGCGTTCGCCGACAACGCGATCGT
GCGCGAAACCCTCCAGGAAGCGTCCGACGCGCTCAACCAGGATATCGGCAAGCTGATCGCCGAGGGCCCGGCTGAAGACC
TGAATCTGACCACCAACACCCAACCTGTGATGCTGACGGCTGCTTACGCAATCTTTCGCGCATGGCAAGCGGCAGGTGGT
CCTGCGCCTACAATCGTGGCCGGCCACAGCCTCGGCGAATACACGGCGCTGGTCGCCGGCGGCGCGTTGAAGTTCCGCGA
CGCGGTGCCGCTCGTGCGTTTTCGTGCGCAGGCCATGCAGAATGCAGTGCCCGTCGGCCAAGGCGGCATGGCTGCGATTC
TCGGCCTCGACGACGACACCGTGCGCGAAGTTTGCAAGGAAGCATCGGCGGCAGGCGTCGTGGAAGCTGTCAACTTTAAC
GCGCCTGCGCAGGTTGTGATCGCCGGTCACAAGGCCGCCGTTGAAAAGGCGTGCGAAGTCGCGAAGGCAAAGGGTGCGAA
GCGCGCGCTGCCGCTGCCCGTGTCCGCGCCGTTCCATTCGTCGCTGCTCAAGCCCGCGTCGGATCAGCTGCGCGAGTACC
TGGCGAGCGTCGACGTGCAGGTGCCGTCCATCCCCGTCGTGAACAACGTCGACGTGGCTATCGTCAACGAGCCGGCCGGC
ATCAAGGATGCGCTGGTGCGTCAGGCGGCGGGTGCCGTGCGCTGGGTCGAATGCGTGCAGTCCATCGCGAAACAGGGCGT
CACGCATGTGATCGAATGTGGTCCCGGCAAGGTGCTGGCGGGTCTGACCAAGCGTATTGACGCTAACCTGGTCGGCGCGG
CAATCGTCGATCCCGCCACCCTCGACGAAGTGCTGAAAGTCGTCTCGGCCTGA

Upstream 100 bases:

>100_bases
TTACTGATGGCCGCGCGCAGCGGCGCCAGACGCCGCTTCAAGCCGTAGCGCACGCCATGCGTGCATCACGCACATTTGAA
CTCATCGAATTGGGGACGAT

Downstream 100 bases:

>100_bases
ACGTCCATTTGTGCGGCAGCAACGAATCAAACAGCCTGCGTGTGCAGGGAATGCGGAATTGAACGATGGAAAAGACTCTC
GATAAACAGATCGCGATCGT

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKFAFVFPGQGSQAVGMLNAFADNAIVRETLQEASDALNQDIGKLIAEGPAEDLNLTTNTQPVMLTAAYAIFRAWQAAGG
PAPTIVAGHSLGEYTALVAGGALKFRDAVPLVRFRAQAMQNAVPVGQGGMAAILGLDDDTVREVCKEASAAGVVEAVNFN
APAQVVIAGHKAAVEKACEVAKAKGAKRALPLPVSAPFHSSLLKPASDQLREYLASVDVQVPSIPVVNNVDVAIVNEPAG
IKDALVRQAAGAVRWVECVQSIAKQGVTHVIECGPGKVLAGLTKRIDANLVGAAIVDPATLDEVLKVVSA

Sequences:

>Translated_310_residues
MKFAFVFPGQGSQAVGMLNAFADNAIVRETLQEASDALNQDIGKLIAEGPAEDLNLTTNTQPVMLTAAYAIFRAWQAAGG
PAPTIVAGHSLGEYTALVAGGALKFRDAVPLVRFRAQAMQNAVPVGQGGMAAILGLDDDTVREVCKEASAAGVVEAVNFN
APAQVVIAGHKAAVEKACEVAKAKGAKRALPLPVSAPFHSSLLKPASDQLREYLASVDVQVPSIPVVNNVDVAIVNEPAG
IKDALVRQAAGAVRWVECVQSIAKQGVTHVIECGPGKVLAGLTKRIDANLVGAAIVDPATLDEVLKVVSA
>Mature_310_residues
MKFAFVFPGQGSQAVGMLNAFADNAIVRETLQEASDALNQDIGKLIAEGPAEDLNLTTNTQPVMLTAAYAIFRAWQAAGG
PAPTIVAGHSLGEYTALVAGGALKFRDAVPLVRFRAQAMQNAVPVGQGGMAAILGLDDDTVREVCKEASAAGVVEAVNFN
APAQVVIAGHKAAVEKACEVAKAKGAKRALPLPVSAPFHSSLLKPASDQLREYLASVDVQVPSIPVVNNVDVAIVNEPAG
IKDALVRQAAGAVRWVECVQSIAKQGVTHVIECGPGKVLAGLTKRIDANLVGAAIVDPATLDEVLKVVSA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=301, Percent_Identity=31.5614617940199, Blast_Score=140, Evalue=1e-33,
Organism=Escherichia coli, GI1787334, Length=307, Percent_Identity=54.7231270358306, Blast_Score=310, Evalue=1e-85,
Organism=Caenorhabditis elegans, GI17550940, Length=294, Percent_Identity=31.6326530612245, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71984332, Length=301, Percent_Identity=29.9003322259136, Blast_Score=118, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24665753, Length=300, Percent_Identity=33.6666666666667, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32010; Mature: 32010

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAFVFPGQGSQAVGMLNAFADNAIVRETLQEASDALNQDIGKLIAEGPAEDLNLTTNT
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
QPVMLTAAYAIFRAWQAAGGPAPTIVAGHSLGEYTALVAGGALKFRDAVPLVRFRAQAMQ
CCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCCCEEHHHHHHHHHHHHHHHH
NAVPVGQGGMAAILGLDDDTVREVCKEASAAGVVEAVNFNAPAQVVIAGHKAAVEKACEV
HCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCEEEEECCCCCEEEEEECCHHHHHHHHHH
AKAKGAKRALPLPVSAPFHSSLLKPASDQLREYLASVDVQVPSIPVVNNVDVAIVNEPAG
HHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCC
IKDALVRQAAGAVRWVECVQSIAKQGVTHVIECGPGKVLAGLTKRIDANLVGAAIVDPAT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHCCHHH
LDEVLKVVSA
HHHHHHHHCC
>Mature Secondary Structure
MKFAFVFPGQGSQAVGMLNAFADNAIVRETLQEASDALNQDIGKLIAEGPAEDLNLTTNT
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
QPVMLTAAYAIFRAWQAAGGPAPTIVAGHSLGEYTALVAGGALKFRDAVPLVRFRAQAMQ
CCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCCCEEHHHHHHHHHHHHHHHH
NAVPVGQGGMAAILGLDDDTVREVCKEASAAGVVEAVNFNAPAQVVIAGHKAAVEKACEV
HCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCEEEEECCCCCEEEEEECCHHHHHHHHHH
AKAKGAKRALPLPVSAPFHSSLLKPASDQLREYLASVDVQVPSIPVVNNVDVAIVNEPAG
HHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCC
IKDALVRQAAGAVRWVECVQSIAKQGVTHVIECGPGKVLAGLTKRIDANLVGAAIVDPAT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHCCHHH
LDEVLKVVSA
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]