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The map label for this gene is cobD [H]

Identifier: 186475539

GI number: 186475539

Start: 869630

End: 870568

Strand: Direct

Name: cobD [H]

Synonym: Bphy_0774

Alternate gene names: 186475539

Gene position: 869630-870568 (Clockwise)

Preceding gene: 186475538

Following gene: 186475543

Centisome position: 25.0

GC content: 63.9

Gene sequence:

>939_bases
ATGACTTTTTTCTCCGTATTGCTGGCCCTCATCCTCGAACAGGTGCGCGCGCTGTCGCCGAACAACCCGGTGTCGGCGCT
CCTTCAATACCATGCGGAGTCGACCGCACACGGCTTCGATGCCGGCAAGGAAAAGCACGGGTTCCTCGCGTGGCTCGTCG
TCGTGCTGCCCTGGACGCTCGTCACGGGCCTGATCTACTTCGTGCTCTATGAGATTCACTTTGTGCTCGCGTTCCTGTGG
AACGTTGCGGTGCTGTACTTCACGCTCGGCTTTCGCCAGTTCAGCCATTACTTCACCGACATCCATTTGTCGCTGAACAA
CGACGACGTGCCGCGAGCGCGTGAAATCCTCAACGAATGGACGGGCCTCGATACCGTCGACATGCCCGTGAGCGAGATCG
TGCGCCACACGTTGATTCACGCCGTCGTCGCGTCGCATCGACATGTGTTCGGCGTGTTCTTCTGGTTCCTGATTCCCGTC
GGCCCGGCGGGCGCGGTGCTGTATCGCACGGCCGAGTATCTCGCGCGCACGTGGTCGAAGCCCACCGACGACCGGACCGT
TGCGTTCTCCACCTTCGCGCAGCGCGCGTTCTTCGTGATCGACTGGATTCCGTCGCGTTTGACGTCGCTCGGTTTTGCGA
TCGTCGGCAATTTCGAGGACGCGATCTATGCGTGGCGCAACCACGCGCGCCAATGGCCCGATGCGAACGACGGCGTGTTG
CTCGCCGCGGGCAGCGGCGCGTTGGGCGCACGTCTGGCGGGCCCGCTCGCGGAAGTATCGAGCCTCGACGCGCTGGCGAC
GGGCGACGGCGGCCCGATGCCCGTCGGCGACGACTGCACGCCGCGCACGCTGCAATCGGCGGTGGGCCTTGTATGGCGGG
CGGTGATCCTGTGGATGATCCTGCTGCTGATGCTGACCATCGCCGTCTGGCTCGCCTGA

Upstream 100 bases:

>100_bases
TCATCCGACCCTGTGCTATCGTAATAACGAATTCCGCTTATCGGACCAGACCGTCCGGCACTCATTGCCCGGCAAGAACT
CGAATAGCACGGCGTCTCGC

Downstream 100 bases:

>100_bases
GCCGAAACGCTGGCACATTGACGCGACAAAACGTCGACGCGGAAAGGCGCGCTCAACCGTCCAGAGGATCACGCGCCGTT
CCGCAGTTCTAGCACACGGT

Product: CobD/CbiB family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MTFFSVLLALILEQVRALSPNNPVSALLQYHAESTAHGFDAGKEKHGFLAWLVVVLPWTLVTGLIYFVLYEIHFVLAFLW
NVAVLYFTLGFRQFSHYFTDIHLSLNNDDVPRAREILNEWTGLDTVDMPVSEIVRHTLIHAVVASHRHVFGVFFWFLIPV
GPAGAVLYRTAEYLARTWSKPTDDRTVAFSTFAQRAFFVIDWIPSRLTSLGFAIVGNFEDAIYAWRNHARQWPDANDGVL
LAAGSGALGARLAGPLAEVSSLDALATGDGGPMPVGDDCTPRTLQSAVGLVWRAVILWMILLLMLTIAVWLA

Sequences:

>Translated_312_residues
MTFFSVLLALILEQVRALSPNNPVSALLQYHAESTAHGFDAGKEKHGFLAWLVVVLPWTLVTGLIYFVLYEIHFVLAFLW
NVAVLYFTLGFRQFSHYFTDIHLSLNNDDVPRAREILNEWTGLDTVDMPVSEIVRHTLIHAVVASHRHVFGVFFWFLIPV
GPAGAVLYRTAEYLARTWSKPTDDRTVAFSTFAQRAFFVIDWIPSRLTSLGFAIVGNFEDAIYAWRNHARQWPDANDGVL
LAAGSGALGARLAGPLAEVSSLDALATGDGGPMPVGDDCTPRTLQSAVGLVWRAVILWMILLLMLTIAVWLA
>Mature_311_residues
TFFSVLLALILEQVRALSPNNPVSALLQYHAESTAHGFDAGKEKHGFLAWLVVVLPWTLVTGLIYFVLYEIHFVLAFLWN
VAVLYFTLGFRQFSHYFTDIHLSLNNDDVPRAREILNEWTGLDTVDMPVSEIVRHTLIHAVVASHRHVFGVFFWFLIPVG
PAGAVLYRTAEYLARTWSKPTDDRTVAFSTFAQRAFFVIDWIPSRLTSLGFAIVGNFEDAIYAWRNHARQWPDANDGVLL
AAGSGALGARLAGPLAEVSSLDALATGDGGPMPVGDDCTPRTLQSAVGLVWRAVILWMILLLMLTIAVWLA

Specific function: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group [H]

COG id: COG1270

COG function: function code H; Cobalamin biosynthesis protein CobD/CbiB

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobD/CbiB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004485 [H]

Pfam domain/function: PF03186 CobD_Cbib [H]

EC number: NA

Molecular weight: Translated: 34682; Mature: 34551

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFFSVLLALILEQVRALSPNNPVSALLQYHAESTAHGFDAGKEKHGFLAWLVVVLPWTL
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
VTGLIYFVLYEIHFVLAFLWNVAVLYFTLGFRQFSHYFTDIHLSLNNDDVPRAREILNEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHH
TGLDTVDMPVSEIVRHTLIHAVVASHRHVFGVFFWFLIPVGPAGAVLYRTAEYLARTWSK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
PTDDRTVAFSTFAQRAFFVIDWIPSRLTSLGFAIVGNFEDAIYAWRNHARQWPDANDGVL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEE
LAAGSGALGARLAGPLAEVSSLDALATGDGGPMPVGDDCTPRTLQSAVGLVWRAVILWMI
EEECCCCCHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LLLMLTIAVWLA
HHHHHHHHHHCC
>Mature Secondary Structure 
TFFSVLLALILEQVRALSPNNPVSALLQYHAESTAHGFDAGKEKHGFLAWLVVVLPWTL
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
VTGLIYFVLYEIHFVLAFLWNVAVLYFTLGFRQFSHYFTDIHLSLNNDDVPRAREILNEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHH
TGLDTVDMPVSEIVRHTLIHAVVASHRHVFGVFFWFLIPVGPAGAVLYRTAEYLARTWSK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
PTDDRTVAFSTFAQRAFFVIDWIPSRLTSLGFAIVGNFEDAIYAWRNHARQWPDANDGVL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEE
LAAGSGALGARLAGPLAEVSSLDALATGDGGPMPVGDDCTPRTLQSAVGLVWRAVILWMI
EEECCCCCHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LLLMLTIAVWLA
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA