BacMap

Definition	Burkholderia phymatum STM815 chromosome chromosome 1, complete sequence.
Accession	NC_010622
Length	3,479,187

Click here to switch to the map view.

The map label for this gene is fabG [H]

Identifier: 186475467

GI number: 186475467

Start: 789218

End: 789943

Strand: Direct

Name: fabG [H]

Synonym: Bphy_0702

Alternate gene names: 186475467

Gene position: 789218-789943 (Clockwise)

Preceding gene: 186475466

Following gene: 186475468

Centisome position: 22.68

GC content: 66.8

Gene sequence:

>726_bases
ATGAGCCGCCGAGTTCTCGTAACGGGCGCGAGCCGCGGCATTGGCCGCGCGATTGCCTATCAGCTGGCTGCCGACGGCTT
CGCCGTGTCCGTGCATTGCCGCACGGGCCGCACGGAAGCCGAAGCCGTCACGGCGGGCATTGCGGCGCAGGGCGGCTCGG
CGCGCGTGCTGCAGTTCGACGTGCGCGAGCGCGCCGCGTGCCGCGACGCGCTTGAAGCGGATGTCGCCGCGCACGGCCCG
TACTACGGCATCGTGTGCAGCGCGGGTGTGACGCGCGACGCGGCCTTTCCCGCGCTCACCGACGAAGACTGGGACGTGGT
GATCGAAACCGGCCTCGACGCGTTCTATAACGTAATCCATCCGCTGACGATGCCGATGGTCCGTGCCAAAAAAGGCGGCC
GCATTGTGACGATCGCATCGGTGTCGGGTGTGATCGGCAATCGCGGCCAGGTCAACTACAGCGCGGCGAAAGCGGGGCTG
ATCGGCGCGACGAAGGCGCTGGCCGTCGAACTCGCATCGCGCAGCATCACGGTCAACTGCGTGGCGCCGGGGCTGATCGA
AACGGGCATGCTCCAGGACATGCCGCTCGAACACGCGCTGAAAACCGTGCCGATGAACCGTGTGGGTCAACCGGCCGAAG
TCGCGTCGGTGGTGAGCTTCCTGATGTCGGACGCAGCCTCTTACGTGACGCGCCAGGTAATCGGCGTCAATGGCGGGATG
ATCTGA

Upstream 100 bases:

>100_bases
AATGCGCGATCGATCACCTCGGTGCGCGTTACGCGGACGCCGTGATCAAGGTGTTTCAACCGGGCGACTTTCACACGTTC
ATCGAAGGGAGTATCAGTTC

Downstream 100 bases:

>100_bases
TGAAGCGTGTCGTCATTACGGGCATGGGCGGCGTCACGGCGCTCGGCAGCCGCTGGGACGAGATCGAAGCGGCACTGAAG
GCAGGCCGCAACGCGGTGCG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MSRRVLVTGASRGIGRAIAYQLAADGFAVSVHCRTGRTEAEAVTAGIAAQGGSARVLQFDVRERAACRDALEADVAAHGP
YYGIVCSAGVTRDAAFPALTDEDWDVVIETGLDAFYNVIHPLTMPMVRAKKGGRIVTIASVSGVIGNRGQVNYSAAKAGL
IGATKALAVELASRSITVNCVAPGLIETGMLQDMPLEHALKTVPMNRVGQPAEVASVVSFLMSDAASYVTRQVIGVNGGM
I

Sequences:

>Translated_241_residues
MSRRVLVTGASRGIGRAIAYQLAADGFAVSVHCRTGRTEAEAVTAGIAAQGGSARVLQFDVRERAACRDALEADVAAHGP
YYGIVCSAGVTRDAAFPALTDEDWDVVIETGLDAFYNVIHPLTMPMVRAKKGGRIVTIASVSGVIGNRGQVNYSAAKAGL
IGATKALAVELASRSITVNCVAPGLIETGMLQDMPLEHALKTVPMNRVGQPAEVASVVSFLMSDAASYVTRQVIGVNGGM
I
>Mature_240_residues
SRRVLVTGASRGIGRAIAYQLAADGFAVSVHCRTGRTEAEAVTAGIAAQGGSARVLQFDVRERAACRDALEADVAAHGPY
YGIVCSAGVTRDAAFPALTDEDWDVVIETGLDAFYNVIHPLTMPMVRAKKGGRIVTIASVSGVIGNRGQVNYSAAKAGLI
GATKALAVELASRSITVNCVAPGLIETGMLQDMPLEHALKTVPMNRVGQPAEVASVVSFLMSDAASYVTRQVIGVNGGMI

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=247, Percent_Identity=36.0323886639676, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=34.5833333333333, Blast_Score=127, Evalue=9e-30,
Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=33.0677290836653, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI4504505, Length=235, Percent_Identity=34.468085106383, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI19923817, Length=246, Percent_Identity=30.4878048780488, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI126723750, Length=247, Percent_Identity=31.5789473684211, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=30.9236947791165, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI66933014, Length=151, Percent_Identity=31.7880794701987, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI59889578, Length=142, Percent_Identity=33.0985915492958, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=31.7460317460317, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=31.2252964426877, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI4758504, Length=150, Percent_Identity=32.6666666666667, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=31.2, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787335, Length=238, Percent_Identity=45.7983193277311, Blast_Score=177, Evalue=6e-46,
Organism=Escherichia coli, GI2367175, Length=242, Percent_Identity=34.297520661157, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=31.3253012048193, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=30.7377049180328, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1790717, Length=244, Percent_Identity=28.6885245901639, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=32.258064516129, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=28.5123966942149, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=28.8, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI87082160, Length=260, Percent_Identity=27.6923076923077, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=28.0769230769231, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=31.3008130081301, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1787905, Length=238, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=244, Percent_Identity=35.655737704918, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI25147288, Length=242, Percent_Identity=35.9504132231405, Blast_Score=124, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=33.59375, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17568967, Length=232, Percent_Identity=32.3275862068966, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=29.9180327868852, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=29.3436293436293, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=27.906976744186, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17536651, Length=249, Percent_Identity=29.718875502008, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=29.3893129770992, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=27.8225806451613, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=28.968253968254, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=29.6153846153846, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=244, Percent_Identity=27.0491803278689, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=257, Percent_Identity=26.4591439688716, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=193, Percent_Identity=28.4974093264249, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=27.0992366412214, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=236, Percent_Identity=27.5423728813559, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=26.5384615384615, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=27.0676691729323, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=258, Percent_Identity=26.3565891472868, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=256, Percent_Identity=27.34375, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=259, Percent_Identity=27.027027027027, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=232, Percent_Identity=31.4655172413793, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324126, Length=186, Percent_Identity=30.1075268817204, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=34.5528455284553, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21355319, Length=241, Percent_Identity=32.3651452282158, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357041, Length=244, Percent_Identity=31.5573770491803, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28571526, Length=246, Percent_Identity=32.1138211382114, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24644339, Length=245, Percent_Identity=30.6122448979592, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=30.6451612903226, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI18859837, Length=242, Percent_Identity=30.9917355371901, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24644337, Length=116, Percent_Identity=37.0689655172414, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR011285
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25060; Mature: 24929

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRVLVTGASRGIGRAIAYQLAADGFAVSVHCRTGRTEAEAVTAGIAAQGGSARVLQFD
CCCEEEEEECCCCHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHCCCCCCCEEEEEC
VRERAACRDALEADVAAHGPYYGIVCSAGVTRDAAFPALTDEDWDVVIETGLDAFYNVIH
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHH
PLTMPMVRAKKGGRIVTIASVSGVIGNRGQVNYSAAKAGLIGATKALAVELASRSITVNC
HHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEHHHHHCCHHHHHHHHHHHHHCCEEEEEE
VAPGLIETGMLQDMPLEHALKTVPMNRVGQPAEVASVVSFLMSDAASYVTRQVIGVNGGM
ECCCHHHCCCCCCCCHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
I
C
>Mature Secondary Structure 
SRRVLVTGASRGIGRAIAYQLAADGFAVSVHCRTGRTEAEAVTAGIAAQGGSARVLQFD
CCEEEEEECCCCHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHCCCCCCCEEEEEC
VRERAACRDALEADVAAHGPYYGIVCSAGVTRDAAFPALTDEDWDVVIETGLDAFYNVIH
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHH
PLTMPMVRAKKGGRIVTIASVSGVIGNRGQVNYSAAKAGLIGATKALAVELASRSITVNC
HHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEHHHHHCCHHHHHHHHHHHHHCCEEEEEE
VAPGLIETGMLQDMPLEHALKTVPMNRVGQPAEVASVVSFLMSDAASYVTRQVIGVNGGM
ECCCHHHCCCCCCCCHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]